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Journal Articles

Clinical Response to Azacitidine in Myelodysplastic Neoplasms Is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor Cells In Vivo

Julie A.I. Thoms, Feng Yan, Henry R. Hampton, Sarah Davidson, Swapna Joshi, Jesslyn Saw, Chowdhury H. Sarowar, Xin Ying Lim, Andrea C Nunez, Purvi M. Kakadia, Golam Sarower Bhuyan, Xiaoheng Zou, Mary Nguyen, Elaheh S Ghodousi, Forrest C Koch, Fatemeh Vafaee, I. Richard Thompson, Mohammad M. Karimi, Russell Pickford, Mark J Raftery, Sally Hough, Griselda Buckland, Michelle Bailey, Yuvaraj Ghodke, Noorul Absar, Lachlin Vaughan, Leonardo Pasalic, Chun Yew Fong, Melita Kenealy, Devendra Hiwase, Rohanna Stoddart, Soma Mohammed, Linda Lee, Freda H Passam, Stephen Robert Larsen, Kevin J Spring, Kristen K Skarratt, Patricia Rebeiro, Peter Presgrave, William S Stevenson, Silvia Ling, Campbell Tiley, Stephen Fuller, Fernando Roncolato, Anoop K Enjeti, Dirk Hoenemann, Charlotte Lemech, Christopher J Jolly, Stefan K. Bohlander, David J. Curtis, Jason Wong, Ashwin Unnikrishnan, Mark S. Hertzberg, Jake Olivier, Mark N Polizzotto, John E Pimanda

Blood (2024) 144 (Supplement 1): 3223.

https://doi.org/10.1182/blood-2024-201216

Published: 2024

Journal Articles

Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy

Blood (2023) 141 (11): 1316–1321.

https://doi.org/10.1182/blood.2022018602

Published: 2023

Includes: Supplemental data

Journal Articles

Clinical Response to Azacytidine (AZA) Is Associated with Increased Contribution from Mutated Blood Progenitors: Insights from Single Cell Genotyping of Matched Stem/Progenitor and Mature Blood Cells from MDS/CMML Patients Pre- and Post-AZA Treatment

Blood (2022) 140 (Supplement 1): 9751–9752.

https://doi.org/10.1182/blood-2022-163158

Published: 2022

Journal Articles

In Vivo Drug Incorporation and Intracellular Dynamics of Injectable Versus Oral Azacytidine: A Phase II Open Label Multicentre Trial

Blood (2022) 140 (Supplement 1): 6927–6929.

https://doi.org/10.1182/blood-2022-157634

Published: 2022

Journal Articles

Identification of Recurrent Alternative RNA Splicing in Adverse-Risk Acute Myeloid Leukemia

Govardhan Anande, Ashwin Unnikrishnan, PhD, Nandan Deshpande, PhD, Sylvain Mareschal, Aarif M. N. Batcha, Tobias Herold, MD, Sören Lehmann, MD PhD, Marc Wilkins, PhD, Jason Wong, PhD, John Pimanda, MBBS, PhD

Blood (2019) 134 (Supplement_1): 457.

https://doi.org/10.1182/blood-2019-129537

Published: 2019

Journal Articles

In Vivo Assessment of Intracellular Dynamics Comparing Injection Versus Oral Azacitidine in a Phase IIb Investigator Initiated Clinical Trial

Blood (2019) 134 (Supplement_1): 4247.

https://doi.org/10.1182/blood-2019-123921

Published: 2019

Journal Articles

Small-Molecule Inhibition of PRMT5 Induces Translational Stress and p53 in JAK2V617F Mutant Myeloproliferative Neoplasms

Stefan Sonderegger, PhD MSc, Loretta Cerruti, BSc, Cedric Tremblay, PhD, Emma Toulmin, PhD, Jesslyn Saw, BSc, Tom Nebl, PhD, Katherine M Hannan, PhD, Steven W. Lane, MD PhD, Hendrik Falk, PhD, Ashwin Unnikrishnan, PhD, Paul Stupple, PhD, Ian Street, PhD, Stephen Jane, MDPhD, Rachel Altura, PhD, Benjamin Nicholson, PhD, David J. Curtis, MBBS,PhD

Blood (2018) 132 (Supplement 1): 53.

https://doi.org/10.1182/blood-2018-99-118406

Published: 2018

Journal Articles

Srsf2 P95H initiates myeloid bias and myelodysplastic/myeloproliferative syndrome from hemopoietic stem cells

Monique F. Smeets, Shuh Ying Tan, Jane Jialu Xu, Govardhan Anande, Ashwin Unnikrishnan, Alistair M. Chalk, Scott R. Taylor, John E. Pimanda, Meaghan Wall, Louise E. Purton, Carl R. Walkley

