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Journal Articles

Acquired expression of Cbl Q367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia

Yuichiro Nakata, Takeshi Ueda, Akiko Nagamachi, Norimasa Yamasaki, Ken-ichiro Ikeda, Yasuyuki Sera, Keiyo Takubo, Akinori Kanai, Hideaki Oda, Masashi Sanada, Seishi Ogawa, Kohichiro Tsuji, Yasuhiro Ebihara, Linda Wolff, Zen-ichiro Honda, Toshio Suda, Toshiya Inaba, Hiroaki Honda

Blood (2017) 129 (15): 2148–2160.

https://doi.org/10.1182/blood-2016-06-724658

Published: 2017

Includes: Supplemental data

Journal Articles

A Comparison of Myelopoiesis from Induced Pluripotent Stem Cells with a Mutation in ELANE between Cyclic Neutropenia and Severe Congenital Neutropenia

Satoshi Saito, MD, Shiho Nishimura, MD, Miyuki Tsumura, PhD, Yoko Mizoguchi, MD PhD, Sonoko Sakata, MD, Aya Furue, MD, Mizuka Miki, MD, Hiroshi Kawaguchi, MD PhD, Takafumi Hiramoto, PhD, Yasuhiro Ebihara, MD PhD, Kohichiro Tsuji, MD, Tatsutoshi Nakahata, MD, PhD, Masao Kobayashi, MD PhD

Blood (2015) 126 (23): 2193.

https://doi.org/10.1182/blood.V126.23.2193.2193

Published: 2015

Journal Articles

Impaired Hematopoietic Differentiation of iPSCs Derived From Patients with FPD/AML

Masatoshi Sakurai, MD, Hiroyoshi Kunimoto, MD, Naohide Watanabe, MD, PhD, Yumi Fukuchi, PhD, Ken Sadahira, MD, Shinsuke Yuasa, MD, PhD, Keiichi Fukuda, MD, PhD, Satoshi Yamazaki, PhD, Hiromitsu Nakauchi, MD, PhD, Yasuhiro Ebihara, MD, PhD, Kohichiro Tsuji, MD, PhD, Etsuro Ito, Yuka Harada, MD, PhD, Hironori Harada, MD, PhD, Shinichiro Okamoto, MD, PhD, Hideaki Nakajima, MD, PhD

Blood (2012) 120 (21): 767.

https://doi.org/10.1182/blood.V120.21.767.767

Published: 2012

Journal Articles

Suppressed Neutrophil Development in Hematopoiesis of Induced Pluripotent Stem Cells Derived From a Severe Congenital Neutropenia Patient with ELA2 Mutation

Takafumi Hiramoto, Yasuhiro Ebihara, MD, PhD, Yoko Mizoguchi, MD, Kazuhiro Nakamura, MD, PhD, Shinji Mochizuki, MD, PhD, Shohei Yamamoto, MD, PhD, Emiko Matsuzaka, PhD, Sachiyo Hanada, Ryoko Ohnishi, Kenzaburo Tani, PhD, M.D., Koji Eto, M.D., Ph.D., Hiromitsu Nakauchi, MD, PhD, Masao Kobayashi, MD, PhD, Kohichiro Tsuji, MD, PhD

Blood (2011) 118 (21): 730.

https://doi.org/10.1182/blood.V118.21.730.730

Published: 2011

Journal Articles

Matched HLA Haplotype Contributes to Reduce Sever Acute GVHD with Conserving GVL Effect in HLA-Mismatched Cord Blood Transplantation,

Satoshi Takahashi, M.D., Ph.D., Jun Ooi, MD, Seiko Kato, M.D., Toshiro Kawakita, M.D., Arinobu Tojo, MD, PhD, Yasuhiro Ebihara, MD, PhD, Shinji Mochizuki, MD, PhD, Shohei Yamamoto, MD, PhD, Kohichiro Tsuji, MD, PhD, Takuhiro Yamaguchi, Ph.D., Satoko Morishima, MD., Ph.D., Yasuo Morishima, MD, PhD, Shigetaka Asano, MD

Blood (2011) 118 (21): 4140.

https://doi.org/10.1182/blood.V118.21.4140.4140

Published: 2011

Journal Articles

Low-Dose Cytosine Arabinoside Therapy for Neonates with Down Syndrome (DS) and Transient Leukemia (TL).

