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Freda H Passam
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Journal Articles

Platelet Endoplasmic Reticulum Stress Promotes Thrombosis in an in Vitro Laser-Induced Endothelial Injury Model

Alexander Dupuy, Paul Coleman, Jennifer Gamble, Lining Ju, Freda H Passam
Journal: Blood
Blood (2024) 144 (Supplement 1): 1233.
https://doi.org/10.1182/blood-2024-212327
Published: 2024
Journal Articles

Clinical Response to Azacitidine in Myelodysplastic Neoplasms Is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor Cells In Vivo

Julie A.I. Thoms, Feng Yan, Henry R. Hampton, Sarah Davidson, Swapna Joshi, Jesslyn Saw, Chowdhury H. Sarowar, Xin Ying Lim, Andrea C Nunez, Purvi M. Kakadia, Golam Sarower Bhuyan, Xiaoheng Zou, Mary Nguyen, Elaheh S Ghodousi, Forrest C Koch, Fatemeh Vafaee, I. Richard Thompson, Mohammad M. Karimi, Russell Pickford, Mark J Raftery, Sally Hough, Griselda Buckland, Michelle Bailey, Yuvaraj Ghodke, Noorul Absar, Lachlin Vaughan, Leonardo Pasalic, Chun Yew Fong, Melita Kenealy, Devendra Hiwase, Rohanna Stoddart, Soma Mohammed, Linda Lee, Freda H Passam, Stephen Robert Larsen, Kevin J Spring, Kristen K Skarratt, Patricia Rebeiro, Peter Presgrave, William S Stevenson, Silvia Ling, Campbell Tiley, Stephen Fuller, Fernando Roncolato, Anoop K Enjeti, Dirk Hoenemann, Charlotte Lemech, Christopher J Jolly, Stefan K. Bohlander, David J. Curtis, Jason Wong, Ashwin Unnikrishnan, Mark S. Hertzberg, Jake Olivier, Mark N Polizzotto, John E Pimanda
Journal: Blood
Blood (2024) 144 (Supplement 1): 3223.
https://doi.org/10.1182/blood-2024-201216
Published: 2024
Journal Articles

GPIbα–filamin A interaction regulates megakaryocyte localization and budding during platelet biogenesis

Marc L. Ellis, Antoine Terreaux, Imala Alwis, Rhyll Smythe, Jose Perdomo, Anita Eckly, Susan L. Cranmer, Freda H. Passam, Jessica Maclean, Simone M. Schoenwaelder, Zaverio M. Ruggeri, Francois Lanza, Samir Taoudi, Yuping Yuan, Shaun P. Jackson
Journal: Blood
Blood (2024) 143 (4): 342–356.
https://doi.org/10.1182/blood.2023021292
Published: 2024
Includes: Supplemental data
Journal Articles

SEC61B Regulates Calcium Flux and Platelet Hyperactivity in Diabetes Mellitus

Yvonne X Kong, Rajan Rehan, Cesar L Moreno, Huiwen Zhao, David James, Michelle Cielesh, Grant Morahan, Sian Cartland, Mary Kavurma, Greg Neely, Matthew T. Rondina, James Weaver, Mark Larance, Freda H Passam
Journal: Blood
Blood (2023) 142 (Supplement 1): 680.
https://doi.org/10.1182/blood-2023-180297
Published: 2023
Journal Articles

In Vivo Drug Incorporation and Intracellular Dynamics of Injectable Versus Oral Azacytidine: A Phase II Open Label Multicentre Trial

