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Tom Erkers
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Journal Articles

Resistance to FLT3 Inhibitors in FLT3-Mutated AML Is Associated with CD45RA + CD200 - leukemic Cells and Can be Overcome By Combination with SMAC Mimetics

Nona Struyf, Henrik Gezelius, Anders Lundmark, Chiara Barizza, Hidde Ploeger, Lucía Rico Pizarro, Mattias Vesterlund, Georgios Mermelekas, Albin Osterroos, Anna Bohlin, Sofia Bengtzén, Kerstin Hamberg Levedahl, Rozbeh Jafari, Lukas M Orre, Janne Lehtiö, Päivi Östling, Brinton Seashore-Ludlow, Jessica Nordlund, Soren Lehmann, Olli Kallioniemi, Tom Erkers
Journal: Blood
Blood (2024) 144 (Supplement 1): 1565.
https://doi.org/10.1182/blood-2024-200093
Published: 2024
Journal Articles

Deciphering the Heterogeneity of Acute Myeloid Leukemia through Chromatin Accessibility Profiling

Yotaro Ochi, Markus Liew-Littorin, Yasuhito Nannya, Sofia Bengtzén, Petar Antunovic, Stefan Deneberg, Martin Jadersten, Vladimir Lazarevic, Bertil Uggla, Lovisa Wennström, Emma Olander, Senji Kasahara, Nobuhiro Hiramoto, Nobuhiro Kanemura, Nobuo Sezaki, Maki Sakurada, Makoto Iwasaki, Junya Kanda, Yasunori Ueda, Satoshi Yoshihara, Tom Erkers, Nona Struyf, Masanori Motomura, Masahiro M Nakagawa, Ryunosuke Saiki, Hidehito Fukushima, Koji Okazaki, Akinori Yoda, Rurika Okuda, Guoxiang Xie, Albin Osterroos, Lanying Zhao, Yuichi Shiraishi, Takayuki Ishikawa, Satoru Miyano, Hiroshi I Suzuki, Akifumi Takaori-Kondo, Olli Kallioniemi, Gunnar Juliusson, Martin Höglund, Soren Lehmann, Seishi Ogawa
Journal: Blood
Blood (2024) 144 (Supplement 1): 639.
https://doi.org/10.1182/blood-2024-200415
Published: 2024
Journal Articles

Computational Approach Based on Independent Drug Action Identifies Clinically Relevant Combinations for Acute Myeloid Leukemia

Xiao Xian Lin, Vedant Sandhu, Christopher A. Eide, Stephen E. Kurtz, Disha Malani, Tom Erkers, Olli Kallioniemi, Jeffrey W Tyner, Shruti Bhatt
Journal: Blood
Blood (2023) 142 (Supplement 1): 5015.
https://doi.org/10.1182/blood-2023-188731
Published: 2023
Journal Articles

Comparison of Data from Fresh and Frozen AML Samples for Functional Drug Testing

Nona Struyf, Cornelia Arnroth, Stephanie Sunandar, Anna Bohlin, Sofia Bengtzén, Sören Lehmann, Olli Kallioniemi, Päivi Östling, Brinton Seashore-Ludlow, Tom Erkers
Journal: Blood
Blood (2022) 140 (Supplement 1): 6290.
https://doi.org/10.1182/blood-2022-157262
Published: 2022
Journal Articles

Data-Driven Molecular Hallmarks of Acute Myeloid Leukemia: Biological, Prognostic and Therapeutic Implications

Tom Erkers, Francesco Marabita, Nona Struyf, Mattias Vesterlund, Tojo James, Cornelia Arnroth, Anna Bohlin, Sofia Bengtzén, Albin Österroos, Matthias Stahl, Rozbeh Jafari, Lukas Orre, Yudi Pawitan, Brinton Seashore-Ludlow, Janne Lehtiö, Sören Lehmann, Päivi Östling, Olli Kallioniemi
Journal: Blood
Blood (2022) 140 (Supplement 1): 6299.
https://doi.org/10.1182/blood-2022-163046
Published: 2022
Journal Articles

High-parametric evaluation of human invariant natural killer T cells to delineate heterogeneity in allo- and autoimmunity

Tom Erkers, Bryan J. Xie, Laura J. Kenyon, Brian Smith, Mary Rieck, Kent P. Jensen, Xuhuai Ji, Marina Basina, Samuel Strober, Robert S. Negrin, Holden T. Maecker, Everett H. Meyer
Journal: Blood
Blood (2020) 135 (11): 814–825.
https://doi.org/10.1182/blood.2019001903
Published: 2020
Includes: Supplemental data
Journal Articles

High-Throughput Functional Ex-Vivo Drug Testing and Multi-Omics Profiling in Patients with Acute Myeloid Leukemia

Tom Erkers, PhD, Brinton Seashore-Ludlow, Nona Struyf, Francesco Marabita, Tojo James, Disha Malani, Mattias Vesterlund, Matthias Stalhl, Yudi Pawitan, Sören Lehmann, MD PhD, Päivi Östling, Janne Lehtiö, Olli Kallioniemi
Journal: Blood
Blood (2019) 134 (Supplement_1): 4641.
https://doi.org/10.1182/blood-2019-124332
Published: 2019
Journal Articles

A Proinflammatory Invariant Natural Killer T Cells Phenotypic State Associates with Human Graft-Versus-Host Disease Onset and Response

Tom Erkers, PhD, Bryan Xei, BS, Laura Kenyon, Mary Rieck, BS, Marina Basina, MD, Kent Jensen, PhD, Samuel Strober, MD, Robert S. Negrin, MD, Holden T. Maecker, PhD, Everett H Meyer, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2111.
https://doi.org/10.1182/blood-2018-99-120358
Published: 2018
Journal Articles

The Use of Monoclonal Antibody Directed Chimeric Antigen Receptors to Facilitate Conventional T Cell and Treg Control of GvHD and Tissue Tolerance in Murine Models

Antonio Pierini, MD, Bettina Iliopoulou, PhD, Heshan Peiris, PhD, Magdiel Perez Cruz, PhD, Jeanette Baker, PhD, Katie Hsu, PhD, William Strober, Ping-Ping Zheng, PhD, Tom Erkers, PhD, Aaron Ring, MD PhD, Andrea Velardi, Robert S. Negrin, MD, Seung Kim, MD PhD, Everett Meyer, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3355.
https://doi.org/10.1182/blood.V128.22.3355.3355
Published: 2016