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Jeffrey R. Gardner
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Journal Articles

Genomic Analysis of Serial Samples from CLL Patients Identifies Clonal Events Associated with Disease Progression

Jeffrey R Gardner, BS, MBA, Michelle Nahas, PhD, Jie He, PhD, Shlomzion Aumann, Mithat Gonen, Minal Patel, Kristina M. Knapp, BS, Maria Lia Palomba, MD, Roman Yelensky, PhD, Amy L Donahue, MS, Geoff Otto, PhD, Maria Arcila, MD, Nicole Lamanna, Mark G. Frattini, MD PhD, Ahmet Dogan, MD PhD, Jae H Park, MD, Doron Lipson, PhD, Martin S. Tallman, MD, Ross L. Levine, MD, Philip J. Stephens, PhD, Marcel R. M. van den Brink, MD PhD, Mark L Heaney, MD PhD, Vincent A. Miller, MD, Andrew D. Zelenetz, MD PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2014) 124 (21): 1954.
https://doi.org/10.1182/blood.V124.21.1954.1954
Published: 2014
Journal Articles

Extensive High-Depth Sequencing Of Longitudinal CLL Samples Identifies Frequent Mutations In MAP Kinase Signaling and Novel Mutations Activating Notch and Beta-Catenin

Jeffrey R Gardner, MBA, Michelle K. Nahas, PhD, Jie He, PhD, Minal Patel, Kristina M. Knapp, BS, M. Lia Palomba, MD, Roman Yelensky, PhD, Amy L Donahue, MS, Geoff A. Otto, PhD, Maria Arcila, MD, Ahmet Dogan, MD, PhD, Jae H Park, MD, Andrew D. Zelenetz, MD, PhD, Doron Lipson, PhD, Martin S. Tallman, MD, Ross L. Levine, MD, Philip J. Stephens, PhD, Marcel R. M. van den Brink, MD, PhD, Vincent A. Miller, MD, Mark L Heaney, MD, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2013) 122 (21): 2858.
https://doi.org/10.1182/blood.V122.21.2858.2858
Published: 2013
Journal Articles

Aerobic Glycolysis Predicts Outcome in Early Chronic Lymphocytic Leukemia.

Jeffrey R Gardner, MBA, Sean Devlin, PhD, Kristina Knapp, Francesco Bauli, MS, Nicole Lamanna, MD, Mark G. Frattini, MD, PhD, Renier J Brentjens, MD, PhD, Peter G. Maslak, M.D., Joseph G. Jurcic, MD, Mark Weiss, MD, David A. Scheinberg, MD, PhD, Mark Heaney, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2482.
https://doi.org/10.1182/blood.V120.21.2482.2482
Published: 2012
Journal Articles

Elevated Mitochondrial Membrane Potential in CLL Cells Is Associated with a more aggressive Natural History

Jeffrey R Gardner, MBA, Kristina Knapp, Mark G. Frattini, MD, PhD, Nicole Lamanna, MD, Renier Brentjens, MD, PhD, Joseph G Jurcic, MD, Peter G. Maslak, M.D., Ellin Berman, MD, Mark Weiss, MD, David A. Scheinberg, MD, PhD, Mark Heaney, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1765.
https://doi.org/10.1182/blood.V118.21.1765.1765
Published: 2011
Journal Articles

High Mitochondrial Membrane Potential Identifies Patients with Myeloproliferative Neoplasms with a More Aggressive Natural History

Jeffrey R Gardner, MBA, Omar Abdel-Wahab, Mark Frattini, MD, Joseph G Jurcic, MD, Kristina Knapp, Todd L. Rosenblat, MD, MS, Gerald A. Soff, MD, Ross Levine, MD, Mark Heaney, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1992.
https://doi.org/10.1182/blood.V116.21.1992.1992
Published: 2010
Journal Articles

Efficacy of the JAK2 inhibitor INCB16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis

Priya Koppikar, Omar Abdel-Wahab, Cyrus Hedvat, Sachie Marubayashi, Jay Patel, Aviva Goel, Nicole Kucine, Jeffrey R. Gardner, Andrew P. Combs, Kris Vaddi, Patrick J. Haley, Timothy C. Burn, Mark Rupar, Jacqueline F. Bromberg, Mark L. Heaney, Elisa de Stanchina, Jordan S. Fridman, Ross L. Levine
Journal: Blood
Blood (2010) 115 (14): 2919–2927.
https://doi.org/10.1182/blood-2009-04-218842
Published: 2010
Includes: Supplemental data
Journal Articles

Soluble GM-CSF Receptor α Is Cytotoxic to Myeloid Cells in a Manner That Is Independent of GM-CSF Binding Inhibition.

Jeffrey R Gardner, BS, MBA, Mark Lawrence Heaney, MD, PhD, Linghao Niu, PhD
Journal: Blood
Blood (2009) 114 (22): 3618.
https://doi.org/10.1182/blood.V114.22.3618.3618
Published: 2009
Journal Articles

The BH3-only mimetic ABT-737 synergizes the antineoplastic activity of proteasome inhibitors in lymphoid malignancies

Luca Paoluzzi, Mithat Gonen, Govind Bhagat, Richard R. Furman, Jeffrey R. Gardner, Luigi Scotto, Volodia D. Gueorguiev, Mark L. Heaney, Katia Manova, Owen A. O'Connor
Journal: Blood
Blood (2008) 112 (7): 2906–2916.
https://doi.org/10.1182/blood-2007-12-130781
Published: 2008
Journal Articles

Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma

Luca Paoluzzi, Mithat Gonen, Jeffrey R. Gardner, Jill Mastrella, Dajun Yang, Jon Holmlund, Mel Sorensen, Lance Leopold, Katia Manova, Guido Marcucci, Mark L. Heaney, Owen A. O'Connor
Journal: Blood
Blood (2008) 111 (11): 5350–5358.
https://doi.org/10.1182/blood-2007-12-129833
Published: 2008
Journal Articles

Malignant Cells in the Marrow and Blood of Patients with Hematopoietic Malignancies Have Higher Mitochondrial Membrane Potential as Measured with the Potentiometric Dye JC-1.

Jeffrey R. Gardner, Rong H. Zhang, Ruth Rose, Sue McKenzie, Peter Maslak, Mark L. Heaney
Journal: Blood
Blood (2006) 108 (11): 2367.
https://doi.org/10.1182/blood.V108.11.2367.2367
Published: 2006
Journal Articles

Vitamin C Antagonizes the Cytotoxic Effects of Antineoplastic Drugs.

Mark L. Heaney, MD, PhD, Jeffrey R. Gardner, Nicos Karasavvas, PhD, David W. Golde, MD, David A. Scheinberg, MD, PhD, Emily A. Smith, Owen A. O’Connor, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 498.
https://doi.org/10.1182/blood.V106.11.498.498
Published: 2005