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David H. Segal
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Journal Articles

IMiDs prime myeloma cells for daratumumab-mediated cytotoxicity through loss of Ikaros and Aiolos

Pasquale L. Fedele, Simon N. Willis, Yang Liao, Michael S. Low, Jai Rautela, David H. Segal, Jia-Nan Gong, Nicholas D. Huntington, Wei Shi, David C. S. Huang, George Grigoriadis, Julie Tellier, Stephen L. Nutt
Journal: Blood
Blood (2018) 132 (20): 2166–2178.
https://doi.org/10.1182/blood-2018-05-850727
Published: 2018
Includes: Supplemental data
Journal Articles

The Immunomodulatory Drugs, through Loss of Ikaros and Aiolos, Derepress CD38 and Functionally Synergise with Daratumumab

Pasquale L. Fedele, FRACP, FRCPA, Simon Willis, PhD, Michael S. Low, MBBS, Jai Rautela, PhD, David H. Segal, PhD, Jianan Gong, PhD, Yang Liao, PhD, Nicholas Huntington, PhD, Wei Shi, PhD, David Huang, MBBS PhD, George Grigoriadis, MBBS PhDFRACP FRCPA, Julie Tellier, PhD, Stephen Nutt, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1801.
https://doi.org/10.1182/blood.V130.Suppl_1.1801.1801
Published: 2017
Journal Articles

Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription

Daniel Thomas, Jason A. Powell, Francois Vergez, David H. Segal, Nhu-Y. N. Nguyen, Adele Baker, Tse-Chieh Teh, Emma F. Barry, Jean-Emmanuel Sarry, Erwin M. Lee, Tracy L. Nero, Anissa M. Jabbour, Giovanna Pomilio, Benjamin D. Green, Stéphane Manenti, Stefan P. Glaser, Michael W. Parker, Angel F. Lopez, Paul G. Ekert, Richard B. Lock, David C. S. Huang, Susie K. Nilsson, Christian Récher, Andrew H. Wei, Mark A. Guthridge
Journal: Blood
Blood (2013) 122 (5): 738–748.
https://doi.org/10.1182/blood-2012-08-447441
Published: 2013
Includes: Supplemental data