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Jo-Anne Vergilio
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Journal Articles

Liquid Biopsy-Based Next-Generation Sequencing Is an Alternative to Tissue Molecular Profiling of Lymphoid, Plasma-Cell, and Myeloid Neoplasms

Douglas A Mata, Jessica K Lee, Brennan Decker, Vignesh Shanmugam, Chelsea B Marcus, Hanna Tukachinsky, Alexa B Schrock, Nimesh R Patel, Jeffrey S Ross, Geoffrey R Oxnard, Jo-Anne Vergilio, Kamran M Mirza, Mina L Xu, Jamal K Benhamida
Journal: Blood
Blood (2022) 140 (Supplement 1): 1205–1207.
https://doi.org/10.1182/blood-2022-159106
Published: 2022
Journal Articles

A Risk-Adapted Study to Assess the Efficacy of Enasidenib and Subsequent Response-Driven Addition of Azacitidine for Newly Diagnosed IDH2 -Mutant AML Patients: 3-Year Follow-up

Eytan Stein, Sheng F Cai, Ying Huang, Andrew Dunbar, Maria R. Baer, Wendy Stock, Tibor Kovacsovics, William G. Blum, Gary J. Schiller, Rebecca L. Olin, James M. Foran, Mark R. Litzow, Tara L. Lin, Prapti A. Patel, Matthew C. Foster, Michael M. Boyiadzis, Robert H. Collins, Jordan Chervin, Abigail B. Shoben, Jo-Anne Vergilio, Nyla A. Heerema, Leonard Rosenberg, Timothy Chen, Ashley O. Yocum, Franchesca Druggan, Sonja Marcus, Mona Stefanos, Molly Martycz, Brian J. Druker, Alice S. Mims, Uma Borate, Amy Burd, John C. Byrd, Ross L. Levine
Journal: Blood
Blood (2022) 140 (Supplement 1): 2016–2019.
https://doi.org/10.1182/blood-2022-166850
Published: 2022
Journal Articles

Ivosidenib (IVO) in Combination with Azacitidine (AZA) in Newly Diagnosed (ND) Older Patients with IDH1 R132-Mutated Acute Myeloid Leukemia (AML) Induces High Response Rates: A Phase 2 Sub-Study of the Beat AML Master Trial

Prapti Patel, Amy S. Ruppert, Uma Borate, Eytan M. Stein, Maria R. Baer, Wendy Stock, Tibor Kovacsovics, William Blum, Martha L. Arellano, Gary J. Schiller, Rebecca L. Olin, James M. Foran, Mark R. Litzow, Tara L. Lin, Matthew C. Foster, Robert L. Redner, Zeina Al-Mansour, Christopher R. Cogle, Michael M. Boyiadzis, Ronan Swords, Robert H. Collins, Jo-Anne Vergilio, Nyla A. Heerema, Leonard Rosenberg, Ashley Owen Yocum, Sonja Marcus, Timothy Chen, Franchesca Druggan, Mona Stefanos, Theophilus J Gana, Abigail B. Shoben, Brian J. Druker, Amy Burd, John C. Byrd, Ross L. Levine, Alice S. Mims
Journal: Blood
Blood (2021) 138 (Supplement 1): 875.
https://doi.org/10.1182/blood-2021-149115
Published: 2021
Journal Articles

CDKN2A Deletions Define an Unfavorable Subgroup within the MYD88/CD79B (MCD) Subtype of Diffuse Large B-Cell Lymphoma (DLBCL) and Are Mutually Exclusive with TP53 mutations

Adam J. Olszewski, Radwa Sharaf, Chelsea Marcus, Habibe Kurt, Lee A Albacker, Jo-Anne Vergilio, Thomas A. Ollila
Journal: Blood
Blood (2021) 138 (Supplement 1): 2392.
https://doi.org/10.1182/blood-2021-146335
Published: 2021
Journal Articles