Hideki Muramatsu, MD, PhD, Yasuhide Hayashi, MD, PhD, Machiko Kawamura, MD, PhD, Seiji Kojima, MD, PhD, Miharu Yabe, Keiichi Isoyama, Tomohiko Taki, MD, PhD, Kohichiro Tsuji, MD, PhD, Masahiro Tsuchida, MD, PhD, Atsushi Manabe, Etsuro Ito, MD, PhD, Shotaro Iwamoto, MD, PhD, Hiromi Kato, Aiko Sumie, Takashi Taga, MD, PhD, Keiko Nomura, Daisuke Hasegawa, MD, PhD, Ken-ichiro Watanabe, Akira Kikuchi

Blood (2010) 116 (21): 1074.

https://doi.org/10.1182/blood.V116.21.1074.1074

Published: 2010

Journal Articles

A Novel MBT-Containing Protein, Hemp, Plays Essential Roles In Skeletal Formation and Hematopoietic Stem Cell Function.

Phyo Wai Htun, Keiyo Takubo, Hideaki Oda, Feng Ma, Kenjiro Kosaki, Kateri A. Moore, Norimasa Yamasaki, Kohichiro Tsuji, Ihor R. Lemischka, Toshio Suda, Hiroaki Honda

Blood (2010) 116 (21): 1597.

https://doi.org/10.1182/blood.V116.21.1597.1597

Published: 2010

Journal Articles

Differentiation of Mature Eosinophils From Human Embryonic and Induced Pluripotent Stem Cells.

Wenyu Yang, Feng Ma, MD, PhD, Kenji Matsumoto, Natsumi Nishihama, Hiroshi Sagara, Yasuhiro Ebihara, MD, PhD, Yanzheng Gu, Hirohisa Saito, MD, PhD, Xiaofan Zhu, MD, PhD, Hiromitsu Nakauchi, MD, PhD, Kohichiro Tsuji, MD, PhD

Blood (2010) 116 (21): 1594.

https://doi.org/10.1182/blood.V116.21.1594.1594

Published: 2010

Journal Articles

Hematopoiesis of Human Induced Pluripotent Stem Cells Derived From Patients with Down Syndrome

Natsumi Nishihama, Yasuhiro Ebihara, MD, PhD, Feng Ma, MD, PhD, Wenyu Yang, MD, Daisuke Tomizawa, MD, Shinji Mochizuki, MD, PhD, Kiyoshi Yamaguchi, PhD, Masaharu Hiratsuka, PhD, Yoichi Furukawa, MD, PhD, Mitsuo Oshimura, MD, PhD, Hiromitsu Nakauchi, MD, PhD, Kohichiro Tsuji, MD, PhD

Blood (2010) 116 (21): 881.

https://doi.org/10.1182/blood.V116.21.881.881

Published: 2010

Journal Articles

Myelodysplastic Syndrome (MDS) and Myeloproliferative Disease (MPD) in Children: A Prospective Registration of 222 Cases

Shinsuke Hirabayashi, MD, Atsushi Manabe, MD, Shizuka Watanabe, Yuji Zaike, Masahiro Tsuchida, MD, Atsuko Masunaga, MD, Ayami Yoshimi, MD, Masafumi Ito, MD, Akira Kikuchi, MD, Kohichiro Tsuji, MD, Akira Ohara, MD, Seiji Kojima, MD, Tatsutoshi Nakahata, MD

Blood (2008) 112 (11): 2678.

https://doi.org/10.1182/blood.V112.11.2678.2678

Published: 2008

Journal Articles

Clonal Analysis of Progressive Maturation of Erythroid Cells from Human Embryonic Stem Cell-Derived Definitive Hematopoiesis.

