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Masao Matsuoka
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Journal Articles

Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis

Mingrui Guo, Tim Hon Man Chan, Qiling Zhou, Omer An, Ying Li, Yangyang Song, Zi Hui Tan, Vanessa Hui En Ng, Philomina Sona Peramangalam, Zhi Qing Tan, Xinang Cao, Eisaku Iwanaga, Masao Matsuoka, Melissa G. M. Ooi, Wei Ying Jen, Liang Piu Koh, Esther Chan, Lip Kun Tan, Yufen Goh, Wilson Wang, Bryan T. H. Koh, Chan Ming Chun, Melissa J. Fullwood, Wee Joo Chng, Motomi Osato, John Anto Pulikkan, Henry Yang, Leilei Chen, Daniel G. Tenen
Journal: Blood
Blood (2023) 141 (25): 3078–3090.
https://doi.org/10.1182/blood.2022015830
Published: 2023
Includes: Supplemental data
Journal Articles

Oncometabolite-Independent Anti-Apoptotic Feature Via Phospholipid Metabolic Adaptation in IDH2 Mutant AML Cells

Tatsuya Morishima, Koichi Takahashi, Desmond Wai Loon Chin, Kenji Tokunaga, Yuichiro Arima, Masao Matsuoka, Toshio Suda, Hitoshi Takizawa
Journal: Blood
Blood (2022) 140 (Supplement 1): 3012–3013.
https://doi.org/10.1182/blood-2022-162976
Published: 2022
Journal Articles

Targeting vulnerabilities of adult T-cell leukemia

Masao Matsuoka
Journal: Blood
Blood (2022) 139 (10): 1435.
https://doi.org/10.1182/blood.2021014879
Published: 2022
Journal Articles

Whole-genome landscape of adult T-cell leukemia/lymphoma

Yasunori Kogure, Takuro Kameda, Junji Koya, Makoto Yoshimitsu, Kisato Nosaka, Jun-ichirou Yasunaga, Yoshitaka Imaizumi, Mizuki Watanabe, Yuki Saito, Yuta Ito, Marni B. McClure, Mariko Tabata, Sumito Shingaki, Kota Yoshifuji, Kenichi Chiba, Ai Okada, Nobuyuki Kakiuchi, Yasuhito Nannya, Ayako Kamiunten, Yuki Tahira, Keiichi Akizuki, Masaaki Sekine, Kotaro Shide, Tomonori Hidaka, Yoko Kubuki, Akira Kitanaka, Michihiro Hidaka, Nobuaki Nakano, Atae Utsunomiya, R. Alejandro Sica, Ana Acuna-Villaorduna, Murali Janakiram, Urvi Shah, Juan Carlos Ramos, Tatsuhiro Shibata, Kengo Takeuchi, Akifumi Takaori-Kondo, Yasushi Miyazaki, Masao Matsuoka, Kenji Ishitsuka, Yuichi Shiraishi, Satoru Miyano, Seishi Ogawa, B. Hilda Ye, Kazuya Shimoda, Keisuke Kataoka
Journal: Blood
Blood (2022) 139 (7): 967–982.
https://doi.org/10.1182/blood.2021013568
Published: 2022
Includes: Supplemental data
Journal Articles

The Role of CD38 in Multiple Myeloma Cell Biology

Yawara Kawano, Saki Kushima, Hiroyuki Hata, Masao Matsuoka
Journal: Blood
Blood (2021) 138 (Supplement 1): 1580.
https://doi.org/10.1182/blood-2021-150884
Published: 2021
Journal Articles

Oncofetal Protein SALL4 Is Highly Expressed in Myelodysplastic Syndrome Alongside with NAT10 and P53

Hiro Tatetsu, MD, Miho Watanabe, MD, Emily F Mason, MD PhD, Scott B Lovitch, MDPhD, Kenji Tokunaga, MD, Eisaku Iwanaga, MD, Masao Matsuoka, MDPhD, Daniel G. Tenen, MD, Li Chai, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-134533
Published: 2020
Journal Articles

