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Takeshi Fujino
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Journal Articles

Systematic Evaluation of GAPs and Gefs Identifies ARHGAP45 As a Targetable Leukemia-Specific Dependency

Pu Zhang, Zhendong Cao, Xiangyu Pan, Yuqiao Liu, Cynthia Castro, Won Jun Kim, Takeshi Fujino, Jennifer Lewis, Jahan Rahman, Sanam Shahid, Jasmine S. Um, Erin R. Burns, Bing-Yi Chen, Winson Cai, Juliana Ortiz-Pacheco, Zhuoning Li, Mara Monetti, Anthony F. Daniyan, Christopher R. Vakoc, Omar Abdel-Wahab, Junwei Shi
Journal: Blood
Blood (2024) 144 (Supplement 1): 950.
https://doi.org/10.1182/blood-2024-198954
Published: 2024
Journal Articles

Enhancing CAR T Cell Efficacy By Modulating PI3K Signaling Via a Synthetic CD28 Rheostat

Sanam Shahid, Winson Cai, Erin R. Burns, Jasmine S. Um, Serena Mathew, Sydney Souness, Sarah Yoo, Bing-Yi Chen, Takeshi Fujino, Renier Brentjens, Anthony F. Daniyan
Journal: Blood
Blood (2024) 144 (Supplement 1): 4802.
https://doi.org/10.1182/blood-2024-209964
Published: 2024
Journal Articles

Mis-Splicing Derived Neoantigens and Cognate T Cell Receptors in Splicing Factor Mutant Myeloid Neoplasms

Won Jun Kim, Edie I. Crosse, Emma De Neef, Inaki Etxeberria, Erich Sabio, Eric Wang, Jan Philipp Bewersdorf, Sydney X. Lu, Andrea Belleville, Nina Fox, Cynthia Castro, Pu Zhang, Takeshi Fujino, Jennifer Lewis, Jahan Rahman, Beatrice Zhang, Jacob H. Winick, Alexander M. Lewis, Robert Stanley, Susan Dewolf, Brigita Meskauskaite Urben, Meril Takizawa, Tobias Krause, Henrik Molina, Ronan Chaligne, Priya Koppikar, Jeffrey J. Molldrem, Mathieu Gigoux, Taha Merghoub, Anthony F. Daniyan, Benjamin D. Greenbaum, Christopher A. Klebanoff, Robert K. Bradley, Omar Abdel-Wahab
Journal: Blood
Blood (2024) 144 (Supplement 1): 343.
https://doi.org/10.1182/blood-2024-198639
Published: 2024
Journal Articles

Developing an Optimal Fully-Human CD371-Targeting IL-18 Secreting CAR T Cell for the Treatment of Acute Myeloid Leukemia

Sanam Shahid, Serena Mathew, Sydney Souness, Erin R. Burns, Jasmine S. Um, Sarah Yoo, Winson Cai, Mary Ann Pohl, Takeshi Fujino, Pu Zhang, Jennifer Lewis, Sean M. Devlin, Ivo Lorenz, Renier Brentjens, Anthony F. Daniyan
Journal: Blood
Blood (2024) 144 (Supplement 1): 3406.
https://doi.org/10.1182/blood-2024-194391
Published: 2024
Journal Articles

Development of CAR T Cells Targeting U5 snRNP200 for the Treatment of Acute Myeloid and B-Lymphoid Leukemias

Takeshi Fujino, Jennifer Lewis, Bing-Yi Chen, Quinlan Sievers, Winson Cai, Sarah Yoo, Serena Mathew, Sydney Souness, Erin R. Burns, Jasmine S. Um, Elisa De Stanchina, Qing Chang, Besnik Qeriqi, Kevin Chen, PU Zhang, Susan Dewolf, Alexander M. Lewis, Kenyon Weis, Brianna Gipson, Cynthia Castro, Nina Fox, Satoshi Kaito, Alyssa Fronk, Martin Akerman, Omar Abdel-Wahab, Anthony F. Daniyan
Journal: Blood
Blood (2024) 144 (Supplement 1): 371.
https://doi.org/10.1182/blood-2024-204143
Published: 2024
Journal Articles

Mitochondrial Augmentation of Hematopoietic Stem and Progenitor Cells As a New Therapeutic Approach for Myelodysplasia

Takeshi Fujino, Noa Avni, Neta Kutner, Hanan Khoury, Gat Pozner, Niv Sabath, Cynthia Castro, Nina Fox, Alexander M. Lewis, Steven Tittley, Oren Ziv, Yishai Ofran, Tina Napso, Natalie Yivgi Ohana, Noa Sher, Omar Abdel-Wahab
Journal: Blood
Blood (2024) 144 (Supplement 1): 4772.
https://doi.org/10.1182/blood-2024-200129
Published: 2024
Journal Articles

SETDB1 Suppresses Interferon Responses and NK Cell-Mediated Immunosurveillance Specifically in Monocytic AML

Yu-Hsuan Chang, Keita Yamamoto, Takeshi Fujino, Teh-Wei Wang, Emi Sugimoto, Wenyu Zhang, Tomohiro Yabushita, E. Christine Pietsch, Barbara A. Weir, Ramona Crescenzo, Glenn S. Cowley, Ricardo M. Attar, Ulrike Philippar, Yutaka Enomoto, Yoichi Imai, Toshio Kitamura, Susumu Goyama
Journal: Blood
Blood (2023) 142 (Supplement 1): 713.
https://doi.org/10.1182/blood-2023-177531
Published: 2023
Journal Articles

Mutant ASXL1 Disrupts Paraspeckle Formation through Aberrant Interaction with Nono in Hematopoietic Cells

Yamamoto Keita, MD, Susumu Goyama, MD PhD, Shuhei Asada, MD PhD, Takeshi Fujino, MD, Tomofusa Fukuyama, MD PhD, Yosuke Tanaka, MD, Ayana Kon, MD PhD, Yasuhito Nannya, MD PhD, Seishi Ogawa, MD PhD, Reina Onoguchi, PhD, Nobuyoshi Akimitsu, PhD, Toshio Kitamura, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2514.
https://doi.org/10.1182/blood-2019-125472
Published: 2019
Journal Articles

Mutant ASXL1 Promotes Expansion of the Phenotypic Hematopoietic Stem Cell Compartment

Takeshi Fujino, MD, Susumu Goyama, MD PhD, Yuki Sugiura, PhD, Daichi Inoue, MD PhD, Satoshi Yamasaki, PhD, Akiko Matsumoto, Naru Sato, MD, Hironobu Morinaga, PhD, Shiori Shikata, Tomofusa Fukuyama, MD PhD, Yosuke Tanaka, PhD, Shuhei Asada, MD PhD, Tsuyoshi Fukushima, MD PhD, Hiroaki Honda, MD PhD, Emi K Nishimura, MD PhD, Tatsuhiro Shibata, MD PhD, Makoto Suematsu, MD PhD, Toshio Kitamura, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 821.
https://doi.org/10.1182/blood-2019-127904
Published: 2019