Feng Ma, Yasuhiro Ebihara, Katsutsugu Umeda, Hiromi Sakai, Sachiyo Hanada, Hong Zhang, Eishun Tsuchida, Tatsutoshi Nakahata, Hiromitsu Nakauchi, Kohichiro Tsuji

Blood (2007) 110 (11): 2236.

https://doi.org/10.1182/blood.V110.11.2236.2236

Published: 2007

Journal Articles

A Novel Method for Efficient Production of Multipotential Hematopoietic Progenitors from Human Embryonic Stem Cells by Co-Culture with Murine Fetal Liver-Derived Stromal Cells.

Feng Ma, Dan Wang, Sachiyo Hanada, Hirohide Kawasaki, Yuji Zaike, Toshio Heike, Toshio Kitamura, Tatsutoshi Nakahata, Kohichiro Tsuji

Blood (2005) 106 (11): 4214.

https://doi.org/10.1182/blood.V106.11.4214.4214

Published: 2005

Journal Articles

RAS-blocking bisphosphonate zoledronic acid inhibits the abnormal proliferation and differentiation of juvenile myelomonocytic leukemia cells in vitro

Yoshitoshi Ohtsuka, Atsushi Manabe, Hirohide Kawasaki, Daisuke Hasegawa, Yuji Zaike, Sumiko Watanabe, Takakuni Tanizawa, Tatsutoshi Nakahata, Kohichiro Tsuji

Blood (2005) 106 (9): 3134–3141.

https://doi.org/10.1182/blood-2005-03-0972

Published: 2005

Journal Articles

Bisphosphonate Zoledronic Acid (ZOL) Inhibits the Abnormal Proliferation and Differentiation of Juvenile Myelomonocytic Leukemia (JMML) Cells.

Yoshitoshi Ohtsuka, MD, Atsushi Manabe, MD, Hirohide Kawasaki, MD, Sumiko Watanabe, MD, Yuji Zaike, Daisuke Hasegawa, MD, Toshiyasu Miyazaki, Takakuni Tanizawa, MD, Tatsutoshi Nakahata, MD, Kohichiro Tsuji, MD

Blood (2004) 104 (11): 4725.

https://doi.org/10.1182/blood.V104.11.4725.4725

Published: 2004

Journal Articles

Erythropoiesis from acetyl LDL incorporating endothelial cells at the preliver stage

Daisuke Sugiyama, Minetaro Ogawa, Imiko Hirose, Thierry Jaffredo, Ken-ichi Arai, Kohichiro Tsuji

Blood (2003) 101 (12): 4733–4738.

https://doi.org/10.1182/blood-2002-09-2799

Published: 2003

Journal Articles

Impaired neutrophil maturation in truncated murine G-CSF receptor–transgenic mice

Tetsuo Mitsui, Sumiko Watanabe, Yoshihiro Taniguchi, Sachiyo Hanada, Yasuhiro Ebihara, Takeshi Sato, Toshio Heike, Masao Mitsuyama, Tatsutoshi Nakahata, Kohichiro Tsuji

Blood (2003) 101 (8): 2990–2995.

https://doi.org/10.1182/blood.V101.8.2990

Published: 2003

Journal Articles

NOD/SCID/γ c null mouse: an excellent recipient mouse model for engraftment of human cells

Mamoru Ito, Hidefumi Hiramatsu, Kimio Kobayashi, Kazutomo Suzue, Mariko Kawahata, Kyoji Hioki, Yoshito Ueyama, Yoshio Koyanagi, Kazuo Sugamura, Kohichiro Tsuji, Toshio Heike, Tatsutoshi Nakahata

Blood (2002) 100 (9): 3175–3182.

https://doi.org/10.1182/blood-2001-12-0207

Published: 2002

Journal Articles

Human granulocyte-macrophage colony-stimulating factor (hGM-CSF) stimulates primitive and definitive erythropoiesis in mouse embryos expressing hGM-CSF receptors but not erythropoietin receptors

Hiroaki Hisakawa, Daisuke Sugiyama, Ichiko Nishijima, Ming-jiang Xu, Hong Wu, Kazuki Nakao, Sumiko Watanabe, Motoya Katsuki, Shigetaka Asano, Ken-ichi Arai, Tatsutoshi Nakahata, Kohichiro Tsuji

