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Steven J. Howe
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Journal Articles

Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle

Carys S. Johnson, Matthew Williams, Kendig Sham, Serena Belluschi, Wenjuan Ma, Xiaonan Wang, Winnie W. Y. Lau, Kerstin B. Kaufmann, Gabriela Krivdova, Emily F. Calderbank, Nicole Mende, Jessica McLeod, Giovanna Mantica, Juan Li, Charlotte Grey-Wilson, Michael Drakopoulos, Shaaezmeen Basheer, Shubhankar Sinha, Evangelia Diamanti, Christina Basford, Nicola K. Wilson, Steven J. Howe, John E. Dick, Berthold Göttgens, Anthony R. Green, Natalie Francis, Elisa Laurenti
Journal: Blood
Blood (2024) 144 (7): 729–741.
https://doi.org/10.1182/blood.2023021426
Published: 2024
Includes: Supplemental data
Journal Articles

Comprehensive and Unbiased Integration Site Analysis in Clinical Gene Therapy.

Richard Gabriel, Anna Paruzynski, Ralph Eckenberg, Cynthia C. Bartholomae, Ali Nowrouzi, Wei Wang, MSc, Kerstin Schwarzwaelder, Anne Arens, Romy Kirsten, Annette Deichmann, Claudia Ball, Steven J. Howe, Alessandra Recchia, Claudia Cattoglio, Kamaljit S. Balaggan, Rafael J. Yáñez-Muñoz, Robin R. Ali, Fulvio Mavilio, Bobby Gaspar, Adrian Thrasher, MD, PhD, Hanno Glimm, MD, Christof von Kalle, William Saurin, Manfred Schmidt
Journal: Blood
Blood (2008) 112 (11): 2351.
https://doi.org/10.1182/blood.V112.11.2351.2351
Published: 2008
Journal Articles

The Clonal Inventory of Gene Corrected Hematopoiesis in Three Successful Clinical Gene Therapy Trials

Kerstin Schwarzwaelder, PhD, Manfred Schmidt, PhD, Annette Deichmann, Steven J. Howe, PhD, Marion G. Ott, MD, Stefan Stein, PhD, Ulrich Siler, MD, Salima Hacein-Bey-Abina, PhD, Hanno Glimm, MD, Dieter Hoelzer, MD, Marina Cavazzana-Calvo, MD, PhD, Adrian J. Thrasher, MD, PhD, Reinhard Seger, MD, Manuel Grez, PhD, Christof von Kalle, MD
Journal: Blood
Blood (2007) 110 (11): 3733.
https://doi.org/10.1182/blood.V110.11.3733.3733
Published: 2007
Journal Articles

Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells

Fang Zhang, Susannah I. Thornhill, Steven J. Howe, Meera Ulaganathan, Axel Schambach, Joanna Sinclair, Christine Kinnon, H. Bobby Gaspar, Michael Antoniou, Adrian J. Thrasher
Journal: Blood
Blood (2007) 110 (5): 1448–1457.
https://doi.org/10.1182/blood-2006-12-060814
Published: 2007
Includes: Supplemental data
Journal Articles

Non-Random Integration and Clone Selection by Lentiviral SIN-LTR Vectors.

Cynthia C. Bartholomae, Annette Deichmann, Manfred Schmidt, PhD, Rafael J. Yanez-Munoz, PhD, Steven J. Howe, PhD, Sonja Schmidt, Claudia Prinz, Adrian J. Thrasher, MD, PhD, Christof von Kalle, MD
Journal: Blood
Blood (2006) 108 (11): 3257.
https://doi.org/10.1182/blood.V108.11.3257.3257
Published: 2006