Blood (2018) 132 (6): 608–621.

https://doi.org/10.1182/blood-2018-04-845602

Published: 2018

Includes: Supplemental data

Journal Articles

Granulomonocytic Progenitors (GMPs) Are Key Target Cells of Azacitidine in MDS and AML

Ashfaq Ali, PhD, Justine Penneroux, Reinaldo Dal Bello Jr, Aline Massé, Samuel Quentin, Ashwin Unnikrishnan, PhD, Lucie Hernandez, Emmanuel Raffoux, MD, Raouf Benabelali, Aline Renneville, MDPhD, Claude Preudhomme, PharmD, PhD, John Pimanda, PhDFRACP,FRCPA,MBBS, Herve Dombret, MD, Jean Soulier, MDPhD, Pierre Fenaux, MD PhD, Emmanuelle Clappier, PharmD,PhD, Lionel Ades, MD PhD, Raphael Itzykson, MD PhD

Blood (2017) 130 (Supplement 1): 587.

https://doi.org/10.1182/blood.V130.Suppl_1.587.587

Published: 2017

Journal Articles

Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes

Blood (2016) 128 (15): 1928–1939.

https://doi.org/10.1182/blood-2016-02-697870

Published: 2016

Includes: Supplemental data

Journal Articles

An Integrative Genomics Approach Uncovers the Basis of Resistance to AZA Therapy in MDS and CMML

Blood (2015) 126 (23): 710.

https://doi.org/10.1182/blood.V126.23.710.710

Published: 2015

Journal Articles

Identification of a Prognostic Gene Expression Signature for AZA Response in MDS and CMML Patients

Blood (2014) 124 (21): 4601.

https://doi.org/10.1182/blood.V124.21.4601.4601

Published: 2014

Journal Articles

Mutations in Histone Modulators and HOXA5 Methylation Levels Affects Survival in Azacitidine Treated MDS Patients

Magnus Tobiasson, MD, Mohsen Karimi, Marios Dimitriou, Ying Qu, MDM.Sc, Andreas Lennartsson, PhD, Hani Abdulkadir Ali, Ashwin Unnikrishnan, PhD, Martin Jadersten, MDPhD, Monika Jansson, Asmaa Ben Azenkoud, John E Pimanda, MD PhD, Karl Ekwall, Prof, Johanna Ungerstedt, MD PhD, Soren Lehmann, MD PhD, Eva Hellstrom-Lindberg, MD PhD

Blood (2014) 124 (21): 4613.

https://doi.org/10.1182/blood.V124.21.4613.4613

Published: 2014

Journal Articles

Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes

Dominik Beck, Julie A. I. Thoms, Dilmi Perera, Judith Schütte, Ashwin Unnikrishnan, Kathy Knezevic, Sarah J. Kinston, Nicola K. Wilson, Tracey A. O’Brien, Berthold Göttgens, Jason W. H. Wong, John E. Pimanda

Blood (2013) 122 (14): e12–e22.

https://doi.org/10.1182/blood-2013-03-490425

Published: 2013

Includes: Supplemental data

NARROW

Clinical Response to Azacitidine in Myelodysplastic Neoplasms Is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor Cells In Vivo

Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy

Clinical Response to Azacytidine (AZA) Is Associated with Increased Contribution from Mutated Blood Progenitors: Insights from Single Cell Genotyping of Matched Stem/Progenitor and Mature Blood Cells from MDS/CMML Patients Pre- and Post-AZA Treatment

In Vivo Drug Incorporation and Intracellular Dynamics of Injectable Versus Oral Azacytidine: A Phase II Open Label Multicentre Trial

Identification of Recurrent Alternative RNA Splicing in Adverse-Risk Acute Myeloid Leukemia

In Vivo Assessment of Intracellular Dynamics Comparing Injection Versus Oral Azacitidine in a Phase IIb Investigator Initiated Clinical Trial

Small-Molecule Inhibition of PRMT5 Induces Translational Stress and p53 in JAK2V617F Mutant Myeloproliferative Neoplasms

Srsf2 P95H initiates myeloid bias and myelodysplastic/myeloproliferative syndrome from hemopoietic stem cells

Granulomonocytic Progenitors (GMPs) Are Key Target Cells of Azacitidine in MDS and AML

Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes

An Integrative Genomics Approach Uncovers the Basis of Resistance to AZA Therapy in MDS and CMML

Identification of a Prognostic Gene Expression Signature for AZA Response in MDS and CMML Patients

Mutations in Histone Modulators and HOXA5 Methylation Levels Affects Survival in Azacitidine Treated MDS Patients

Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes

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American Society of Hematology

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ASH Publications

American Society of Hematology

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