Gilteritinib (GILT) Monotherapy with Addition of Decitabine (DEC) in Non-Responders in Older Newly Diagnosed (ND) FLT3 Mutated Acute Myeloid Leukemia (AML) Patients Having High and Low Variant Allele Frequency (VAF): A Phase 2/1b Sub-Study of the Beat AML Master Trial

Elie Traer, Ying Huang, Alice S. Mims, Eytan M. Stein, Maria R. Baer, Wendy Stock, Tibor Kovacsovics, William Blum, Martha L. Arellano, Gary J. Schiller, Rebecca L. Olin, James M. Foran, Mark R. Litzow, Tara L. Lin, Prapti Patel, Matthew C. Foster, Robert L. Redner, Zeina Al-Mansour, Christopher R. Cogle, Michael M. Boyiadzis, Ronan Swords, Robert H. Collins, Jo-Anne Vergilio, Nyla A. Heerema, Leonard Rosenberg, Ashley O. Yocum, Sonja Marcus, Timothy Chen, Franchesca Druggan, Mona Stefanos, Theophilus J Gana, Abigail B. Shoben, Brian J. Druker, Amy Burd, John C. Byrd, Ross L. Levine, Uma Borate
Journal: Blood
Blood (2021) 138 (Supplement 1): 1277.
https://doi.org/10.1182/blood-2021-148207
Published: 2021
Journal Articles

Entospletinib (ENTO) and Decitabine (DEC) Combination Therapy in Older Newly Diagnosed (ND) Acute Myeloid Leukemia (AML) Patients with Mutant TP53 or Complex Karyotype Is Associated with Poor Response and Survival: A Phase 2 Sub-Study of the Beat AML Master Trial

Vu H. Duong, Amy S. Ruppert, Alice S. Mims, Uma Borate, Eytan M. Stein, Maria R. Baer, Wendy Stock, Tibor Kovacsovics, William G. Blum, Martha L. Arellano, Gary J. Schiller, Rebecca L. Olin, James M. Foran, Mark R. Litzow, Tara L. Lin, Prapti A. Patel, Matthew C. Foster, Robert L. Redner, Zeina Al-Mansour, Christopher R. Cogle, Ronan T. Swords, Robert H. Collins, Jo-Anne Vergilio, Nyla A. Heerema, Leonard Rosenberg, Ashley O. Yocum, Sonja Marcus, Timothy Chen, Franchesca Druggan, Mona Stefanos, Theophilus J Gana, Abigail B. Shoben, Brian J. Druker, Amy Burd, John C. Byrd, Ross L. Levine, Michael M. Boyiadzis
Journal: Blood
Blood (2021) 138 (Supplement 1): 1279.
https://doi.org/10.1182/blood-2021-151234
Published: 2021
Journal Articles

Genomic Ancestry in B Cell Lymphoid Malignancies

Jay A Moore, Andrew M. Evens, DO,MMSc, Justin Newberg, PhD, Eric A. Severson, MD, PhD, MMSc, Jennifer Mills, PhD MSW, MPH, Jordan Carter, MD, Rahul Matnani, MD, Jo-Anne Vergilio, MD, Sally E Trabucco, PhD, Shridar Ganesan, MD, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-137533
Published: 2020
Journal Articles

Enasidenib (ENA) Monotherapy with Addition of Azacitidine in Non-Responders Is Effective in Older Patients with Newly Diagnosed IDH2 Mutated Acute Myeloid Leukemia (AML): A Completed Phase 2/1b Sub-Study of the Beat AML Master Trial

