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Wee Joo Chng
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Journal Articles

ADAR1-regulated cytoplasmic dsRNA-sensing pathway is a novel mechanism of lenalidomide resistance in multiple myeloma

Mun Yee Koh, Tae-Hoon Chung, Nicole Xin Ning Tang, Sabrina Hui Min Toh, Jianbiao Zhou, Tze King Tan, Leilei Chen, Wee Joo Chng, Phaik Ju Teoh
Journal: Blood
Blood blood.2024024429.
https://doi.org/10.1182/blood.2024024429
Published: 2024
Includes: Supplemental data
Journal Articles

Characteristics and Outcomes of Acute Myeloid Leukemia in Ethnically Diverse Asians in Singapore

Natasha Fay Anthony, Yen-Lin Chee, Pak Ling Lui, Esther Chan, Michelle Poon, Lip Kun Tan, Jameelah Binte Sekh Mohamed, Liang Piu Koh, Melissa G OOI, Wee-Joo Chng, Wei-Ying Jen
Journal: Blood
Blood (2024) 144 (Supplement 1): 7899.
https://doi.org/10.1182/blood-2024-198845
Published: 2024
Journal Articles

Machine Learning Classification of Spatial Patterns of Malignant Cells Reveals Implications in Prognosis and Tumor Microenvironment Composition in Lymphoma

Shruti Sridhar, Michal Marek Hoppe, Patrick Jaynes, Gayatri Kumar, Siddham Jasoria, Ziwei Meng, Yanfen Peng, Sanjay De Mel, Limei Poon, Esther Hian Li Chan, Wee-Joo Chng, Soo Yong Tan, Susan Swee-Shan Hue, Siok-Bian Ng, Chandramouli Nagarajan, Nicholas Francis Grigoropoulos, Shaoying Li, Joseph D. Khoury, Pedro Farinha, Anja Mottok, David W. Scott, Xiaofei Ye, Qiang Pan-Hammarström, Vaibhav Rajan, Kasthuri Kannan, Anand Devaprasath D. Jeyasekharan
Journal: Blood
Blood (2024) 144 (Supplement 1): 3602.
https://doi.org/10.1182/blood-2024-209372
Published: 2024
Journal Articles

Frequent Copy Gains of Viral LMP-1 Confers Radiosensitivity in Natural-Killer/T Cell Lymphoma

Jing Quan Lim, Dachuan Huang, Kelila Xin Ye Chai, Phyu The, Kerry May Huifen Lim, Wendy Lee, Liang Wei Wang, Nur Ayuni Muhammad Taib, Beng Hooi Phang, Wee-Joo Chng, Olaf Rötzschke, Jason Yongsheng Chan, Soon Thye Lim, Jin-Xin BEI, Siok-Bian Ng, Choon Kiat Ong
Journal: Blood
Blood (2024) 144 (Supplement 1): 2963.
https://doi.org/10.1182/blood-2024-192976
Published: 2024
Journal Articles

Spatial-Resolved Transcriptomics Reveals Immune Landscape Variations in Primary Central Nervous System Lymphoma (PCNSL) and Diffuse Large B-Cell Lymphoma (DLBCL)

Min Liu, Liang Hong, Shruti Sridhar, Patrick Jaynes, Chartsiam Tipgomut, Limei Poon, Sanjay De Mel, Joanne Shu Xian Lee, Jayalakshmi, Siok-Bian Ng, Char Loo Tan, Wee-Joo Chng, Anand Devaprasath D. Jeyasekharan
Journal: Blood
Blood (2024) 144 (Supplement 1): 3004.
https://doi.org/10.1182/blood-2024-209497
Published: 2024
Journal Articles

Evaluating the Comprehensive Geriatric Assessment Model As an Assessment Tool to Predict Chemotoxicity in Elderly Patients with Lymphoma

Xinjie Jonathan Tang, Joanne Shu Xian Lee, Esther Hian Li Chan, Sanjay De Mel, Yen-Lin Chee, Wee-Joo Chng, Michelle Limei Poon, Shi Hui Clarice Choong, Melissa Gaik-Ming Ooi
Journal: Blood
Blood (2024) 144 (Supplement 1): 388.
https://doi.org/10.1182/blood-2024-198867
Published: 2024
Journal Articles

Proliferative CD8 T-Cells: A Novel Immune Microenvironmental Determinant of Outcomes in Multiple Myeloma with Translocation (4;14)

