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Journal Articles

Pathogenic Mechanisms of DDX41 Mutations in the Development of Myeloid Malignancies

Ayana Kon, Masahiro Marshall Nakagawa, Keisuke Kataoka, Nobuyuki Kakiuchi, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa

Blood (2023) 142 (Supplement 1): 952.

https://doi.org/10.1182/blood-2023-184519

Published: 2023

Journal Articles

Epigenetic Classification of Acute Myeloid Leukemia Revealed By Genome-Wide Chromatin Profiling

Blood (2023) 142 (Supplement 1): 836.

https://doi.org/10.1182/blood-2023-180336

Published: 2023

Journal Articles

Long-Term Clonal Inversion in an MDS-RS Case with Dual SF3B1 Mutations

Pedro Luis Moura, Isabel Juliana F Hofman, Yasuhito Nannya, Affaf Aliouat, Teresa Mortera-Blanco, Tetsuichi Yoshizato, Ryunosuke Saiki, Masahiro Marshall Nakagawa, Ann-Charlotte Björklund, Gunilla Walldin, Indira Barbosa, Monika Jansson, Francesca Grasso, Maria Creignou, Edda Maria Elvarsdottir, Petter S Woll, Sten Eirik Waelgaard Jacobsen, Seishi Ogawa, Eva Hellström-Lindberg

Blood (2022) 140 (Supplement 1): 6898–6899.

https://doi.org/10.1182/blood-2022-158447

Published: 2022

Journal Articles

Cooperative Effects of SRSF2 and STAG2 mutations on Development of Myelodysplastic Syndrome and Its Related Disorders

Blood (2022) 140 (Supplement 1): 4022–4023.

https://doi.org/10.1182/blood-2022-158748

Published: 2022

Journal Articles

Germline Risks and Clinical Impacts of DDX41 Mutations in Myeloid Malignancies

Hideki Makishima, Ryunosuke Saiki, Yasuhito Nannya, Sophia C. Korotev, Carmelo Gurnari, June Takeda, Yukihide Momozawa, Steve Best, Pramila Krishnamurthy, Tetsuichi Yoshizato, Yoshiko Atsuta, Yusuke Shiozawa, Yuka Iijima-Yamashita, Kenichi Yoshida, Yuichi Shiraishi, Yasunobu Nagata, Nobuyuki Kakiuchi, Makoto Onizuka, Kenichi Chiba, Hiroko Tanaka, Ayana Kon, Yotaro Ochi, Masahiro Marshall Nakagawa, Rurika Okuda, Takuto Mori, Akinori Yoda, Hidehiro Itonaga, Yasushi Miyazaki, Masashi Sanada, Takayuki Ishikawa, Shigeru Chiba, Hisashi Tsurumi, Senji Kasahara, Carsten Müller-Tidow, Akifumi Takaori-Kondo, Kazuma Ohyashiki, Toru Kiguchi, Fumihiko Matsuda, Joop H. Jansen, Chantana Polprasert, Piers Blombery, Yoichiro Kamatani, Satoru Miyano, Luca Malcovati, Torsten Haferlach, Michiaki Kubo, Mario Cazzola, Austin Kulasekararaj, Lucy A. Godley, Jaroslaw P. Maciejewski, Seishi Ogawa

Blood (2022) 140 (Supplement 1): 208–210.

https://doi.org/10.1182/blood-2022-158851

Published: 2022

Journal Articles

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Masahiro Marshall Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Lanying Zhao, Yotaro Ochi, June Takeda, Qi Xingxing, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda, Seishi Ogawa

Blood (2022) 140 (Supplement 1): 2881–2882.

https://doi.org/10.1182/blood-2022-168149

Published: 2022

Journal Articles

EPOR/JAK/STAT Signaling Pathway As Therapeutic Target of Acute Erythroid Leukemia

Blood (2021) 138 (Supplement 1): 610.

https://doi.org/10.1182/blood-2021-152800

Published: 2021

Journal Articles

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Blood (2021) 138 (Supplement 1): 1092.

https://doi.org/10.1182/blood-2021-152219

Published: 2021

Journal Articles

Functional Roles of DDX41 Mutations in the Development of Myeloid Malignancies

Ayana Kon, Masahiro Marshall Nakagawa, Keisuke Kataoka, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa

Blood (2021) 138 (Supplement 1): 150.

https://doi.org/10.1182/blood-2021-152269

Published: 2021

Journal Articles

Analysis of Clonal Evolution of AML Using Simultaneous Single-Cell DNA/RNA Analysis

