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Joseph R. Biggs
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Journal Articles

Expression of the runt homology domain of RUNX1 disrupts homeostasis of hematopoietic stem cells and induces progression to myelodysplastic syndrome

Shinobu Matsuura, Yukiko Komeno, Kristen E. Stevenson, Joseph R. Biggs, Kentson Lam, Tingdong Tang, Miao-Chia Lo, Xiuli Cong, Ming Yan, Donna S. Neuberg, Dong-Er Zhang
Journal: Blood
Blood (2012) 120 (19): 4028–4037.
https://doi.org/10.1182/blood-2012-01-404533
Published: 2012
Includes: Supplemental data
Journal Articles

Acute myeloid leukemia with the 8q22;21q22 translocation: secondary mutational events and alternative t(8;21) transcripts

Luke F. Peterson, Anita Boyapati, Eun-Young Ahn, Joseph R. Biggs, Akiko Joo Okumura, Miao-Chia Lo, Ming Yan, Dong-Er Zhang
Journal: Blood
Blood (2007) 110 (3): 799–805.
https://doi.org/10.1182/blood-2006-11-019265
Published: 2007
Journal Articles

A leukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy

Anita Boyapati, Ming Yan, Luke F. Peterson, Joseph R. Biggs, Michelle M. Le Beau, Dong-Er Zhang
Journal: Blood
Blood (2006) 109 (9): 3963–3971.
https://doi.org/10.1182/blood-2006-09-045583
Published: 2006
Includes: Supplemental data
Journal Articles

Phosphorylation of AML1 (RUNX1) Controls Transcription, Nuclear Localization, and Is Regulated during DNA Damage.

Suiquan Wang, PhD, Youhong Zhang, PhD, Joseph R. Biggs, PhD, Dong-Er Zhang, PhD, Andrew S. Kraft, MD
Journal: Blood
Blood (2005) 106 (11): 2712.
https://doi.org/10.1182/blood.V106.11.2712.2712
Published: 2005
Journal Articles

Cyclin-Dependent Kinases Phosphorylate AML1 (RUNX1) and Regulate AML1 Transactivation.

Joseph R. Biggs, PhD, Luke F. Peterson, PhD, Youhong Zhang, PhD, Andrew S. Kraft, MD, Dong-Er Zhang, PhD
Journal: Blood
Blood (2005) 106 (11): 2721.
https://doi.org/10.1182/blood.V106.11.2721.2721
Published: 2005