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Gabriel K. Griffin
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Journal Articles

Mutation-Specific Differences in the Relationship between Obesity and Clonal Hematopoiesis, with a Focus on JAK2 V617F and MPN Prevention

Benjamin Rolles, Aswin Sekar, Laura Serrano-Ron, Noorul Mifra Ameerul Faiz, Andrea Perry, Addison Clare Hillerbrandt, Jessica Hem, Jonas Jutzi, Anna E. Marneth, Abhishek Niroula, Alexander G. Bick, Christopher J. Gibson, Gabriel K. Griffin, Md Mesbah Uddin, Pradeep Natarajan, Benjamin Levine Ebert, Peter van Galen, Fatima Al-Shahrour, Sahand Hormoz, Ann Mullally
Journal: Blood
Blood (2024) 144 (Supplement 1): 872.
https://doi.org/10.1182/blood-2024-204211
Published: 2024
Journal Articles

Rapid Epigenomic Classification of Acute Leukemia

Til L. Steinicke, Salvatore Benfatto, Maria de los Reyes Capilla Guerra, Andre B. Monteleone, Subha Shankar, Phillip Michaels, Christoph Schliemann, Evan C. Chen, Gabriel K. Griffin, Volker Hovestadt
Journal: Blood
Blood (2024) 144 (Supplement 1): 273.
https://doi.org/10.1182/blood-2024-200868
Published: 2024
Journal Articles

A Novel BCR::ABL1 Rearrangement Harboring the Gatekeeper Mutation Drives Hyper-Kinase Activity Conferring Resistance to Ponatinib and Asciminib Combination Therapy

Valentina Nardi, Joshua Schwieterman, Zachary Kincaid, Andrew M. Brunner, Maria Reyes, Gabriel K. Griffin, Sekhu Ansari, Mohammad Azam
Journal: Blood
Blood (2024) 144 (Supplement 1): 4541.
https://doi.org/10.1182/blood-2024-211279
Published: 2024
Journal Articles

Post-Transplant T Cell Clonotype Diversity Is Associated with Survival in Patients with TP53-Mutated Acute Myeloid Leukemia

Nurefsan Sariipek, Kseniia R. Safina, Corey Cutler, Vincent T. Ho, John Koreth, Coleman Lindsley, Marlise R. Luskin, Jacqueline S. Garcia, Doreen Hearsey, Wesley S Lu, Shuqiang Li, Kenneth J. Livak, Gabriel K. Griffin, Robert J. Soiffer, Jerome Ritz, Catherine J Wu, Joseph H. Antin, Andrew A. Lane, Peter Van Galen, Mahasweta Gooptu
Journal: Blood
Blood (2023) 142 (Supplement 1): 2176.
https://doi.org/10.1182/blood-2023-181863
Published: 2023
Journal Articles

DNMT3A -Mutated Stem and Progenitor Cells Contribute to Altered T Cell Activation in Clonal Hematopoiesis

Ksenia R. Safina, Shawn David, Kyle A. Romine, Kristina D. Mujica, Daniel Ssozi, Jonathan Good, Nurefsan Sariipek, Yoke Seng Lee, Adrienne Parsons, Sarah Bibeau, Adam S. Sperling, Christopher James Gibson, Gabriel K. Griffin, Alexander G. Bick, Antonia Kreso, Jennifer J. Trowbridge, Peter van Galen
Journal: Blood
Blood (2023) 142 (Supplement 1): 1320.
https://doi.org/10.1182/blood-2023-180180
Published: 2023
Journal Articles

Clonal Hematopoiesis and Venous Thromboembolism in the UK Biobank

Becky Zon, Aswin Sekar, Katharine Clapham, Abhishek Niroula, Alexander G. Bick, Christopher James Gibson, Gabriel K. Griffin, Md Mesbah Uddin, Pradeep Natarajan, Benjamin L. Ebert
Journal: Blood
Blood (2023) 142 (Supplement 1): 568.
https://doi.org/10.1182/blood-2023-180764
Published: 2023
Journal Articles

