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Journal Articles

A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates

Keegan S. Cooke, Beth Hinkle, Hossein Salimi-Moosavi, Ian Foltz, Chadwick King, Palaniswami Rathanaswami, Aaron Winters, Shirley Steavenson, C. Glenn Begley, Graham Molineux, Barbra J. Sasu

Blood (2013) 122 (17): 3054–3061.

https://doi.org/10.1182/blood-2013-06-505792

Published: 2013

Includes: Supplemental data

Journal Articles

Potency and Selectivity Assessment of Small Molecules Against Janus Kinase (JAK) 2: Widely Used AG490 Inhibitor Is Neither Potent Nor Selective for JAK2

Angus Sinclair, Ivonne Archibeque, Jinghui Zhan, Liqin Liu, Renee Emkey, Elizabeth Doherty, C. Glenn Begley, MD, PhD

Blood (2011) 118 (21): 4780.

https://doi.org/10.1182/blood.V118.21.4780.4780

Published: 2011

Journal Articles

Epor Is Not Expressed or Functional in Primary Tumor Cells Isolated Directly From Human Primary and Metastatic Epithelial Tumors Including Breast, Non-Small Cell Lung, Colorectal, and Ovarian Tissues

Ian McCaffery, PhD, John M Rossi, Katherine L Paweletz, Yanyan Tudor, Steve Elliott, V Dan Fitzpatrick, PhD, C. Glenn Begley, PhD, MBBS, FRACP, FRCPA, Scott D Patterson, PhD

Blood (2011) 118 (21): 4781.

https://doi.org/10.1182/blood.V118.21.4781.4781

Published: 2011

Journal Articles

Absence of functional EpoR expression in human tumor cell lines

Susan Swift, Aaron R. Ellison, Paul Kassner, Ian McCaffery, John Rossi, Angus M. Sinclair, C. Glenn Begley, Steven Elliott

Blood (2010) 115 (21): 4254–4263.

https://doi.org/10.1182/blood-2009-10-248674

Published: 2010

Includes: Supplemental data

Journal Articles

Functional erythropoietin receptor is undetectable in endothelial, cardiac, neuronal, and renal cells

Angus M. Sinclair, Angela Coxon, Ian McCaffery, Stephen Kaufman, Katherine Paweletz, Liqin Liu, Leigh Busse, Susan Swift, Steven Elliott, C. Glenn Begley

Blood (2010) 115 (21): 4264–4272.

https://doi.org/10.1182/blood-2009-10-248666

Published: 2010

Includes: Supplemental data

Journal Articles

Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia

Barbra J. Sasu, Keegan S. Cooke, Tara L. Arvedson, Cherylene Plewa, Aaron R. Ellison, Jackie Sheng, Aaron Winters, Todd Juan, Hongyan Li, C. Glenn Begley, Graham Molineux

Blood (2010) 115 (17): 3616–3624.

https://doi.org/10.1182/blood-2009-09-245977

Published: 2010

Journal Articles

The Shc-binding site of the β c subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis

Hayley S. Ramshaw, Mark A. Guthridge, Frank C. Stomski, Emma F. Barry, Lisa Ooms, Christina A. Mitchell, C. Glenn Begley, Angel F. Lopez

Blood (2007) 110 (10): 3582–3590.

https://doi.org/10.1182/blood-2007-01-070391

Published: 2007

Includes: Supplemental data

Journal Articles

NOTCH1 pathway activation is an early hallmark of SCL T leukemogenesis

Joachim R. Göthert, Rachael L. Brake, Monique Smeets, Ulrich Dührsen, C. Glenn Begley, David J. Izon

Blood (2007) 110 (10): 3753–3762.

https://doi.org/10.1182/blood-2006-12-063644

Published: 2007

Includes: Supplemental data

Journal Articles

A Novel Cellular Pathway of SCL T-Leukemogenesis Revealed by a Conditional Transgenic Mouse Model.

Joachim R. Gothert, Rachael Brake, C. Glenn Begley, David J. Izon

Blood (2006) 108 (11): 1835.

https://doi.org/10.1182/blood.V108.11.1835.1835

Published: 2006

Journal Articles

Anti-Epo receptor antibodies do not predict Epo receptor expression

Steve Elliott, Leigh Busse, Michael B. Bass, Hsieng Lu, Ildiko Sarosi, Angus M. Sinclair, Chris Spahr, Moonkyoung Um, Gwyneth Van, C. Glenn Begley

Blood (2006) 107 (5): 1892–1895.

https://doi.org/10.1182/blood-2005-10-4066

Published: 2006

Includes: Supplemental data

Journal Articles

In vivo fate-tracing studies using the Scl stem cell enhancer: embryonic hematopoietic stem cells significantly contribute to adult hematopoiesis

Joachim R. Göthert, Sonja E. Gustin, Mark A. Hall, Anthony R. Green, Berthold Göttgens, David J. Izon, C. Glenn Begley

Blood (2005) 105 (7): 2724–2732.

https://doi.org/10.1182/blood-2004-08-3037

Published: 2005

Journal Articles

The SCL Transcription Factor Supports Erythroid Cell Survival and Differentiation Downstream of the Erythropoietin Receptor.

Rachid Lahlil, Richard Martin, Peter D. Aplan, C. Glenn Begley, Jacqueline E. Damen, Gerald Krystal, Trang Hoang

Blood (2004) 104 (11): 818.

https://doi.org/10.1182/blood.V104.11.818.818

Published: 2004

Journal Articles

In Vivo Fate Tracing Studies Using the SCL Stem Cell Enhancer: Embryonic Hematopoietic Stem Cells Significantly Contribute to Adult Hematopoiesis.

