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Journal Articles

Spatial signatures identify immune escape via PD-1 as a defining feature of T-cell/histiocyte-rich large B-cell lymphoma

Gabriel K. Griffin, Jason L. Weirather, Margaretha G. M. Roemer, Mikel Lipschitz, Alyssa Kelley, Pei-Hsuan Chen, Daniel Gusenleitner, Erin Jeter, Christine Pak, Evisa Gjini, Bjoern Chapuy, Michael H. Rosenthal, Jie Xu, Benjamin J. Chen, Aliyah R. Sohani, Scott B. Lovitch, Jeremy S. Abramson, Jeffrey J. Ishizuka, Austin I. Kim, Caron A. Jacobson, Ann S. LaCasce, Christopher D. Fletcher, Donna Neuberg, Gordon J. Freeman, F. Stephen Hodi, Kyle Wright, Azra H. Ligon, Eric D. Jacobsen, Philippe Armand, Margaret A. Shipp, Scott J. Rodig
Journal: Blood
Blood (2021) 137 (10): 1353–1364.
https://doi.org/10.1182/blood.2020006464
Published: 2021
Includes: Supplemental data
Journal Articles

Pembrolizumab in Patients with Relapsed or Refractory Primary Mediastinal Large B-Cell Lymphoma (PMBCL): Data from the Keynote-013 and Keynote-170 Studies

Philippe Armand, MD PhD, Scott J Rodig, MDPhD, Vladimir Melnichenko, Catherine Thieblemont, MD, Krimo Bouabdallah, MD, Gayane Tumyan, DMSc, MD PhD, Muhit Özcan, Sergio Portino, MD, Laura Fogliatto, Dolores Caballero, MD, Jan Walewski, Zafer Gulbas, MD, Vincent Ribrag, MD, Beth A. Christian, MD, Guilherme Fleury Perini, Gilles Andre Salles, Jakub Svoboda, MD, Jasmine M. Zain, MD, Sanjay S Patel, MD MSc, MPH, Pei-Hsuan Chen, Azra H. Ligon, PhD, Jing Ouyang, Donna S Neuberg, ScD, Robert A. Redd, MS, Arkendu Chatterjee, Robert J Orlowski, MD, Arun Balakumaran, MD PhD SM, Margaret A. Shipp, MD, Pier Luigi Zinzani, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 228.
https://doi.org/10.1182/blood-2018-99-110220
Published: 2018
Journal Articles

Integrated Genetic and Topological Analysis Reveals a Hodgkin-like Mechanism of Immune Escape in T-Cell/Histiocyte-Rich Large B-Cell Lymphoma

Gabriel K Griffin, MD, Margaretha G.M. Roemer, PhD, Mikel Lipschitz, M.S., Jason Weirather, PhD, Christine J. Pak, Allysa Kelly, Daniel Gusenleitner, PhD, Evisa Gjini, PhD, Bjoern Chapuy, MDPhD, Jie Xu, MD PhD, Benjamin Chen, MD PhD, Aliyah R. Sohani, MD, Scott B Lovitch, MD, PhD, Christopher Fletcher, MD, Gordon J Freeman, PhD, Stephen Hodi, Philippe Armand, MD PhD, Azra H. Ligon, PhD, Margaret A. Shipp, MD, Scott J Rodig, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1579.
https://doi.org/10.1182/blood-2018-99-118610
Published: 2018
Journal Articles

Expression of Major Histocompatibility Complex (MHC) Class II, but Not MHC Class I, Predicts Outcome in Patients with Classical Hodgkin Lymphoma (cHL) Treated with Nivolumab (Programmed Death-1 [PD-1] Blockade)

Margaretha G.M. Roemer, MSc, Robert A. Redd, MS, Fathima Zumla Cader, MD PhD MRCP, Christine J. Pak, Sara Abdelrahman, Jing Ouyang, Stephanie Sasse, MD, Anas Younes, MD, Michelle A. Fanale, MD, Armando Santoro, MD, Pier Luigi Zinzani, MD, John M Timmerman, MD, Graham Collins, MD PhD, Rod Ramchandren, MD, Jonathon B Cohen, MDMS, Jan Paul De Boer, MD PhD, John Kuruvilla, MD, Kerry J Savage, BSc, MD MSc, Marek Trneny, MD, Stephen M Ansell, MD PhD, Mariana Sacchi, Benedetto Farsaci, MD, Anne Sumbul, Philippe Armand, MD PhD, Donna S. Neuberg, ScD, Geraldine S. Pinkus, Azra H. Ligon, Scott J. Rodig, MDPhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1450.
https://doi.org/10.1182/blood.V130.Suppl_1.1450.1450
Published: 2017
Journal Articles

Chromosome 9p24.1/ PD-L1 / PD-L2 Alterations and PD-L1 Expression and Treatment Outcomes in Patients with Classical Hodgkin Lymphoma Treated with Nivolumab (PD-1 Blockade)

