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Leon Zhou
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Journal Articles

The WD40-Repeats of Ahi-1 Oncogene Critical for Protein Interaction Between Ahi-1 and BCR-ABL Modulates Imatinib-Induced Apoptosis In BCR-ABL-Transduced Cells

Min Chen, PhD, Leon Zhou, PhD, Matthew Chan, PhD, Damian Lai, Ali G. Turhan, MD, PhD, Ralph B. Arlinghaus, PhD, Xiaoyan Jiang, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 4181.
https://doi.org/10.1182/blood.V116.21.4181.4181
Published: 2010
Journal Articles

Combined Targeting of BCR-ABL and JAK2 with ABL and JAK2 Inhibitors Is Effective Against CML Patients' Leukemic Stem/Progenitor Cells.

Donna DeGeer, MSc, Paolo Gallipoli, MD, Min Chen, PhD, Ivan Sloma, PhD, Heather Jorgensen, PhD, Donna Forrest, MD, Karen Lambie, Helen Nakamoto, Kyi Min Saw, Matthew Chan, Kathleen Newmarch, Leon Zhou, Ali G. Turhan, MD, PhD, Ralph B. Arlinghaus, PhD, Allen C. Eaves, MD, FRCPC, PhD, Connie J. Eaves, PhD, Tessa L. Holyoake, PhD, FRCP, FRCPath, Xiaoyan Jiang, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3404.
https://doi.org/10.1182/blood.V116.21.3404.3404
Published: 2010
Journal Articles

A Novel AHI-1-BCR-ABL-JAK2 Interaction Complex Mediates Cellular Resistance to Tyrosine Kinase Inhibitors in CML .

Donna DeGeer, Kathleen Newmarch, Leon Zhou, Min Chen, MD, PhD, Kyi Min Saw, Ali G Turhan, M.D., PhD, Xiaoyan Jiang, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 38.
https://doi.org/10.1182/blood.V114.22.38.38
Published: 2009
Journal Articles

Identification of AHI-1 Involvement in Mediating Cellular Resistance to Imatinib Mesylate in Chronic Myeloid Leukemia Cells

Donna DeGeer, Leon Zhou, Min Chen, MD, PhD, Yun Zhao, Ali G Turhan, M.D., PhD, Xiaoyan Jiang, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3201.
https://doi.org/10.1182/blood.V112.11.3201.3201
Published: 2008
Journal Articles

Direct Interaction of Ahi-1 with BCR-ABL Modulates BCR-ABL Transforming Activity and Imatinib Response in a BCR-ABL Inducible Cell Line Model

Min Chen, M.D., PhD, Leon Zhou, Donna DeGeer, Ranko Vukovic, Ali G Turhan, M.D., PhD, Xiaoyan Jiang, M.D., PhD
Journal: Blood
Blood (2008) 112 (11): 4217.
https://doi.org/10.1182/blood.V112.11.4217.4217
Published: 2008
Journal Articles

Interaction of a Novel Signaling Protein (AHI-1) with BCR-ABL Modulates BCR-ABL Transforming Activity and Imatinib Response of Chronic Myeloid Leukemia Progenitor Cells.

Yun Zhao, PhD, Leon Zhou, MS, Ashley Ringrose, BS, Ann E.-J. Lin, BS, Erin Kennah, MS, Guoqing Sheng, PhD, Xiao-Jiang Li, PhD, Ali Turhan, PhD, Xiaoyan Jiang, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 467.
https://doi.org/10.1182/blood.V110.11.467.467
Published: 2007
Journal Articles

Deregulated Expression of a Novel Oncogene, Ahi-1, in Murine Hematopoietic Cells Confers a Proliferative Advantage In Vitro and Leukemogenic Activity In Vivo and Enhances the Effects of BCR-ABL.

Leon Zhou, Ashley Ringrose, Ann E.-J. Lin, Xiaoyan Jiang, MD,PhD
Journal: Blood
Blood (2006) 108 (11): 388.
https://doi.org/10.1182/blood.V108.11.388.388
Published: 2006
Journal Articles

Forced Overexpression of Ahi-1 Confers a Proliferative Advantage on Primitive Murine Hematopoietic Cells and Enhances the Effects of BCR-ABL.

Leon Zhou, Ashley Ringrose, Xiaoyan Jiang, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 2573.
https://doi.org/10.1182/blood.V104.11.2573.2573
Published: 2004