Sensitivity to Targeted UBA1 Inhibition in a Myeloid Cell Line Model of Vexas Syndrome

Adriana Chiaramida, Sandra G. Obwar, Gabriel K. Griffin, Anja E.H. Nordstrom, Maria Ericsson, Dilshad H. Khan, Roger Belizaire
Journal: Blood
Blood (2023) 142 (Supplement 1): 939.
https://doi.org/10.1182/blood-2023-179447
Published: 2023
Journal Articles

Prediction of Risk for Myeloid Malignancy in Clonal Hematopoiesis

Lachelle D. Weeks, Abhishek Niroula, Donna S. Neuberg, Waihay J. Wong, R. Coleman Lindsley, Marlise R. Luskin, Nancy Berliner, Richard M. Stone, Daniel J DeAngelo, Robert J Soiffer, Md Mesbah Uddin, Christopher J. Gibson, Alexander G. Bick, Gabriel K. Griffin, Siddhartha Jaiswal, Luca Malcovati, Pradeep Natarajan, Benjamin L. Ebert
Journal: Blood
Blood (2022) 140 (Supplement 1): 2229–2231.
https://doi.org/10.1182/blood-2022-158960
Published: 2022
Journal Articles

Clonal Hematopoiesis Evolves into Dendritic Cell Neoplasm through the Acquisition of UV Mutations in the Skin

Peter Van Galen, Gabriel K. Griffin, Christopher A.G. Booth, Katsuhiro Togami, Sun Sook Chung, Daniel Ssozi, Julia A. Verga, Juliette M.C. Bouyssou, Yoke Seng Lee, Vignesh Shanmugam, Nicole R. LeBoeuf, Elizabeth A. Morgan, Bradley E. Bernstein, Volker Hovestadt, Andrew A. Lane
Journal: Blood
Blood (2022) 140 (Supplement 1): 1998–1999.
https://doi.org/10.1182/blood-2022-163666
Published: 2022
Journal Articles

TET2 -mutant clonal hematopoiesis and risk of gout

Clinical Trials & Observations
Mridul Agrawal, Abhishek Niroula, Pierre Cunin, Marie McConkey, Veronica Shkolnik, Peter G. Kim, Waihay J. Wong, Lachelle D. Weeks, Amy E. Lin, Peter G. Miller, Christopher J. Gibson, Aswin Sekar, Inga-Marie Schaefer, Donna Neuberg, Richard M. Stone, Alexander G. Bick, Md Mesbah Uddin, Gabriel K. Griffin, Siddhartha Jaiswal, Pradeep Natarajan, Peter A. Nigrovic, Deepak A. Rao, Benjamin L. Ebert
Journal: Blood
Blood (2022) 140 (10): 1094–1103.
https://doi.org/10.1182/blood.2022015384
Published: 2022
Includes: Supplemental data
Journal Articles

Obesity-Induced Inflammation Co-Operates with Clonal Hematopoiesis of Indeterminate Potential (CHIP) Mutants to Promote Leukemia Development and Cardiovascular Disease

Santhosh Kumar Pasupuleti, Baskar Ramdas, Sarah S. Burns, Ramesh Kumar, Taruni Reddy Pandhiri, George Sandusky, Zhi Yu, Michael Honigberg, Alexander G. Bick, Gabriel K. Griffin, Abhishek Niroula, Benjamin L. Ebert, Pradeep Natarajan, Reuben Kapur
Journal: Blood
Blood (2021) 138 (Supplement 1): 1094.
https://doi.org/10.1182/blood-2021-153521
Published: 2021
Journal Articles

Spatial signatures identify immune escape via PD-1 as a defining feature of T-cell/histiocyte-rich large B-cell lymphoma

