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Journal Articles

Integrated Analysis of KIT Exon 17 Mutations and Flow-MRD Refines Risk Stratification in Pediatric Acute Myeloid Leukemia with RUNX1 :: RUNX1T1

Shin-Ichi Tsujimoto, Shota Kato, Shotaro Iwamoto, Hidefumi Hiramatsu, Yusuke Okuno, Tatsuya Kamitori, Kentaro Ohki, Takao Deguchi, Nobutaka Kiyokawa, Motohiro Kato, Junko Takita, Souichi Adachi, Daisuke Tomizawa, Norio Shiba

Blood (2023) 142 (Supplement 1): 1599.

https://doi.org/10.1182/blood-2023-181358

Published: 2023

Journal Articles

Label-Free Cell Detection of Acute Leukemia Using High-Content Morphological Profiling in Flow

Yoko Kawamura, Kayoko Nakanishi, Yuri Murata, Kazuki Teranishi, Ryusuke Miyazaki, Keisuke Toda, Toru Imai, Yasuhiro Kajiwara, Keiji Nakagawa, Hidemasa Matsuo, Souichi Adachi, Sadao Ota, Hidefumi Hiramatsu

Blood (2023) 142 (Supplement 1): 906.

https://doi.org/10.1182/blood-2023-188914

Published: 2023

Journal Articles

IL-4 Acts at an Early Fate-Determining Junction in Hematopoiesis to Induce NK Cell Subsets Expressing Endogenous CD16

Saori Nakano, Akira Niwa, Yohko Kitagawa, Hidefumi Hiramatsu, Megumu K Saito

Blood (2023) 142 (Supplement 1): 1.

https://doi.org/10.1182/blood-2023-188768

Published: 2023

Journal Articles

Evaluation of High-Dose Cytarabine Induction Therapy and Flow Cytometric Measurable Residual Disease Monitoring for Children with De Novo Acute Myeloid Leukemia: A Report from the JPLSG-AML-12 Trial

Blood (2022) 140 (Supplement 1): 1450–1452.

https://doi.org/10.1182/blood-2022-158664

Published: 2022

Journal Articles

Mass Cytometric Analysis Revealed Dynamic Alteration of the Tumor Immune Environment in Bone Marrow from Children with Recurrent B Cell Precursor Acute Lymphoblastic Leukemia

Blood (2021) 138 (Supplement 1): 2390.

https://doi.org/10.1182/blood-2021-146420

Published: 2021

Journal Articles

Chemotherapy with the Use of TKIs Based on MRD Has the Potential to Avoid Hematopoietic Stem Cell Transplantation in Treatment for Children with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ALL). Results of the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) Study ALL-Ph13

Atsushi Sato, Hirohide Kawasaki, Takao Deguchi, Yoshiko Hashii, Yuka Iijima-Yamashita, Sachiko Yonezawa, Chiyo K Imamura, Haruko Shima, Hirotoshi Sakaguchi, Yuichi Kodama, Keisuke Kato, Motohiro Kato, Hidefumi Hiramatsu, Nobutaka Kiyokawa, Akiko Kada, Akiko M Saito, Keizo Horibe, Atsushi Manabe, Hiroyuki Shimada

Blood (2021) 138 (Supplement 1): 3394.

https://doi.org/10.1182/blood-2021-148264

Published: 2021

Journal Articles

Post-Induction Minimal Residual Disease Measured By Flow Cytometry and Deep Sequencing of Mutant GATA1 Are Both Significant Prognostic Factors for Children with Myeloid Leukemia and Down Syndrome: A Nationwide Prospective Study of the Japanese Pediatric Leukemia/Lymphoma Study Group

Blood (2019) 134 (Supplement_1): 3848.

https://doi.org/10.1182/blood-2019-123302

Published: 2019

Journal Articles

Therapeutic Targeting of RUNX-NFATC2 Axis for Acute Promyelocytic Leukemia and T Cell Immunity

Hirohito Kubota, MD, Kana Furuichi, Tatsuya Masuda, Toshiya Tatsuta, Hidefumi Hiramatsu, MD PhD, Junko Takita, MD PhD, Sugiyama Hiroshi, PhD, Souichi Adachi, MD PhD, Yasuhiko Kamikubo, MD, PhD

Blood (2019) 134 (Supplement_1): 3359.

https://doi.org/10.1182/blood-2019-126428

Published: 2019

Journal Articles

Piggybac CD19 CAR T Cells Eradicate CNS Leukemia By Direct Delivery into Cerebral Ventricle of Xenograft Mice Model

