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Yukiko Komeno
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Journal Articles

Usp18 Is Required for Normal Stem Cell Maintenance

Kei-ichiro Arimoto, PhD, Yue Zhang, Ming Yan, PhD, Sayuri Miyauchi, DDS, PhD, Stephanie Weng, PhD, Samuel A. Stoner, Takahiro Shima, MD PhD, Yukiko Komeno, MD PhD, Kentson Lam, MD PhD, Dong-Er Zhang, PhD
Journal: Blood
Blood (2016) 128 (22): 3863.
https://doi.org/10.1182/blood.V128.22.3863.3863
Published: 2016
Journal Articles

Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells

Fumio Nakahara, Jiro Kitaura, Tomoyuki Uchida, Chiemi Nishida, Katsuhiro Togami, Daichi Inoue, Toshihiro Matsukawa, Yuki Kagiyama, Yutaka Enomoto, Kimihito C. Kawabata, Lai Chen-Yi, Yukiko Komeno, Kumi Izawa, Toshihiko Oki, Genta Nagae, Yuka Harada, Hironori Harada, Makoto Otsu, Hiroyuki Aburatani, Beate Heissig, Koichi Hattori, Toshio Kitamura
Journal: Blood
Blood (2014) 123 (25): 3932–3942.
https://doi.org/10.1182/blood-2013-01-476747
Published: 2014
Includes: Supplemental data
Journal Articles

Runx1 exon 6–related alternative splicing isoforms differentially regulate hematopoiesis in mice

Yukiko Komeno, Ming Yan, Shinobu Matsuura, Kentson Lam, Miao-Chia Lo, Yi-Jou Huang, Daniel G. Tenen, James R. Downing, Dong-Er Zhang
Journal: Blood
Blood (2014) 123 (24): 3760–3769.
https://doi.org/10.1182/blood-2013-08-521252
Published: 2014
Includes: Supplemental data
Journal Articles

SRSF2 Is Essential For Hematopoiesis and Its Mutations Dysregulate Alternative RNA Splicing In MDS

Yukiko Komeno, MD, PhD, Jinsong Qiu, PhD, Leo Lin, BS, YiJun Xu, BS, Felicitas Thol, MD, Dora D Monterroza, Russell Dekelver, Liang Chen, PhD, Michael Heuser, MD, Xiang-Dong Fu, PhD, Dong-Er Zhang, PhD
Journal: Blood
Blood (2013) 122 (21): 261.
https://doi.org/10.1182/blood.V122.21.261.261
Published: 2013
Journal Articles

Expression of the runt homology domain of RUNX1 disrupts homeostasis of hematopoietic stem cells and induces progression to myelodysplastic syndrome

Shinobu Matsuura, Yukiko Komeno, Kristen E. Stevenson, Joseph R. Biggs, Kentson Lam, Tingdong Tang, Miao-Chia Lo, Xiuli Cong, Ming Yan, Donna S. Neuberg, Dong-Er Zhang
Journal: Blood
Blood (2012) 120 (19): 4028–4037.
https://doi.org/10.1182/blood-2012-01-404533
Published: 2012
Includes: Supplemental data
Journal Articles

Combined gene expression and DNA occupancy profiling identifies potential therapeutic targets of t(8;21) AML

Miao-Chia Lo, Luke F. Peterson, Ming Yan, Xiuli Cong, Fulai Jin, Wei-Jong Shia, Shinobu Matsuura, Eun-Young Ahn, Yukiko Komeno, Minh Ly, Hans B. Ommen, I-Ming Chen, Peter Hokland, Cheryl L. Willman, Bing Ren, Dong-Er Zhang
Journal: Blood
Blood (2012) 120 (7): 1473–1484.
https://doi.org/10.1182/blood-2011-12-395335
Published: 2012
Includes: Supplemental data
Journal Articles

PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential

Wei-Jong Shia, Akiko J. Okumura, Ming Yan, Ali Sarkeshik, Miao-Chia Lo, Shinobu Matsuura, Yukiko Komeno, Xinyang Zhao, Stephen D. Nimer, John R. Yates, III, Dong-Er Zhang
Journal: Blood
Blood (2012) 119 (21): 4953–4962.
https://doi.org/10.1182/blood-2011-04-347476
Published: 2012
Includes: Supplemental data
Journal Articles

“RUNX1-IRES-GFP Knock-in” Mice Lack Expression of Runx1a: A Versatile Tool for Hematopoietic Stem Cell Analysis

Yukiko Komeno, MD, PhD, Ming Yan, PhD, Shinobu Matsuura, DVM, PhD, Miao-Chia Lo, PhD, James R. Downing, MD, Dong-Er Zhang, PhD
Journal: Blood
Blood (2011) 118 (21): 2329.
https://doi.org/10.1182/blood.V118.21.2329.2329
Published: 2011
Journal Articles

