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Paul S. Brookes
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Journal Articles

The Rheumatoid Arthritis Drug Auranofin Has Significant in Vitro Activity in MCL and DLCL and Is Synergistic with a Glutathione Depleting Agent

Jolanta Skalska, PhD, Michelle M. Kiebala, PhD, Shannon P. Hilchey, PhD, Yun Dai, MD, PhD, Steven Grant, MD, Paul S. Brookes, PhD, Derick R. Peterson, PhD, Sanjay B. Maggirwar, PhD, Steven H. Bernstein, MD
Journal: Blood
Blood (2012) 120 (21): 1658.
https://doi.org/10.1182/blood.V120.21.1658.1658
Published: 2012
Journal Articles

Bcl-2 Inhibitor ABT-263 Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells

Eleni D Lagadinou, MD/PhD, Alexander Sach, BS, Kevin P Callahan, PhD, Randall M. Rossi, MS, Sarah Neering, MS, Shanshan Pei, BS, Kristen O'Dwyer, MD, Jane L. Liesveld, MD, Paul S. Brookes, PhD, Michael W. Becker, MD, Craig T. Jordan, PhD
Journal: Blood
Blood (2012) 120 (21): 206.
https://doi.org/10.1182/blood.V120.21.206.206
Published: 2012
Journal Articles

The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives

Steven H. Bernstein, Sundararajan Venkatesh, Min Li, Jae Lee, Bin Lu, Shannon P. Hilchey, Kimberly M. Morse, Hollie M. Metcalfe, Jolanta Skalska, Michael Andreeff, Paul S. Brookes, Carolyn K. Suzuki
Journal: Blood
Blood (2012) 119 (14): 3321–3329.
https://doi.org/10.1182/blood-2011-02-340075
Published: 2012
Includes: Supplemental data
Journal Articles

Modulation of Cell Surface Protein Free Thiols; A Potential Novel Mechanism of Action of the Sesquiterpene Lactone Parthenolide in Non-Hodgkin's Lymphoma.

Jolanta Skalska, PhD, Paul S Brookes, PhD, S. M Nadtochy, Shannon Hilchey, PhD, Craig T. Jordan, PhD, Monica L. Guzman, PhD, Sanjay Maggirwar, PhD, Margaret M Briehl, PhD, Steven H. Bernstein, MD
Journal: Blood
Blood (2009) 114 (22): 3774.
https://doi.org/10.1182/blood.V114.22.3774.3774
Published: 2009
Journal Articles

The Triterpenoid 2-Cyano-3,12-Dioxooleana-1,9-Dien-28-Oic Acid and Its Derivatives Inhibit Mitochondrial Lon Protease Activity: A Potential Novel Pathway for the Induction of Lymphoma Cell Death.

Steven H. Bernstein, MD, Bin Lin, PhD, Shannon Hilchey, PhD, N. Villaluna, L. Chen, K. Madura, Kim Morse, Hollie Metcalf, Michael Andreeff, MD, PhD, Paul S Brookes, PhD, Carolyn K Suzuki, PhD
Journal: Blood
Blood (2009) 114 (22): 414.
https://doi.org/10.1182/blood.V114.22.414.414
Published: 2009