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Journal Articles

Deciphering the Heterogeneity of Acute Myeloid Leukemia through Chromatin Accessibility Profiling

Blood (2024) 144 (Supplement 1): 639.

https://doi.org/10.1182/blood-2024-200415

Published: 2024

Journal Articles

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single-Cell Multi-Omics Sequencing

Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Ayana Kon, Masanori Motomura, Yotaro Ochi, Lanying Zhao, Koji Okazaki, June Takeda, Xingxing Qi, Akinori Yoda, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda, Seishi Ogawa

Blood (2024) 144 (Supplement 1): 5630.

https://doi.org/10.1182/blood-2024-210050

Published: 2024

Journal Articles

Epigenetic Classification of Acute Myeloid Leukemia Revealed By Genome-Wide Chromatin Profiling

Blood (2023) 142 (Supplement 1): 836.

https://doi.org/10.1182/blood-2023-180336

Published: 2023

Journal Articles

Germ line DDX41 mutations define a unique subtype of myeloid neoplasms

Hideki Makishima, Ryunosuke Saiki, Yasuhito Nannya, Sophia Korotev, Carmelo Gurnari, June Takeda, Yukihide Momozawa, Steve Best, Pramila Krishnamurthy, Tetsuichi Yoshizato, Yoshiko Atsuta, Yusuke Shiozawa, Yuka Iijima-Yamashita, Kenichi Yoshida, Yuichi Shiraishi, Yasunobu Nagata, Nobuyuki Kakiuchi, Makoto Onizuka, Kenichi Chiba, Hiroko Tanaka, Ayana Kon, Yotaro Ochi, Masahiro M. Nakagawa, Rurika Okuda, Takuto Mori, Akinori Yoda, Hidehiro Itonaga, Yasushi Miyazaki, Masashi Sanada, Takayuki Ishikawa, Shigeru Chiba, Hisashi Tsurumi, Senji Kasahara, Carsten Müller-Tidow, Akifumi Takaori-Kondo, Kazuma Ohyashiki, Toru Kiguchi, Fumihiko Matsuda, Joop H. Jansen, Chantana Polprasert, Piers Blombery, Yoichiro Kamatani, Satoru Miyano, Luca Malcovati, Torsten Haferlach, Michiaki Kubo, Mario Cazzola, Austin G. Kulasekararaj, Lucy A. Godley, Jaroslaw P. Maciejewski, Seishi Ogawa

Blood (2023) 141 (5): 534–549.

https://doi.org/10.1182/blood.2022018221

Published: 2023

Includes: Supplemental data

Journal Articles

Germline Risks and Clinical Impacts of DDX41 Mutations in Myeloid Malignancies

Hideki Makishima, Ryunosuke Saiki, Yasuhito Nannya, Sophia C. Korotev, Carmelo Gurnari, June Takeda, Yukihide Momozawa, Steve Best, Pramila Krishnamurthy, Tetsuichi Yoshizato, Yoshiko Atsuta, Yusuke Shiozawa, Yuka Iijima-Yamashita, Kenichi Yoshida, Yuichi Shiraishi, Yasunobu Nagata, Nobuyuki Kakiuchi, Makoto Onizuka, Kenichi Chiba, Hiroko Tanaka, Ayana Kon, Yotaro Ochi, Masahiro Marshall Nakagawa, Rurika Okuda, Takuto Mori, Akinori Yoda, Hidehiro Itonaga, Yasushi Miyazaki, Masashi Sanada, Takayuki Ishikawa, Shigeru Chiba, Hisashi Tsurumi, Senji Kasahara, Carsten Müller-Tidow, Akifumi Takaori-Kondo, Kazuma Ohyashiki, Toru Kiguchi, Fumihiko Matsuda, Joop H. Jansen, Chantana Polprasert, Piers Blombery, Yoichiro Kamatani, Satoru Miyano, Luca Malcovati, Torsten Haferlach, Michiaki Kubo, Mario Cazzola, Austin Kulasekararaj, Lucy A. Godley, Jaroslaw P. Maciejewski, Seishi Ogawa

Blood (2022) 140 (Supplement 1): 208–210.

https://doi.org/10.1182/blood-2022-158851

Published: 2022

Journal Articles

CTX-712, a Novel Splicing Modulator Targeting Myeloid Neoplasms

Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, Takuto Mori, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa

Blood (2022) 140 (Supplement 1): 489–490.

https://doi.org/10.1182/blood-2022-159338

Published: 2022

Journal Articles

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Masahiro Marshall Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Lanying Zhao, Yotaro Ochi, June Takeda, Qi Xingxing, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda, Seishi Ogawa

Blood (2022) 140 (Supplement 1): 2881–2882.

https://doi.org/10.1182/blood-2022-168149

Published: 2022

Journal Articles

Cooperative Effects of SRSF2 and STAG2 mutations on Development of Myelodysplastic Syndrome and Its Related Disorders

Blood (2022) 140 (Supplement 1): 4022–4023.

