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Journal Articles

Properties of CD34 + CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate

Xiaoyan Jiang, Donna Forrest, Franck Nicolini, Ali Turhan, Joelle Guilhot, Calvin Yip, Tessa Holyoake, Heather Jorgensen, Karen Lambie, Kyi Min Saw, Emily Pang, Ranko Vukovic, Paeta Lehn, Ashley Ringrose, Miao Yu, Ryan R. Brinkman, Clay Smith, Allen Eaves, Connie Eaves

Blood (2010) 116 (12): 2112–2121.

https://doi.org/10.1182/blood-2009-05-222471

Published: 2010

Includes: Supplemental data

Journal Articles

Properties of CD34 + CML Cells That Predict Clinical Response to Tyrosine Kinase Inhibitors.

Xiaoyan Jiang, MD, PhD, Donna Forrest, MD, Franck Nicolini, MD, PhD, Karen Lambie, Kyi Min Saw, Emily Pang, Ranko Vukovic, Clayton Smith, MD, Allen Eaves, MD, PhD, Connie Eaves, PhD

Blood (2007) 110 (11): 324.

https://doi.org/10.1182/blood.V110.11.324.324

Published: 2007

Journal Articles

Chronic Myeloid Leukemia Stem Cells Possess Unique Properties That Predict Intrinsic and Acquired Resistance to Imatinib Mesylate.

Xiaoyan Jiang, MD, PhD, Yun Zhao, PhD, Clayton Smith, MD, Maura Gasparetto, MD, Kyi Min Saw, Ali Turhan, MD, PhD, Allen Eaves, MD, PhD, Connie Eaves, PhD

Blood (2006) 108 (11): 752.

https://doi.org/10.1182/blood.V108.11.752.752

Published: 2006

Journal Articles

Leukemic Stem Cells of Chronic Phase CML Patients Possess Uniquely Elevated BCR-ABL Kinase Activity and Acquire Spontaneous BCR-ABL Kinase Domain Mutations at a High Frequency.

Xiaoyan Jiang, MD, PhD, Kyi Min Saw, Allen Eaves, MD, PhD, Connie Eaves, PhD

Blood (2005) 106 (11): 438.

https://doi.org/10.1182/blood.V106.11.438.438

Published: 2005

Journal Articles

Leukemic Stem Cells of Chronic Phase CML Patients Consistently Display Very High BCR-ABL Transcript Levels and Reduced Responsiveness to Imatinib Mesylate in Addition to Generating a Rare Subset That Produce Imatinib Mesylate-Resistant Differentiated Progeny.

Xiaoyan Jiang, MD, PhD, Yun Zhao, PhD, Wing Yiu Chan, Emily Pang, Allen Eaves, MD, PhD, Connie Eaves, PhD.

Blood (2004) 104 (11): 711.

https://doi.org/10.1182/blood.V104.11.711.711

Published: 2004

Journal Articles

Engraftment of NOD/SCID-β2 microglobulin null mice with multilineage neoplastic cells from patients with myelodysplastic syndrome

Eleni Thanopoulou, Johanne Cashman, Theodora Kakagianne, Allen Eaves, Nicholas Zoumbos, Connie Eaves

Blood (2004) 103 (11): 4285–4293.

https://doi.org/10.1182/blood-2003-09-3192

Published: 2004

Journal Articles

Deregulated expression in Ph + human leukemias of AHI-1 , a gene activated by insertional mutagenesis in mouse models of leukemia

Xiaoyan Jiang, Yun Zhao, Wing-Yiu Chan, Suzanne Vercauteren, Emily Pang, Sean Kennedy, Frank Nicolini, Allen Eaves, Connie Eaves

Blood (2004) 103 (10): 3897–3904.

https://doi.org/10.1182/blood-2003-11-4026

Published: 2004

Journal Articles

Evidence for a positive role of SHIP in the BCR-ABL–mediated transformation of primitive murine hematopoietic cells and in human chronic myeloid leukemia

Xiaoyan Jiang, Matthew Stuible, Yves Chalandon, Andra Li, Wing Yiu Chan, Wolfgang Eisterer, Gerald Krystal, Allen Eaves, Connie Eaves

Blood (2003) 102 (8): 2976–2984.

https://doi.org/10.1182/blood-2003-05-1550

Published: 2003

Journal Articles

Primitive interleukin 3 null hematopoietic cells transduced with BCR-ABL show accelerated loss after culture of factor-independence in vitro and leukemogenic activity in vivo

Xiaoyan Jiang, Eddy Ng, Calvin Yip, Wolfgang Eisterer, Yves Chalandon, Matthew Stuible, Allen Eaves, Connie J. Eaves

Blood (2002) 100 (10): 3731–3740.

https://doi.org/10.1182/blood-2002-05-1324

Published: 2002

Journal Articles

Modulation of p210 BCR-ABL activity in transduced primary human hematopoietic cells controls lineage programming

Yves Chalandon, Xiaoyan Jiang, Glen Hazlewood, Slade Loutet, Eibhlin Conneally, Allen Eaves, Connie Eaves

Blood (2002) 99 (9): 3197–3204.

https://doi.org/10.1182/blood.V99.9.3197

Published: 2002

Journal Articles

Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD/SCID mice

Johanne Cashman, Ian Clark-Lewis, Allen Eaves, Connie Eaves

Blood (2002) 99 (3): 792–799.

https://doi.org/10.1182/blood.V99.3.792

Published: 2002

Journal Articles

Isolation of a Highly Quiescent Subpopulation of Primitive Leukemic Cells in Chronic Myeloid Leukemia

Tessa Holyoake, Xiaoyan Jiang, Connie Eaves, Allen Eaves

Blood (1999) 94 (6): 2056–2064.

https://doi.org/10.1182/blood.V94.6.2056

Published: 1999

NARROW

Properties of CD34 + CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate

Properties of CD34 + CML Cells That Predict Clinical Response to Tyrosine Kinase Inhibitors.

Chronic Myeloid Leukemia Stem Cells Possess Unique Properties That Predict Intrinsic and Acquired Resistance to Imatinib Mesylate.

Leukemic Stem Cells of Chronic Phase CML Patients Possess Uniquely Elevated BCR-ABL Kinase Activity and Acquire Spontaneous BCR-ABL Kinase Domain Mutations at a High Frequency.

Leukemic Stem Cells of Chronic Phase CML Patients Consistently Display Very High BCR-ABL Transcript Levels and Reduced Responsiveness to Imatinib Mesylate in Addition to Generating a Rare Subset That Produce Imatinib Mesylate-Resistant Differentiated Progeny.

Engraftment of NOD/SCID-β2 microglobulin null mice with multilineage neoplastic cells from patients with myelodysplastic syndrome

Deregulated expression in Ph + human leukemias of AHI-1 , a gene activated by insertional mutagenesis in mouse models of leukemia

Evidence for a positive role of SHIP in the BCR-ABL–mediated transformation of primitive murine hematopoietic cells and in human chronic myeloid leukemia

Primitive interleukin 3 null hematopoietic cells transduced with BCR-ABL show accelerated loss after culture of factor-independence in vitro and leukemogenic activity in vivo

Modulation of p210 BCR-ABL activity in transduced primary human hematopoietic cells controls lineage programming

Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD/SCID mice

Isolation of a Highly Quiescent Subpopulation of Primitive Leukemic Cells in Chronic Myeloid Leukemia

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American Society of Hematology

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American Society of Hematology

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