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Journal Articles

Loss of IRF4 Results in Multiple Myeloma Cell Apoptosis through the Transcriptional up-Regulation of the BH3-Only Proteins Bmf and BIM

Pasquale L. Fedele, MBBS PhDFRACP FRCPA, Yang Liao, PhD, Jianan Gong, PhD, Mark van Delft, PhD, Michael S.Y. Low, MBBS PhDFRACP FRCPA, Lin Tai, PhD, Marco J Herold, PhD, Julie Tellier, PhD, George Grigoriadis, MBBS PhDFRACP FRCPA, David C.S. Huang, MBBS MRCP PhD, Wei Shi, PhD, Stephen Nutt, PhD, Simon Willis, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3103.
https://doi.org/10.1182/blood-2019-126417
Published: 2019
Journal Articles

IMiDs prime myeloma cells for daratumumab-mediated cytotoxicity through loss of Ikaros and Aiolos

Pasquale L. Fedele, Simon N. Willis, Yang Liao, Michael S. Low, Jai Rautela, David H. Segal, Jia-Nan Gong, Nicholas D. Huntington, Wei Shi, David C. S. Huang, George Grigoriadis, Julie Tellier, Stephen L. Nutt
Journal: Blood
Blood (2018) 132 (20): 2166–2178.
https://doi.org/10.1182/blood-2018-05-850727
Published: 2018
Includes: Supplemental data
Journal Articles

The Immunomodulatory Drugs, through Loss of Ikaros and Aiolos, Derepress CD38 and Functionally Synergise with Daratumumab

Pasquale L. Fedele, FRACP, FRCPA, Simon Willis, PhD, Michael S. Low, MBBS, Jai Rautela, PhD, David H. Segal, PhD, Jianan Gong, PhD, Yang Liao, PhD, Nicholas Huntington, PhD, Wei Shi, PhD, David Huang, MBBS PhD, George Grigoriadis, MBBS PhDFRACP FRCPA, Julie Tellier, PhD, Stephen Nutt, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1801.
https://doi.org/10.1182/blood.V130.Suppl_1.1801.1801
Published: 2017