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Journal Articles

Highly-Sensitive DNA Hydroxymethylation Analysis in Myelodysplastic Syndromes (MDS)

Jia Li, PhD, Yue Wei, PhD, Minjung Lee, Hui Yang, MD PhD, Caleb Class, PhD, Stefan Siwko, Yubin Zhou, PhD, Deqiang Sun, PhD, Guillermo Garcia-Manero, MD, Yun Huang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17.
https://doi.org/10.1182/blood-2020-137733
Published: 2020
Journal Articles

Tet2 Inactivation Enhances the Anti-Tumor Activity of Tumor-Infiltrating Lymphocytes (TILs) to Curtail Melanoma Growth

Minjung Lee, PhD, Jianfang Li, PhD, Shaohai Fang, MS, Joanna Zhang, Anh Tran Tram Vo, Wei Han, MS, Hongxiang Zeng, PhD, Sevinj Isgandarova, Margarita Martinez Moczygemba, PhD, Yubin Zhou, PhD, Jia Li, PhD, Deqiang Sun, PhD, Yun Huang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 27.
https://doi.org/10.1182/blood-2020-137242
Published: 2020
Journal Articles

Comprehensive DNA 5-Hydroxymethylation Landscapes in Myelodysplastic Syndromes (MDS)

Jia Li, PhD, Yue Wei, PhD, Minjung Lee, MS, Caleb Class, PhD, Hui Yang, PhDMD, Deqiang Sun, PhD, Guillermo Garcia-Manero, MD, Yun Huang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2996.
https://doi.org/10.1182/blood-2019-128599
Published: 2019
Journal Articles

A Combination Strategy Targeting Enhancer Plasticity Exerts Synergistic Lethality Against Beti-Resistant Leukemia Cells

Lei Guo, PhD, Jia Li, PhD, Hongxiang Zeng, PhD, Anna Guzman, Tingting Li, MD, Minjung Lee, MS, Yubin Zhou, PhD, Clifford Stephan, Peter J.A Davies, Margaret Goodell, PhD, Deqiang Sun, PhD, Mark A. Dawson, PhD MBBS, Yun Huang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5053.
https://doi.org/10.1182/blood-2019-130586
Published: 2019
Journal Articles

Antibiotics Treatment Ameliorates TET2 Loss of Function Associated Hematological Malignancies

Hongxiang Zeng, PhD, Hailan He, MS, Jia Li, PhD, Wei Han, MS, Anna Guzman, Deqiang Sun, PhD, Katherine Y. King, MD PhD, Margaret A. Goodell, PhD, Yun Huang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2610.
https://doi.org/10.1182/blood-2018-99-116424
Published: 2018
Journal Articles

Tet2 Deficiency in Macrophages Undermines Heart Repair after Infarction

Shaohai Fang, MS, Yang Xiao, PhD, Jia Li, PhD, Tingting Li, MD, Hongxiang Zeng, PhD, Wei Han, MS, Yubin Zhou, PhD, Deqiang Sun, PhD, James M. Martin, MD, Yun Huang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2394.
https://doi.org/10.1182/blood-2018-99-115358
Published: 2018
Journal Articles

Synthetic Lethality of Combinatory Inhibition of BET and CDK7 in BET(i) Resistant Leukemia Cells

Lei Guo, PhD, Jia Li, PhD, Shaohai Fang, MS, Minjung Lee, MS, Hongxiang Zeng, PhD, Tingting Li, MD, Wei Han, MS, Deqiang Sun, PhD, Yun Huang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1354.
https://doi.org/10.1182/blood-2018-99-116634
Published: 2018
Journal Articles

Disruption of TET2 Dioxygenase Enhances Antitumor Efficiency in CD8+ Tumor Infiltrating Lymphocytes

Minjung Lee, MS, Hongxiang Zeng, PhD, Jia Li, PhD, Wei Han, MS, Deqiang Sun, PhD, Yun Huang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 860.
https://doi.org/10.1182/blood-2018-99-115405
Published: 2018
Journal Articles

Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation

Katie A Matatall, PhD, Mira Jeong, PhD, Fengju Chen, Siyi Chen, Deqiang Sun, Qianxiang Mo, Marek Kimmel, PhD DSc, Katherine Y. King, MD PhD
Journal: Blood
Blood (2016) 128 (22): 732.
https://doi.org/10.1182/blood.V128.22.732.732
Published: 2016
Journal Articles

Large Conserved Domains Of Low DNA Methylation Maintained By 5-Hydroxymethycytosine and Dnmt3a

