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Journal Articles

Targeting AXL kinase sensitizes leukemic stem and progenitor cells to venetoclax treatment in acute myeloid leukemia

Blood (2021) 137 (26): 3641–3655.

https://doi.org/10.1182/blood.2020007651

Published: 2021

Includes: Supplemental data

Journal Articles

Targeting AXL Kinase Sensitizes Acute Myeloid Leukemia Stem and Progenitor Cells to Venetoclax Treatment

Katharina Rothe, PhD, Xiaojia Niu, PhD, Min Chen, PhD, Rick Li, Sungeun Nam, Xiuyan Zhang, German Novakovskiy, Yehyeon Ahn, Shenshen Lai, Hong Zhang, PhD, Jun Yan, Hong Liu, Yun Zhao, PhD, Depei Wu, MDPhD, Yubin Ge, PhD, Wyeth W. Wasserman, Calvin K. Yip, Zaihui Zhang, PhD, Xiaoyan Jiang, MD PhD

Blood (2020) 136 (Supplement 1): 20.

https://doi.org/10.1182/blood-2020-140595

Published: 2020

Journal Articles

Growth Arrest-Specific 2 Promotes the Growth of T-Cell Acute Lymphoblastic Leukemia Cells Via Its Regulation of CXCR4

Wenjuan Ma, Yan Wan, Haixia Zhou, MD PhD, Li Zhu, MD PhD, Yun Zhao, PhD

Blood (2018) 132 (Supplement 1): 4081.

https://doi.org/10.1182/blood-2018-99-114354

Published: 2018

Journal Articles

Zinc Finger Protein X-Linked Exhibits Pro-Leukemia Activity Via WNT3 in Chronic Myeloid Leukemia Stem/Progenitor Cells

Xiuyan Zhang, Yu Wang, Lun Xiao, Haixia Zhou, MD PhD, Li Zhu, MD PhD, Yun Zhao, PhD

Blood (2018) 132 (Supplement 1): 4247.

https://doi.org/10.1182/blood-2018-99-114663

Published: 2018

Journal Articles

Oncogenic Heterogeneous Nuclear Ribonucleoprotein D-like Promotes the Growth of Chronic Myeloid Leukemia Cells through Post-Transcriptional Regulation of Pre-B-Cell Leukemia Homeobox 1

Dehuan Ji, Pengshan Zhang, Wenjuan Ma, Xiuyan Zhang, Haixia Zhou, MD PhD, Yun Zhao, PhD, Li Zhu, MD PhD

Blood (2017) 130 (Supplement 1): 4174.

https://doi.org/10.1182/blood.V130.Suppl_1.4174.4174

Published: 2017

Journal Articles

SATB1 overexpression promotes malignant T-cell proliferation in cutaneous CD30 + lymphoproliferative disease by repressing p21

Yang Wang, Xiaoguang Gu, Gaolei Zhang, Lin Wang, Tingting Wang, Yun Zhao, Xiuyan Zhang, Youwen Zhou, Marshall Kadin, Ping Tu

Blood (2014) 123 (22): 3452–3461.

https://doi.org/10.1182/blood-2013-10-534693

Published: 2014

Includes: Supplemental data

Journal Articles

A Novel TWIST2-ID2 Axis That Modulates The Growth and Imatinib Sensitivity Of CML CD34+ Cells

Yun Zhao, PhD, Wenjuan Ma, Xiuyan Zhang, Jiangxia Cui, Ivan Sloma, PhD, Haixia Zhou, Depei Wu, MD, Connie J Eaves, PhD

Blood (2013) 122 (21): 511.

https://doi.org/10.1182/blood.V122.21.511.511

Published: 2013

Journal Articles

TWIST2 Was Deregulated In Human Acute Myeloid Leukemia and Might Play a Tumor Suppressor Role

Yun Zhao, PhD, Xiuyan Zhang, Yongjin Zhu, MD, Jiangxia Cui, Lidong Shan, MD, Hong Yao, Xiaosu Zhu, Li Zhu, MD, PhD

Blood (2010) 116 (21): 3141.

https://doi.org/10.1182/blood.V116.21.3141.3141

Published: 2010

Journal Articles

The Potential Role of Galectin-1 in Hypoxia Induced AML Cell Differentiation through C/EBPαa Transcription Regulation.

