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Journal Articles

Transcriptional control of leukemogenesis by the chromatin reader SGF29

Karina Barbosa, Anagha Deshpande, Marlenne Perales, Ping Xiang, Rabi Murad, Akula Bala Pramod, Anna Minkina, Neil Robertson, Fiorella Schischlik, Xue Lei, Younguk Sun, Adam Brown, Diana Amend, Irmela Jeremias, John G. Doench, R. Keith Humphries, Eytan Ruppin, Jay Shendure, Prashant Mali, Peter D. Adams, Aniruddha J. Deshpande
Journal: Blood
Blood (2024) 143 (8): 697–712.
https://doi.org/10.1182/blood.2023021234
Published: 2024
Includes: Supplemental data
Journal Articles

WT1 and DNMT3A play essential roles in the growth of certain patient AML cells in mice

Maryam Ghalandary, Yuqiao Gao, Diana Amend, Ginte Kutkaite, Binje Vick, Karsten Spiekermann, Maja Rothenberg-Thurley, Klaus H. Metzeler, Anetta Marcinek, Marion Subklewe, Michael P. Menden, Vindi Jurinovic, Ehsan Bahrami, Irmela Jeremias
Journal: Blood
Blood (2023) 141 (8): 955–960.
https://doi.org/10.1182/blood.2022016411
Published: 2023
Includes: Supplemental data
Journal Articles

WT1 and DNMT3A Play an Essential Function and Represent Therapeutic Vulnerabilities in Certain AML Samples, As Shown By CRISPR/Cas9 Mediated Knockout in PDX Models In Vivo

Maryam Ghalandary, Yuqiao Gao, Martin Becker, Diana Amend, Klaus H. Metzeler, Maja Rothenberg-Thurley, Irmela Jeremias
Journal: Blood
Blood (2021) 138 (Supplement 1): 377.
https://doi.org/10.1182/blood-2021-150305
Published: 2021
Journal Articles

Efficient Correction of HAX1 Mutations in Primary HSPCs of Severe Congenital Neutropenia Patients Using CRISPR/CAS9 GENE-Editing

Malte U Ritter, Benjamin Secker, Masoud Nasri, MSc, Maksim Klimiankou, Benjamin Dannenmann, MSc, Diana Amend, Jeremy Haaf, Msc, Perihan Mir, Regine Bernhard, Ingeborg Steiert, Cornelia Zeidler, Karl Welte, Julia Skokowa, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 22.
https://doi.org/10.1182/blood-2020-140260
Published: 2020
Journal Articles

Disease Modeling of Severe Congenital Neutropenia Using CRISPR/Cas9 Gene Correction or Knockout of ELANE in Patients Derived Induced Pluripotent Stem Cells

Masoud Nasri, MSc, Benjamin Dannenmann, Perihan Mir, Malte U Ritter, Diana Amend, Yun Xu, Maksim Klimiankou, Cornelia Zeidler, Karl Welte, Julia Skokowa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 434.
https://doi.org/10.1182/blood-2019-129991
Published: 2019
Journal Articles

A Method to Fluorescently Label the CRISPR/Cas9-gRNA RNP Complexes Enables Enrichment of Clinical-Grade Gene-Edited Primary Hematopoietic Stem Cells and iPSCs

Masoud Nasri, Perihan Mir, Benjamin Dannenmann, Diana Amend, Yun Xu, Anna Solovyeva, Sylwia Stefanczyk, Maksim Klimiankou, Cornelia Zeidler, Lothar Kanz, Karl Welte, Julia Skokowa, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1108.
https://doi.org/10.1182/blood-2018-99-114844
Published: 2018
Journal Articles

Effects of CSF3R mutations on Myeloid Differentiation and Proliferation of Hematopoietic Cells of Congenital Neutropenia Patients

Maksim Klimiankou, Benjamin Dannenmann, Anna Solovyeva, Regine Bernhard, Diana Amend, Cornelia Zeidler, Sabine Mellor-Heineke, MD, Lothar Kanz, Julia Skokowa, Karl Welte, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2278.
https://doi.org/10.1182/blood.V130.Suppl_1.2278.2278
Published: 2017