Sanjay De Mel, Jonathan Scolnick, Chern Han Yong, Stacy Li Wen Xu, Xiaojing Huo, Cinnie Soekojo, Fang Fang Song, Melissa G Ooi, Phyu The, Radhika Sharma, Yanfen Peng, Sabrina Toh, Siok-Bian Ng, Anand Devaprasath Jeyasekharan, Joe Yeong, Li Yen Chong, Chi Ching Lim, Felicia Wee, Jinmiao Chen, Lim Soon Wong, Jun Siong Low, Wee-Joo Chng
Journal: Blood
Blood (2024) 144 (Supplement 1): 1950.
https://doi.org/10.1182/blood-2024-198769
Published: 2024
Journal Articles

Outcomes of Elderly Patients with DLBCL and Utility of Geriatric Assessment Tools to Predict Chemotoxicity

Xinjie Jonathan Tang, Joanne Shu Xian Lee, Esther Hian Li Chan, Sanjay De Mel, Yen-Lin Chee, Wee-Joo Chng, Nicole-Ann Lim, Jason Yongsheng Chan, Soon Thye Lim, Shi Hui Clarice Choong, Melissa Gaik-Ming Ooi, Michelle Limei Poon
Journal: Blood
Blood (2024) 144 (Supplement 1): 3660.
https://doi.org/10.1182/blood-2024-208906
Published: 2024
Journal Articles

Real World Evidence of Outcomes of Patients Treated with Talquetamab in a Heavily Pretreated Population with Multiple Myeloma with High Exposure to Prior BCMA Therapies- a Report from the IMWG Consortium

Murali Janakiram, Carlyn Rose Tan, Rakesh Popat, Joaquín Martínez Lopez, Efstathios Kastritis, Chris Lau, Wee-Joo Chng, Prashant Kapoor, Hira Mian, Susan Bal, Ajay K. Nooka, Andre De Menezes Silva Corraes, Magdalena Corona, Arnab Chowdhury, Yi Lin, Thomas G Martin, Amrita Y Krishnan
Journal: Blood
Blood (2024) 144 (Supplement 1): 3368.
https://doi.org/10.1182/blood-2024-211167
Published: 2024
Journal Articles

The c-MAF/SLP76 Axis Modulates Immune Evasion and Drives Malignancy in Multiple Myeloma Via Epigenetic Reprogramming

Zhenfeng Dai, Yunlu Jia, Jianbiao Zhou, Wee-Joo Chng, Zhen Cai
Journal: Blood
Blood (2024) 144 (Supplement 1): 3277.
https://doi.org/10.1182/blood-2024-206958
Published: 2024
Journal Articles

An Entirely Oral Regimen of Oral-Arsenic Trioxide/All-Trans Retinoic Acid/Ascorbic Acid in Newly-Diagnosed Acute Promyelocytic Leukaemia (APL): Updated Results of an Ongoing Multicentre Trial

Harinder Gill, Rita Yim, Lynn Chin, Paul Lee, Vivian Li, Lester Au, Garret Man Kit Leung, Ka Leung Daniel Cheuk, Shau-Yin Ha, Chi Kong Li, Melissa Ooi, Wee-Joo Chng, Patrick Chu, Cyrus Kumana, Yok Lam Kwong
Journal: Blood
Blood (2023) 142 (Supplement 1): 157.
https://doi.org/10.1182/blood-2023-179644
Published: 2023
Journal Articles

A Prospective, Multinational Study of Clinical and Biological Factors Associated with Short Overall Survival in Multiple Myeloma

Andy Tang, Kihyun Kim, Fiona Chen, Zoe K McQuilten, Peter Mollee, Rajeev Rajagopal, Hang Quach, Phoebe Joy Ho, Simon J. Harrison, Andrew Spencer, Wee-Joo Chng
Journal: Blood
Blood (2023) 142 (Supplement 1): 4731.
https://doi.org/10.1182/blood-2023-178192
Published: 2023
Journal Articles

Targeting Mitochondrial Apoptotic Priming State to Personalize Therapy for Relapsed Acute Myeloid Leukemia

Elyse Olesinski, Karanpreet Bhatia, Chuqi Wang, Marissa Pioso, Shu Xuan Ng, Xiao Xian Lin, Vedant Sandhu, Binyam Yilma, Stephan Rainer Maximilian Bohl, Jeremy Ryan, Disha Malani, Marlise R. Luskin, Olli Kallioniemi, Kimmo Porkka, Allen Yeoh, Sophia Adamia, Wee Joo Chng, Motomi Osato, David M. Weinstock, Jacqueline S. Garcia, Anthony G. Letai, Shruti Bhatt
Journal: Blood
Blood (2023) 142 (Supplement 1): 48.
https://doi.org/10.1182/blood-2023-189156
Published: 2023
Journal Articles

