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Journal Articles

A Novel in Vitro Model of Pre-Leukemic Competition Reveals “Super-Competitive” TET2-Mutant Hematopoietic Stem Cell Clones

Lilia Cabrera-Cosme, Juan Rubio-Lara, Ellie Bennett, Joanna Milek, Maria Jassinskaja, Sandy MacDonald, Karen Hogg, Nicola K. Wilson, Berthold Gottgens, David Kent
Journal: Blood
Blood (2024) 144 (Supplement 1): 4115.
https://doi.org/10.1182/blood-2024-207127
Published: 2024
Journal Articles

Life History of Normal Human Lymphocytes Revealed By Somatic Mutations

Heather E Machado, PhD, Nina Friesgaard Øbro, Emily Mitchell, Megan Davies, Anthony R Green, Kourosh Saeb-Parsy, Daniel James Hodson, MD PhD, David Kent, PhD, Peter J Campbell
Journal: Blood
Blood (2019) 134 (Supplement_1): 1045.
https://doi.org/10.1182/blood-2019-128188
Published: 2019
Journal Articles

Niche Heterogeneity Impacts Evolution of Myeloproliferative Neoplasms Driven By the Same Oncogenic Pathway

Claudia Korn, PhD, Justyna Rak, PhD, Andrés García-García, PhD, Claire Fielding, Reema Khorshed, PhD, Sara González-Antón, Juan Li, PhD, Ruggiero Norfo, PhD, E Joanna Baxter, PhD, Thomas McKerrell, MD PhD, Thomas Roberts, Hesham Eldaly, MD, Anna L Godfrey, PhD, Aracely Castillo-Venzor, Anjali Kusumbe, PhD, Adam J. Mead, MD PhD, Anthony R Green, David Kent, PhD, Cristina Lo Celso, PhD, Simon Mendez-Ferrer, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 98.
https://doi.org/10.1182/blood-2018-99-113495
Published: 2018
Journal Articles

Three Cases of Patients with Complement Regulatory Factor Genetic Mutations and Acquired Thrombotic Thrombocytopenic Purpura (TTP)

Shebli Atrash, MD, David Kent McKelvey, MD, Appalanaidu Sasapu, MD MS, Muthu Veeraputhiran, MD MPH, Soumya Pandey, MD, Michele H. Cottler-Fox, MD, Pooja Motwani, MD
Journal: Blood
Blood (2016) 128 (22): 1362.
https://doi.org/10.1182/blood.V128.22.1362.1362
Published: 2016
Journal Articles

Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes

Rabab Nasrallah, Eva M. Fast, Parham Solaimani, Kathy Knezevic, Alexia Eliades, Rahima Patel, Roshana Thambyrajah, Ashwin Unnikrishnan, Julie Thoms, Dominik Beck, Chris S. Vink, Aileen Smith, Jason Wong, Mairi Shepherd, David Kent, Rahul Roychoudhuri, Fabian Paul, Julia Klippert, Annette Hammes, Thomas Willnow, Bertie Göttgens, Elaine Dzierzak, Leonard I. Zon, George Lacaud, Valerie Kouskoff, John E. Pimanda
Journal: Blood
Blood (2016) 128 (15): 1928–1939.
https://doi.org/10.1182/blood-2016-02-697870
Published: 2016
Includes: Supplemental data
Journal Articles

Sf3b1 K700E Mutation Impairs Pre-mRNA Splicing and Definitive Hematopoiesis in a Conditional Knock-in Mouse Model

Annalisa Mupo, PhD, Vijitha Sathiaseelan, Michael Seiler, PhD, David Kent, PhD, Shouyong Peng, PhD, Ruben Bautista, Suruchi Pacharne, Barry Rosen, Manousos Koutsourakis, Nicla Manes, Frances Law, Elli Papaemmanuil, PhD, Silvia Buonamici, PhD, Peter J Campbell, MD PhD, Niccolo Bolli, MD PhD, George S. Vassiliou, MD PhD
Journal: Blood
Blood (2015) 126 (23): 140.
https://doi.org/10.1182/blood.V126.23.140.140
Published: 2015
Journal Articles

Stromal Cell Regulation of Murine Hematopoietic Stem Cells.

Stefan Wohrer, MD, Keegan Rowe, Heidi Mader, Claudia Benz, PhD, Michael R Copley, David Kent, PhD, Robert A.J. Oostendorp, BSc, MSc, PhD, Connie J. Eaves, PhD
Journal: Blood
Blood (2010) 116 (21): 1566.
https://doi.org/10.1182/blood.V116.21.1566.1566
Published: 2010
Journal Articles

The Reduced Lymphopoietic Potential of a Novel Subclass of Hematopoietic Stem Cells Is Mediated by Specific Defects In the Production and Activity of Their Common Lymphoid Progenitor (CLP) Progeny

Claudia Benz, Michael R Copley, David Kent, Stefan Woehrer, MD, Keegan Rowe, Connie J. Eaves, PhD
Journal: Blood
Blood (2010) 116 (21): 576.
https://doi.org/10.1182/blood.V116.21.576.576
Published: 2010
Journal Articles

Differences in the Transcriptomes of Highly Purified Fetal Liver and Adult Bone Marrow Hematopoietic Stem Cells Revealed by Long Serial Analysis of Gene Expression (LongSAGE)

David Kent, Yun Zhao, Ph.D., Michelle Bowie, Ph.D., Brad Dykstra, Ph.D., Jay Cheyne, B.Sc., Yongjun Zhao, Allen Delaney, Martin Hirst, Marco Marra, Ph.D., Connie J. Eaves, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 1277.
https://doi.org/10.1182/blood.V110.11.1277.1277
Published: 2007
Journal Articles

Unexpected and Sustained Symmetry in the Repopulation Programs Displayed by Clonally Amplified Hematopoietic Stem Cells.

Brad Dykstra, David Kent, Melisa Hamilton, Merete Kristiansen, Kristin Lyons, Lindsay McCaffrey, Shannon Russell, Connie J. Eaves, PhD
Journal: Blood
Blood (2006) 108 (11): 1651.
https://doi.org/10.1182/blood.V108.11.1651.1651
Published: 2006
Journal Articles

High Resolution Time-Lapse Monitoring of Individual Hematopoietic Stem Cells Reveals New Biomarkers of Self-Renewal.

Brad Dykstra, John Ramunas, David Kent, Lindsay McCaffrey, Erin Szumsky, Liam Kelly, Kristin Farn, Connie Eaves, Eric Jervis
Journal: Blood
Blood (2005) 106 (11): 795.
https://doi.org/10.1182/blood.V106.11.795.795
Published: 2005
Journal Articles

New Fine Structure within the Adult Hematopoietic Stem Cell Compartment Revealed by Longterm Analysis of Mice Repopulated with Single Cells or Their In Vitro Generated Clonal Progeny.

Brad Dykstra, David Kent, Lindsay McCaffrey, Kristin Lyons, Merete Kristiansen, Melisa Hamilton, Connie Eaves
Journal: Blood
Blood (2005) 106 (11): 1720.
https://doi.org/10.1182/blood.V106.11.1720.1720
Published: 2005