Eytan M. Stein, MD, Ying Huang, MS, MA, Uma Borate, Maria R. Baer, MD, Wendy Stock, MD, Tibor Kovacsovics, MD, William Blum, MD, Gary J. Schiller, MD, Rebecca L. Olin, MD, James M. Foran, MD, Mark Litzow, MD, Tara Lin, MD, Prapti A. Patel, MD, Matthew C Foster, MD, Michael Boyiadzis, MD, Robert H. Collins, MD, Jo-Anne Vergilio, MD, Nyla A Heerema, PhD, Leonard Rosenberg, Ashley Owen Yocum, PhD, Timothy Chen, PhD, Franchesca Druggan, MSc, Sonja Marcus, MPH, Mona Stefanos, MBChB, Jordan Chervin, Abigail Shoben, Brian J. Druker, MD, Amy Burd, PhD, John C. Byrd, MD, Ross L. Levine, MD, Alice S. Mims, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 27–30.
https://doi.org/10.1182/blood-2020-143265
Published: 2020
Journal Articles

Acid-Based Decalcification Methods Compromise Genomic Profiling from DNA and RNA

Ian Duncan, Natalie Danziger, Daniel Duncan, MD, Amanda Hemmerich, MD, Claire Edgerly, MD, Richard Huang, MD, Jo-Anne Vergilio, MD, Julia A Elvin, MD PhD, Jie He, PhD, Nicholas Britt, Prasanth Reddy, MD, Pratheesh Sathyan, MD, Brian Alexander, MD, Jeffrey S. Ross, MD, Charlotte Brown, PhD, Shakti H. Ramkissoon, MD PhD, Eric A. Severson, MD, PhD, MMSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 4659.
https://doi.org/10.1182/blood-2019-131362
Published: 2019
Journal Articles

Newly Diagnosed AML Patient Samples Demonstrate High Degree of Concordance in Identification of Pathogenic Mutations By Next Generation Sequencing (NGS) Performed at Enrolling Institutions Compared to Central Laboratory Results in the Beat AML Master Trial

Uma Borate, MD, Amy S. Ruppert, MAS, PhD, Fei Yang, MD, Dan Jones, MD PhD, Sean Caruthers, Weiqiang Zhao, MD PhD, Jo-Anne Vergilio, MD, Amy Burd, PhD, Dean Pavlick, Luke Juckett, BSc, BA, MSc, Eytan M. Stein, MD, Prapti A. Patel, MD, Maria R. Baer, MD, Wendy Stock, MD, Gary J. Schiller, MD, William Blum, MD, Tibor Kovacsovics, MD, Mark Litzow, MD, James M. Foran, MD, Nyla A. Heerema, PhD, Leonard Rosenberg, Sonja Marcus, MPH, Ashley Owen Yocum, PhD, Mona Stefanos, MBChB, Brian J. Druker, John C. Byrd, MD, Ross L. Levine, MD, Alice S. Mims, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2145.
https://doi.org/10.1182/blood-2019-131253
Published: 2019
Journal Articles

Loss of Heterozygosity of FLT3-ITD Is Common in Acute Myeloid Leukemia and May be a More Consistent Prognostic Marker Than FLT3-ITD Allele Frequency

Eric A. Severson, MD, PhD, MMSc, Ethan S. Sokol, PhD, Russell Madison, PhD, Daniel Duncan, MD, Amanda Hemmerich, MD, Claire Edgerly, MD, Richard Huang, MD, Nicholas Britt, Jo-Anne Vergilio, MD, Julia A Elvin, MD PhD, Prasanth Reddy, MD, Pratheesh Sathyan, MD, Brian Alexander, MD, Jeffrey S. Ross, MD, Siraj M Ali, MD PhD, Shakti H. Ramkissoon, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1437.
https://doi.org/10.1182/blood-2019-131248
Published: 2019
Journal Articles

Comprehensive Genomic Profiling of 104 Rare Histiocytic and Dendritic Cell Neoplasms Reveals Shared and Distinct Targetable Genomic Alterations

