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Journal Articles

Selective Inhibition of the Leukemia Fusion Protein CBFβ-SMMHC By Small Molecule AI-10-49 in the Treatment of Inv(16) AML

John Anto Pulikkan, PhD, Anuradha Illendula, PhD, Jolanta Grembecka, Liting Xue, Roger Rajewski, Monica L. Guzman, PhD, John H. Bushweller, PhD, Lucio H. Castilla, PhD
Journal: Blood
Blood (2014) 124 (21): 390.
https://doi.org/10.1182/blood.V124.21.390.390
Published: 2014
Journal Articles

PKC Pathways Mediate BCR-ABL-Independent Imatinib Resistance in Chronic Myeloid Leukemia

Leyuan Ma, Yi Shan, Robert Bai, Liting Xue, Christopher A. Eide, Jianhong Ou, Lihua J. Zhu, Lloyd Hutchinson, PhD, Jan Cerny, MD PhD, H. Jean Khoury, MD, Zhi Sheng, Brian J. Druker, Shaoguang Li, MD PhD, Michael Green
Journal: Blood
Blood (2014) 124 (21): 1790.
https://doi.org/10.1182/blood.V124.21.1790.1790
Published: 2014
Journal Articles

Nras G12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis

Liting Xue, John A. Pulikkan, Peter J. M. Valk, Lucio H. Castilla
Journal: Blood
Blood (2014) 124 (3): 426–436.
https://doi.org/10.1182/blood-2013-12-541730
Published: 2014
Includes: Supplemental data
Journal Articles

A Small Molecule Inhibitor of the CBFβ-SMMHC/RUNX Interaction Attenuates Inv(16) Leukemia in Vivo

John H. Bushweller, PhD, Anuradha Illendula, Ph.D., John Anto Pulikkan, Jolanta Grembecka, PhD, Paul Bradley, Yunpeng Zhou, Ph.D., Liting Xue, Yan Gao, Lucio H. Castilla, PhD
Journal: Blood
Blood (2012) 120 (21): 286.
https://doi.org/10.1182/blood.V120.21.286.286
Published: 2012
Journal Articles

Thrombopoietin/MPL participates in initiating and maintaining RUNX1-ETO acute myeloid leukemia via PI3K/AKT signaling

John Anto Pulikkan, Dmitri Madera, Liting Xue, Paul Bradley, Sean Francis Landrette, Ya-Huei Kuo, Saman Abbas, Lihua Julie Zhu, Peter Valk, Lucio Hernán Castilla
Journal: Blood
Blood (2012) 120 (4): 868–879.
https://doi.org/10.1182/blood-2012-03-414649
Published: 2012
Includes: Supplemental data