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Journal Articles

Clonal Hematopoiesis Evolves into Dendritic Cell Neoplasm through the Acquisition of UV Mutations in the Skin

Peter Van Galen, Gabriel K. Griffin, Christopher A.G. Booth, Katsuhiro Togami, Sun Sook Chung, Daniel Ssozi, Julia A. Verga, Juliette M.C. Bouyssou, Yoke Seng Lee, Vignesh Shanmugam, Nicole R. LeBoeuf, Elizabeth A. Morgan, Bradley E. Bernstein, Volker Hovestadt, Andrew A. Lane

Blood (2022) 140 (Supplement 1): 1998–1999.

https://doi.org/10.1182/blood-2022-163666

Published: 2022

Journal Articles

BPDCN MYB Fusions Bind Cell Cycle Gene Promoters, Reactivate Self-Renewal in Progenitor Cells and Induce Myeloid/Dendritic Leukemia

Christopher A.G. Booth, Juliette M.C. Bouyssou, Katsuhiro Togami, Andrew A. Lane

Blood (2022) 140 (Supplement 1): 2000–2001.

https://doi.org/10.1182/blood-2022-159150

Published: 2022

Journal Articles

Male-Biased Spliceosome Mutations in Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Impair pDC Activation and Apoptosis

Blood (2020) 136 (Supplement 1): 13–14.

https://doi.org/10.1182/blood-2020-137727

Published: 2020

Journal Articles

Developmental Ontogeny of Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Revealed By Recurrent High Burden Clonal Hematopoiesis, Including in "Skin-Only" Disease

Gabriel K Griffin, MD, Katsuhiro Togami, MD PhD, Elizabeth A Morgan, MD, Andrew A. Lane, MD PhD

Blood (2018) 132 (Supplement 1): 2755.

https://doi.org/10.1182/blood-2018-99-119945

Published: 2018

Journal Articles

Nucleosome Binding Protein HMGN1 Promotes HSPC Competitive Advantage with Decreased Quiescence and Cooperates with AML Oncogenes to Block Differentiation and Increase Clonogenicity

Lucia Cabal-Hierro, PhD, Katsuhiro Togami, MD PhD, Kelly Higby, Andrew A. Lane, MD PhD

Blood (2018) 132 (Supplement 1): 2606.

https://doi.org/10.1182/blood-2018-99-119348

Published: 2018

Journal Articles

Resistance to SL-401 in AML and BPDCN Is Associated with Loss of the Diphthamide Synthesis Pathway Enzyme DPH1 and Is Reversible By Azacitidine

Jason Stephansky, Katsuhiro Togami, MDPhD, Mahmoud Ghandi, PhD, Joan Montero, PhD, Nick vonEgypt, Ross Lindsay, PhD, Christopher Brooks, PhD, Jon C. Aster, MD PhD, Cory Johannessen, PhD, Andrew A. Lane, MD PhD

Blood (2017) 130 (Supplement 1): 797.

https://doi.org/10.1182/blood.V130.Suppl_1.797.797

Published: 2017

Journal Articles

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Harbors Frequent Splicesosome Mutations That Cause Aberrant RNA Splicing Affecting Genes Critical in pDC Differentiation and Function

Blood (2016) 128 (22): 738.

https://doi.org/10.1182/blood.V128.22.738.738

Published: 2016

Journal Articles

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Is Highly BCL-2 Dependent and Sensitive to Venetoclax

Joan Montero, PhD, Jason Stephansky, BS, Tianyu Cai, PhD, Gabriel K. Griffin, MD, Katsuhiro Togami, MD PhD, Lucia Cabal-Hierro, PhD, Nicole R. LeBoeuf, MD, Leah Hogdal, PhD, Ilene Galinsky, MSN, ANPc, Jon C. Aster, MD PhD, Matthew S. Davids, Naveen Pemmaraju, MD, Richard M. Stone, MD, Marina Konopleva, MD PhD, Anthony Letai, MD PhD, Andrew A. Lane, MD PhD

Blood (2016) 128 (22): 4045.

https://doi.org/10.1182/blood.V128.22.4045.4045

Published: 2016

Journal Articles

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Patient-Derived Xenografts Are Faithful Genomic and Phenotypic Models of Primary Leukemia and Respond to the IL3 Receptor Targeting Agent SL-401 In Vivo

Amanda L Christie, B.S., Yvonne Li, PhD, Katsuhiro Togami, MD, Mahmoud Ghandi, PhD, Alexandra N. Christodoulou, M.S., Kevin Buczkowski, Fanny Angelot-Delettre, PhD, Sabeha Biichle, Janice Chen, PhD, Christopher L. Brooks, PhD, David M. Weinstock, MD, Francine Garnache-Ottou, PhD, Peter S Hammerman, MD PhD, Andrew A Lane, MD PhD

Blood (2015) 126 (23): 3797.

