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Rebecca Hannah
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Journal Articles

Delayed Trp53 Activation Protects Dnmt3a -Mutant Haematopoietic Stem Cells from Inflammatory Attrition

Ludovica Marando, George Giotopoulos, Pedro Madrigal, Dhoyazan M A Azazi, Ryan Asby, Maria Erendira Calleja-Cervantes, David Lara-Astiaso, Nicola K. Wilson, Rebecca Hannah, Jaana Bagri, Elsa Barnard, Sarah J Horton, Berthold Gottgens, Elli Papaemmanuil, Shuchi Agrawal Singh, Malgorzata Gozdecka, George S Vassiliou, Brian J P Huntly
Journal: Blood
Blood (2024) 144 (Supplement 1): 190.
https://doi.org/10.1182/blood-2024-201612
Published: 2024
Journal Articles

Multimodal Single Cell Analysis Reveals Hematopoietic Changes across the Human Lifespan

Tomoya Isobe, Mariana Quiroga Londoño, Nicole Mende, Emily Stephenson, Deena Iskander, Simone Webb, Issac Goh, Vijay Shanmugiah, Rebecca Hannah, Anindita Roy, Irene Roberts, Elisa Laurenti, Muzlifah Haniffa, Nicola K. Wilson, Berthold Gottgens
Journal: Blood
Blood (2024) 144 (Supplement 1): 2659.
https://doi.org/10.1182/blood-2024-204131
Published: 2024
Journal Articles

Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance

Akihiko Numata, Hui Si Kwok, Qi-Ling Zhou, Jia Li, Roberto Tirado-Magallanes, Vladimir Espinosa Angarica, Rebecca Hannah, Jihye Park, Chelsia Qiuxia Wang, Vaidehi Krishnan, Deepa Rajagopalan, Yanzhou Zhang, Siqin Zhou, Robert S. Welner, Motomi Osato, Sudhakar Jha, Stefan K. Bohlander, Berthold Göttgens, Henry Yang, Touati Benoukraf, John W. Lough, Deepak Bararia, Daniel G. Tenen
Journal: Blood
Blood (2020) 136 (15): 1735–1747.
https://doi.org/10.1182/blood.2019001279
Published: 2020
Includes: Supplemental data
Journal Articles

Single Cell RNA-Seq Characterises Pre-Leukemic Transformation Driven By CEBPA N321D in the Hoxb8-FL Cell Line

Moosa Qureshi, MBBS, MRCP, Fernando Calero-Nieto, Iwo Kucinski, Sarah Kinston, George Giotopoulos, Dean Pask, Rebecca Hannah, Evangelia Diamanti, Xiaonan Wang, Reiner Schulte, Chiara Cossetti, Anthony R Green, Brian J.P Huntly, Berthold Gottgens
Journal: Blood
Blood (2018) 132 (Supplement 1): 3887.
https://doi.org/10.1182/blood-2018-99-110626
Published: 2018
Journal Articles

The Lysine Acetyltransferase Tip60 Is Required for Hematopoietic Stem Cell Maintenance

Akihiko Numata, MD, Hui Si Kwok, PhD, Qi-Ling Zhou, Jia Li, PhD, Rebecca Hannah, Jihye Park, PhD, Vladimir Espinosa Angarcia, PhD, Berthold Gottgens, Henry Yang, PhD, John Lough, PhD, Deepak Bararia, PhD, Daniel G. Tenen, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2554.
https://doi.org/10.1182/blood-2018-99-118316
Published: 2018
Journal Articles

A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice

e-blood
Joakim S. Dahlin, Fiona K. Hamey, Blanca Pijuan-Sala, Mairi Shepherd, Winnie W. Y. Lau, Sonia Nestorowa, Caleb Weinreb, Samuel Wolock, Rebecca Hannah, Evangelia Diamanti, David G. Kent, Berthold Göttgens, Nicola K. Wilson
Journal: Blood
Blood (2018) 131 (21): e1–e11.
https://doi.org/10.1182/blood-2017-12-821413
Published: 2018
Includes: Supplemental data
Journal Articles

Cellular Model of CEBPA N321D Captures Gene Expression Profile in the Transition to Pre-Leukaemic Status

Moosa Qureshi, Wajid Jawaid, Fernando J Calero-Nieto, PhD, Rebecca Hannah, Sarah J Kinston, Evangelia Diamanti, Winnie W Lau, PhD, Isabel Jimenez-Madrid, Chiara Cossetti, PhD, Berthold Gottgens, DPhil
Journal: Blood
Blood (2016) 128 (22): 3922.
https://doi.org/10.1182/blood.V128.22.3922.3922
Published: 2016
Journal Articles