PRMT1 Interacts with AML1-ETO to Promote Its Transcriptional Activation and Progenitor Cell Proliferative Potential

Wei-Jong Shia, PhD, Akiko J. Okumura, PhD, Ming Yan, PhD, Ali Sarkeshik, Miao-Chia Lo, PhD, Shinobu Matsuura, DVM, PhD, Yukiko Komeno, MD, PhD, Xinyang Zhao, PhD, Stephen D. Nimer, MD, John R. Yates, III, PhD, Dong-Er Zhang, PhD
Journal: Blood
Blood (2011) 118 (21): 4621.
https://doi.org/10.1182/blood.V118.21.4621.4621
Published: 2011
Journal Articles

Two types of C/EBPα mutations play distinct but collaborative roles in leukemogenesis: lessons from clinical data and BMT models

Naoko Kato, Jiro Kitaura, Noriko Doki, Yukiko Komeno, Naoko Watanabe-Okochi, Katsuhiro Togami, Fumio Nakahara, Toshihiko Oki, Yutaka Enomoto, Yumi Fukuchi, Hideaki Nakajima, Yuka Harada, Hironori Harada, Toshio Kitamura
Journal: Blood
Blood (2011) 117 (1): 221–233.
https://doi.org/10.1182/blood-2010-02-270181
Published: 2011
Includes: Supplemental data
Journal Articles

Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia

Fumio Nakahara, Mamiko Sakata-Yanagimoto, Yukiko Komeno, Naoko Kato, Tomoyuki Uchida, Kyoko Haraguchi, Keiki Kumano, Yuka Harada, Hironori Harada, Jiro Kitaura, Seishi Ogawa, Mineo Kurokawa, Toshio Kitamura, Shigeru Chiba
Journal: Blood
Blood (2010) 115 (14): 2872–2881.
https://doi.org/10.1182/blood-2009-05-222836
Published: 2010
Includes: Supplemental data
Journal Articles

Enhanced expression of p210BCR/ABL and aberrant expression of Zfp423/ZNF423 induce blast crisis of chronic myelogenous leukemia

Kazuko Miyazaki, Norimasa Yamasaki, Hideaki Oda, Takeshi Kuwata, Yohei Kanno, Masaki Miyazaki, Yukiko Komeno, Jiro Kitaura, Zen-ichiro Honda, Søren Warming, Nancy A. Jenkins, Neal G. Copeland, Toshio Kitamura, Takuro Nakamura, Hiroaki Honda
Journal: Blood
Blood (2009) 113 (19): 4702–4710.
https://doi.org/10.1182/blood-2007-05-088724
Published: 2009
Includes: Supplemental data
Journal Articles

AML1 mutations induced MDS and MDS/AML in a mouse BMT model

Naoko Watanabe-Okochi, Jiro Kitaura, Ryoichi Ono, Hironori Harada, Yuka Harada, Yukiko Komeno, Hideaki Nakajima, Tetsuya Nosaka, Toshiya Inaba, Toshio Kitamura
Journal: Blood
Blood (2008) 111 (8): 4297–4308.
https://doi.org/10.1182/blood-2007-01-068346
Published: 2008
Includes: Supplemental data
Journal Articles

Single Oral Administration of KRN383, a Novel Flt3 Inhibitor, Induces Eradication of the Xenograft Tumor Harboring Flt3 Mutation in Mice.

Uichi Nishiyama, Masako Ozai, Rieko Yoshioka, Tetsuya Yoshino, Yuko Ogasawara, Miyuki Kitahori, Eiji Yoshioka, Kazuo Kubo, Yukiko Komeno, MD, Mineo Kurokawa, MD, PhD, Seishi Ogawa, MD, PhD, Shigeru Chiba, MD, PhD, Tatsushi Osawa, PhD, Tomoaki Kuwaki, Hisamaru Hirai, MD, PhD, Atsushi Miwa, PhD
Journal: Blood
Blood (2004) 104 (11): 2545.
https://doi.org/10.1182/blood.V104.11.2545.2545
Published: 2004
Journal Articles

Ki23819 (KRN383•HCl) Inhibits Kinase Activity of Wild Type and Mutant FLT3 Receptor Tyrosine Kinase In Vitro .

Yukiko Komeno, Mineo Kurokawa, Yoichi Imai, Masataka Takeshita, Tomoko Matsumura, Kazuo Kubo, Tetsuya Yoshino, Uichi Nishiyama, Tomoaki Kuwaki, Kinya Kubo, Tatsushi Osawa, Seishi Ogawa, Shigeru Chiba, Atsushi Miwa, Hisamaru Hirai
Journal: Blood
Blood (2004) 104 (11): 1168.
https://doi.org/10.1182/blood.V104.11.1168.1168
Published: 2004