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Journal Articles

A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML

Blood (2021) 137 (24): 3403–3415.

https://doi.org/10.1182/blood.2020009023

Published: 2021

Includes: Supplemental data

Journal Articles

Sorafenib treatment of FLT3-ITD + acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation

Cheuk Him Man, Tsz Kan Fung, Christa Ho, Heron H. C. Han, Howard C. H. Chow, Alvin C. H. Ma, William W. L. Choi, Si Lok, Alice M. S. Cheung, Connie Eaves, Yok Lam Kwong, Anskar Y. H. Leung

Blood (2012) 119 (22): 5133–5143.

https://doi.org/10.1182/blood-2011-06-363960

Published: 2012

Includes: Supplemental data

Journal Articles

Properties of CD34 + CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate

Xiaoyan Jiang, Donna Forrest, Franck Nicolini, Ali Turhan, Joelle Guilhot, Calvin Yip, Tessa Holyoake, Heather Jorgensen, Karen Lambie, Kyi Min Saw, Emily Pang, Ranko Vukovic, Paeta Lehn, Ashley Ringrose, Miao Yu, Ryan R. Brinkman, Clay Smith, Allen Eaves, Connie Eaves

Blood (2010) 116 (12): 2112–2121.

https://doi.org/10.1182/blood-2009-05-222471

Published: 2010

Includes: Supplemental data

Journal Articles

Properties of CD34 + CML Cells That Predict Clinical Response to Tyrosine Kinase Inhibitors.

Xiaoyan Jiang, MD, PhD, Donna Forrest, MD, Franck Nicolini, MD, PhD, Karen Lambie, Kyi Min Saw, Emily Pang, Ranko Vukovic, Clayton Smith, MD, Allen Eaves, MD, PhD, Connie Eaves, PhD

Blood (2007) 110 (11): 324.

https://doi.org/10.1182/blood.V110.11.324.324

Published: 2007

Journal Articles

Chronic Myeloid Leukemia Stem Cells Possess Unique Properties That Predict Intrinsic and Acquired Resistance to Imatinib Mesylate.

Xiaoyan Jiang, MD, PhD, Yun Zhao, PhD, Clayton Smith, MD, Maura Gasparetto, MD, Kyi Min Saw, Ali Turhan, MD, PhD, Allen Eaves, MD, PhD, Connie Eaves, PhD

Blood (2006) 108 (11): 752.

https://doi.org/10.1182/blood.V108.11.752.752

Published: 2006

Journal Articles

Leukemic Stem Cells of Chronic Phase CML Patients Possess Uniquely Elevated BCR-ABL Kinase Activity and Acquire Spontaneous BCR-ABL Kinase Domain Mutations at a High Frequency.

Xiaoyan Jiang, MD, PhD, Kyi Min Saw, Allen Eaves, MD, PhD, Connie Eaves, PhD

Blood (2005) 106 (11): 438.

https://doi.org/10.1182/blood.V106.11.438.438

Published: 2005

Journal Articles

High Resolution Time-Lapse Monitoring of Individual Hematopoietic Stem Cells Reveals New Biomarkers of Self-Renewal.

Brad Dykstra, John Ramunas, David Kent, Lindsay McCaffrey, Erin Szumsky, Liam Kelly, Kristin Farn, Connie Eaves, Eric Jervis

Blood (2005) 106 (11): 795.

https://doi.org/10.1182/blood.V106.11.795.795

Published: 2005

Journal Articles

New Fine Structure within the Adult Hematopoietic Stem Cell Compartment Revealed by Longterm Analysis of Mice Repopulated with Single Cells or Their In Vitro Generated Clonal Progeny.

Brad Dykstra, David Kent, Lindsay McCaffrey, Kristin Lyons, Merete Kristiansen, Melisa Hamilton, Connie Eaves

Blood (2005) 106 (11): 1720.

https://doi.org/10.1182/blood.V106.11.1720.1720

Published: 2005

Journal Articles

Leukemic Stem Cells of Chronic Phase CML Patients Consistently Display Very High BCR-ABL Transcript Levels and Reduced Responsiveness to Imatinib Mesylate in Addition to Generating a Rare Subset That Produce Imatinib Mesylate-Resistant Differentiated Progeny.

Xiaoyan Jiang, MD, PhD, Yun Zhao, PhD, Wing Yiu Chan, Emily Pang, Allen Eaves, MD, PhD, Connie Eaves, PhD.

Blood (2004) 104 (11): 711.

https://doi.org/10.1182/blood.V104.11.711.711

Published: 2004

Journal Articles

ABC transporter activities of murine hematopoietic stem cells vary according to their developmental and activation status

Naoyuki Uchida, Brad Dykstra, Kristin Lyons, Frank Leung, Merete Kristiansen, Connie Eaves

Blood (2004) 103 (12): 4487–4495.

https://doi.org/10.1182/blood-2003-11-3989

Published: 2004

Journal Articles

Engraftment of NOD/SCID-β2 microglobulin null mice with multilineage neoplastic cells from patients with myelodysplastic syndrome

Eleni Thanopoulou, Johanne Cashman, Theodora Kakagianne, Allen Eaves, Nicholas Zoumbos, Connie Eaves

Blood (2004) 103 (11): 4285–4293.