Blood (2001) 98 (13): 3618–3625.

https://doi.org/10.1182/blood.V98.13.3618

Published: 2001

Journal Articles

Generation of definitive hematopoietic stem cells from murine early yolk sac and paraaortic splanchnopleures by aorta-gonad-mesonephros region–derived stromal cells

Sahoko Matsuoka, Kohichiro Tsuji, Hiroaki Hisakawa, Ming-jiang Xu, Yasuhiro Ebihara, Takefumi Ishii, Daisuke Sugiyama, Atsushi Manabe, Ryuhei Tanaka, Yasuo Ikeda, Shigetaka Asano, Tatsutoshi Nakahata

Blood (2001) 98 (1): 6–12.

https://doi.org/10.1182/blood.V98.1.6

Published: 2001

Journal Articles

Development of human lymphohematopoietic stem and progenitor cells defined by expression of CD34 and CD81

Feng Ma, Mika Wada, Hiroshi Yoshino, Yasuhiro Ebihara, Takefumi Ishii, Atsushi Manabe, Ryuhei Tanaka, Taira Maekawa, Mamoru Ito, Hideo Mugishima, Shigetaka Asano, Tatsutoshi Nakahata, Kohichiro Tsuji

Blood (2001) 97 (12): 3755–3762.

https://doi.org/10.1182/blood.V97.12.3755

Published: 2001

NARROW

Acquired expression of Cbl Q367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia

A Comparison of Myelopoiesis from Induced Pluripotent Stem Cells with a Mutation in ELANE between Cyclic Neutropenia and Severe Congenital Neutropenia

Impaired Hematopoietic Differentiation of iPSCs Derived From Patients with FPD/AML

Suppressed Neutrophil Development in Hematopoiesis of Induced Pluripotent Stem Cells Derived From a Severe Congenital Neutropenia Patient with ELA2 Mutation

Matched HLA Haplotype Contributes to Reduce Sever Acute GVHD with Conserving GVL Effect in HLA-Mismatched Cord Blood Transplantation,

Low-Dose Cytosine Arabinoside Therapy for Neonates with Down Syndrome (DS) and Transient Leukemia (TL).

A Novel MBT-Containing Protein, Hemp, Plays Essential Roles In Skeletal Formation and Hematopoietic Stem Cell Function.

Differentiation of Mature Eosinophils From Human Embryonic and Induced Pluripotent Stem Cells.

Hematopoiesis of Human Induced Pluripotent Stem Cells Derived From Patients with Down Syndrome

Myelodysplastic Syndrome (MDS) and Myeloproliferative Disease (MPD) in Children: A Prospective Registration of 222 Cases

Clonal Analysis of Progressive Maturation of Erythroid Cells from Human Embryonic Stem Cell-Derived Definitive Hematopoiesis.

A Novel Method for Efficient Production of Multipotential Hematopoietic Progenitors from Human Embryonic Stem Cells by Co-Culture with Murine Fetal Liver-Derived Stromal Cells.

RAS-blocking bisphosphonate zoledronic acid inhibits the abnormal proliferation and differentiation of juvenile myelomonocytic leukemia cells in vitro

Bisphosphonate Zoledronic Acid (ZOL) Inhibits the Abnormal Proliferation and Differentiation of Juvenile Myelomonocytic Leukemia (JMML) Cells.

Erythropoiesis from acetyl LDL incorporating endothelial cells at the preliver stage

Impaired neutrophil maturation in truncated murine G-CSF receptor–transgenic mice

NOD/SCID/γ c null mouse: an excellent recipient mouse model for engraftment of human cells

Human granulocyte-macrophage colony-stimulating factor (hGM-CSF) stimulates primitive and definitive erythropoiesis in mouse embryos expressing hGM-CSF receptors but not erythropoietin receptors

Generation of definitive hematopoietic stem cells from murine early yolk sac and paraaortic splanchnopleures by aorta-gonad-mesonephros region–derived stromal cells

Development of human lymphohematopoietic stem and progenitor cells defined by expression of CD34 and CD81

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American Society of Hematology

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American Society of Hematology

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