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Darren Qiancheng Tan
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Journal Articles

Loss of METTL3 Attenuates BPDCN Response to PRMT5 Inhibition Via Interferon Signaling

Malini Rethnam, Darren Qiancheng Tan, Shi Hao Tan, Li Ying, Henry Yang, Toshio Suda
Journal: Blood
Blood (2021) 138 (Supplement 1): 1132.
https://doi.org/10.1182/blood-2021-146108
Published: 2021
Journal Articles

Prolonged maintenance of hematopoietic stem cells that escape from thrombopoietin deprivation

Ayako Nakamura-Ishizu, Desmond Wai Loon Chin, Takayoshi Matsumura, Darren Qiancheng Tan, Makiko Mochizuki-Kashio, Deng Jianwen, Toshio Suda
Journal: Blood
Blood (2021) 137 (19): 2609–2620.
https://doi.org/10.1182/blood.2020005517
Published: 2021
Includes: Supplemental data
Journal Articles

PRMT5 Inhibition Affects RNA Methylation and Is a Potential Therapeutic Target in BPDCN

Malini Rethnam, Darren Qiancheng Tan, PhD, Shi Hao Tan, PhD, Li Ying, Henry Yang, PhD, Toshio Suda, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13.
https://doi.org/10.1182/blood-2020-133352
Published: 2020
Journal Articles

Hematopoietic stem cells acquire survival advantage by loss of RUNX1 methylation identified in familial leukemia

Clinical Trials & Observations
Takayoshi Matsumura, Ayako Nakamura-Ishizu, Siva Sai Naga Anurag Muddineni, Darren Qiancheng Tan, Chelsia Qiuxia Wang, Kenji Tokunaga, Roberto Tirado-Magallanes, Stephanie Sian, Touati Benoukraf, Tsukasa Okuda, Norio Asou, Masao Matsuoka, Motomi Osato, Toshio Suda
Journal: Blood
Blood (2020) 136 (17): 1919–1932.
https://doi.org/10.1182/blood.2019004292
Published: 2020
Includes: Supplemental data
Journal Articles

Genetic Ablation or Pharmacological Inhibition of PRMT5 Affects Maintenance of Genomic Integrity in Hematopoietic Stem Cells

Darren Qiancheng Tan, BS, Desmond Wai Loon Chin, PhD, Ying Li, Ayako Nakamura-Ishizu, MD PhD, Henry Yang, PhD, Toshio Suda, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 711.
https://doi.org/10.1182/blood.V130.Suppl_1.711.711
Published: 2017