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Journal Articles

The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations

Gang Huang, Xinghui Zhao, Lan Wang, Shannon Elf, Hao Xu, Xinyang Zhao, Goro Sashida, Yue Zhang, Yan Liu, Jennifer Lee, Silvia Menendez, Youyang Yang, Xiaomei Yan, Pu Zhang, Daniel G. Tenen, Motomi Osato, James J.-D. Hsieh, Stephen D. Nimer

Blood (2011) 118 (25): 6544–6552.

https://doi.org/10.1182/blood-2010-11-317909

Published: 2011

Includes: Supplemental data

Journal Articles

A Novel Function of MLL in the S Phase Checkpoint: MLL Is Phosphorylated by ATR Upon DNA Damage, Which Blocks Its Degradation by the SCF skp2 Proteasome, Leading to Its Accumulation That Directly Inhibits DNA Replication.

Han Liu, Shugaku Takeda, Rakesh Kumar, Todd Westergard, Tej Pandita, Emily Cheng, MD, PhD, James J.-D. Hsieh, MD, PhD

Blood (2009) 114 (22): 450.

https://doi.org/10.1182/blood.V114.22.450.450

Published: 2009

Journal Articles

MLL5 governs hematopoiesis: a step closer

Han Liu, Todd D. Westergard, James J.-D. Hsieh

Blood (2009) 113 (7): 1395–1396.

https://doi.org/10.1182/blood-2008-11-185801

Published: 2009

Journal Articles

The Role of MLL in DNA Damage Checkpoint and Its Implication in Leukemogenesis

Han Liu, PhD, Todd D Westergard, David Y Chen, Emily H.-Y. Cheng, MD, PhD, James J.-D. Hsieh, MD, PhD

Blood (2008) 112 (11): 5332.

https://doi.org/10.1182/blood.V112.11.5332.5332

Published: 2008

Journal Articles

Bimodal Degradation of MLL Protein by the Cell Cycle SCF Skp2 and APC Cdc20 E3 Lilgases Assures Cell Cycle Execution: A Critical Regulatory Circuit Lost in Leukemogenic MLL-Fusions.

Han Liu, PhD, David Chen, Todd Westergard, Shugaku Takeda, Satoru Sasagawa, PhD, Emily H.-Y. Cheng, MD PhD, James J.-D. Hsieh, MD, PhD

Blood (2007) 110 (11): 828.

https://doi.org/10.1182/blood.V110.11.828.828

Published: 2007

NARROW

The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations

A Novel Function of MLL in the S Phase Checkpoint: MLL Is Phosphorylated by ATR Upon DNA Damage, Which Blocks Its Degradation by the SCF skp2 Proteasome, Leading to Its Accumulation That Directly Inhibits DNA Replication.

MLL5 governs hematopoiesis: a step closer

The Role of MLL in DNA Damage Checkpoint and Its Implication in Leukemogenesis

Bimodal Degradation of MLL Protein by the Cell Cycle SCF Skp2 and APC Cdc20 E3 Lilgases Assures Cell Cycle Execution: A Critical Regulatory Circuit Lost in Leukemogenic MLL-Fusions.

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ASH Publications

American Society of Hematology

The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations

A Novel Function of MLL in the S Phase Checkpoint: MLL Is Phosphorylated by ATR Upon DNA Damage, Which Blocks Its Degradation by the SCF skp2 Proteasome, Leading to Its Accumulation That Directly Inhibits DNA Replication.

MLL5 governs hematopoiesis: a step closer

The Role of MLL in DNA Damage Checkpoint and Its Implication in Leukemogenesis

Bimodal Degradation of MLL Protein by the Cell Cycle SCF Skp2 and APC Cdc20 E3 Lilgases Assures Cell Cycle Execution: A Critical Regulatory Circuit Lost in Leukemogenic MLL-Fusions.

Email alerts

ASH Publications

American Society of Hematology

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