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Journal Articles

Development of CAR T Cells Targeting U5 snRNP200 for the Treatment of Acute Myeloid and B-Lymphoid Leukemias

Blood (2024) 144 (Supplement 1): 371.

https://doi.org/10.1182/blood-2024-204143

Published: 2024

Journal Articles

Mis-Splicing Derived Neoantigens and Cognate T Cell Receptors in Splicing Factor Mutant Myeloid Neoplasms

Blood (2024) 144 (Supplement 1): 343.

https://doi.org/10.1182/blood-2024-198639

Published: 2024

Journal Articles

Systematic Evaluation of GAPs and Gefs Identifies ARHGAP45 As a Targetable Leukemia-Specific Dependency

Blood (2024) 144 (Supplement 1): 950.

https://doi.org/10.1182/blood-2024-198954

Published: 2024

Journal Articles

Developing an Optimal Fully-Human CD371-Targeting IL-18 Secreting CAR T Cell for the Treatment of Acute Myeloid Leukemia

Sanam Shahid, Serena Mathew, Sydney Souness, Erin R. Burns, Jasmine S. Um, Sarah Yoo, Winson Cai, Mary Ann Pohl, Takeshi Fujino, Pu Zhang, Jennifer Lewis, Sean M. Devlin, Ivo Lorenz, Renier Brentjens, Anthony F. Daniyan

Blood (2024) 144 (Supplement 1): 3406.

https://doi.org/10.1182/blood-2024-194391

Published: 2024

Journal Articles

Genome-Wide Mapping of R-Loops in Single Cells Reveals Cell-Type Specific Roles for R-Loops in Hematopoietic Cell Identity

Bin Lu, Pu Zhang, Sisi Chen, Salima Benbarche, Cynthia Castro, Nina Fox, Mohammad Abubakar, Jeetayu Biswas, Ruslan Soldatov, Richard Koche, Omar Abdel-Wahab

Blood (2023) 142 (Supplement 1): 242.

https://doi.org/10.1182/blood-2023-180913

Published: 2023

Journal Articles

Genome-Wide CRISPR/Cas9 Knockout Screen Reveals Novel Gilteritinib Combinations Targeting Oxidative Phosphorylation and De-Novo Purine Biosynthesis Pathways for FLT3-ITD + Acute Myeloid Leukemia

Blood (2022) 140 (Supplement 1): 681–682.

https://doi.org/10.1182/blood-2022-165573

Published: 2022

Journal Articles

Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML

Blood (2021) 138 (15): 1331–1344.

https://doi.org/10.1182/blood.2020007920

Published: 2021

Includes: Supplemental data

Journal Articles

Identification of Novel Synthetic Lethal Partners of NAMPT Inhibitor By CRISPR-Cas9 Screens in Acute Myeloid Leukemia

Pu Zhang, Lindsey Brinton, PhD, James S. Blachly, MD, John C. Byrd, MD, Rosa Lapalombella, PhD

Blood (2019) 134 (Supplement_1): 2072.

https://doi.org/10.1182/blood-2019-129036

Published: 2019

Journal Articles

Long Noncoding RNA Loup Interacts with Runx1 and Regulates Long-Range Transcription of PU.1 in Acute Myeloid Leukemia

Bon Q Trinh, PhD, Pu Zhang, MD, Alexander Ebralidze, PhD, Junyan Zhang, Chan-Shuo Guo, Abby Thurm, Henry Yang, PhD, Ying Li, Annalisa Di Ruscio, MD, Daniel G. Tenen, MD

Blood (2018) 132 (Supplement 1): 1281.

https://doi.org/10.1182/blood-2018-99-120252

Published: 2018

Journal Articles

CRISPR/Cas9 Gene-Edited Hematopoietic Stem Cell Therapy for Sickle Cell Disease

Blood (2017) 130 (Supplement 1): 535.

