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Journal Articles

From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formation

Tarik Möröy, Lothar Vassen, Brian Wilkes, Cyrus Khandanpour

Blood (2015) 126 (24): 2561–2569.

https://doi.org/10.1182/blood-2015-06-655043

Published: 2015

Journal Articles

The Zinc Finger Transcription Factor ( Growth Factor Independence 1b ) Gfi1b Regulates Megakaryocyte Proliferation and Their Ability To Produce and Release Platelets

Hugues Beauchemin, PhD, Lothar Vassen, PhD, Tarik Moroy, PhD

Blood (2013) 122 (21): 1173.

https://doi.org/10.1182/blood.V122.21.1173.1173

Published: 2013

Journal Articles

The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice

Blood (2012) 120 (19): 4006–4017.

https://doi.org/10.1182/blood-2011-02-334722

Published: 2012

Includes: Supplemental data

Journal Articles

Growth Factor Independent-1 (Gfi1) As a New Target for Human Leukemia Therapy

Cyrus Khandanpour, M.D., James D. Phelan, B.S., Riyan Chen, PhD., Shane Horman, PhD, Lothar Vassen, PhD, Marie-Claude Gaudreau, M.Sc., Joseph Krongold, BSc,, Jinfang Zhu, Ph.D., William E Paul, M.D., Judith Schütte, Berthold Goettgens, PhD., Ulrich Duehrsen, MD, H. Leighton Grimes, PhD, Tarik Moroy, Ph.D.

Blood (2011) 118 (21): 560.

https://doi.org/10.1182/blood.V118.21.560.560

Published: 2011

Journal Articles

Growth Factor Independence 1b (Gfi1b) Is An Essential Regulator of Late Stage Megakaryocyte Maturation and Platelet Production

Lothar Vassen, PhD, Tarik Moroy, Ph.D.

Blood (2011) 118 (21): 2358.

https://doi.org/10.1182/blood.V118.21.2358.2358

Published: 2011

Journal Articles

Growth Factor Independence 1b (Gfi1b) Is Required for the Regulation of Fetal Globin Genes in Both Fetal and Adult Erythroid Cells

Lothar Vassen, PhD, Wafaa Lemsaddek, Marie Trudel, DSc, Tarik Moroy, Ph.D.

Blood (2011) 118 (21): 350.

https://doi.org/10.1182/blood.V118.21.350.350

Published: 2011

Journal Articles

Growth Factor Independence 1 (Gfi1) Regulates Cell-Fate Decision of the Bipotential Granulocytic-Monocytic Precursors Defined by Expression of CD48 As a New Marker,

Lothar Vassen, PhD, Ulrich Duehrsen, MD, Christian Kosan, Ph.D., Hui Zeng, Tarik Moroy, Ph.D.

Blood (2011) 118 (21): 3217.

https://doi.org/10.1182/blood.V118.21.3217.3217

Published: 2011

Journal Articles

The Growth Factor Independence 1 variant form GFI136N Predisposes to Acute Myeloid Leukemia by Inducing Epigenetic Changes in Oncogenes Such As Hoxa9

Cyrus Khandanpour, MD, Joseph Krongold, BSc,, Judith Schütte, Frederique Bouwman, Lothar Vassen, PhD, Marie-Claude Gaudreau, M.Sc., Riyan Chen, PhD., Sara E. Meyer, PhD, H. Leighton Grimes, PhD, Bert A. Van der Reijden, PhD, Joop H. Jansen, PhD, Bob Lowenberg, MD, PhD, Justine K Peeters, Patel Chandrashekhar, Ulrich Duehrsen, MD, Berthold Goettgens, PhD., Tarik Moroy, Ph.D.

Blood (2011) 118 (21): 223.

https://doi.org/10.1182/blood.V118.21.223.223

Published: 2011

Journal Articles

IL-7R–dependent survival and differentiation of early T-lineage progenitors is regulated by the BTB/POZ domain transcription factor Miz-1

Ingrid Saba, Christian Kosan, Lothar Vassen, Tarik Möröy

Blood (2011) 117 (12): 3370–3381.

https://doi.org/10.1182/blood-2010-09-310680

Published: 2011

Includes: Supplemental data

Journal Articles

Evidence that Growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells

Cyrus Khandanpour, Ehssan Sharif-Askari, Lothar Vassen, Marie-Claude Gaudreau, Jinfang Zhu, William E. Paul, Taro Okayama, Christian Kosan, Tarik Möröy

Blood (2010) 116 (24): 5149–5161.

https://doi.org/10.1182/blood-2010-04-280305

Published: 2010

Journal Articles

A Human Variant of Growth Factor Independence 1 (GFI136N) Predisposes to Myeloid Leukemia In Mice

Cyrus Khandanpour, MD, Lothar Vassen, PhD, Marie-Claude Gaudreau, MSc, Joseph Krongold, Bert van der Reijden, Ph.D., Joop Jansen, MD, Ulrich Duehrsen, MD, Tarik Moroy, Ph.D.