Ryosaku Inagaki, MSc, Masahiro Marshall Nakagawa, MDPhD, Yasuhito Nannya, MD PhD, Qi Xingxing, PhD, Lanying Zhao, MD, PhD, June Takeda, MD, Akinori Yoda, PhD, Ayana Kon, MD PhD, Hisashi Tsurumi, MD PhD, Hideki Makishima, MD PhD, Seishi Ogawa, MD PhD

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-143320

Published: 2020

Journal Articles

Genotype-Phenotype Relationships and Therapeutic Targets in Acute Erythroid Leukemia

June Takeda, MD, Kenichi Yoshida, MDPhD, Akinori Yoda, PhD, Lee-Yung Shih, MD, Yasuhito Nannya, MD PhD, Yotaro Ochi, MD, Ayana Kon, MD PhD, Kenichi Chiba, Yuichi Shiraishi, PhD, Yusuke Shiozawa, MD PhD, Tetsuichi Yoshizato, MD PhD, Cassandra M Kerr, MS, Yasunobu Nagata, MD PhD, Toshiyuki Kitano, MD PhD, Akira Hangaishi, MD PhD, Ken Ishiyama, MD PhD, Hisashi Tsurumi, MD PhD, Yasushi Miyazaki, MD PhD, Nobuhiro Hiramoto, MD, Takayuki Ishikawa, MD PhD, Masahiro Marshall Nakagawa, MDPhD, Akifumi Takaori-Kondo, MD PhD, Shigeru Chiba, MD PhD, Hideyuki Nakazawa, MD PhD, Ming-Chung Kuo, MD, Keisuke Kataoka, MD PhD, Ryunosuke Saiki, MD, Hiroko Tanaka, Kensuke Usuki, MD PhD, Shuichi Miyawaki, MD PhD, Satoru Miyano, PhD, Jaroslaw P. Maciejewski, MD PhD, Arnold Ganser, Michael Heuser, Prof., MD, Felicitas Thol, Hideki Makishima, MD PhD, Seishi Ogawa, MD PhD

Blood (2020) 136 (Supplement 1): 17–18.

https://doi.org/10.1182/blood-2020-141750

Published: 2020

Journal Articles

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Masahiro Marshall Nakagawa, MDPhD, Ryosaku Inagaki, MSc, Yutaka Kuroda, MD, PhD, Yasuhito Nannya, MD PhD, Lanying Zhao, MD, PhD, Yotaro Ochi, MD, June Takeda, MD, Qi Xingxing, PhD, Akinori Yoda, PhD, Ayana Kon, MD PhD, Nobuyuki Kakiuchi, MD, Hideki Makishima, MD PhD, Shuichi Matsuda, MD, PhD, Seishi Ogawa, MD PhD

Blood (2020) 136 (Supplement 1): 34.

https://doi.org/10.1182/blood-2020-142157

Published: 2020

Journal Articles

Functional Characterization of Compound DDX41 Germline and Somatic R525H Mutations in the Development of Myeloid Malignancies

Ayana Kon, MD PhD, Masahiro Marshall Nakagawa, MDPhD, Ryosaku Inagaki, MSc, Keisuke Kataoka, MD PhD, Hideki Makishima, MD PhD, Yotaro Ochi, MD, Manabu Nakayama, PhD, Haruhiko Koseki, MD PhD, Yasuhito Nannya, MD PhD, Seishi Ogawa, MD PhD

Blood (2020) 136 (Supplement 1): 21–22.

https://doi.org/10.1182/blood-2020-143318

Published: 2020

Journal Articles

Analysis of Mechanisms Underlying Clonal Evolution of AML By a New Single-Cell Sequencing Platform

Ryosaku Inagaki, MSc, Masahiro Marshall Nakagawa, MD PhD, Yasuhito Nannya, MD PhD, Qi Xingxing, PhD, Lanying Zhao, MD, PhD, June Takeda, MD, Akinori Yoda, PhD, Ayana Kon, MD PhD, Hisashi Tsurumi, MD PhD, Hideki Makishima, MD PhD, Seishi Ogawa, MD PhD

Blood (2019) 134 (Supplement_1): 542.

https://doi.org/10.1182/blood-2019-126444

Published: 2019

Journal Articles

Analysis of Clonal Evolution/Heterogeneity of MDS By Simultaneous Detection of Both Mutation and Gene Expression By Single Cell Sequencing

Masahiro Marshall Nakagawa, MDPhD, Ryosaku Inagaki, Yasuhito Nannya, MD PhD, Lanying Zhao, MD, PhD, Yutaka Kuroda, MD, PhD, June Takeda, MD, Xingxing Qi, Akinori Yoda, PhD, Ayana Kon, MD PhD, Hisashi Tsurumi, MD PhD, Hideki Makishima, MD PhD, Shuichi Matsuda, MD, PhD, Seishi Ogawa, MD PhD