Gabriel K. Griffin, Jason L. Weirather, Margaretha G. M. Roemer, Mikel Lipschitz, Alyssa Kelley, Pei-Hsuan Chen, Daniel Gusenleitner, Erin Jeter, Christine Pak, Evisa Gjini, Bjoern Chapuy, Michael H. Rosenthal, Jie Xu, Benjamin J. Chen, Aliyah R. Sohani, Scott B. Lovitch, Jeremy S. Abramson, Jeffrey J. Ishizuka, Austin I. Kim, Caron A. Jacobson, Ann S. LaCasce, Christopher D. Fletcher, Donna Neuberg, Gordon J. Freeman, F. Stephen Hodi, Kyle Wright, Azra H. Ligon, Eric D. Jacobsen, Philippe Armand, Margaret A. Shipp, Scott J. Rodig
Journal: Blood
Blood (2021) 137 (10): 1353–1364.
https://doi.org/10.1182/blood.2020006464
Published: 2021
Includes: Supplemental data
Journal Articles

Male-Biased Spliceosome Mutations in Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Impair pDC Activation and Apoptosis

Katsuhiro Togami, MDPhD, Sun Sook Chung, PhD, Vikas Madan, PhD, Christopher M. Kenyon, BS, Lucia Cabal-Hierro, PhD, Justin Taylor, MD, Sunhee Kim, MD, Gabriel K Griffin, MD, Mahmoud Ghandi, Jia Li, PhD, Yvonne Y. Li, PhD, Fanny Angelot-Delletre, PhD, Sabeha Biichle, Michael Seiler, Silvia Buonamici, PhD, Scott B Lovitch, MDPhD, Abner Louissaint, Jr., MD PhD, Elizabeth A Morgan, MD, Fabrice Jardin, MD PhD, Pier Paolo Piccaluga, MD PhD, David M. Weinstock, MD, Peter S. Hammerman, MD PhD, Henry Yang, PhD, Marina Konopleva, MD PhD, Naveen Pemmaraju, MD, Francine Garnache-Ottou, PhD, Omar Abdel-Wahab, MD, H. Phillip Koeffler, MD, Andrew A Lane, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-137727
Published: 2020
Journal Articles

Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade

Bjoern Chapuy, Chip Stewart, Andrew J. Dunford, Jaegil Kim, Kirsty Wienand, Atanas Kamburov, Gabriel K. Griffin, Pei-Hsuan Chen, Ana Lako, Robert A. Redd, Claire M. Cote, Matthew D. Ducar, Aaron R. Thorner, Scott J. Rodig, Gad Getz, Margaret A. Shipp
Journal: Blood
Blood (2019) 134 (26): 2369–2382.
https://doi.org/10.1182/blood.2019002067
Published: 2019
Includes: Supplemental data
Journal Articles

The microenvironmental niche in classic Hodgkin lymphoma is enriched for CTLA-4–positive T cells that are PD-1–negative

Sanjay S. Patel, Jason L. Weirather, Mikel Lipschitz, Ana Lako, Pei-Hsuan Chen, Gabriel K. Griffin, Philippe Armand, Margaret A. Shipp, Scott J. Rodig
Journal: Blood
Blood (2019) 134 (23): 2059–2069.
https://doi.org/10.1182/blood.2019002206
Published: 2019
Includes: Supplemental data
Journal Articles

Comparative Genomic Analyses Defines Shared and Unique Features of cHL and PMBL and New Mechanisms of Sensitivity to PD-1 Blockade

Kirsty Wienand, PhD, Bjoern Chapuy, MD PhD, Chip Stewart, PhD, Andrew Dunford, MS, David Wu, MD PhD, Jaegil Kim, PhD, Atanas Kamburov, PhD, Timothy Wood, Fathima Zumla Cader, MD PhD MRCP, Matthew D. Ducar, MS, Aaron R. Thorner, PhD, Anwesha Nag, PhD, Gabriel K Griffin, MD, Pei-Hsuan Chen, Alexander T Heubeck, BS, Michael J Buonopane, BS, Kamil Bojarczuk, PhD, Claire McEwen Cote, Lee N. Lawton, PhD, Philippe Armand, MD PhD, Scott J Rodig, MD PhD, Jonathan R. Fromm, MD PhD, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1493.
https://doi.org/10.1182/blood-2019-131904
Published: 2019
Journal Articles

