Page 1 | Search Results | Blood | American Society of Hematology

1-18 of 18

Sort by

Sort Order Select

Journal Articles

Flavopiridol Restores Granulopoiesis in an Experimental Model of Severe Congenital Neutropenia

Benjamin Dannenmann, Masoud Nasri, Larissa Doll, Betül Findik, Franka Bernhard, Sergey Kandabarau, Maksim Klimiankou, Claudia Lengerke, Cornelia Zeidler, Karl Welte, Julia Skokowa

Blood (2024) 144 (Supplement 1): 419.

https://doi.org/10.1182/blood-2024-209864

Published: 2024

Journal Articles

A Pipeline for Comparison and Selection of Clinically Applicable Gene Therapy Approaches for ELANE -Associated Severe Congenital Neutropenia

Malte Ulrich Ritter, Masoud Nasri, Benjamin Dannenmann, Perihan Mir, Benjamin Secker, Cornelia Zeidler, Maksim Klimiankou, Karl Welte, Julia Skokowa

Blood (2023) 142 (Supplement 1): 934.

https://doi.org/10.1182/blood-2023-188707

Published: 2023

Journal Articles

A Universal CRISPR/Cas9n-Mediated Genome Editing Approach for ELANE -Related Severe Congenital Neutropenia

Masoud Nasri, Malte Ulrich Ritter, Perihan Mir, Benjamin Dannenmann, Masako Monika Kaufmann, Yun Xu, Natalia Borbaran-Bravo, Maksim Klimiankou, Claudia Lengerke, Cornelia Zeidler, Toni Cathomen, Karl Welte, Julia Skokowa

Blood (2023) 142 (Supplement 1): 932.

https://doi.org/10.1182/blood-2023-181678

Published: 2023

Journal Articles

Efficient Correction of HAX1 Mutations in Primary HSPCs of Severe Congenital Neutropenia Patients Using CRISPR/CAS9 GENE-Editing

Malte U Ritter, Benjamin Secker, Masoud Nasri, MSc, Maksim Klimiankou, Benjamin Dannenmann, MSc, Diana Amend, Jeremy Haaf, Msc, Perihan Mir, Regine Bernhard, Ingeborg Steiert, Cornelia Zeidler, Karl Welte, Julia Skokowa, MDPhD

Blood (2020) 136 (Supplement 1): 22.

https://doi.org/10.1182/blood-2020-140260

Published: 2020

Journal Articles

Transcriptome Analysis of Severe Congenital Neutropenia Associated Leukemia with Different Types of RUNX1 Mutations in an iPSC-Based Model

Benjamin Dannenmann, MSc, Benedikt Oswald, Malte U Ritter, Masoud Nasri, MSc, Regine Bernhard, Cornelia Zeidler, Karl Welte, Julia Skokowa, MDPhD, Maksim Klimiankou

Blood (2020) 136 (Supplement 1): 23–24.

https://doi.org/10.1182/blood-2020-142524

Published: 2020

Journal Articles

Disease Modeling of Severe Congenital Neutropenia Using CRISPR/Cas9 Gene Correction or Knockout of ELANE in Patients Derived Induced Pluripotent Stem Cells

Masoud Nasri, MSc, Benjamin Dannenmann, Perihan Mir, Malte U Ritter, Diana Amend, Yun Xu, Maksim Klimiankou, Cornelia Zeidler, Karl Welte, Julia Skokowa, MD PhD

Blood (2019) 134 (Supplement_1): 434.

https://doi.org/10.1182/blood-2019-129991

Published: 2019

Journal Articles

Efficient Correction of ELANE mutations in Primary HSPCs of Severe Congenital Neutropenia Patients Using CRISPR/Cas9 and rAVV6 HDR Repair Templates

Malte U Ritter, Benjamin Secker, Maksim Klimiankou, Masoud Nasri, MSc, Narges Aghaallaei, Benjamin Dannenmann, Regine Bernhard, Ingeborg Steiert, Karin Haehnel, Baubak Bajoghli, Cornelia Zeidler, Karl Welte, Julia Skokowa, MD PhD

Blood (2019) 134 (Supplement_1): 1036.

https://doi.org/10.1182/blood-2019-131708

Published: 2019

Journal Articles

LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis

Blood (2019) 134 (14): 1159–1175.