John E. Pimanda, Julie A.I. Thoms, Henry R. Hampton, Sarah Davidson, Swapna Joshi, Chowdhury H. Sarowar, Xin Ying Lim, Andrea C. Nunez, Purvi M. Kakadia, Russell Pickford, Mark Raftery, Sally Hough, Griselda Buckland, Michelle Bailey, Yuvaraj Ghodke, Noorul Absar, Lachlin Vaughan, Leonardo Pasalic, Chun Yew Fong, Melita Kenealy, Devendra Hiwase, Rohanna Stoddart, Soma Mohammed, Linda Lee, Freda H. Passam, Kevin Spring, Kristy K. Skarratt, Patricia Rebeiro, Stephen R Larsen, Peter Presgrave, William S Stevenson, Silvia Ling, Campbell Tiley, Stephen Fuller, Fernando Roncolato, Anoop Kumar Enjeti, Dirk Hoenemann, Charlotte Lemech, Stefan K. Bohlander, Jake Olivier, Mark Hertzberg, Ashwin Unnikrishnan, Mark N. Polizzotto
Journal: Blood
Blood (2022) 140 (Supplement 1): 6927–6929.
https://doi.org/10.1182/blood-2022-157634
Published: 2022
Journal Articles

Endothelial Cell Activation Enhances Thromboinflammation in Vitt

Alexander Dupuy, Xiaoming Liu, Jessica Tieng, Bede Johnston, Arian Nasser, Paul Coleman, Yingqi Zhang, Lining Arnold Ju, Huyen Tran, Vivien M Chen, Elizabeth E. Gardiner, Freda H. Passam
Journal: Blood
Blood (2022) 140 (Supplement 1): 1656–1657.
https://doi.org/10.1182/blood-2022-168441
Published: 2022
Journal Articles

Protein Disulphide Isomerase 6 (PDIA6) Attenuates Platelet Endoplasmic Reticulum Stress and Secretion in a Mouse Model

Freda H. Passam, Angelina Lay, Alexander Dupuy, Jessica Tieng, Lejla Hagimola, Jessica Maclean, Marc Ellis, Philip Hogg
Journal: Blood
Blood (2021) 138 (Supplement 1): 3138.
https://doi.org/10.1182/blood-2021-152307
Published: 2021
Journal Articles

Flow Cytometric Detection of Procoagulant Properties of Plasma from Patients with Clinically Confirmed Vaccine-Induced Immune Thrombotic Thrombocytopenia

Christine Shu Mei Lee, Agnibesh Dey, Heather Campbell, Emmanuel J Favaloro, Lisa Clarke, Freda H. Passam, Timothy Brighton, Vivien Chen
Journal: Blood
Blood (2021) 138 (Supplement 1): 3211.
https://doi.org/10.1182/blood-2021-148261
Published: 2021
Journal Articles

Determining the Rate of Anti-PF4 Antibody Positive Results in Patients Presenting with Venous Thrombosis but a Normal Platelet Count Following ChAdOx1 Ncov-19 Astrazeneca Vaccination: An Australian Combined State Testing Centre Experience

Emma J Leitinger, Joanne Clifford, Michael Parker, Amanda Iacobelli, Pauline Sung, Vivien Chen, Timothy A. Brighton, Christine Shu Mei Lee, Lisa Clarke, Erica Malan, Geoffrey Kershaw, Noor Shadood, Freda H. Passam, Emmanuel J Favaloro, Huyen A Tran, Sanjeev D Chunilal
Journal: Blood
Blood (2021) 138 (Supplement 1): 3216.
https://doi.org/10.1182/blood-2021-151822
Published: 2021
Journal Articles

In Vivo Assessment of Intracellular Dynamics Comparing Injection Versus Oral Azacitidine in a Phase IIb Investigator Initiated Clinical Trial