https://doi.org/10.1182/blood.V130.Suppl_1.535.535

Published: 2017

Journal Articles

The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells

Philipp B. Staber, Pu Zhang, Min Ye, Robert S. Welner, Elena Levantini, Annalisa Di Ruscio, Alexander K. Ebralidze, Christian Bach, Hong Zhang, Junyan Zhang, Katrina Vanura, Ruud Delwel, Henry Yang, Gang Huang, Daniel G. Tenen

Blood (2014) 124 (15): 2391–2399.

https://doi.org/10.1182/blood-2014-01-550855

Published: 2014

Includes: Supplemental data

Journal Articles

The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations

Gang Huang, Xinghui Zhao, Lan Wang, Shannon Elf, Hao Xu, Xinyang Zhao, Goro Sashida, Yue Zhang, Yan Liu, Jennifer Lee, Silvia Menendez, Youyang Yang, Xiaomei Yan, Pu Zhang, Daniel G. Tenen, Motomi Osato, James J.-D. Hsieh, Stephen D. Nimer

Blood (2011) 118 (25): 6544–6552.

https://doi.org/10.1182/blood-2010-11-317909

Published: 2011

Includes: Supplemental data

Journal Articles

Runx1 Induced Chromatin Folding of the PU.1 Gene Locus Is Necessary for Adult Long-Term Hematopoietic Stem Cell Maintenance

Philipp B. Staber, M.D., Pu Zhang, M.D., Min Ye, PhD, Gang Huang, Annalisa Di Ruscio, MD, Alexander K Ebralidze, PhD, Daniel G. Tenen

Blood (2011) 118 (21): 2364.

https://doi.org/10.1182/blood.V118.21.2364.2364

Published: 2011

Journal Articles

PU.1 Is a Downstream Target of C/EBPα in Normal Hematopoiesis and Acute Myeloid Leukemia

Christian Bach, Ph.D., Philipp B. Staber, M.D., Min Ye, Ph.D., Pu Zhang, M.D., Alan D. Friedman, M.D., Ruud Delwel, Ph.D., Daniel G. Tenen

Blood (2011) 118 (21): 1353.

https://doi.org/10.1182/blood.V118.21.1353.1353

Published: 2011

Journal Articles

Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia

Florence C. Guibal, Meritxell Alberich-Jorda, Hideyo Hirai, Alexander Ebralidze, Elena Levantini, Annalisa Di Ruscio, Pu Zhang, Barbara A. Santana-Lemos, Donna Neuberg, Amy J. Wagers, Eduardo M. Rego, Daniel G. Tenen

Blood (2009) 114 (27): 5415–5425.

https://doi.org/10.1182/blood-2008-10-182071

Published: 2009

Includes: Supplemental data

Journal Articles

Autoregulation of the Transcription Factor PU.1 Via Its Evolutionarily Conserved Upstream Regulatory Element Is Critical in Adult Mouse Hematopoiesis.

Philipp B. Staber, M.D., Pu Zhang, M.D., Min Ye, Ph.D., Gang Huang, Ph.D., Boris Bartholdy, Ph.D., Annalisa DiRuscio, M.D., Alexander K. Ebralidze, Ph.D., Daniel G. Tenen, M.D.

Blood (2009) 114 (22): 1468.

https://doi.org/10.1182/blood.V114.22.1468.1468

Published: 2009

Journal Articles

Increasing C/Ebpα Expression Regulates the Transition of Hematopoietic Stem Cells During Development.