Mira Jeong, Ph.D., Deqiang Sun, Min Luo, Ph.D., Yun Huang, PhD, Myunggon Ko, PhD, Lucas Chavez, Grant A Challen, PhD, Benjamin Rodriguez, Xiaotian Zhang, B.S, Liubin Yang, Hui Wang, Ph.D., Rui Chen, Ph.D., Rebecca Hannah, Ph.D., Sang-Bae Kim, Ju-Seog Lee, Berthold Gottgens, Ph.D., Preethi Gunaratne, Lucy A Godley, Gretchen Darlington, Ph.D., Anjana Rao, PhD, Wei Li, Ph.D., Margaret A. Goodell, PhD
Journal: Blood
Blood (2013) 122 (21): 2406.
https://doi.org/10.1182/blood.V122.21.2406.2406
Published: 2013
Journal Articles

Dnmt3b Has Few Specific Functions In Adult Hematopoietic Stem Cells But Shows Abnormal Activity In The Absence Of Dnmt3a

Grant A Challen, PhD, Allison Mayle, Deqiang Sun, Mira Jeong, Ph.D., Min Luo, Ph.D., Wei Li, Ph.D., Margaret A. Goodell, PhD
Journal: Blood
Blood (2013) 122 (21): 734.
https://doi.org/10.1182/blood.V122.21.734.734
Published: 2013
Journal Articles

Long Non-Coding RNAs Control Hematopoietic Stem Cells (HSC) Function

Min Luo, Ph.D., Mira Jeong, Ph.D., Deqiang Sun, Ph.D., Hyun-Jung Park, PhD, Liubin Yang, Hui Wang, Ph.D., Rui Chen, Ph.D., Gretchen Darlington, Ph.D., Wei Li, Ph.D., Margaret A. Goodell, PhD
Journal: Blood
Blood (2013) 122 (21): 48.
https://doi.org/10.1182/blood.V122.21.48.48
Published: 2013
Journal Articles

Histone Alterations Are Associated with Hematopoietic Stem Cell (HSC) Differentiation and Aging

Min Luo, Ph.D., Mira Jeong, Ph.D., Deqiang Sun, Ph.D., Hui Wang, Ph.D., Rui Chen, Ph.D., Wei Li, Ph.D., Gretchen Darlington, Ph.D., Margaret A. Goodell, PhD
Journal: Blood
Blood (2012) 120 (21): 1188.
https://doi.org/10.1182/blood.V120.21.1188.1188
Published: 2012
Journal Articles

Dnmt3b Is Dispensable for Hematopoietic Stem Cell Differentiation, but Acts Synergistically with Dnmt3a to Control the Balance Between Self-Renewal and Differentiation

Allison Mayle, Grant Anthony Challen, PhD, Deqiang Sun, Ph.D., Mira Jeong, Ph.D., Min Luo, Ph.D., Rui Chen, Ph.D., Hui Wang, Ph.D., Wei Li, Ph.D., Margaret A. Goodell, PhD
Journal: Blood
Blood (2012) 120 (21): 848.
https://doi.org/10.1182/blood.V120.21.848.848
Published: 2012
Journal Articles

HSC Aging Epigenome: Widespread Alterations in DNA Methylation and Transcription.

Mira Jeong, Ph.D., Min Luo, Ph.D., Deqiang Sun, Ph.D., Gretchen Darlington, Ph.D., Rebecca Hannah, Ph.D., Berthold Gottgens, Ph.D., Hui Wang, Ph.D., Rui Chen, Ph.D., Wei Li, Ph.D., Margaret A. Goodell, PhD
Journal: Blood
Blood (2012) 120 (21): 2329.
https://doi.org/10.1182/blood.V120.21.2329.2329
Published: 2012
Journal Articles

Dnmt3a Is Essential for Hematopoietic Stem Cell Differentiation

Grant A. Challen, PhD, Deqiang Sun, Ph.D., Mira Jeong, Ph.D., Min Luo, Ph.D., Jaroslav Jelinek, MD, PhD, Aparna Vasanthakumar, Ph.D., Alexander Meissner, Ph.D., Jean-Pierre Issa, MD, Lucy Godley, MD, PhD, Wei Li, Ph.D., Margaret A. Goodell, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 386.
https://doi.org/10.1182/blood.V118.21.386.386
Published: 2011
Journal Articles

Genome Wide DNA Methylation and Transcriptome Analysis in HSC Aging

Mira Jeong, Ph.D., Deqiang Sun, Min Luo, Ph.D., Aysegul Ergen, Hongcang Gu, Christoph Bock, Alexander Meissner, Gretchen Darlington, Wei Li, Ph.D., Margaret A. Goodell, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 2367.
https://doi.org/10.1182/blood.V118.21.2367.2367
Published: 2011