Lucas R. Massoth, MD, Yin P. Hung, MD, PhD, Judith A. Ferry, MD, Robert P. Hasserjian, MD, Abner Louissaint, Jr., MD PhD, Meagan Montesion, PhD, Ethan S. Sokol, PhD, Dean C. Pavlick, Nikunj Shah, Natalie Danziger, Jonathan Keith Killian, MD,PhD, Eric A. Severson, MD, PhD, MMSc, Daniel Duncan, MD, Julia A. Elvin, MD, PhD, Vincent A. Miller, MD, Jeffrey S. Ross, MD, Jo-Anne Vergilio, MD, Lawrence R. Zukerberg, MD, Erik A. Williams, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2541.
https://doi.org/10.1182/blood-2019-123729
Published: 2019
Journal Articles

Prevalence of Inherited Cancer Predisposition Mutations in a Cohort of Older AML Patients Enrolled on the Beat AML Master Trial

Uma Borate, MD, Fei Yang, MD, Richard D. Press, MD PhD, Dean Pavlick, Luke Juckett, BSc, BA, MSc, Anupriya Agarwal, PhD, Amy Burd, PhD, Alice S. Mims, MD, Eytan M. Stein, MD, Prapti A. Patel, MD, Maria R. Baer, MD, Wendy Stock, MD, Gary J. Schiller, MD, William Blum, MD, Paul J Shami, MD, Mark Litzow, MD, James M. Foran, MD, Nyla A. Heerema, PhD, Leonard Rosenberg, Sonja Marcus, MPH, Ashley Owen Yocum, PhD, Mona Stefanos, MBChB, John C. Byrd, MD, Brian J. Druker, Jo-Anne Vergilio, MD, Ross L. Levine, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 373.
https://doi.org/10.1182/blood-2019-131925
Published: 2019
Journal Articles

Precision Medicine Treatment in Older AML: Results of Beat AML Master Trial

Amy Burd, PhD, Ross L. Levine, MD, Amy S. Ruppert, MAS, PhD, Alice S. Mims, MD, Uma Borate, MD, Eytan M. Stein, MD, Prapti A. Patel, MD, Maria R. Baer, MD, Wendy Stock, MD, Michael W. Deininger, William Blum, MD, Gary J. Schiller, MD, Rebecca L. Olin, MD, Mark Litzow, MD, James M. Foran, MD, Tara L. Lin, MD, Brian J Ball, Michael Boyiadzis, MD, Elie Traer, Olatoyosi Odenike, MD, Martha L. Arellano, MD, Alison R. Walker, MD, Vu H. Duong, MD, Robert H. Collins, MD, Nyla A. Heerema, PhD, Jo-Anne Vergilio, MD, TIm Brennan, PhD, Christine Vietz, Molly Vittorio, Leonard Rosenberg, Sonja Marcus, MPH, Ashley Owen Yocum, PhD, Mona Stefanos, MBChB, Brian J. Druker, John C. Byrd, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 175.
https://doi.org/10.1182/blood-2019-130201
Published: 2019
Journal Articles

Phase 1b Dose Escalation Study of BI 836858 and Azacitidine in Previously Untreated AML: Results from Beat AML S2

William Blum, MD, Amy S. Ruppert, MAS, PhD, Alice S. Mims, MD, Eytan M. Stein, MD, Vu H Duong, MD, Olatoyosi Odenike, MD, Prapti A. Patel, MD, Tibor Kovacsovics, MD, Nyla A. Heerema, PhD, Jo-Anne Vergilio, MD, Leonard Rosenberg, Sonja Marcus, MPH, Mona Stefanos, MBChB, Howard Weiner, Jake Brandt, Abigail Shoben, Brian J. Druker, MD, Amy Burd, PhD, Ross L. Levine, MD, John C. Byrd, MD, Uma Borate, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4053.
https://doi.org/10.1182/blood-2018-99-116199
Published: 2018
Journal Articles

A Next-Generation Sequencing-Based Karyotyping Algorithm Reveals the Genomic Structure of Acute Myeloid Leukemia