Integrated genome-scale analysis of the transcriptional regulatory landscape in a blood stem/progenitor cell model

e-blood
Nicola K. Wilson, Stefan Schoenfelder, Rebecca Hannah, Manuel Sánchez Castillo, Judith Schütte, Vasileios Ladopoulos, Joanna Mitchelmore, Debbie K. Goode, Fernando J. Calero-Nieto, Victoria Moignard, Adam C. Wilkinson, Isabel Jimenez-Madrid, Sarah Kinston, Mikhail Spivakov, Peter Fraser, Berthold Göttgens
Journal: Blood
Blood (2016) 127 (13): e12–e23.
https://doi.org/10.1182/blood-2015-10-677393
Published: 2016
Includes: Supplemental data
Journal Articles

The JAK-STAT signaling pathway is differentially activated in CALR -positive compared with JAK2V617F -positive ET patients

Winnie W. Y. Lau, Rebecca Hannah, Anthony R. Green, Bertie Göttgens
Journal: Blood
Blood (2015) 125 (10): 1679–1681.
https://doi.org/10.1182/blood-2014-12-618074
Published: 2015
Journal Articles

Genome-Scale Analysis of the Pu.1 Driven Transcriptional Programme That Overcomes the Differentiation Block in a Novel Pu.1-Inducible AML Cell Line

Jonathan I Sive, MBChB, Fernando J Calero-Nieto, PhD, Rebecca Hannah, MSc, Berthold Göttgens, PhD
Journal: Blood
Blood (2014) 124 (21): 869.
https://doi.org/10.1182/blood.V124.21.869.869
Published: 2014
Journal Articles

Large Conserved Domains Of Low DNA Methylation Maintained By 5-Hydroxymethycytosine and Dnmt3a

Mira Jeong, Ph.D., Deqiang Sun, Min Luo, Ph.D., Yun Huang, PhD, Myunggon Ko, PhD, Lucas Chavez, Grant A Challen, PhD, Benjamin Rodriguez, Xiaotian Zhang, B.S, Liubin Yang, Hui Wang, Ph.D., Rui Chen, Ph.D., Rebecca Hannah, Ph.D., Sang-Bae Kim, Ju-Seog Lee, Berthold Gottgens, Ph.D., Preethi Gunaratne, Lucy A Godley, Gretchen Darlington, Ph.D., Anjana Rao, PhD, Wei Li, Ph.D., Margaret A. Goodell, PhD
Journal: Blood
Blood (2013) 122 (21): 2406.
https://doi.org/10.1182/blood.V122.21.2406.2406
Published: 2013
Journal Articles

HSC Aging Epigenome: Widespread Alterations in DNA Methylation and Transcription.

Mira Jeong, Ph.D., Min Luo, Ph.D., Deqiang Sun, Ph.D., Gretchen Darlington, Ph.D., Rebecca Hannah, Ph.D., Berthold Gottgens, Ph.D., Hui Wang, Ph.D., Rui Chen, Ph.D., Wei Li, Ph.D., Margaret A. Goodell, PhD
Journal: Blood
Blood (2012) 120 (21): 2329.
https://doi.org/10.1182/blood.V120.21.2329.2329
Published: 2012
Journal Articles

The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice

Cyrus Khandanpour, Joseph Krongold, Judith Schütte, Frederique Bouwman, Lothar Vassen, Marie-Claude Gaudreau, Riyan Chen, Fernando J. Calero-Nieto, Evangelia Diamanti, Rebecca Hannah, Sara E. Meyer, H. Leighton Grimes, Bert A. van der Reijden, Joop H. Jansen, Chandrashekhar V. Patel, Justine K. Peeters, Bob Löwenberg, Ulrich Dührsen, Bertie Göttgens, Tarik Möröy
Journal: Blood
Blood (2012) 120 (19): 4006–4017.
https://doi.org/10.1182/blood-2011-02-334722
Published: 2012
Includes: Supplemental data
Journal Articles

The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis

Graeme M. Birdsey, Nicola H. Dryden, Aarti V. Shah, Rebecca Hannah, Matthew D. Hall, Dorian O. Haskard, Maddy Parsons, Justin C. Mason, Marketa Zvelebil, Berthold Gottgens, Anne J. Ridley, Anna M. Randi
Journal: Blood
Blood (2012) 119 (3): 894–903.
https://doi.org/10.1182/blood-2011-04-350025
Published: 2012
Includes: Multimedia, Supplemental data