Ashwin Unnikrishnan, PhD, Xin Ying Lim, PhD, Swapna Joshi, Andrea C. Nunez, PhD, Lachlin Vaughan, MBBS, BSc, FRACP, FRCPA, Russell Pickford, PhD, Sally Hough, Sarah Davidson, Chun Fong, Melita Kenealy, MD, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD, Leonardo Pasalic, MBBS, PhD, Soma Mohammed, Linda Lee, PhD, Freda H. Passam, MD PhD, Kevin Spring, PhD, Patricia Rebeiro, MD, Silvia Ling, MBBS, PhD, Stephen Fuller, MBBS, PhD, Peter Presgrave, MBBS, Fernando Roncolato, BMed, FRACP, FRCPA, Stephen Larsen, MBBS, PhD FRACP, FRCPA, Anoop K Enjeti, MBBS,FRCPA, FRACP,PhDMD,MRCP, William S. Stevenson, MBBS, PhD, Campbell Tiley, MBBS, FRACP, Peter J Campbell, Charlotte Lemech, MD FRACP, Jake Olivier, PhD, Mark Hertzberg, MD MBBS, PhD, Mark N. Polizzotto, MBBS, FRACP, FRCPA, John Pimanda, MBBS, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4247.
https://doi.org/10.1182/blood-2019-123921
Published: 2019
Journal Articles

Neutrophil Activation and Netosis Are the Key Drivers of Thrombosis in Heparin-Induced Thrombocytopenia

Jose Perdomo, PhD, Halina HL Leung, PhD, Zohra Ahmadi, Yan Feng, PhD, Freda H. Passam, MDPhD, Beng H Chong, MBBS, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 378.
https://doi.org/10.1182/blood-2018-99-116421
Published: 2018
Journal Articles

Both platelet- and endothelial cell–derived ERp5 support thrombus formation in a laser-induced mouse model of thrombosis

Freda H. Passam, Lin Lin, Srila Gopal, Jack D. Stopa, Lola Bellido-Martin, Mingdong Huang, Barbara C. Furie, Bruce Furie
Journal: Blood
Blood (2015) 125 (14): 2276–2285.
https://doi.org/10.1182/blood-2013-12-547208
Published: 2015
Includes: Supplemental data
Journal Articles

Protein Disulfide Isomerase Inhibitors: A New Class of Antithrombotic Agents

Reema Jasuja, Ph.D., Freda H. Passam, MD, PhD, Daniel R Kennedy, Ph.D., Sarah H Kim, Lotte van Hessem, Lin Lin, PhD, Sucharit S Joshi, MD, James R. Dilks, Bruce Furie, MD, Barbara C. Furie, PhD, Robert C. Flaumenhaft, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 369.
https://doi.org/10.1182/blood.V118.21.369.369
Published: 2011
Journal Articles

Role of Thiol Isomerase ERp5 in Thrombus Formation

Freda H. Passam, MD, PhD, Lin Lin, PhD, Mingdong Huang, PhD, Jonathan M. Gibbins, BSc, PhD, Bruce Furie, MD, Barbara C. Furie, PhD
Journal: Blood
Blood (2011) 118 (21): 370.
https://doi.org/10.1182/blood.V118.21.370.370
Published: 2011
Journal Articles

Naturally occurring free thiols within β2-glycoprotein I in vivo: nitrosylation, redox modification by endothelial cells, and regulation of oxidative stress–induced cell injury

Yiannis Ioannou, Jing-Yun Zhang, Freda H. Passam, Soheila Rahgozar, Jian Cheng Qi, Bill Giannakopoulos, Miao Qi, Pei Yu, Demin M. Yu, Philip J. Hogg, Steven A. Krilis
Journal: Blood
Blood (2010) 116 (11): 1961–1970.
https://doi.org/10.1182/blood-2009-04-215335
Published: 2010
Includes: Supplemental data
Journal Articles

Beta 2 glycoprotein I is a substrate of thiol oxidoreductases

Freda H. Passam, Soheila Rahgozar, Miao Qi, Mark J. Raftery, Jason W. H. Wong, Kumiko Tanaka, Yiannis Ioannou, Jing Yun Zhang, Rosalie Gemmell, Jian Chen Qi, Bill Giannakopoulos, Will E. Hughes, Philip J. Hogg, Steven A. Krilis
Journal: Blood
Blood (2010) 116 (11): 1995–1997.
https://doi.org/10.1182/blood-2010-02-271494
Published: 2010