https://doi.org/10.1182/blood.2019000095

Published: 2019

Includes: Supplemental data

Journal Articles

GADD45b Plays an Essential Role in the G-CSF Triggered Granulocytic Differentiation of Human Hematopoietic Cells

Perihan Mir, Masoud Nasri, Benjamin Dannenmann, Maksim Klimiankou, Betuel Findik, Regine Bernhard, Michael A. Rieger, Cornelia Zeidler, Lothar Kanz, Karl Welte, Julia Skokowa, MDPhD

Blood (2018) 132 (Supplement 1): 17.

https://doi.org/10.1182/blood-2018-99-114875

Published: 2018

Journal Articles

CRISPR/Cas9 Knock-in HL60 Cells Closely Simulate Cellular and Functional Abnormalities of ELANE associated Neutropenia; Phenotype Rescue with MK-0339 Neutrophil Elastase Inhibitor

Vahagn Makaryan, MD, Breanna Fletcher, BSc, Merideth L. Kelley, MSc, Masoud Nasri, Julia Skokowa, MD PhD, Karl Welte, David C Dale, MD

Blood (2018) 132 (Supplement 1): 3683.

https://doi.org/10.1182/blood-2018-99-113054

Published: 2018

Journal Articles

Mechanism of BAALC-Mediated Leukemogenesis Downstream of RUNX1 -Mutations in Severe Congenital Neutropenia

Benjamin Dannenmann, Maksim Klimiankou, Benedikt Oswald, Malte U Ritter, Masoud Nasri, Anna Solovyeva, Lothar Kanz, Cornelia Zeidler, Karl Welte, Julia Skokowa, MDPhD

Blood (2018) 132 (Supplement 1): 13.

https://doi.org/10.1182/blood-2018-99-118558

Published: 2018

Journal Articles

A Method to Fluorescently Label the CRISPR/Cas9-gRNA RNP Complexes Enables Enrichment of Clinical-Grade Gene-Edited Primary Hematopoietic Stem Cells and iPSCs

Masoud Nasri, Perihan Mir, Benjamin Dannenmann, Diana Amend, Yun Xu, Anna Solovyeva, Sylwia Stefanczyk, Maksim Klimiankou, Cornelia Zeidler, Lothar Kanz, Karl Welte, Julia Skokowa, MDPhD

Blood (2018) 132 (Supplement 1): 1108.

https://doi.org/10.1182/blood-2018-99-114844

Published: 2018

Journal Articles

Establishment of the Safe and Efficient CRISPR/Cas9-RNP Based Gene-Correction Platform of ELANE Mutations in iPSCs of Severe Congenital Neutropenia (CN) Patients with No Response to G-CSF and High Risk to Develop Leukemia

Masoud Nasri, MSc, Benjamin Dannenmann, Perihan Mir, Tessa Skroblyn, Anna Solovjeva, Maksim Klimiankou, Cornelia Zeidler, Lothar Kanz, Karl Welte, Julia Skokowa

Blood (2017) 130 (Supplement 1): 542.

https://doi.org/10.1182/blood.V130.Suppl_1.542.542

Published: 2017

Journal Articles

BAALC Is a Key Mediator of Leukemia Development in Congenital Neutropenia

Benjamin Dannenmann, Maksim Klimiankou, Anna Solovyeva, Azadeh Zahabi, MSc, Perihan Mir, Masoud Nasri, MSc, Regine Bernhard, Christian Lindner, Tatsuya Morishima, MD PhD, Doris Steinemann, PhD, Cornelia Zeidler, Lothar Kanz, Karl Welte, MD PhD, Julia Skokowa

Blood (2017) 130 (Supplement 1): 541.

https://doi.org/10.1182/blood.V130.Suppl_1.541.541

Published: 2017

Journal Articles

Cell-Stage Dependent Outcomes of the NAMPT/SIRT2-Mediated Activation of LMO2 By Deacetylation in Normal Hematopoiesis and in T-ALL

Tatsuya Morishima, MD PhD, Christian Lindner, Benedikt Oswald, Marcus Hartmann, Masoud Nasri, MSc, Lothar Kanz, Patrick Müller, Karl Welte, Julia Skokowa

Blood (2017) 130 (Supplement 1): 1154.

https://doi.org/10.1182/blood.V130.Suppl_1.1154.1154

Published: 2017

Journal Articles

Abrogated GADD45b-Mediated Integrity Control of Hematopoietic Stem Cells upon ER Stress and DNA Damage Triggers Lymphopoiesis over Granulopoiesis in Congenital Neutropenia

