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John Anto Pulikkan
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Journal Articles

GATA2-TAL1 Axis Is Essential for Human NK Cell Development and Function

Dandan Wang, Fangfei Zhang, Anthony Veltri, John Anto Pulikkan, Sridhar Rao, Subramaniam Malarkannan
Journal: Blood
Blood (2023) 142 (Supplement 1): 151.
https://doi.org/10.1182/blood-2023-191027
Published: 2023
Journal Articles

Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis

Mingrui Guo, Tim Hon Man Chan, Qiling Zhou, Omer An, Ying Li, Yangyang Song, Zi Hui Tan, Vanessa Hui En Ng, Philomina Sona Peramangalam, Zhi Qing Tan, Xinang Cao, Eisaku Iwanaga, Masao Matsuoka, Melissa G. M. Ooi, Wei Ying Jen, Liang Piu Koh, Esther Chan, Lip Kun Tan, Yufen Goh, Wilson Wang, Bryan T. H. Koh, Chan Ming Chun, Melissa J. Fullwood, Wee Joo Chng, Motomi Osato, John Anto Pulikkan, Henry Yang, Leilei Chen, Daniel G. Tenen
Journal: Blood
Blood (2023) 141 (25): 3078–3090.
https://doi.org/10.1182/blood.2022015830
Published: 2023
Includes: Supplemental data
Journal Articles

Differential Engraftment of CEBPA Mutated Acute Myeloid Leukemia Cells in NSGS Mice

Philomina Sona Peramangalam, Sridevi Surapally, Sridhar Rao, Carsten Müller-Tidow, John Anto Pulikkan
Journal: Blood
Blood (2022) 140 (Supplement 1): 12655–12656.
https://doi.org/10.1182/blood-2022-170448
Published: 2022
Journal Articles

MYCN Regulates Cell Survival Via EIF4G1 in Inv(16) Acute Myeloid Leukemia

Philomina Sona Peramangalam, Sridevi Surapally, Shikan Zheng, Robert Burns, Nan Zhu, Sridhar Rao, Carsten Müller-Tidow, John Anto Pulikkan
Journal: Blood
Blood (2022) 140 (Supplement 1): 9117–9118.
https://doi.org/10.1182/blood-2022-170112
Published: 2022
Journal Articles

CBFβ-SMMHC Inhibition Disrupts Enhancer Chromatin Dynamics and Represses MYC Transcriptional Program in Inv(16) Leukemia

John Anto Pulikkan, PhD, Mahesh Hegde, Houda Belaghzal, Anuradha Illendula, Jun Yu, Hafiz Ahmed, Kelsey O'Hagen, Jianhong Ou, Carsten Müller-Tidow, Scot A. Wolfe, Julie Zhu, Job Dekker, John H. Bushweller, Lucio H. Castilla
Journal: Blood
Blood (2017) 130 (Supplement 1): 784.
https://doi.org/10.1182/blood.V130.Suppl_1.784.784
Published: 2017
Journal Articles

Selective Inhibition of the Leukemia Fusion Protein CBFβ-SMMHC By Small Molecule AI-10-49 in the Treatment of Inv(16) AML

John Anto Pulikkan, PhD, Anuradha Illendula, PhD, Jolanta Grembecka, Liting Xue, Roger Rajewski, Monica L. Guzman, PhD, John H. Bushweller, PhD, Lucio H. Castilla, PhD
Journal: Blood
Blood (2014) 124 (21): 390.
https://doi.org/10.1182/blood.V124.21.390.390
Published: 2014
Journal Articles

Deletion Of Core Binding Factors Runx1 and Runx2 Leads To Perturbed Hematopoiesis In Multiple Lineages

John Anto Pulikkan, PhD, Xue Liting, Rachel Gerstein, PhD, Merav Socolovsky, PhD, Lucio H. Castilla, PhD
Journal: Blood
Blood (2013) 122 (21): 46.
https://doi.org/10.1182/blood.V122.21.46.46
Published: 2013
Journal Articles

A Small Molecule Inhibitor of the CBFβ-SMMHC/RUNX Interaction Attenuates Inv(16) Leukemia in Vivo

John H. Bushweller, PhD, Anuradha Illendula, Ph.D., John Anto Pulikkan, Jolanta Grembecka, PhD, Paul Bradley, Yunpeng Zhou, Ph.D., Liting Xue, Yan Gao, Lucio H. Castilla, PhD
Journal: Blood
Blood (2012) 120 (21): 286.
https://doi.org/10.1182/blood.V120.21.286.286
Published: 2012
Journal Articles

Thrombopoietin/MPL participates in initiating and maintaining RUNX1-ETO acute myeloid leukemia via PI3K/AKT signaling

John Anto Pulikkan, Dmitri Madera, Liting Xue, Paul Bradley, Sean Francis Landrette, Ya-Huei Kuo, Saman Abbas, Lihua Julie Zhu, Peter Valk, Lucio Hernán Castilla
Journal: Blood
Blood (2012) 120 (4): 868–879.
https://doi.org/10.1182/blood-2012-03-414649
Published: 2012
Includes: Supplemental data
Journal Articles

The Interplay Between Microrna-223 and E2F1 Regulates Cell Cycle Control During Granulopoiesis.

John Anto Pulikkan, Viola Dengler, Philomina Sona Peramangalam, Abdul A. Peer Zada, Carsten Müller tidow, Stefan K Bohlander, Daniel G. Tenen, MD, Gerhard Behre, MD
Journal: Blood
Blood (2009) 114 (22): 255.
https://doi.org/10.1182/blood.V114.22.255.255
Published: 2009
Journal Articles

A Molecular Network Comprising MicroRNA-223, E2F1 and C/Ebpα in Granulopoiesis and in Acute Myeloid Leukemia.

John Anto Pulikkan, Viola Dengler, Abdul Peerzada, Stefan Bohlander, MD, Daniel G. Tenen, MD, Gerhard Behre
Journal: Blood
Blood (2008) 112 (11): 1803.
https://doi.org/10.1182/blood.V112.11.1803.1803
Published: 2008
Journal Articles

PIN1 Blocks Granulocytic Differentiation Via C-Jun in Acute Myeloid Leukemia with CEBPA Mutations.

John Anto Pulikkan, Viola Dengler, Abdul Peerzada, Stefan Bohlander, MD, Daniel G. Tenen, MD, Gerhard Behre
Journal: Blood
Blood (2008) 112 (11): 1205.
https://doi.org/10.1182/blood.V112.11.1205.1205
Published: 2008
Journal Articles

Significant Role of Peptidyl-Prolyl cis/trans Isomerase, Pin1 in Acute Myeloid Leukemia with C/EBPα Mutations.

John Anto Pulikkan, MSc, Viola Dengler, MSc, Abdul A. Peer Zada, PhD, Mulu Gelutu, PhD, Daniel G. Tenen, MD, Gerhard Behre, MD
Journal: Blood
Blood (2007) 110 (11): 55.
https://doi.org/10.1182/blood.V110.11.55.55
Published: 2007