Blood (2018) 132 (Supplement 1): 1800.

https://doi.org/10.1182/blood-2018-99-116448

Published: 2018

Journal Articles

Novel and Significant Impact of Germline Variants Predisposed to Pathogenic Somatic Mutations and Loss of Heterozygosity (LOH) in Myelodysplastic Syndromes (MDS) and Clonal Hematopoiesis of Indeterminate Potential (CHIP)

Blood (2018) 132 (Supplement 1): 108.

https://doi.org/10.1182/blood-2018-99-118833

Published: 2018

Journal Articles

DNA Methylation and Genetic Profiles in 320 Patients with Myelodysplastic Syndromes

Blood (2018) 132 (Supplement 1): 1799.

https://doi.org/10.1182/blood-2018-99-116489

Published: 2018

Journal Articles

Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice

Ayana Kon, Satoshi Yamazaki, Yasuhito Nannya, Keisuke Kataoka, Yasunori Ota, Masahiro Marshall Nakagawa, Kenichi Yoshida, Yusuke Shiozawa, Maiko Morita, Tetsuichi Yoshizato, Masashi Sanada, Manabu Nakayama, Haruhiko Koseki, Hiromitsu Nakauchi, Seishi Ogawa

Blood (2018) 131 (6): 621–635.

https://doi.org/10.1182/blood-2017-01-762393

Published: 2018

Includes: Supplemental data

Journal Articles

Stag2 regulates Hematopoietic Differentiation and Self-Renewal

Yotaro Ochi, MD, Ayana Kon, MD PhD, Kenichi Yoshida, MD PhD, Keisuke Kataoka, Masahiro Marshall Nakagawa, Hideki Makishima, MD,PhD,FACP., Manabu Nakayama, Haruhiko Koseki, Akifumi Takaori-Kondo, MD PhD, Seishi Ogawa, MD PhD

Blood (2017) 130 (Supplement 1): 790.

https://doi.org/10.1182/blood.V130.Suppl_1.790.790

Published: 2017

Journal Articles

Targeting the Osteoblast in Myelodysplasia and Acute Myeloid Leukemia

Masahiro Marshall Nakagawa, Aruna Kode, Sanil J Manavalan, Govind Bhagat, MD, Julie Teruya-Feldstein, MD, Azra Raza, MD, Ellin Berman, MD, Stavroula Kousteni

Blood (2015) 126 (23): 2551.

https://doi.org/10.1182/blood.V126.23.2551.2551

Published: 2015

NARROW

Pathogenic Mechanisms of DDX41 Mutations in the Development of Myeloid Malignancies

Epigenetic Classification of Acute Myeloid Leukemia Revealed By Genome-Wide Chromatin Profiling

Long-Term Clonal Inversion in an MDS-RS Case with Dual SF3B1 Mutations

Cooperative Effects of SRSF2 and STAG2 mutations on Development of Myelodysplastic Syndrome and Its Related Disorders

Germline Risks and Clinical Impacts of DDX41 Mutations in Myeloid Malignancies

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

EPOR/JAK/STAT Signaling Pathway As Therapeutic Target of Acute Erythroid Leukemia

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Functional Roles of DDX41 Mutations in the Development of Myeloid Malignancies

Analysis of Clonal Evolution of AML Using Simultaneous Single-Cell DNA/RNA Analysis

Genotype-Phenotype Relationships and Therapeutic Targets in Acute Erythroid Leukemia

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Functional Characterization of Compound DDX41 Germline and Somatic R525H Mutations in the Development of Myeloid Malignancies

Analysis of Mechanisms Underlying Clonal Evolution of AML By a New Single-Cell Sequencing Platform

Analysis of Clonal Evolution/Heterogeneity of MDS By Simultaneous Detection of Both Mutation and Gene Expression By Single Cell Sequencing

Novel and Significant Impact of Germline Variants Predisposed to Pathogenic Somatic Mutations and Loss of Heterozygosity (LOH) in Myelodysplastic Syndromes (MDS) and Clonal Hematopoiesis of Indeterminate Potential (CHIP)

DNA Methylation and Genetic Profiles in 320 Patients with Myelodysplastic Syndromes

Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice

Stag2 regulates Hematopoietic Differentiation and Self-Renewal

Targeting the Osteoblast in Myelodysplasia and Acute Myeloid Leukemia

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American Society of Hematology

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American Society of Hematology

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