https://doi.org/10.1182/blood.V126.23.3797.3797

Published: 2015

Journal Articles

SETBP1 Mutations Drive Leukemic Transformation in ASXL1 -Mutated MDS

Daichi Inoue, MD PhD, Hirotaka Matsui, MD PhD, Hsin-An Hou, MD PhD, Wen-Chien Chou, MD PhD, Akiko Nagamachi, PhD, Jiro Kitaura, MD PhD, Kimihito Cojin Kawabata, MD PhD, Katsuhiro Togami, MD PhD, Reina Nagase, Sayuri Horikawa, Makoto Saika, MD, Jean-Baptiste Micol, MD, Yasutaka Hayashi, MD, Yuka Harada, MD PhD, Hironori Harada, MD PhD, Hwei-Fang Tien, MD PhD, Omar Abdel-Wahab, MD, Toshio Kitamura, MD PhD

Blood (2014) 124 (21): 525.

https://doi.org/10.1182/blood.V124.21.525.525

Published: 2014

Journal Articles

Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells

Blood (2014) 123 (25): 3932–3942.

https://doi.org/10.1182/blood-2013-01-476747

Published: 2014

Includes: Supplemental data

Journal Articles

C-Terminal-Truncating ASXL1 Mutations Induce MDS Via Inhibition Of PRC2

Daichi Inoue, MD, Jiro Kitaura, Katsuhiro Togami, Koutarou Nishimura, Yutaka Enomoto, Tomoyuki Uchida, Yuki Kagiyama, PhD, Kimihito Cojin Kawabata, Fumio Nakahara, Toshihiko Oki, Hironori Harada, Takahiro Ochiya, PhD, Hiroyuki Aburatani, M.D., Ph.D., Hiroshi Kimura, Felicitas Thol, MD, Michael Heuser, MD, Ross L. Levine, MD, Omar Abdel-Wahab, MD, Toshio Kitamura, MD, PhD

Blood (2013) 122 (21): 471.

https://doi.org/10.1182/blood.V122.21.471.471

Published: 2013

Journal Articles

Two types of C/EBPα mutations play distinct but collaborative roles in leukemogenesis: lessons from clinical data and BMT models

Naoko Kato, Jiro Kitaura, Noriko Doki, Yukiko Komeno, Naoko Watanabe-Okochi, Katsuhiro Togami, Fumio Nakahara, Toshihiko Oki, Yutaka Enomoto, Yumi Fukuchi, Hideaki Nakajima, Yuka Harada, Hironori Harada, Toshio Kitamura

Blood (2011) 117 (1): 221–233.

https://doi.org/10.1182/blood-2010-02-270181

Published: 2011

Includes: Supplemental data

Journal Articles

Feasibility of Reduced-Intensity Cord Blood Transplantation (RICBT) as a Salvage Therapy for Graft Failure (GF): Results of a Nationwide Survey of 63 Patients.

Blood (2006) 108 (11): 3114.

https://doi.org/10.1182/blood.V108.11.3114.3114

Published: 2006

NARROW

Clonal Hematopoiesis Evolves into Dendritic Cell Neoplasm through the Acquisition of UV Mutations in the Skin

BPDCN MYB Fusions Bind Cell Cycle Gene Promoters, Reactivate Self-Renewal in Progenitor Cells and Induce Myeloid/Dendritic Leukemia

Male-Biased Spliceosome Mutations in Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Impair pDC Activation and Apoptosis

Developmental Ontogeny of Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Revealed By Recurrent High Burden Clonal Hematopoiesis, Including in "Skin-Only" Disease

Nucleosome Binding Protein HMGN1 Promotes HSPC Competitive Advantage with Decreased Quiescence and Cooperates with AML Oncogenes to Block Differentiation and Increase Clonogenicity

Resistance to SL-401 in AML and BPDCN Is Associated with Loss of the Diphthamide Synthesis Pathway Enzyme DPH1 and Is Reversible By Azacitidine

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Harbors Frequent Splicesosome Mutations That Cause Aberrant RNA Splicing Affecting Genes Critical in pDC Differentiation and Function

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Is Highly BCL-2 Dependent and Sensitive to Venetoclax

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Patient-Derived Xenografts Are Faithful Genomic and Phenotypic Models of Primary Leukemia and Respond to the IL3 Receptor Targeting Agent SL-401 In Vivo

SETBP1 Mutations Drive Leukemic Transformation in ASXL1 -Mutated MDS

Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells

C-Terminal-Truncating ASXL1 Mutations Induce MDS Via Inhibition Of PRC2

Two types of C/EBPα mutations play distinct but collaborative roles in leukemogenesis: lessons from clinical data and BMT models

Feasibility of Reduced-Intensity Cord Blood Transplantation (RICBT) as a Salvage Therapy for Graft Failure (GF): Results of a Nationwide Survey of 63 Patients.

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American Society of Hematology

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American Society of Hematology

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