Whole-Genome Analysis of Adult T-Cell Leukemia/Lymphoma

Yasunori Kogure, MD PhD, Takuro Kameda, MD PhD, Junji Koya, PhD MD, Ayako Kamiunten, MD, Kotaro Shide, MD PhD, Tomonori Hidaka, MD, Yoko Kubuki, MD PhD, Makoto Yoshimitsu, MD PhD, Kisato Nosaka, MD PhD, Yoshitaka Imaizumi, MD PhD, Mizuki Watanabe, MD, Yuki Saito, MD, Marni B McClure, MD PhD, Mariko Tabata, MD, Sumito Shingaki, PhD MD, Kota Yoshifuji, MD, Yuichi Shiraishi, PhD, Michihiro Hidaka, MD PhD, Atae Utsunomiya, MD, Urvi A. Shah, MD, Ana Acuna-Villaorduna, MD, Aditi Shastri, MD, R. Alejandro Sica, MD, Murali Janakiram, MD, Juan Carlos Ramos, MD BS, Tatsuhiro Shibata, MD PhD, Akifumi Takaori-Kondo, MD PhD, Yasushi Miyazaki, MD PhD, Masao Matsuoka, MDPhD, Kenji Ishitsuka, MD PhD, Seishi Ogawa, MD PhD, B. Hilda Ye, PhD, Kazuya Shimoda, MD PhD, Keisuke Kataoka, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–30.
https://doi.org/10.1182/blood-2020-134360
Published: 2020
Journal Articles

Hematopoietic stem cells acquire survival advantage by loss of RUNX1 methylation identified in familial leukemia

Clinical Trials & Observations
Takayoshi Matsumura, Ayako Nakamura-Ishizu, Siva Sai Naga Anurag Muddineni, Darren Qiancheng Tan, Chelsia Qiuxia Wang, Kenji Tokunaga, Roberto Tirado-Magallanes, Stephanie Sian, Touati Benoukraf, Tsukasa Okuda, Norio Asou, Masao Matsuoka, Motomi Osato, Toshio Suda
Journal: Blood
Blood (2020) 136 (17): 1919–1932.
https://doi.org/10.1182/blood.2019004292
Published: 2020
Includes: Supplemental data
Journal Articles

Targeting Nicotinamide Adenine Dinucleotide (NAD) Glycohydrase Activity of CD38 Exerts Anti-Myeloma Effect Accompanying Intracellular NAD Elevation

Saki Kushima, Takayuki Sasano, Masao Matsuoka, MD PhD, Hiroyuki Hata, MD PhD, Yawara Kawano, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1810.
https://doi.org/10.1182/blood-2019-123624
Published: 2019
Journal Articles

JX06, a Novel PDK1 Inhibitor, Induces Myeloma Cell Apoptosis By Metabolic Reprogramming and Works Synergistically with Bortezomib

Takayuki Sasano, Saki Kushima, Matsushita Yutaka, Masao Matsuoka, MD PhD, Hiroyuki Hata, MD PhD, Yawara Kawano, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1814.
https://doi.org/10.1182/blood-2019-123619
Published: 2019
Journal Articles

HTLV-1 Dysregulates IL-6 and IL-10-JAK/STAT Signaling and Induces Leukemia/Lymphoma of Mature CD4+ T Cells with Regulatory T-Cell-like Signatures

Yusuke Higuchi, MD, Jun-ichirou Yasunaga, MD PhD, Yu Mitagami, PhD, Koichi Ohshima, MD PhD, Masao Matsuoka, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1516.
https://doi.org/10.1182/blood-2019-125546
Published: 2019
Journal Articles

Targeting the Plasma Cell Specific Purine Metabolic Enzyme, AMPD1, Induces Multiple Myeloma Cell Death Accompanying NAD Depletion

Yawara Kawano, MD PhD, Takayuki Sasano, Saki Kushima, Yuki Inada, Nao Nishimura, MD, Hiroyuki Hata, MD PhD, Masao Matsuoka, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3097.
https://doi.org/10.1182/blood-2019-125756
Published: 2019
Journal Articles

Dynamic Changes of Chromatin Structure and Transcriptome By Transient Expression of HTLV-1 Tax in ATL Cells

Daisuke Kurita, MD PhD, Jun-ichirou Yasunaga, MD PhD, Azusa Tanaka, PhD, Mahgoub Mohamed, MD PhD, Masao Matsuoka, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4094.
https://doi.org/10.1182/blood-2018-99-111125
Published: 2018
Journal Articles

The Purine Metabolic Enzyme AMPD1 Is a Novel Therapeutic Target for Multiple Myeloma

Yawara Kawano, MD PhD, Yuki Inada, Takayuki Sasano, Nao Nishimura, MD, Hiroyuki Hata, MD PhD, Masao Matsuoka, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5614.
https://doi.org/10.1182/blood-2018-99-118603
Published: 2018
Journal Articles