Joachim R. Gothert, Sonja E. Gustin, Mark A. Hall, Anthony R. Green, Berthold Gottgens, David J. Izon, C. Glenn Begley

Blood (2004) 104 (11): 559.

https://doi.org/10.1182/blood.V104.11.559.559

Published: 2004

Journal Articles

Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium

Joachim R. Göthert, Sonja E. Gustin, J. Anke M. van Eekelen, Uli Schmidt, Mark A. Hall, Stephen M. Jane, Anthony R. Green, Berthold Göttgens, David J. Izon, C. Glenn Begley

Blood (2004) 104 (6): 1769–1777.

https://doi.org/10.1182/blood-2003-11-3952

Published: 2004

Journal Articles

SCL is required for normal function of short-term repopulating hematopoietic stem cells

David J. Curtis, Mark A. Hall, Leonie J. Van Stekelenburg, Lorraine Robb, Stephen M. Jane, C. Glenn Begley

Blood (2004) 103 (9): 3342–3348.

https://doi.org/10.1182/blood-2003-09-3202

Published: 2004

Journal Articles

Recombinant human thrombopoietin: basic biology and evaluation of clinical studies

David J. Kuter, C. Glenn Begley

Blood (2002) 100 (10): 3457–3469.

https://doi.org/10.1182/blood.V100.10.3457

Published: 2002

Journal Articles

The SCL complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1

Eric Lécuyer, Sabine Herblot, Marianne Saint-Denis, Richard Martin, C. Glenn Begley, Catherine Porcher, Stuart H. Orkin, Trang Hoang

Blood (2002) 100 (7): 2430–2440.

https://doi.org/10.1182/blood-2002-02-0568

Published: 2002

Journal Articles

Development of pancytopenia with neutralizing antibodies to thrombopoietin after multicycle chemotherapy supported by megakaryocyte growth and development factor

Russell L. Basser, Elizabeth O'Flaherty, Michael Green, Maria Edmonds, Janet Nichol, Dora M. Menchaca, Brian Cohen, C. Glenn Begley

Blood (2002) 99 (7): 2599–2602.

https://doi.org/10.1182/blood.V99.7.2599

Published: 2002

Journal Articles

Reassessment of interactions between hematopoietic receptors using common beta-chain and interleukin-3–specific receptor beta-chain–null cells: no evidence of functional interactions with receptors for erythropoietin, granulocyte colony-stimulating factor, or stem cell factor

Clare L. Scott, Lorraine Robb, Bette Papaevangeliou, Rachel Mansfield, Nicos A. Nicola, C. Glenn Begley

Blood (2000) 96 (4): 1588–1590.

https://doi.org/10.1182/blood.V96.4.1588

Published: 2000

Journal Articles

The residual megakaryocyte and platelet production in c-Mpl–deficient mice is not dependent on the actions of interleukin-6, interleukin-11, or leukemia inhibitory factor

Timothy Gainsford, Harshal Nandurkar, Donald Metcalf, Lorraine Robb, C. Glenn Begley, Warren S. Alexander

Blood (2000) 95 (2): 528–534.

https://doi.org/10.1182/blood.V95.2.528

Published: 2000

NARROW

A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates

Potency and Selectivity Assessment of Small Molecules Against Janus Kinase (JAK) 2: Widely Used AG490 Inhibitor Is Neither Potent Nor Selective for JAK2

Epor Is Not Expressed or Functional in Primary Tumor Cells Isolated Directly From Human Primary and Metastatic Epithelial Tumors Including Breast, Non-Small Cell Lung, Colorectal, and Ovarian Tissues

Absence of functional EpoR expression in human tumor cell lines

Functional erythropoietin receptor is undetectable in endothelial, cardiac, neuronal, and renal cells

Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia

The Shc-binding site of the β c subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis

NOTCH1 pathway activation is an early hallmark of SCL T leukemogenesis

A Novel Cellular Pathway of SCL T-Leukemogenesis Revealed by a Conditional Transgenic Mouse Model.

Anti-Epo receptor antibodies do not predict Epo receptor expression

In vivo fate-tracing studies using the Scl stem cell enhancer: embryonic hematopoietic stem cells significantly contribute to adult hematopoiesis

The SCL Transcription Factor Supports Erythroid Cell Survival and Differentiation Downstream of the Erythropoietin Receptor.

In Vivo Fate Tracing Studies Using the SCL Stem Cell Enhancer: Embryonic Hematopoietic Stem Cells Significantly Contribute to Adult Hematopoiesis.

Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium

SCL is required for normal function of short-term repopulating hematopoietic stem cells

Recombinant human thrombopoietin: basic biology and evaluation of clinical studies

The SCL complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1

Development of pancytopenia with neutralizing antibodies to thrombopoietin after multicycle chemotherapy supported by megakaryocyte growth and development factor

Reassessment of interactions between hematopoietic receptors using common beta-chain and interleukin-3–specific receptor beta-chain–null cells: no evidence of functional interactions with receptors for erythropoietin, granulocyte colony-stimulating factor, or stem cell factor

The residual megakaryocyte and platelet production in c-Mpl–deficient mice is not dependent on the actions of interleukin-6, interleukin-11, or leukemia inhibitory factor

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American Society of Hematology

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ASH Publications

American Society of Hematology

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