Developmental Ontogeny of Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Revealed By Recurrent High Burden Clonal Hematopoiesis, Including in "Skin-Only" Disease

Gabriel K Griffin, MD, Katsuhiro Togami, MD PhD, Elizabeth A Morgan, MD, Andrew A. Lane, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2755.
https://doi.org/10.1182/blood-2018-99-119945
Published: 2018
Journal Articles

Integrated Genetic and Topological Analysis Reveals a Hodgkin-like Mechanism of Immune Escape in T-Cell/Histiocyte-Rich Large B-Cell Lymphoma

Gabriel K Griffin, MD, Margaretha G.M. Roemer, PhD, Mikel Lipschitz, M.S., Jason Weirather, PhD, Christine J. Pak, Allysa Kelly, Daniel Gusenleitner, PhD, Evisa Gjini, PhD, Bjoern Chapuy, MDPhD, Jie Xu, MD PhD, Benjamin Chen, MD PhD, Aliyah R. Sohani, MD, Scott B Lovitch, MD, PhD, Christopher Fletcher, MD, Gordon J Freeman, PhD, Stephen Hodi, Philippe Armand, MD PhD, Azra H. Ligon, PhD, Margaret A. Shipp, MD, Scott J Rodig, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1579.
https://doi.org/10.1182/blood-2018-99-118610
Published: 2018
Journal Articles

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Is Highly BCL-2 Dependent and Sensitive to Venetoclax

Joan Montero, PhD, Jason Stephansky, BS, Tianyu Cai, PhD, Gabriel K. Griffin, MD, Katsuhiro Togami, MD PhD, Lucia Cabal-Hierro, PhD, Nicole R. LeBoeuf, MD, Leah Hogdal, PhD, Ilene Galinsky, MSN, ANPc, Jon C. Aster, MD PhD, Matthew S. Davids, Naveen Pemmaraju, MD, Richard M. Stone, MD, Marina Konopleva, MD PhD, Anthony Letai, MD PhD, Andrew A. Lane, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4045.
https://doi.org/10.1182/blood.V128.22.4045.4045
Published: 2016
Journal Articles

Double-Hit and Double-Expressor Lymphomas Are Not Associated with an Adverse Outcome after Allogeneic Stem Cell Transplantation

Alex F Herrera, MD, Joo Y. Song, MD, Gabriel K. Griffin, MD, Liana Nikolaenko, MD, Matthew Mei, MD, Victoria Bedell, Paola Dal Cin, Christine Pak, Tracey Stiller, Heather Sun, Edwin P. Alyea, MD, Lihua E Budde, MD PhD, Robert W Chen, MD, Yi-Bin Chen, MD, Wing Chung Chan, MD, Corey S. Cutler, MD MPH, Vincent T. Ho, MD, John Koreth, MD, Amrita Krishnan, Joyce L. Murata-Collins, PhD, Sarah Nikiforow, MD PhD, Joycelynne M. Palmer, PhD, German A. Pihan, MD, Raju Pillai, MD, Leslie Popplewell, MD, Steven T. Rosen, MD, Tanya Siddiqi, MD, Aliyah R Sohani, MD, Jasmine Zain, MD, Larry W. Kwak, MD, Dennis D Weisenburger, MD, Auayporn P. Nademanee, MD, David M. Weinstock, MD, Robert J. Soiffer, MD, Joseph H. Antin, MD, Young Kim, MD, Scott J Rodig, Stephen J. Forman, MD, Philippe Armand, MD PhD
Journal: Blood
Blood (2016) 128 (22): 830.
https://doi.org/10.1182/blood.V128.22.830.830
Published: 2016