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Journal Articles

ADAR1-regulated cytoplasmic dsRNA-sensing pathway is a novel mechanism of lenalidomide resistance in multiple myeloma

Mun Yee Koh, Tae-Hoon Chung, Nicole Xin Ning Tang, Sabrina Hui Min Toh, Jianbiao Zhou, Tze King Tan, Leilei Chen, Wee Joo Chng, Phaik Ju Teoh
Journal: Blood
Blood blood.2024024429.
https://doi.org/10.1182/blood.2024024429
Published: 2024
Includes: Supplemental data
Journal Articles

Chronic active Epstein-Barr virus disease originates from infected hematopoietic stem cells

Clinical Trials & Observations
Jingshi Wang, Min Su, Na Wei, Huanyu Yan, Jia Zhang, Yi Gong, Lin Wu, Dina Suolitiken, Yubo Pi, Deli Song, Leilei Chen, Huan Liu, Shuo Yang, Xi Wang, Zhao Wang
Journal: Blood
Blood (2024) 143 (1): 32–41.
https://doi.org/10.1182/blood.2023021074
Published: 2024
Includes: Supplemental data
Journal Articles

Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis

Mingrui Guo, Tim Hon Man Chan, Qiling Zhou, Omer An, Ying Li, Yangyang Song, Zi Hui Tan, Vanessa Hui En Ng, Philomina Sona Peramangalam, Zhi Qing Tan, Xinang Cao, Eisaku Iwanaga, Masao Matsuoka, Melissa G. M. Ooi, Wei Ying Jen, Liang Piu Koh, Esther Chan, Lip Kun Tan, Yufen Goh, Wilson Wang, Bryan T. H. Koh, Chan Ming Chun, Melissa J. Fullwood, Wee Joo Chng, Motomi Osato, John Anto Pulikkan, Henry Yang, Leilei Chen, Daniel G. Tenen
Journal: Blood
Blood (2023) 141 (25): 3078–3090.
https://doi.org/10.1182/blood.2022015830
Published: 2023
Includes: Supplemental data
Journal Articles

Elucidating the Role of ADAR1 in Regulating Immunotherapeutic Response in Multiple Myeloma

Mun Yee Koh, Phaik Ju Teoh, Tae-Hoon Chung, Leilei Chen, Wee Joo Chng
Journal: Blood
Blood (2022) 140 (Supplement 1): 7084–7085.
https://doi.org/10.1182/blood-2022-158848
Published: 2022
Journal Articles

Potential IL6R-ADAR1-STAT3 Interplay Promotes Oncogenicity in 1q21(amp) Multiple Myeloma

Phaik Ju Teoh, PhD, Tae-Hoon Chung, Leilei Chen, PhD, Wee Joo Chng, MB ChB, PhD FRCP(UK), FRCPath, FAMS
Journal: Blood
Blood (2018) 132 (Supplement 1): 4513.
https://doi.org/10.1182/blood-2018-99-118895
Published: 2018
Journal Articles

Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis

Phaik Ju Teoh, Omer An, Tae-Hoon Chung, Jing Yuan Chooi, Sabrina H. M. Toh, Shuangyi Fan, Wilson Wang, Bryan T. H. Koh, Melissa J. Fullwood, Melissa G. Ooi, Sanjay de Mel, Cinnie Y. Soekojo, Leilei Chen, Siok Bian Ng, Henry Yang, Wee Joo Chng
Journal: Blood
Blood (2018) 132 (12): 1304–1317.
https://doi.org/10.1182/blood-2018-02-832576
Published: 2018
Includes: Supplemental data