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Fumio Nakahara
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Journal Articles

Efficient production of human neutrophils from iPSCs that prevent murine lethal infection with immune cell recruitment

Masashi Miyauchi, Yusuke Ito, Fumio Nakahara, Toshiya Hino, Fumi Nakamura, Yuki Iwasaki, Taiki Kawagoshi, Junji Koya, Akihide Yoshimi, Shunya Arai, Yuki Kagoya, Mineo Kurokawa
Journal: Blood
Blood (2021) 138 (24): 2555–2569.
https://doi.org/10.1182/blood.2021011576
Published: 2021
Includes: Supplemental data
Journal Articles

CD62L Expression Level Dictates the Cell Fate of Myeloid Progenitors in Mice and Humans

Yusuke Ito, MD, Fumio Nakahara, MD PhD, Yuki Kagoya, MD PhD, Mineo Kurokawa, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–27.
https://doi.org/10.1182/blood-2020-134753
Published: 2020
Journal Articles

Predictors of Glucocorticoid Responsiveness in Multicentric Castleman's Disease

Kazutoshi Ebisawa, MD, Arika Nukina Shimura, MD, Akira Honda, MD PhD, Yosuke Masamoto, MD PhD, Fumio Nakahara, MD PhD, Mineo Kurokawa, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-136469
Published: 2020
Journal Articles

VCAM1 Confers Innate Immune Tolerance on Hematopoietic and Leukemic Stem Cells

Sandra Pinho, PhD, Qiaozhi Wei, PhD, Maria Maryanovich, PhD, Halley Pierce, PhD, Fumio Nakahara, MD PhD, Jianing Xu, PhD, Daniel K. Borger, MS, Dachuan Zhang, PhD, Amit Verma, MBBS, Paul S. Frenette, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 524.
https://doi.org/10.1182/blood-2019-123431
Published: 2019
Journal Articles

Engineering a Hematopoietic Stem Cell Niche By Revitalizing Mesenchymal Stem Cells with Five Transcription Factors

Fumio Nakahara, MD PhD, Sandra Pinho, PhD, Daniel K. Borger, MS, Qiaozhi Wei, PhD, Maria Maryanovich, PhD, Ali H. Zahalka, Masako Suzuki, Cristian Cruz, Zichen Wang, Chunliang Xu, PhD, Philip Boulais, PhD, Avi Ma'ayan, John M. Greally, MB, PhD, Paul S. Frenette, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5004.
https://doi.org/10.1182/blood-2019-125045
Published: 2019
Journal Articles

Genetically Engineered Hematopoietic Progenitors Derived from Human Induced Pluripotent Stem Cells Achieve the Feeder-Free and Robust Production of Neutrophils with the Functional Capacity In Vivo

Masashi Miyauchi, Yusuke ITO, MD, Fumio Nakahara, MD PhD, Fumi Nakamura, MD PhD, Yuki Iwasaki, Taiki Kawagoshi, Yuki Kagoya, MD PhD, Shunya Arai, MD PhD, Mineo Kurokawa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 720.
https://doi.org/10.1182/blood-2019-126348
Published: 2019
Journal Articles

Loss of Adrenergic Nerves in the Bone Marrow Microenvironment Drives an Aging HSC Niche Phenotype

Maria Maryanovich, PhD, Ali H. Zahalka, MSc, Halley Pierce, MSc, Sandra Pinho, PhD, Fumio Nakahara, MDPhD, Noboru Asada, MDPhD, Avigdor Leftin, PhD, Jan Vijg, PhD, Paul S. Frenette, MD
Journal: Blood
Blood (2016) 128 (22): 169.
https://doi.org/10.1182/blood.V128.22.169.169
Published: 2016
Journal Articles

Vcam1 Is a "Don't-Eat-Me" Signal on Healthy Hematopoietic and Leukemic Stem Cells

Sandra Pinho, PhD, Wei Qiaozhi, PhD, Maria Maryanovich, PhD, Halley Pierce, MSc, Fumio Nakahara, MD PhD, Paul S. Frenette, MD
Journal: Blood
Blood (2016) 128 (22): 565.
https://doi.org/10.1182/blood.V128.22.565.565
Published: 2016
Journal Articles

Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells

Fumio Nakahara, Jiro Kitaura, Tomoyuki Uchida, Chiemi Nishida, Katsuhiro Togami, Daichi Inoue, Toshihiro Matsukawa, Yuki Kagiyama, Yutaka Enomoto, Kimihito C. Kawabata, Lai Chen-Yi, Yukiko Komeno, Kumi Izawa, Toshihiko Oki, Genta Nagae, Yuka Harada, Hironori Harada, Makoto Otsu, Hiroyuki Aburatani, Beate Heissig, Koichi Hattori, Toshio Kitamura
Journal: Blood
Blood (2014) 123 (25): 3932–3942.
https://doi.org/10.1182/blood-2013-01-476747
Published: 2014
Includes: Supplemental data
Journal Articles

C-Terminal-Truncating ASXL1 Mutations Induce MDS Via Inhibition Of PRC2

Daichi Inoue, MD, Jiro Kitaura, Katsuhiro Togami, Koutarou Nishimura, Yutaka Enomoto, Tomoyuki Uchida, Yuki Kagiyama, PhD, Kimihito Cojin Kawabata, Fumio Nakahara, Toshihiko Oki, Hironori Harada, Takahiro Ochiya, PhD, Hiroyuki Aburatani, M.D., Ph.D., Hiroshi Kimura, Felicitas Thol, MD, Michael Heuser, MD, Ross L. Levine, MD, Omar Abdel-Wahab, MD, Toshio Kitamura, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 471.
https://doi.org/10.1182/blood.V122.21.471.471
Published: 2013
Journal Articles

Two types of C/EBPα mutations play distinct but collaborative roles in leukemogenesis: lessons from clinical data and BMT models

Naoko Kato, Jiro Kitaura, Noriko Doki, Yukiko Komeno, Naoko Watanabe-Okochi, Katsuhiro Togami, Fumio Nakahara, Toshihiko Oki, Yutaka Enomoto, Yumi Fukuchi, Hideaki Nakajima, Yuka Harada, Hironori Harada, Toshio Kitamura
Journal: Blood
Blood (2011) 117 (1): 221–233.
https://doi.org/10.1182/blood-2010-02-270181
Published: 2011
Includes: Supplemental data
Journal Articles

Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia

Fumio Nakahara, Mamiko Sakata-Yanagimoto, Yukiko Komeno, Naoko Kato, Tomoyuki Uchida, Kyoko Haraguchi, Keiki Kumano, Yuka Harada, Hironori Harada, Jiro Kitaura, Seishi Ogawa, Mineo Kurokawa, Toshio Kitamura, Shigeru Chiba
Journal: Blood
Blood (2010) 115 (14): 2872–2881.
https://doi.org/10.1182/blood-2009-05-222836
Published: 2010
Includes: Supplemental data
Journal Articles

Balance of Transcription Factors Downstream of Notch Signaling Determines the Fate of Myeloid Progenitors toward Differentiation to Mast Cells or Immortalization without Differentiation.

Mamiko Sakata-Yanagimoto, MD, Fumio Nakahara, MD, Etsuko Yamaguchi-Nakagami, MD, Keiki Kumano, MD, PhD, Toshiki Saito, MD, PhD, Mineo Kurokawa, MD, PhD, Seishi Ogawa, MD, PhD, Shigeru Chiba, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 676.
https://doi.org/10.1182/blood.V108.11.676.676
Published: 2006