Kuniaki Tanaka, MD, Itaru Kato, MD, PhD, Miyuki Tanaka, MD, PhD, Daisuke Morita, MD, PhD, Yoshiyuki Takahashi, MD, PhD, Tatsutoshi Nakahata, MD, PhD, Katsutsugu Umeda, MD, PhD, Hidefumi Hiramatsu, MD, PhD, Souichi Adachi, MD PhD, Junko Takita, MD, PhD, Yozo Nakazawa, MD, PhD

Blood (2018) 132 (Supplement 1): 4028.

https://doi.org/10.1182/blood-2018-99-111733

Published: 2018

Journal Articles

Updated Analysis of the Efficacy and Safety of Tisagenlecleucel in Pediatric and Young Adult Patients with Relapsed/Refractory (r/r) Acute Lymphoblastic Leukemia

Blood (2018) 132 (Supplement 1): 895.

https://doi.org/10.1182/blood-2018-99-112599

Published: 2018

Journal Articles

Molecular Detection of Minimal Residual Disease Precedes Morphological Relapse and Could be Used to Identify Relapse in Pediatric and Young Adult B-Cell Acute Lymphoblastic Leukemia Patients Treated with Tisagenlecleucel

Blood (2018) 132 (Supplement 1): 1551.

https://doi.org/10.1182/blood-2018-99-115460

Published: 2018

Journal Articles

Management of Coagulopathy Associated with CTL019 CAR T-Cell Therapy

Jochen Büchner, MDPhD, Stephan A Grupp, MD PhD, Shannon L Maude, MD PhD, Hidefumi Hiramatsu, MD PhD, David T Teachey, MD, Patricia A Wood, MD PhD, Rakesh Awasthi, PhD, Lan Yi, PhD, Barbara De Moerloose, MD PhD

Blood (2017) 130 (Supplement 1): 1276.

https://doi.org/10.1182/blood.V130.Suppl_1.1276.1276

Published: 2017

Journal Articles

CTL019 Therapy Appears Safe and Effective in Pediatric Patients with Down Syndrome with Relapsed/ Refractory (r/r) Acute Lymphoblastic Leukemia

Theodore W Laetsch, MD, Shannon L Maude, MD PhD, Stephan A Grupp, MD PhD, Michael W Boyer, MD, Andrew C Harris, MD, Muna Qayed, MDMSc, Christine L Phillips, MD, Michael A Pulsipher, MD, Henrique Bittencourt, MD PhD, Patricia A Wood, MD PhD, Karen Thudium Mueller, PharmD,MSc, Yanqui Weng, PhD, Carl H June, MD, Bruce L Levine, PhD, Hidefumi Hiramatsu, MD PhD

Blood (2017) 130 (Supplement 1): 1280.

https://doi.org/10.1182/blood.V130.Suppl_1.1280.1280

Published: 2017

Journal Articles

Low Incidence of Osteonecrosis in Childhood Acute Lymphoblastic Leukemia Treated with ALL-97 and ALL-02 Study of Japan Association of Childhood Leukemia Study Group

Blood (2017) 130 (Supplement 1): 1286.

https://doi.org/10.1182/blood.V130.Suppl_1.1286.1286

Published: 2017

Journal Articles

Analysis of a Global Registration Trial of the Efficacy and Safety of CTL019 in Pediatric and Young Adults with Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL)

Blood (2016) 128 (22): 221.

https://doi.org/10.1182/blood.V128.22.221.221

Published: 2016

Journal Articles

Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome

Blood (2013) 121 (21): 4377–4387.

https://doi.org/10.1182/blood-2012-12-474387

Published: 2013

Includes: Supplemental data

Journal Articles

Reduced Production of Mature Neutrophils From Induced Pluripotent Stem Cells Derived From a Severe Congenital Neutropenia Patient with HAX1 Gene Deficiency

Tatsuya Morishima, MD, Ken-ichiro Watanabe, MD, PhD, Akira Niwa, MD, PhD, Takayuki Tanaka, MD, Katsutsugu Umeda, MD, PhD, Hidefumi Hiramatsu, MD, PhD, Kousaku Matsubara, MD, PhD, Souichi Adachi, MD, PhD, Tatsutoshi Nakahata, MD, PhD, Toshio Heike, MD, PhD

Blood (2011) 118 (21): 2402.

https://doi.org/10.1182/blood.V118.21.2402.2402

Published: 2011

Journal Articles

Establishment of a Novel CNS Infiltrated Xenograft Model through Engraftment of Patient-Derived Acute Lymphoblastic Leukemic Cells Into NOD/SCID/γc Null Mouse

