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Journal Articles

Terminal Erythroid Differentiation Is Regulated By Mitochondrial Translation Via Maintenance of Iron Homeostasis

Tatsuya Morishima, Md Fakruddin, Takeshi Masuda, Yuxin Wang, Vivien A.C. Schoonenberg, Falk Butter, Yuichiro Arima, Kazuhito Tomizawa, Fan-Yan Wei, Toshio Suda, Hitoshi Takizawa
Journal: Blood
Blood (2022) 140 (Supplement 1): 2203–2204.
https://doi.org/10.1182/blood-2022-162991
Published: 2022
Journal Articles

Oncometabolite-Independent Anti-Apoptotic Feature Via Phospholipid Metabolic Adaptation in IDH2 Mutant AML Cells

Tatsuya Morishima, Koichi Takahashi, Desmond Wai Loon Chin, Kenji Tokunaga, Yuichiro Arima, Masao Matsuoka, Toshio Suda, Hitoshi Takizawa
Journal: Blood
Blood (2022) 140 (Supplement 1): 3012–3013.
https://doi.org/10.1182/blood-2022-162976
Published: 2022
Journal Articles

Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans

Nicole Mende, Hugo P. Bastos, Antonella Santoro, Krishnaa T. Mahbubani, Valerio Ciaurro, Emily F. Calderbank, Mariana Quiroga Londoño, Kendig Sham, Giovanna Mantica, Tatsuya Morishima, Emily Mitchell, Maria Rosa Lidonnici, Fabienne Meier-Abt, Daniel Hayler, Laura Jardine, Abbie Curd, Muzlifah Haniffa, Giuliana Ferrari, Hitoshi Takizawa, Nicola K. Wilson, Berthold Göttgens, Kourosh Saeb-Parsy, Mattia Frontini, Elisa Laurenti
Journal: Blood
Blood (2022) 139 (23): 3387–3401.
https://doi.org/10.1182/blood.2021013450
Published: 2022
Includes: Supplemental data
Journal Articles

LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis

Tatsuya Morishima, Ann-Christin Krahl, Masoud Nasri, Yun Xu, Narges Aghaallaei, Betül Findik, Maksim Klimiankou, Malte Ritter, Marcus D. Hartmann, Christian Johannes Gloeckner, Sylwia Stefanczyk, Christian Lindner, Benedikt Oswald, Regine Bernhard, Karin Hähnel, Ursula Hermanutz-Klein, Martin Ebinger, Rupert Handgretinger, Nicolas Casadei, Karl Welte, Maya Andre, Patrick Müller, Baubak Bajoghli, Julia Skokowa
Journal: Blood
Blood (2019) 134 (14): 1159–1175.
https://doi.org/10.1182/blood.2019000095
Published: 2019
Includes: Supplemental data
Journal Articles

BAALC Is a Key Mediator of Leukemia Development in Congenital Neutropenia

Benjamin Dannenmann, Maksim Klimiankou, Anna Solovyeva, Azadeh Zahabi, MSc, Perihan Mir, Masoud Nasri, MSc, Regine Bernhard, Christian Lindner, Tatsuya Morishima, MD PhD, Doris Steinemann, PhD, Cornelia Zeidler, Lothar Kanz, Karl Welte, MD PhD, Julia Skokowa
Journal: Blood
Blood (2017) 130 (Supplement 1): 541.
https://doi.org/10.1182/blood.V130.Suppl_1.541.541
Published: 2017
Journal Articles

Cell-Stage Dependent Outcomes of the NAMPT/SIRT2-Mediated Activation of LMO2 By Deacetylation in Normal Hematopoiesis and in T-ALL

Tatsuya Morishima, MD PhD, Christian Lindner, Benedikt Oswald, Marcus Hartmann, Masoud Nasri, MSc, Lothar Kanz, Patrick Müller, Karl Welte, Julia Skokowa
Journal: Blood
Blood (2017) 130 (Supplement 1): 1154.
https://doi.org/10.1182/blood.V130.Suppl_1.1154.1154
Published: 2017
Journal Articles