https://doi.org/10.1182/blood-2022-158748

Published: 2022

Journal Articles

Preclinical Translational Research Suggests a Clinical Trial Strategy for a Novel MALT1 Inhibitor ONO-7018/CTX-177 Against Malignant Lymphomas

Daisuke Morishita, Akio Mizutani, Hiroko Yamakawa, Yasuyoshi Arikawa, Hirokazu Tozaki, Takuro Kameda, Ayako Kamiunten, Keisuke Kataoka, Akinori Yoda, Yotaro Ochi, Kotaro Shide, Koji Izutsu, Yosuke Minami, Kazuya Shimoda, Seishi Ogawa

Blood (2022) 140 (Supplement 1): 8874–8875.

https://doi.org/10.1182/blood-2022-171019

Published: 2022

Journal Articles

CTX-712, a Novel Clk Inhibitor Targeting Myeloid Neoplasms with SRSF2 Mutation

Akinori Yoda, Daisuke Morishita, Yotaro Ochi, Akio Mizutani, June Takeda, Hirokazu Tozaki, Yoshihiko Satoh, Yasuhito Nannya, Hideki Makishima, Hiroshi Miyake, Seishi Ogawa

Blood (2021) 138 (Supplement 1): 205.

https://doi.org/10.1182/blood-2021-148205

Published: 2021

Journal Articles

EPOR/JAK/STAT Signaling Pathway As Therapeutic Target of Acute Erythroid Leukemia

Blood (2021) 138 (Supplement 1): 610.

https://doi.org/10.1182/blood-2021-152800

Published: 2021

Journal Articles

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Blood (2021) 138 (Supplement 1): 1092.

https://doi.org/10.1182/blood-2021-152219

Published: 2021

Journal Articles

Analysis of Clonal Evolution of AML Using Simultaneous Single-Cell DNA/RNA Analysis

Ryosaku Inagaki, MSc, Masahiro Marshall Nakagawa, MDPhD, Yasuhito Nannya, MD PhD, Qi Xingxing, PhD, Lanying Zhao, MD, PhD, June Takeda, MD, Akinori Yoda, PhD, Ayana Kon, MD PhD, Hisashi Tsurumi, MD PhD, Hideki Makishima, MD PhD, Seishi Ogawa, MD PhD

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-143320

Published: 2020

Journal Articles

Genotype-Phenotype Relationships and Therapeutic Targets in Acute Erythroid Leukemia

June Takeda, MD, Kenichi Yoshida, MDPhD, Akinori Yoda, PhD, Lee-Yung Shih, MD, Yasuhito Nannya, MD PhD, Yotaro Ochi, MD, Ayana Kon, MD PhD, Kenichi Chiba, Yuichi Shiraishi, PhD, Yusuke Shiozawa, MD PhD, Tetsuichi Yoshizato, MD PhD, Cassandra M Kerr, MS, Yasunobu Nagata, MD PhD, Toshiyuki Kitano, MD PhD, Akira Hangaishi, MD PhD, Ken Ishiyama, MD PhD, Hisashi Tsurumi, MD PhD, Yasushi Miyazaki, MD PhD, Nobuhiro Hiramoto, MD, Takayuki Ishikawa, MD PhD, Masahiro Marshall Nakagawa, MDPhD, Akifumi Takaori-Kondo, MD PhD, Shigeru Chiba, MD PhD, Hideyuki Nakazawa, MD PhD, Ming-Chung Kuo, MD, Keisuke Kataoka, MD PhD, Ryunosuke Saiki, MD, Hiroko Tanaka, Kensuke Usuki, MD PhD, Shuichi Miyawaki, MD PhD, Satoru Miyano, PhD, Jaroslaw P. Maciejewski, MD PhD, Arnold Ganser, Michael Heuser, Prof., MD, Felicitas Thol, Hideki Makishima, MD PhD, Seishi Ogawa, MD PhD

Blood (2020) 136 (Supplement 1): 17–18.

https://doi.org/10.1182/blood-2020-141750

Published: 2020

Journal Articles

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Masahiro Marshall Nakagawa, MDPhD, Ryosaku Inagaki, MSc, Yutaka Kuroda, MD, PhD, Yasuhito Nannya, MD PhD, Lanying Zhao, MD, PhD, Yotaro Ochi, MD, June Takeda, MD, Qi Xingxing, PhD, Akinori Yoda, PhD, Ayana Kon, MD PhD, Nobuyuki Kakiuchi, MD, Hideki Makishima, MD PhD, Shuichi Matsuda, MD, PhD, Seishi Ogawa, MD PhD

Blood (2020) 136 (Supplement 1): 34.

https://doi.org/10.1182/blood-2020-142157

Published: 2020

Journal Articles

Preclinical Evaluation of a Novel MALT1 Inhibitor CTX-177 for Relapse/Refractory Lymphomas