Itaru Kato, Akira Niwa, Megumu Saito, Hisanori Fujino, Satoshi Saida, Hidefumi Hiramatsu, Koichi Oshima, Mamoru Ito, Souichi Adachi, MD, PhD, Toshio Heike, MD, Tatsutoshi Nakahata, MD

Blood (2010) 116 (21): 3248.

https://doi.org/10.1182/blood.V116.21.3248.3248

Published: 2010

Journal Articles

Enriched MicroRNA-126 Bioactivity Marks the Primitive Compartment In AML and Regulates LSC Numbers

Eric Lechman, PhD, Bernhard Gentner, MD, Hidefumi Hiramatsu, MD, Kristin J Hope, PhD, Katsuto Takenaka, MD, Kolja Eppert, PhD, Mark D. Minden, MD, PhD, Luigi Naldini, MD, PhD, John E. Dick, PhD

Blood (2010) 116 (21): 94.

https://doi.org/10.1182/blood.V116.21.94.94

Published: 2010

Journal Articles

Identification and Function of Hematopoietic Stem and Progenitor Cell Specific Micrornas.

Bernhard Gentner, Alice Giustacchini, Francesco Boccalatte, Giulia Schira, Massimo Saini, Eric Lechman, Hidefumi Hiramatsu, John E. Dick, PhD, Luigi Naldini

Blood (2010) 116 (21): 2631.

https://doi.org/10.1182/blood.V116.21.2631.2631

Published: 2010

NARROW

Integrated Analysis of KIT Exon 17 Mutations and Flow-MRD Refines Risk Stratification in Pediatric Acute Myeloid Leukemia with RUNX1 :: RUNX1T1

Label-Free Cell Detection of Acute Leukemia Using High-Content Morphological Profiling in Flow

IL-4 Acts at an Early Fate-Determining Junction in Hematopoiesis to Induce NK Cell Subsets Expressing Endogenous CD16

Evaluation of High-Dose Cytarabine Induction Therapy and Flow Cytometric Measurable Residual Disease Monitoring for Children with De Novo Acute Myeloid Leukemia: A Report from the JPLSG-AML-12 Trial

Mass Cytometric Analysis Revealed Dynamic Alteration of the Tumor Immune Environment in Bone Marrow from Children with Recurrent B Cell Precursor Acute Lymphoblastic Leukemia

Post-Induction Minimal Residual Disease Measured By Flow Cytometry and Deep Sequencing of Mutant GATA1 Are Both Significant Prognostic Factors for Children with Myeloid Leukemia and Down Syndrome: A Nationwide Prospective Study of the Japanese Pediatric Leukemia/Lymphoma Study Group

Therapeutic Targeting of RUNX-NFATC2 Axis for Acute Promyelocytic Leukemia and T Cell Immunity

Piggybac CD19 CAR T Cells Eradicate CNS Leukemia By Direct Delivery into Cerebral Ventricle of Xenograft Mice Model

Updated Analysis of the Efficacy and Safety of Tisagenlecleucel in Pediatric and Young Adult Patients with Relapsed/Refractory (r/r) Acute Lymphoblastic Leukemia

Molecular Detection of Minimal Residual Disease Precedes Morphological Relapse and Could be Used to Identify Relapse in Pediatric and Young Adult B-Cell Acute Lymphoblastic Leukemia Patients Treated with Tisagenlecleucel

Management of Coagulopathy Associated with CTL019 CAR T-Cell Therapy

CTL019 Therapy Appears Safe and Effective in Pediatric Patients with Down Syndrome with Relapsed/ Refractory (r/r) Acute Lymphoblastic Leukemia

Low Incidence of Osteonecrosis in Childhood Acute Lymphoblastic Leukemia Treated with ALL-97 and ALL-02 Study of Japan Association of Childhood Leukemia Study Group

Analysis of a Global Registration Trial of the Efficacy and Safety of CTL019 in Pediatric and Young Adults with Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL)

Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome

Reduced Production of Mature Neutrophils From Induced Pluripotent Stem Cells Derived From a Severe Congenital Neutropenia Patient with HAX1 Gene Deficiency

Establishment of a Novel CNS Infiltrated Xenograft Model through Engraftment of Patient-Derived Acute Lymphoblastic Leukemic Cells Into NOD/SCID/γc Null Mouse

Enriched MicroRNA-126 Bioactivity Marks the Primitive Compartment In AML and Regulates LSC Numbers

Identification and Function of Hematopoietic Stem and Progenitor Cell Specific Micrornas.

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American Society of Hematology

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American Society of Hematology

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