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Bin Lu
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Journal Articles

Phase Ib Study of PRT543, an Oral Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor, in Patients with Relapsed or Refractory, Splicing Factor-Mutant Myeloid Malignancies

Jan Philipp Bewersdorf, Xiaoli Mi, Bin Lu, Andrew T. Kuykendall, David Sallman, Manish Patel, Don A. Stevens, Alexander Philipovskiy, Grerk Sutamtewagul, Lucia Masarova, Gina Keiffer, Amit Verma, Neha Bhagwat, Diane Heiser, Sunhee Ro, Wan-Jen Hong, Omar Abdel-Wahab, Eytan M. Stein
Journal: Blood
Blood (2024) 144 (Supplement 1): 3215.
https://doi.org/10.1182/blood-2024-198495
Published: 2024
Journal Articles

Genome-Wide Mapping of R-Loops in Single Cells Reveals Cell-Type Specific Roles for R-Loops in Hematopoietic Cell Identity

Bin Lu, Pu Zhang, Sisi Chen, Salima Benbarche, Cynthia Castro, Nina Fox, Mohammad Abubakar, Jeetayu Biswas, Ruslan Soldatov, Richard Koche, Omar Abdel-Wahab
Journal: Blood
Blood (2023) 142 (Supplement 1): 242.
https://doi.org/10.1182/blood-2023-180913
Published: 2023
Journal Articles

Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo

Yusuke Tarumoto, Shan Lin, Jinhua Wang, Joseph P. Milazzo, Yali Xu, Bin Lu, Zhaolin Yang, Yiliang Wei, Sofya Polyanskaya, Mark Wunderlich, Nathanael S. Gray, Kimberly Stegmaier, Christopher R. Vakoc
Journal: Blood
Blood (2020) 135 (1): 56–70.
https://doi.org/10.1182/blood.2019001576
Published: 2020
Includes: Supplemental data
Journal Articles

Enhancer dysfunction in leukemia

Anand S. Bhagwat, Bin Lu, Christopher R. Vakoc
Journal: Blood
Blood (2018) 131 (16): 1795–1804.
https://doi.org/10.1182/blood-2017-11-737379
Published: 2018
Journal Articles

ANP32A Regulates Histone 3 Acetylation and Promotes Leukemogenesis in AML

Xuejing Yang, Xueqin Sun, PhD, Bin Lu, PhD, Qianfei Wang, PhD, Zan Huang, PhD
Journal: Blood
Blood (2016) 128 (22): 3917.
https://doi.org/10.1182/blood.V128.22.3917.3917
Published: 2016
Journal Articles

ANP32A Dysregulation Contributes to Abnormal Megakaryopoiesis in Acute Megakaryoblastic Leukemia

Xueqin Sun, PhD, Bin Lu, PhD, Zan Huang
Journal: Blood
Blood (2015) 126 (23): 1231.
https://doi.org/10.1182/blood.V126.23.1231.1231
Published: 2015
Journal Articles

ANP32A Dysregulation Involves Histone Modifications and Contributes to Myeloid Leukemia

Bin Lu, PhD, Xueqin Sun, PhD, John Crispino, PhD, Zan Huang
Journal: Blood
Blood (2015) 126 (23): 2456.
https://doi.org/10.1182/blood.V126.23.2456.2456
Published: 2015
Journal Articles

Novel Function Of Chromosome 7 Open Reading Frame 41 Gene To Promote Leukemic Megakaryocyte Differentiation By Modulating TPA-Induced MAPK/ERK, SAPK/JNK, and NF-κB Signaling

Xueqin Sun, Bin Lu, Zan Huang
Journal: Blood
Blood (2013) 122 (21): 1209.
https://doi.org/10.1182/blood.V122.21.1209.1209
Published: 2013
Journal Articles

The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives

Steven H. Bernstein, Sundararajan Venkatesh, Min Li, Jae Lee, Bin Lu, Shannon P. Hilchey, Kimberly M. Morse, Hollie M. Metcalfe, Jolanta Skalska, Michael Andreeff, Paul S. Brookes, Carolyn K. Suzuki
Journal: Blood
Blood (2012) 119 (14): 3321–3329.
https://doi.org/10.1182/blood-2011-02-340075
Published: 2012
Includes: Supplemental data