Randomized Phase 3 Study of Pomalidomide Cyclophosphamide Dexamethasone (PCD) Versus Pomalidomide Dexamethasone (PD) in Relapse or Refractory Myeloma: An Asian Myeloma Network (AMN) Study

Yang Song, Jin Seok Kim, CS Chim, Je-Jung Lee, Sung-Soo Yoon, Soo Chin Ng, Gin Gin Gan, Hiroshi Handa, Wei-Ying Jen, Xinhua Li, Yogesh Mahadev Pokharkar, Brian GM Durie, Wee-Joo Chng
Journal: Blood
Blood (2023) 142 (Supplement 1): 1009.
https://doi.org/10.1182/blood-2023-184723
Published: 2023
Journal Articles

Development of a Novel Artificial Intelligence Tool to Measure Psoas Volumes in Patients with Diffuse Large B Cell Lymphoma

Edwin Wei Sheng Thong, Andrew Makmur, Yen-Lin Chee, James Hallihan, Lenith Tai Jit Cheng, Nesaretnam Barr Kumarakulasinghe, Anand Devaprasath Jeyasekharan, Joanne Shu Xian Lee, Sanjay De Mel, Esther Hian Li Chan, Michelle Poon, Wee-Joo Chng, Jayalakshmi ., Melati Dewi Ali, Wei-Ying Jen, Desmond Shi Wei Lim
Journal: Blood
Blood (2023) 142 (Supplement 1): 3652.
https://doi.org/10.1182/blood-2023-178239
Published: 2023
Journal Articles

Daratumumab Bortezomib and Dexamethasone in Transplant Ineligible Newly Diagnosed Elderly Myeloma Patients - a Trial By Asian Myeloma Network

Chandramouli Nagarajan, Melinda Tan, Yunxin Chen, Melissa Ooi, Sanjay De Mel, Allison Tso, Lawrence Ng, Hein Than, Yeow Tee Goh, Brian GM Durie, Wee-Joo Chng
Journal: Blood
Blood (2023) 142 (Supplement 1): 6721.
https://doi.org/10.1182/blood-2023-173476
Published: 2023
Journal Articles

Novel Protac-Based EZH2 Degraders Effectively Target EZH2-Driven Lymphoid Malignancies By Abolishing Both Methylation-Dependent and -Independent Functions

Nurulhuda Mustafa, Zubaida Talal Alnaseri, Darrel Egk Jian Tan, Irfan Azaman, David Thanh Truong Quach, Wan Hsin Lim, Wee-Joo Chng
Journal: Blood
Blood (2023) 142 (Supplement 1): 4183.
https://doi.org/10.1182/blood-2023-190382
Published: 2023
Journal Articles

A Phase 2 Study of Daratumumab in Combination with Thalidomide and Dexamethasone in Relapsed and / or Refractory Myeloma: A Report from the Asian Myeloma Network

Wei-Ying Jen, Melissa Ooi, Sanjay De Mel, Cinnie Soekojo, Sung-Soo Yoon, Xinhua Li, Neha Awasthi, Sarah M Burkill, Brian GM Durie, Wee-Joo Chng
Journal: Blood
Blood (2023) 142 (Supplement 1): 2009.
https://doi.org/10.1182/blood-2023-180017
Published: 2023
Journal Articles

Extracellular Vesicles Secreted from Daratumumab Resistant Cells Promote Resistance and Proliferation of Daratumumab Sensitive Cells, Possibly through the Transfer of miRNA Cargo

Irfan Azaman, Wee-Joo Chng, Nurulhuda Mustafa, Sanjay De Mel
Journal: Blood
Blood (2023) 142 (Supplement 1): 1443.
https://doi.org/10.1182/blood-2023-185134
Published: 2023
Journal Articles

Impact of 1q21 Gain and Amplification on Daratumumab-Treated Multiple Myeloma Patients: Real-World Data from the Australia-New Zealand and Asia-Pacific Myeloma and Related Diseases Registries

Kenneth J C Lim, Cameron Wellard, Elizabeth Moore, Slavisa Ninkovic, Wee-Joo Chng, Andrew Spencer, Peter Mollee, Jay Hocking, Phoebe Joy Ho, Wojt Janowski, Kihyun Kim, Karen Dun, Zoe K McQuilten, Fiona Chen, Hang Quach
Journal: Blood
Blood (2023) 142 (Supplement 1): 3325.
https://doi.org/10.1182/blood-2023-173896
Published: 2023