Margaretha G M Roemer, Azra H. Ligon, PhD, Andreas Engert, MD, Anas Younes, MD, Armando Santoro, Pier Luigi Zinzani, MD PhD, John M. Timmerman, MD, Stephen Ansell, MD PhD, Philippe Armand, MD PhD, Michelle A Fanale, MD, Voravit Ratanatharathorn, MD, John Kuruvilla, MD, Jonathon B. Cohen, MD, Graham P. Collins, MD PhD, Kerry J Savage, MD, Marek Trneny, Donna S. Neuberg, ScD, Robert A Redd, MS, Benedetto Farsaci, Kazunobu Kato, MD, Anne Sumbul, Scott J Rodig, Margaret A. Shipp, MD
Journal: Blood
Blood (2016) 128 (22): 2923.
https://doi.org/10.1182/blood.V128.22.2923.2923
Published: 2016
Journal Articles

Targetable genetic features of primary testicular and primary central nervous system lymphomas

Bjoern Chapuy, Margaretha G. M. Roemer, Chip Stewart, Yuxiang Tan, Ryan P. Abo, Liye Zhang, Andrew J. Dunford, David M. Meredith, Aaron R. Thorner, Ekaterina S. Jordanova, Gang Liu, Friedrich Feuerhake, Matthew D. Ducar, Gerald Illerhaus, Daniel Gusenleitner, Erica A. Linden, Heather H. Sun, Heather Homer, Miyuki Aono, Geraldine S. Pinkus, Azra H. Ligon, Keith L. Ligon, Judith A. Ferry, Gordon J. Freeman, Paul van Hummelen, Todd R. Golub, Gad Getz, Scott J. Rodig, Daphne de Jong, Stefano Monti, Margaret A. Shipp
Journal: Blood
Blood (2016) 127 (7): 869–881.
https://doi.org/10.1182/blood-2015-10-673236
Published: 2016
Includes: Supplemental data
Journal Articles

PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome

Margaretha GM Roemer, MS, Ranjana H Advani, MD, Azra H. Ligon, PhD, Yasodha Natkunam, MD PhD, Robert A Redd, MS, Heather Homer, Courtney Connelly, Heather H. Sun, Sarah E. Daadi, Bjoern Chapuy, MD PhD, Daphne de Jong, MD PhD, Richard T. Hoppe, MD, Donna S Neuberg, ScD, Scott J Rodig, MD PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2015) 126 (23): 176.
https://doi.org/10.1182/blood.V126.23.176.176
Published: 2015
Journal Articles

Nivolumab in Patients with Relapsed or Refractory Hodgkin Lymphoma - Preliminary Safety, Efficacy and Biomarker Results of a Phase I Study

Philippe Armand, MD PhD, Stephen M. Ansell, MD PhD, Alexander M. Lesokhin, MD, Ahmad Halwani, MD, Michael M. Millenson, MD, Stephen J. Schuster, MD, John Timmerman, MD, Ivan Borrello, MD, Martin Gutierrez, MD, Emma C. Scott, MD, Deepika Cattry, MSc, CCRP, Bjoern Chapuy, MD PhD, Azra H. Ligon, PhD, Scott J. Rodig, MD PhD, Lili Zhu, MSc, Joseph F. Grosso, PhD, Su Young Kim, MD PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2014) 124 (21): 289.
https://doi.org/10.1182/blood.V124.21.289.289
Published: 2014
Journal Articles

Preliminary Results of a Phase I Study of Nivolumab (BMS-936558) in Patients with Relapsed or Refractory Lymphoid Malignancies

Alexander M. Lesokhin, MD, Stephen M. Ansell, MD PhD, Philippe Armand, MD PhD, Emma C. Scott, MD, Ahmad Halwani, MD, Martin Gutierrez, MD, Michael M. Millenson, MD, Adam D. Cohen, MD, Stephen J. Schuster, MD, Daniel Lebovic, Madhav V. Dhodapkar, MD, David Avigan, MD, Bjoern Chapuy, MD PhD, Azra H. Ligon, PhD, Scott J. Rodig, MD PhD, Deepika Cattry, MSc, CCRP, Lili Zhu, MSc, Joseph F. Grosso, PhD, Su Young Kim, MD PhD, Margaret A. Shipp, MD, Ivan Borrello, MD, John Timmerman, MD
Journal: Blood
Blood (2014) 124 (21): 291.
https://doi.org/10.1182/blood.V124.21.291.291
Published: 2014
Journal Articles

Recurrent BRAF mutations in Langerhans cell histiocytosis

Brief Report
Gayane Badalian-Very, Jo-Anne Vergilio, Barbara A. Degar, Laura E. MacConaill, Barbara Brandner, Monica L. Calicchio, Frank C. Kuo, Azra H. Ligon, Kristen E. Stevenson, Sarah M. Kehoe, Levi A. Garraway, William C. Hahn, Matthew Meyerson, Mark D. Fleming, Barrett J. Rollins
Journal: Blood
Blood (2010) 116 (11): 1919–1923.
https://doi.org/10.1182/blood-2010-04-279083
Published: 2010
Includes: Supplemental data