Tax-Targeting Dendritic Cell Therapy for ATL: A Phase Ia/Ib Clinical Study

Motoaki Shiratsuchi, MDPhD, Tetsuya Fukuda, MD PhD, Tadafumi Iino, MD PhD, Atsuhiko Hasegawa, PhD, Jun-ichirou Yasunaga, MD PhD, Ken Watanabe, MD PhD, Akie Hirata, MD PhD, Hayato Utsunomiya, MD, Hirofumi Ohno, MD, Takashi Ishida, MD PhD, Koichi Akashi, MD PhD, Masao Matsuoka, MDPhD, Mari Kannagi, MD PhD, Youko Suehiro, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1649.
https://doi.org/10.1182/blood-2018-99-113315
Published: 2018
Journal Articles

Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma

Clinical Trials & Observations
Keisuke Kataoka, Masako Iwanaga, Jun-ichirou Yasunaga, Yasunobu Nagata, Akira Kitanaka, Takuro Kameda, Makoto Yoshimitsu, Yuichi Shiraishi, Aiko Sato-Otsubo, Masashi Sanada, Kenichi Chiba, Hiroko Tanaka, Yotaro Ochi, Kosuke Aoki, Hiromichi Suzuki, Yusuke Shiozawa, Tetsuichi Yoshizato, Yusuke Sato, Kenichi Yoshida, Kisato Nosaka, Masakatsu Hishizawa, Hidehiro Itonaga, Yoshitaka Imaizumi, Wataru Munakata, Kotaro Shide, Yoko Kubuki, Tomonori Hidaka, Tsuyoshi Nakamaki, Ken Ishiyama, Shuichi Miyawaki, Ryohei Ishii, Osamu Nureki, Kensei Tobinai, Yasushi Miyazaki, Akifumi Takaori-Kondo, Tatsuhiro Shibata, Satoru Miyano, Kenji Ishitsuka, Atae Utsunomiya, Kazuya Shimoda, Masao Matsuoka, Toshiki Watanabe, Seishi Ogawa
Journal: Blood
Blood (2018) 131 (2): 215–225.
https://doi.org/10.1182/blood-2017-01-761874
Published: 2018
Includes: Supplemental data
Journal Articles

Altered Expression of CCR10 Indicates Malignant Transformation of Bone Marrow Plasma Cells

Yawara Kawano, MD PhD, Misaki Kakoki, Yuki Inada, Nao Nishimura, MD, Yutaka Okuno, MD, PhD, Hiroyuki Hata, MDPhD, Masao Matsuoka, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1782.
https://doi.org/10.1182/blood.V130.Suppl_1.1782.1782
Published: 2017
Journal Articles

Clinicopathological Study of Methotrexate-Associated Lymphoproliferative Disorders in Rheumatoid Arthritis Patients: Histological Classification and Predictive Factors for Disease Progression

Daisuke Kurita, MD, Hiroaki Miyoshi, MDPhD, Ayako Ichikawa, MDPhD, Yuya Sasaki, MD, Keisuke Kawamoto, MDPhD, Joji Shimono, MD, Masao Matsuoka, MDPhD, Masahiro Kizaki, MDPhD, Masao Seto, MD PhD, Jun-ichi Tamaru, MDPhD, Michihide Tokuhira, MD, Koichi Ohshima, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4168.
https://doi.org/10.1182/blood.V130.Suppl_1.4168.4168
Published: 2017
Journal Articles

Hematopoietic Stem Cell Infected with HTLV-1 Functions As a Viral Reservoir In Vivo

Jun-ichirou Yasunaga, MDPhD, Rie Furuta, Michi Miura, Kenji Sugata, Akatsuki Saito, Akari Hirofumi, Takaharu Ueno, Norihiro Takenouchi, Jun-ichi Fujisawa, Masakazu Shimizu, Fumihiko Matsuda, MD PhD, Anat Melamed, Charles R. M. Bangham, Masao Matsuoka, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1343.
https://doi.org/10.1182/blood.V128.22.1343.1343
Published: 2016
Journal Articles

Functional Impairment of Co-Inhibitory Receptors Promotes T-Cell Proliferation in HTLV-1 Associated Adult T-Cell Leukemia Cells

Haruka Kinosada, Jun-ichirou Yasunaga, MDPhD, Kazuya Shimura, PhD, Masao Matsuoka, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2516.
https://doi.org/10.1182/blood.V128.22.2516.2516
Published: 2016