Dean Pavlick, Meagan Montesion, PhD, Nyla A. Heerema, PhD, Eric A Severson, MD PhD MMSc, Timothy Brennan, Garrett M Frampton, Jie He, PhD, John C. Byrd, MD, Ross L. Levine, MD, Amy Burd, PhD, Jo-Anne Vergilio, MD, Lee A Albacker, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2773.
https://doi.org/10.1182/blood-2018-99-116195
Published: 2018
Journal Articles

Initial Report of the Beat AML Umbrella Study for Previously Untreated AML: Evidence of Feasibility and Early Success in Molecularly Driven Phase 1 and 2 Studies

Amy Burd, PhD, Ross L. Levine, MD, Abigail Shoben, Alice S. Mims, MD, Uma Borate, MD, Eytan M. Stein, MD, Prapti A. Patel, MD, Maria R. Baer, MD, Wendy Stock, MD, Michael W. Deininger, MD PhD, Amy S. Ruppert, MAS, PhD, Nyla A. Heerema, PhD, Jo-Anne Vergilio, MD, TIm Brennan, PhD, Christine Vietz, Molly Vittorio, Leonard Rosenberg, Sonja Marcus, MPH, Mona Stefanos, MBChB, Brian J. Druker, MD, John C. Byrd, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 559.
https://doi.org/10.1182/blood-2018-99-118494
Published: 2018
Journal Articles

Enasidenib Is Highly Active in Previously Untreated IDH2 Mutant AML: Early Results from the Beat AML Master Trial

Eytan M. Stein, MD, Abigail Shoben, Uma Borate, MD, Maria R. Baer, MD, Wendy Stock, MD, Prapti A. Patel, MD, Tibor Kovacsovics, MD, William Blum, MD, Jo-Anne Vergilio, MD, Nyla A. Heerema, PhD, Leonard Rosenberg, Sonja Marcus, MPH, Mona Stefanos, MBChB, Jordan Chervin, Brian J. Druker, MD, Amy Burd, PhD, John C. Byrd, MD, Ross L. Levine, MD, Alice S. Mims, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 287.
https://doi.org/10.1182/blood-2018-99-118287
Published: 2018
Journal Articles

Detection of clonal hematopoiesis of indeterminate potential in clinical sequencing of solid tumor specimens

Clinical Trials & Observations
Eric A. Severson, Gregory M. Riedlinger, Caitlin F. Connelly, Jo-Anne Vergilio, Mendel Goldfinger, Shakti Ramkissoon, Garrett M. Frampton, Jeffrey S. Ross, Anthony Fratella-Calabrese, Laurie Gay, Siraj Ali, Vincent Miller, Julia Elvin, Mohammad Hadigol, Kim M. Hirshfield, Lorna Rodriguez-Rodriguez, Shridar Ganesan, Hossein Khiabanian
Journal: Blood
Blood (2018) 131 (22): 2501–2505.
https://doi.org/10.1182/blood-2018-03-840629
Published: 2018
Includes: Supplemental data
Journal Articles

Comprehensive Genomic Profiling (CGP) Informs Molecular Diagnosis, Prognosis, and Therapeutic Decision-Making for Patients with Angioimmunoblastic T-Cell Lymphoma (AITL)

Samantha Morley, PhD, Jie He, PhD, Andrew M Intlekofer, MD PhD, Mark Bailey, MS, Michelle Nahas, PhD, Andreas Heilmann, PhD, Yakov Chudnovsky, PhD, David Fabrizio, PhD, Siraj M Ali, MD PhD, Doron Lipson, PhD, Philip J Stephens, PhD, Jeffrey S Ross, MD, Vincent A Miller, MD, Eric A Severson, MD PhD MMSc, Jo-Anne Vergilio, MD, Omar Abdel-Wahab, MD, Rachel Erlich, PhD, Tariq I Mughal, MD FRCP
Journal: Blood
Blood (2017) 130 (Supplement 1): 5134.
https://doi.org/10.1182/blood.V130.Suppl_1.5134.5134
Published: 2017