Meng Zhao, Xu-Yun Zhao, Shi-Hua Liao, Ke-Wen Zhao, Li-Shun Wang, Guo-Qiang Chen

Blood (2009) 114 (22): 3120.

https://doi.org/10.1182/blood.V114.22.3120.3120

Published: 2009

Journal Articles

Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential

David G. Kent, Michael R. Copley, Claudia Benz, Stefan Wöhrer, Brad J. Dykstra, Elaine Ma, John Cheyne, Yongjun Zhao, Michelle B. Bowie, Yun Zhao, Maura Gasparetto, Allen Delaney, Clayton Smith, Marco Marra, Connie J. Eaves

Blood (2009) 113 (25): 6342–6350.

https://doi.org/10.1182/blood-2008-12-192054

Published: 2009

Includes: Supplemental data

Journal Articles

Identification of AHI-1 Involvement in Mediating Cellular Resistance to Imatinib Mesylate in Chronic Myeloid Leukemia Cells

Donna DeGeer, Leon Zhou, Min Chen, MD, PhD, Yun Zhao, Ali G Turhan, M.D., PhD, Xiaoyan Jiang, MD, PhD

Blood (2008) 112 (11): 3201.

https://doi.org/10.1182/blood.V112.11.3201.3201

Published: 2008

Journal Articles

A Novel Strategy for Expanding Primitive Leukemic Cells from Chronic Phase CML Patients by Forced Overexpression of a NUP98-HOXA10 Homeodomain Fusion Gene.

Ivan Sloma, PhD, Suzan Imren, MD, Yun Zhao, PhD, Keith Humphries, MD, PhD, Connie J. Eaves, PhD

Blood (2008) 112 (11): 1078.

https://doi.org/10.1182/blood.V112.11.1078.1078

Published: 2008

Journal Articles

Differentially Expressed and Novel Transcripts in Highly Purified Chronic Phase CML Stem Cells

Yun Zhao, Allen Delaney, Afshin Raouf, Kamini Raghuram, Haiyan I Li, Angelique Schnerch, Xiaoyan Jiang, MD, PhD, Allen C Eaves, Marco A Marra, PhD, Connie J. Eaves, PhD

Blood (2008) 112 (11): 193.

https://doi.org/10.1182/blood.V112.11.193.193

Published: 2008

Journal Articles

Interaction of a Novel Signaling Protein (AHI-1) with BCR-ABL Modulates BCR-ABL Transforming Activity and Imatinib Response of Chronic Myeloid Leukemia Progenitor Cells.

Yun Zhao, PhD, Leon Zhou, MS, Ashley Ringrose, BS, Ann E.-J. Lin, BS, Erin Kennah, MS, Guoqing Sheng, PhD, Xiao-Jiang Li, PhD, Ali Turhan, PhD, Xiaoyan Jiang, MD, PhD

Blood (2007) 110 (11): 467.

https://doi.org/10.1182/blood.V110.11.467.467

Published: 2007

Journal Articles

Comparative Transcriptome Analysis of Different Subsets of CD34 + Normal and Chronic Myeloid Leukemia Cells Identifies Novel Perturbations in the CML Stem Cell Population.

Yun Zhao, PhD, Allen Delaney, PhD, Marco A. Marra, PhD, Xiaoyan Jiang, MD, PhD, Allen C. Eaves, MD, PhD, Connie J. Eaves, PhD

Blood (2007) 110 (11): 35.

https://doi.org/10.1182/blood.V110.11.35.35

Published: 2007

Journal Articles

Differences in the Transcriptomes of Highly Purified Fetal Liver and Adult Bone Marrow Hematopoietic Stem Cells Revealed by Long Serial Analysis of Gene Expression (LongSAGE)

David Kent, Yun Zhao, Ph.D., Michelle Bowie, Ph.D., Brad Dykstra, Ph.D., Jay Cheyne, B.Sc., Yongjun Zhao, Allen Delaney, Martin Hirst, Marco Marra, Ph.D., Connie J. Eaves, Ph.D.

Blood (2007) 110 (11): 1277.

https://doi.org/10.1182/blood.V110.11.1277.1277

Published: 2007

Journal Articles

Chronic Myeloid Leukemia Stem Cells Possess Unique Properties That Predict Intrinsic and Acquired Resistance to Imatinib Mesylate.