Analysis of Leukemogenic Effects of RUNX1 and CSF3R Mutations Using Congenital Neutropenia (CN)/AML Patient-Derived Induced Pluripotent Stem Cells (iPSCs)

Benjamin Dannenmann, M.Sc., Maksim Klimiankou, PhD, Christian Lindner, B.Sc., Azadeh Zahabi, M.Sc., Regine Bernhard, Tatsuya Morishima, MD PhD, Cornelia Zeidler, MD, Lothar Kanz, MD, Karl Welte, MD, Julia Skokowa, MD PhD
Journal: Blood
Blood (2016) 128 (22): 404.
https://doi.org/10.1182/blood.V128.22.404.404
Published: 2016
Journal Articles

Thrombopoietin (TPO) Induces Hematopoietic Differentiation of Mouse ES Cells Via HIF-1 Alpha-Dependent Activation of a BMP4 Autoregulatory Loop

Azadeh Zahabi, Tatsuya Morishima, MD PhD, Andri Pramono, Dan Lan, Lothar Kanz, MD, Karl Welte, MD, Julia Skokowa, Prof. Dr.
Journal: Blood
Blood (2015) 126 (23): 1186.
https://doi.org/10.1182/blood.V126.23.1186.1186
Published: 2015
Journal Articles

SIRT2 Plays Essential Role in Early Hematopoiesis through Deacetylation of LMO2 Protein

Tatsuya Morishima, MD PhD, Regine Bernhard, Azadeh Zahabi, Benjamin Dannenmann, Masoud Nasri, M.Sc, Bardia Samareh, PhD, Lothar Kanz, Prof. Dr. MD, Karl Welte, MD, Julia Skokowa, Prof. Dr.
Journal: Blood
Blood (2015) 126 (23): 3574.
https://doi.org/10.1182/blood.V126.23.3574.3574
Published: 2015
Journal Articles

Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome

Satoshi Saida, Ken-ichiro Watanabe, Aiko Sato-Otsubo, Kiminori Terui, Kenichi Yoshida, Yusuke Okuno, Tsutomu Toki, RuNan Wang, Yuichi Shiraishi, Satoru Miyano, Itaru Kato, Tatsuya Morishima, Hisanori Fujino, Katsutsugu Umeda, Hidefumi Hiramatsu, Souichi Adachi, Etsuro Ito, Seishi Ogawa, Mamoru Ito, Tatsutoshi Nakahata, Toshio Heike
Journal: Blood
Blood (2013) 121 (21): 4377–4387.
https://doi.org/10.1182/blood-2012-12-474387
Published: 2013
Includes: Supplemental data
Journal Articles

Reduced Production of Mature Neutrophils From Induced Pluripotent Stem Cells Derived From a Severe Congenital Neutropenia Patient with HAX1 Gene Deficiency

Tatsuya Morishima, MD, Ken-ichiro Watanabe, MD, PhD, Akira Niwa, MD, PhD, Takayuki Tanaka, MD, Katsutsugu Umeda, MD, PhD, Hidefumi Hiramatsu, MD, PhD, Kousaku Matsubara, MD, PhD, Souichi Adachi, MD, PhD, Tatsutoshi Nakahata, MD, PhD, Toshio Heike, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2402.
https://doi.org/10.1182/blood.V118.21.2402.2402
Published: 2011
Journal Articles

Analyzing the Stepwise Developmental Pathway From ES/IPS Cells to Functional Mature Erythrocytes.

Akira Niwa, M.D., Tomoki Fukatsu, Katsutsugu Umeda, M.D., PhD., Itaru Kato, M.D., Hiromi Sakai, PhD., Tatsuya Morishima, M.D., Keisuke Okita, PhD., Shinya Yamanaka, M.D., PhD., Toshio Heike, M.D., PhD., Tatsutoshi Nakahata, M.D., Ph.D.
Journal: Blood
Blood (2009) 114 (22): 2534.
https://doi.org/10.1182/blood.V114.22.2534.2534
Published: 2009