Blood (2010) 116 (21): 997.

https://doi.org/10.1182/blood.V116.21.997.997

Published: 2010

Journal Articles

Growth Factor Independence 1 b (Gfi1b) as a New Regulator of Hematopoietic Stem Cell Fate

Cyrus Khandanpour, MD, Lothar Vassen, PhD, Marie-Claude Gaudreau, MSc, Christian Kosan, Ph.D., Tarik Moroy, Ph.D.

Blood (2010) 116 (21): 837.

https://doi.org/10.1182/blood.V116.21.837.837

Published: 2010

Journal Articles

The Zinc Finger Protein Gfi1 Controls TLR4-Mediated Inflammatory Response by Directly Antagonizing NF-κB Transcription Factor

Ehssan Sharif-Askari, PhD, Hui Zeng, MD, PhD, Lothar Vassen, PhD, Christian Kosan, PhD, Cyrus Khandanpour, MD, Florian Heyd, PhD, Tarik Moroy, PhD

Blood (2008) 112 (11): 469.

https://doi.org/10.1182/blood.V112.11.469.469

Published: 2008

Journal Articles

Growth Factor Independent 1b (Gfi1b) Is Highly Expressed in Human CML and Accelerates p210 BCR-ABL Induced Leukemia in Mice.

Lothar Vassen, PhD, Daniel G. Tenen, Ph.D., Bert A. van der Reijden, Ph.D., Ulrich Duehrsen, Ph.D., Tarik Moroy, Ph.D., Stefan Mahlmann, Ph.D., Peter Ebeling, Ph.D., Joop H. Jansen, Ph.D.

Blood (2007) 110 (11): 1023.

https://doi.org/10.1182/blood.V110.11.1023.1023

Published: 2007

Journal Articles

Gfi1b:green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1

Lothar Vassen, Taro Okayama, Tarik Möröy

Blood (2006) 109 (6): 2356–2364.

https://doi.org/10.1182/blood-2006-06-030031

Published: 2006

Includes: Supplemental data

NARROW

From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formation

The Zinc Finger Transcription Factor ( Growth Factor Independence 1b ) Gfi1b Regulates Megakaryocyte Proliferation and Their Ability To Produce and Release Platelets

The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice

Growth Factor Independent-1 (Gfi1) As a New Target for Human Leukemia Therapy

Growth Factor Independence 1b (Gfi1b) Is An Essential Regulator of Late Stage Megakaryocyte Maturation and Platelet Production

Growth Factor Independence 1b (Gfi1b) Is Required for the Regulation of Fetal Globin Genes in Both Fetal and Adult Erythroid Cells

Growth Factor Independence 1 (Gfi1) Regulates Cell-Fate Decision of the Bipotential Granulocytic-Monocytic Precursors Defined by Expression of CD48 As a New Marker,

The Growth Factor Independence 1 variant form GFI136N Predisposes to Acute Myeloid Leukemia by Inducing Epigenetic Changes in Oncogenes Such As Hoxa9

IL-7R–dependent survival and differentiation of early T-lineage progenitors is regulated by the BTB/POZ domain transcription factor Miz-1

Evidence that Growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells

A Human Variant of Growth Factor Independence 1 (GFI136N) Predisposes to Myeloid Leukemia In Mice

Growth Factor Independence 1 b (Gfi1b) as a New Regulator of Hematopoietic Stem Cell Fate

The Zinc Finger Protein Gfi1 Controls TLR4-Mediated Inflammatory Response by Directly Antagonizing NF-κB Transcription Factor

Growth Factor Independent 1b (Gfi1b) Is Highly Expressed in Human CML and Accelerates p210 BCR-ABL Induced Leukemia in Mice.

Gfi1b:green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1

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American Society of Hematology

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American Society of Hematology

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