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Karina Barbosa
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Journal Articles

Transcriptional control of leukemogenesis by the chromatin reader SGF29

Karina Barbosa, Anagha Deshpande, Marlenne Perales, Ping Xiang, Rabi Murad, Akula Bala Pramod, Anna Minkina, Neil Robertson, Fiorella Schischlik, Xue Lei, Younguk Sun, Adam Brown, Diana Amend, Irmela Jeremias, John G. Doench, R. Keith Humphries, Eytan Ruppin, Jay Shendure, Prashant Mali, Peter D. Adams, Aniruddha J. Deshpande
Journal: Blood
Blood (2024) 143 (8): 697–712.
https://doi.org/10.1182/blood.2023021234
Published: 2024
Includes: Supplemental data
Journal Articles

A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML

Bo-Rui Chen, Anagha Deshpande, Karina Barbosa, Maria Kleppe, Xue Lei, Narayana Yeddula, Pablo Sánchez Vela, Alexandre Rosa Campos, Robert J. Wechsler-Reya, Anindya Bagchi, Soheil Meshinchi, Connie Eaves, Irmela Jeremias, Torsten Haferlach, David A. Frank, Ze’ev Ronai, Sumit Chanda, Scott A. Armstrong, Peter D. Adams, Ross L. Levine, Aniruddha J. Deshpande
Journal: Blood
Blood (2021) 137 (24): 3403–3415.
https://doi.org/10.1182/blood.2020009023
Published: 2021
Includes: Supplemental data
Journal Articles

High-Density Domain-Focused CRISPR Screens Reveal Epigenetic Regulators of Hox/Meis Gene Expression in Acute Myeloid Leukemia

Karina Barbosa, BSc, Anagha Deshpande, PhD, Ping Xiang, PhD, Bo-Rui Chen, PhD, Adam Brown, MSc, Neil Robertson, Younguk Sun, PhD, John Doench, PhD, Peter D Adams, PhD, R. Keith Humphries, MD PhD, Prashant Mali, PhD, Aniruddha J. Deshpande, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
https://doi.org/10.1182/blood-2020-141412
Published: 2020
Journal Articles

A Synthetic Lethal Approach to Eradicate AML Via Synergistic Activation of Pro-Apoptotic p53 By MDM2 and BET Inhibitors

Sha Li, Anne-Louise Latif, Ashley Newcombe, Kathryn Gilrory, Neil Robertson, Xue Lei, Darren Finlay, PhD, Karina Barbosa, BSc, Helen Stewart, John Cole, Maria Terradas Terradas, Loveena Rishi Delori, Lynn McGarry, Claire McKeeve, Claire Reid, William Clark, Joana Campos, Kristina Kirschner, Andrew Davis, Jonathan Lopez, Jun-Ichi Sakamaki, Jennifer Morton, Kevin Ryan, Stephen Tait, Sheela Abraham, Tessa L. Holyoake, MD PhD FRCP, FRCPath, Brian Higgins, Xu Huang, BSc, PhD, Karen Blyth, Mhairi Copland, PhD MBBChir, FRCP, FRCPath, Timothy Chevassut, Aniruddha J. Deshpande, PhD, Karen Keeshan, Peter Adams, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14.
https://doi.org/10.1182/blood-2020-143079
Published: 2020