Perihan Mir, Masoud Nasri, MSc, Benjamin Dannenmann, Karin Haehnel, Maksim Klimiankou, Cornelia Zeidler, Lothar Kanz, Karl Welte, Julia Skokowa

Blood (2017) 130 (Supplement 1): 450.

https://doi.org/10.1182/blood.V130.Suppl_1.450.450

Published: 2017

Journal Articles

Activation of C/EBPa Myeloid-Specific Transcription Factor By NAMPT/SIRT1-Triggered Deacetylation

Bardia Samareh, PhD, Masoud Nasri, M.Sc, Inna Zimmer, Olga Klimenkova, PhD, Leonie Keller, Lothar Kanz, Prof. Dr. MD, Karl Welte, Prof. Dr. MD, Julia Skokowa, Prof. Dr.

Blood (2015) 126 (23): 2199.

https://doi.org/10.1182/blood.V126.23.2199.2199

Published: 2015

Journal Articles

SIRT2 Plays Essential Role in Early Hematopoiesis through Deacetylation of LMO2 Protein

Tatsuya Morishima, MD PhD, Regine Bernhard, Azadeh Zahabi, Benjamin Dannenmann, Masoud Nasri, M.Sc, Bardia Samareh, PhD, Lothar Kanz, Prof. Dr. MD, Karl Welte, MD, Julia Skokowa, Prof. Dr.

Blood (2015) 126 (23): 3574.

https://doi.org/10.1182/blood.V126.23.3574.3574

Published: 2015

NARROW

Flavopiridol Restores Granulopoiesis in an Experimental Model of Severe Congenital Neutropenia

A Pipeline for Comparison and Selection of Clinically Applicable Gene Therapy Approaches for ELANE -Associated Severe Congenital Neutropenia

A Universal CRISPR/Cas9n-Mediated Genome Editing Approach for ELANE -Related Severe Congenital Neutropenia

Efficient Correction of HAX1 Mutations in Primary HSPCs of Severe Congenital Neutropenia Patients Using CRISPR/CAS9 GENE-Editing

Transcriptome Analysis of Severe Congenital Neutropenia Associated Leukemia with Different Types of RUNX1 Mutations in an iPSC-Based Model

Disease Modeling of Severe Congenital Neutropenia Using CRISPR/Cas9 Gene Correction or Knockout of ELANE in Patients Derived Induced Pluripotent Stem Cells

Efficient Correction of ELANE mutations in Primary HSPCs of Severe Congenital Neutropenia Patients Using CRISPR/Cas9 and rAVV6 HDR Repair Templates

LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis

GADD45b Plays an Essential Role in the G-CSF Triggered Granulocytic Differentiation of Human Hematopoietic Cells

CRISPR/Cas9 Knock-in HL60 Cells Closely Simulate Cellular and Functional Abnormalities of ELANE associated Neutropenia; Phenotype Rescue with MK-0339 Neutrophil Elastase Inhibitor

Mechanism of BAALC-Mediated Leukemogenesis Downstream of RUNX1 -Mutations in Severe Congenital Neutropenia

A Method to Fluorescently Label the CRISPR/Cas9-gRNA RNP Complexes Enables Enrichment of Clinical-Grade Gene-Edited Primary Hematopoietic Stem Cells and iPSCs

Establishment of the Safe and Efficient CRISPR/Cas9-RNP Based Gene-Correction Platform of ELANE Mutations in iPSCs of Severe Congenital Neutropenia (CN) Patients with No Response to G-CSF and High Risk to Develop Leukemia

BAALC Is a Key Mediator of Leukemia Development in Congenital Neutropenia

Cell-Stage Dependent Outcomes of the NAMPT/SIRT2-Mediated Activation of LMO2 By Deacetylation in Normal Hematopoiesis and in T-ALL

Abrogated GADD45b-Mediated Integrity Control of Hematopoietic Stem Cells upon ER Stress and DNA Damage Triggers Lymphopoiesis over Granulopoiesis in Congenital Neutropenia

Activation of C/EBPa Myeloid-Specific Transcription Factor By NAMPT/SIRT1-Triggered Deacetylation

SIRT2 Plays Essential Role in Early Hematopoiesis through Deacetylation of LMO2 Protein

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only