Xiaoyan Jiang, MD, PhD, Yun Zhao, PhD, Clayton Smith, MD, Maura Gasparetto, MD, Kyi Min Saw, Ali Turhan, MD, PhD, Allen Eaves, MD, PhD, Connie Eaves, PhD

Blood (2006) 108 (11): 752.

https://doi.org/10.1182/blood.V108.11.752.752

Published: 2006

Journal Articles

Leukemic Stem Cells of Chronic Phase CML Patients Consistently Display Very High BCR-ABL Transcript Levels and Reduced Responsiveness to Imatinib Mesylate in Addition to Generating a Rare Subset That Produce Imatinib Mesylate-Resistant Differentiated Progeny.

Xiaoyan Jiang, MD, PhD, Yun Zhao, PhD, Wing Yiu Chan, Emily Pang, Allen Eaves, MD, PhD, Connie Eaves, PhD.

Blood (2004) 104 (11): 711.

https://doi.org/10.1182/blood.V104.11.711.711

Published: 2004

Journal Articles

Deregulated expression in Ph + human leukemias of AHI-1 , a gene activated by insertional mutagenesis in mouse models of leukemia

Xiaoyan Jiang, Yun Zhao, Wing-Yiu Chan, Suzanne Vercauteren, Emily Pang, Sean Kennedy, Frank Nicolini, Allen Eaves, Connie Eaves

Blood (2004) 103 (10): 3897–3904.

https://doi.org/10.1182/blood-2003-11-4026

Published: 2004

NARROW

Targeting AXL kinase sensitizes leukemic stem and progenitor cells to venetoclax treatment in acute myeloid leukemia

Targeting AXL Kinase Sensitizes Acute Myeloid Leukemia Stem and Progenitor Cells to Venetoclax Treatment

Growth Arrest-Specific 2 Promotes the Growth of T-Cell Acute Lymphoblastic Leukemia Cells Via Its Regulation of CXCR4

Zinc Finger Protein X-Linked Exhibits Pro-Leukemia Activity Via WNT3 in Chronic Myeloid Leukemia Stem/Progenitor Cells

Oncogenic Heterogeneous Nuclear Ribonucleoprotein D-like Promotes the Growth of Chronic Myeloid Leukemia Cells through Post-Transcriptional Regulation of Pre-B-Cell Leukemia Homeobox 1

SATB1 overexpression promotes malignant T-cell proliferation in cutaneous CD30 + lymphoproliferative disease by repressing p21

A Novel TWIST2-ID2 Axis That Modulates The Growth and Imatinib Sensitivity Of CML CD34+ Cells

TWIST2 Was Deregulated In Human Acute Myeloid Leukemia and Might Play a Tumor Suppressor Role

The Potential Role of Galectin-1 in Hypoxia Induced AML Cell Differentiation through C/EBPαa Transcription Regulation.

Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential

Identification of AHI-1 Involvement in Mediating Cellular Resistance to Imatinib Mesylate in Chronic Myeloid Leukemia Cells

A Novel Strategy for Expanding Primitive Leukemic Cells from Chronic Phase CML Patients by Forced Overexpression of a NUP98-HOXA10 Homeodomain Fusion Gene.

Differentially Expressed and Novel Transcripts in Highly Purified Chronic Phase CML Stem Cells

Interaction of a Novel Signaling Protein (AHI-1) with BCR-ABL Modulates BCR-ABL Transforming Activity and Imatinib Response of Chronic Myeloid Leukemia Progenitor Cells.

Comparative Transcriptome Analysis of Different Subsets of CD34 + Normal and Chronic Myeloid Leukemia Cells Identifies Novel Perturbations in the CML Stem Cell Population.

Differences in the Transcriptomes of Highly Purified Fetal Liver and Adult Bone Marrow Hematopoietic Stem Cells Revealed by Long Serial Analysis of Gene Expression (LongSAGE)

Chronic Myeloid Leukemia Stem Cells Possess Unique Properties That Predict Intrinsic and Acquired Resistance to Imatinib Mesylate.

Leukemic Stem Cells of Chronic Phase CML Patients Consistently Display Very High BCR-ABL Transcript Levels and Reduced Responsiveness to Imatinib Mesylate in Addition to Generating a Rare Subset That Produce Imatinib Mesylate-Resistant Differentiated Progeny.

Deregulated expression in Ph + human leukemias of AHI-1 , a gene activated by insertional mutagenesis in mouse models of leukemia

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American Society of Hematology

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American Society of Hematology

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