Min Ye, PhD, Hong Zhang, PhD, Pu Zhang, MD, Daniel G. Tenen, MD

Blood (2009) 114 (22): 1506.

https://doi.org/10.1182/blood.V114.22.1506.1506

Published: 2009

Journal Articles

Genetics and Epigenetics of the PU.1 Upstream Regulatory Element: AML1 Binding Sites Are Critical for Leuekmia Induced by the AML/ETO9a Fusion Oncogene

Pu Zhang, MD, Gang Huang, Alex Ebralidze, Jun-Yan Zhang, Annalisa DiRuscio, Chris Hetherington, Elena Levantini, Daniel G. Tenen

Blood (2008) 112 (11): 594.

https://doi.org/10.1182/blood.V112.11.594.594

Published: 2008

Journal Articles

Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1

Bas J. Wouters, Meritxell Alberich Jordà, Karen Keeshan, Irene Louwers, Claudia A. J. Erpelinck-Verschueren, Dennis Tielemans, Anton W. Langerak, Yiping He, Yumi Yashiro-Ohtani, Pu Zhang, Christopher J. Hetherington, Roel G. W. Verhaak, Peter J. M. Valk, Bob Löwenberg, Daniel G. Tenen, Warren S. Pear, Ruud Delwel

Blood (2007) 110 (10): 3706–3714.

https://doi.org/10.1182/blood-2007-02-073486

Published: 2007

Includes: Supplemental data

Journal Articles

Regulation of the PU.1 Gene by Sense and Functional Antisense RNAs Generated through the Same Chromatin Architecture.

Alex Ebralidze, PhD, Pu Zhang, MD, Frank Rosenbauer, Ph.D., Gang Huang, Ph.D., Ulrich Steidl, M.D., Tajhal Dayaram, B.S., Florence Guibal, Ph.D., Johanna Klupp, B.S., Dana Neel, Constanze Bonifer, Ph.D., Daniel G. Tenen, M.D.

Blood (2006) 108 (11): 781.

https://doi.org/10.1182/blood.V108.11.781.781

Published: 2006

NARROW

Development of CAR T Cells Targeting U5 snRNP200 for the Treatment of Acute Myeloid and B-Lymphoid Leukemias

Mis-Splicing Derived Neoantigens and Cognate T Cell Receptors in Splicing Factor Mutant Myeloid Neoplasms

Systematic Evaluation of GAPs and Gefs Identifies ARHGAP45 As a Targetable Leukemia-Specific Dependency

Developing an Optimal Fully-Human CD371-Targeting IL-18 Secreting CAR T Cell for the Treatment of Acute Myeloid Leukemia

Genome-Wide Mapping of R-Loops in Single Cells Reveals Cell-Type Specific Roles for R-Loops in Hematopoietic Cell Identity

Genome-Wide CRISPR/Cas9 Knockout Screen Reveals Novel Gilteritinib Combinations Targeting Oxidative Phosphorylation and De-Novo Purine Biosynthesis Pathways for FLT3-ITD + Acute Myeloid Leukemia

Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML

Identification of Novel Synthetic Lethal Partners of NAMPT Inhibitor By CRISPR-Cas9 Screens in Acute Myeloid Leukemia

Long Noncoding RNA Loup Interacts with Runx1 and Regulates Long-Range Transcription of PU.1 in Acute Myeloid Leukemia

CRISPR/Cas9 Gene-Edited Hematopoietic Stem Cell Therapy for Sickle Cell Disease

The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells

The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations

Runx1 Induced Chromatin Folding of the PU.1 Gene Locus Is Necessary for Adult Long-Term Hematopoietic Stem Cell Maintenance

PU.1 Is a Downstream Target of C/EBPα in Normal Hematopoiesis and Acute Myeloid Leukemia

Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia

Autoregulation of the Transcription Factor PU.1 Via Its Evolutionarily Conserved Upstream Regulatory Element Is Critical in Adult Mouse Hematopoiesis.

Increasing C/Ebpα Expression Regulates the Transition of Hematopoietic Stem Cells During Development.

Genetics and Epigenetics of the PU.1 Upstream Regulatory Element: AML1 Binding Sites Are Critical for Leuekmia Induced by the AML/ETO9a Fusion Oncogene

Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1

Regulation of the PU.1 Gene by Sense and Functional Antisense RNAs Generated through the Same Chromatin Architecture.

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American Society of Hematology

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American Society of Hematology

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