https://doi.org/10.1182/blood-2003-09-3192

Published: 2004

Journal Articles

Deregulated expression in Ph + human leukemias of AHI-1 , a gene activated by insertional mutagenesis in mouse models of leukemia

Xiaoyan Jiang, Yun Zhao, Wing-Yiu Chan, Suzanne Vercauteren, Emily Pang, Sean Kennedy, Frank Nicolini, Allen Eaves, Connie Eaves

Blood (2004) 103 (10): 3897–3904.

https://doi.org/10.1182/blood-2003-11-4026

Published: 2004

Journal Articles

Evidence for a positive role of SHIP in the BCR-ABL–mediated transformation of primitive murine hematopoietic cells and in human chronic myeloid leukemia

Xiaoyan Jiang, Matthew Stuible, Yves Chalandon, Andra Li, Wing Yiu Chan, Wolfgang Eisterer, Gerald Krystal, Allen Eaves, Connie Eaves

Blood (2003) 102 (8): 2976–2984.

https://doi.org/10.1182/blood-2003-05-1550

Published: 2003

Journal Articles

Modulation of p210 BCR-ABL activity in transduced primary human hematopoietic cells controls lineage programming

Yves Chalandon, Xiaoyan Jiang, Glen Hazlewood, Slade Loutet, Eibhlin Conneally, Allen Eaves, Connie Eaves

Blood (2002) 99 (9): 3197–3204.

https://doi.org/10.1182/blood.V99.9.3197

Published: 2002

Journal Articles

Ex vivo treatment of proliferating human cord blood stem cells with stroma-derived factor–1 enhances their ability to engraft NOD/SCID mice

Hanno Glimm, Patrick Tang, Ian Clark-Lewis, Christof von Kalle, Connie Eaves

Blood (2002) 99 (9): 3454–3457.

https://doi.org/10.1182/blood.V99.9.3454

Published: 2002

Journal Articles

Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD/SCID mice

Johanne Cashman, Ian Clark-Lewis, Allen Eaves, Connie Eaves

Blood (2002) 99 (3): 792–799.

https://doi.org/10.1182/blood.V99.3.792

Published: 2002

Journal Articles

Isolation of a Highly Quiescent Subpopulation of Primitive Leukemic Cells in Chronic Myeloid Leukemia

Tessa Holyoake, Xiaoyan Jiang, Connie Eaves, Allen Eaves

Blood (1999) 94 (6): 2056–2064.

https://doi.org/10.1182/blood.V94.6.2056

Published: 1999

Journal Articles

Diphtheria Toxin Fused to Granulocyte-Macrophage Colony-Stimulating Factor Is Toxic to Blasts From Patients With Juvenile Myelomonocytic Leukemia and Chronic Myelomonocytic Leukemia

Arthur E. Frankel, Michael Lilly, Robert Kreitman, Donna Hogge, Miloslav Beran, Melvin H. Freedman, Peter D. Emanuel, Chris McLain, Philip Hall, Edward Tagge, Marc Berger, Connie Eaves

Blood (1998) 92 (11): 4279–4286.

https://doi.org/10.1182/blood.V92.11.4279

Published: 1998

NARROW

A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML

Sorafenib treatment of FLT3-ITD + acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation

Properties of CD34 + CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate

Properties of CD34 + CML Cells That Predict Clinical Response to Tyrosine Kinase Inhibitors.

Chronic Myeloid Leukemia Stem Cells Possess Unique Properties That Predict Intrinsic and Acquired Resistance to Imatinib Mesylate.

Leukemic Stem Cells of Chronic Phase CML Patients Possess Uniquely Elevated BCR-ABL Kinase Activity and Acquire Spontaneous BCR-ABL Kinase Domain Mutations at a High Frequency.

High Resolution Time-Lapse Monitoring of Individual Hematopoietic Stem Cells Reveals New Biomarkers of Self-Renewal.

New Fine Structure within the Adult Hematopoietic Stem Cell Compartment Revealed by Longterm Analysis of Mice Repopulated with Single Cells or Their In Vitro Generated Clonal Progeny.

Leukemic Stem Cells of Chronic Phase CML Patients Consistently Display Very High BCR-ABL Transcript Levels and Reduced Responsiveness to Imatinib Mesylate in Addition to Generating a Rare Subset That Produce Imatinib Mesylate-Resistant Differentiated Progeny.

ABC transporter activities of murine hematopoietic stem cells vary according to their developmental and activation status

Engraftment of NOD/SCID-β2 microglobulin null mice with multilineage neoplastic cells from patients with myelodysplastic syndrome

Deregulated expression in Ph + human leukemias of AHI-1 , a gene activated by insertional mutagenesis in mouse models of leukemia

Evidence for a positive role of SHIP in the BCR-ABL–mediated transformation of primitive murine hematopoietic cells and in human chronic myeloid leukemia

Modulation of p210 BCR-ABL activity in transduced primary human hematopoietic cells controls lineage programming

Ex vivo treatment of proliferating human cord blood stem cells with stroma-derived factor–1 enhances their ability to engraft NOD/SCID mice

Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD/SCID mice

Isolation of a Highly Quiescent Subpopulation of Primitive Leukemic Cells in Chronic Myeloid Leukemia

Diphtheria Toxin Fused to Granulocyte-Macrophage Colony-Stimulating Factor Is Toxic to Blasts From Patients With Juvenile Myelomonocytic Leukemia and Chronic Myelomonocytic Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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