Daisuke Morishita, PhD, Akio Mizutani, PhD, Hirokazu Tozaki, PhD, Yasuyoshi Arikawa, PhD, Takuro Kameda, MD PhD, Ayako Kamiunten, MD, Keisuke Kataoka, MD PhD, Akinori Yoda, PhD, Yotaro Ochi, MD, Kotaro Shide, MD PhD, Koji Izutsu, MD PhD, Yosuke Minami, MDPhD, Kazuya Shimoda, MD PhD, Hiroshi Miyake, PhD, Seishi Ogawa, MD PhD

Blood (2020) 136 (Supplement 1): 3–4.

https://doi.org/10.1182/blood-2020-141824

Published: 2020

Journal Articles

Genomic landscape of young ATLL patients identifies frequent targetable CD28 fusions

Noriaki Yoshida, Kay Shigemori, Nicholas Donaldson, Christopher Trevisani, Nicolas A. Cordero, Kristen E. Stevenson, Xia Bu, Fumiko Arakawa, Mai Takeuchi, Koichi Ohshima, Akinori Yoda, Samuel Y. Ng, David M. Weinstock

Blood (2020) 135 (17): 1467–1471.

https://doi.org/10.1182/blood.2019001815

Published: 2020

Includes: Supplemental data

Journal Articles

CTX-712, a Novel Clk Inhibitor Targeting Myeloid Neoplasms with SRSF2 Mutation

Akinori Yoda, PhD, Daisuke Morishita, PhD, Akio Mizutani, PhD, Yoshihiko Satoh, PhD, Yotaro Ochi, MD, Yasuhito Nannya, MD PhD, Hideki Makishima, MD PhD, Hiroshi Miyake, PhD, Seishi Ogawa, MD PhD

Blood (2019) 134 (Supplement_1): 404.

https://doi.org/10.1182/blood-2019-131559

Published: 2019

Journal Articles

Analysis of Mechanisms Underlying Clonal Evolution of AML By a New Single-Cell Sequencing Platform

Ryosaku Inagaki, MSc, Masahiro Marshall Nakagawa, MD PhD, Yasuhito Nannya, MD PhD, Qi Xingxing, PhD, Lanying Zhao, MD, PhD, June Takeda, MD, Akinori Yoda, PhD, Ayana Kon, MD PhD, Hisashi Tsurumi, MD PhD, Hideki Makishima, MD PhD, Seishi Ogawa, MD PhD

Blood (2019) 134 (Supplement_1): 542.

https://doi.org/10.1182/blood-2019-126444

Published: 2019

Journal Articles

Genomic Landscape of Young ATLL Patients Identifies Frequent Targetable CD28 Fusions

Noriaki Yoshida, MD PhD, Kay Shigemori, Samuel Y. Ng, MD PhD, Ajit Nirmal, PhD, Nicolas Donaldson, Nicolas Cordero, Kristen E. Stevenson, MS, Xia Bu, Mai Takeuchi, MD PhD, Koichi Ohshima, MD PhD, Akinori Yoda, PhD, David M Weinstock

Blood (2019) 134 (Supplement_1): 2760.

https://doi.org/10.1182/blood-2019-122525

Published: 2019

NARROW

Deciphering the Heterogeneity of Acute Myeloid Leukemia through Chromatin Accessibility Profiling

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single-Cell Multi-Omics Sequencing

Epigenetic Classification of Acute Myeloid Leukemia Revealed By Genome-Wide Chromatin Profiling

Germ line DDX41 mutations define a unique subtype of myeloid neoplasms

Germline Risks and Clinical Impacts of DDX41 Mutations in Myeloid Malignancies

CTX-712, a Novel Splicing Modulator Targeting Myeloid Neoplasms

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Cooperative Effects of SRSF2 and STAG2 mutations on Development of Myelodysplastic Syndrome and Its Related Disorders

Preclinical Translational Research Suggests a Clinical Trial Strategy for a Novel MALT1 Inhibitor ONO-7018/CTX-177 Against Malignant Lymphomas

CTX-712, a Novel Clk Inhibitor Targeting Myeloid Neoplasms with SRSF2 Mutation

EPOR/JAK/STAT Signaling Pathway As Therapeutic Target of Acute Erythroid Leukemia

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Analysis of Clonal Evolution of AML Using Simultaneous Single-Cell DNA/RNA Analysis

Genotype-Phenotype Relationships and Therapeutic Targets in Acute Erythroid Leukemia

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Preclinical Evaluation of a Novel MALT1 Inhibitor CTX-177 for Relapse/Refractory Lymphomas

Genomic landscape of young ATLL patients identifies frequent targetable CD28 fusions

CTX-712, a Novel Clk Inhibitor Targeting Myeloid Neoplasms with SRSF2 Mutation

Analysis of Mechanisms Underlying Clonal Evolution of AML By a New Single-Cell Sequencing Platform

Genomic Landscape of Young ATLL Patients Identifies Frequent Targetable CD28 Fusions

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American Society of Hematology

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