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Kerstin B. Kaufmann
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Journal Articles

Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle

Carys S. Johnson, Matthew Williams, Kendig Sham, Serena Belluschi, Wenjuan Ma, Xiaonan Wang, Winnie W. Y. Lau, Kerstin B. Kaufmann, Gabriela Krivdova, Emily F. Calderbank, Nicole Mende, Jessica McLeod, Giovanna Mantica, Juan Li, Charlotte Grey-Wilson, Michael Drakopoulos, Shaaezmeen Basheer, Shubhankar Sinha, Evangelia Diamanti, Christina Basford, Nicola K. Wilson, Steven J. Howe, John E. Dick, Berthold Göttgens, Anthony R. Green, Natalie Francis, Elisa Laurenti
Journal: Blood
Blood (2024) 144 (7): 729–741.
https://doi.org/10.1182/blood.2023021426
Published: 2024
Includes: Supplemental data
Journal Articles

Functional Deconvolution of the Leukemia Stem Cell Pool Uncovers Co-Existing Alternative Stem Cell Driven Hierarchies

Helena Boutzen, Alexander Murison, Sayyam Shah, Kerstin B Kaufmann, John E. Dick
Journal: Blood
Blood (2023) 142 (Supplement 1): 5679.
https://doi.org/10.1182/blood-2023-180207
Published: 2023
Journal Articles

The Metabolic Enzyme Hexokinase 2 Localizes to the Nucleus in AML and Normal Hematopoietic Stem/Progenitor Cells to Maintain Stemness

Geethu Emily Thomas, PhDMSc,BSc, Grace Egan, MD, Laura Garcia Prat, PhD BSc, MSc, Botham Aaron, Veronique Voisin, PhD, Elias Orouji, Jordan M Chin, Boaz Nachmias, MDPhD, Kerstin B Kaufmann, PhD, Fieke W Hoff, BSc, Neil Maclean, Rose Hurren, BSc, Xiaoming Wang, Marcela Gronda, MSc, Andrea Arruda, MSc, Mark D. Minden, Gary D Bader, Steven M. Kornblau, MD, John E. Dick, PhD FRS, Aaron D Schimmer, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-135858
Published: 2020
Journal Articles

Dichotomous Regulation of Lysosomes By MYC and Tfeb Controls Hematopoietic Stem Cell Fate

Laura Garcia Prat, PhD BSc, MSc, Kerstin B Kaufmann, PhD, Florin Schneiter, Veronique Voisin, PhD, Alex Murison, Michelle Chan-Seng-Yue, Olga I. Gan, PhD, Jessica L. McLeod, Michelle Shoong, Kristele Pan, Kinam Gupta, Shin-Ichiro Takayanagi, PhD, Elvin Wagenblast, PhD, Weijia Wang, Timm Schroeder, PhD, Stephanie Zhi-Juan Xie, PhD, John E. Dick, PhD FRS
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-142671
Published: 2020
Journal Articles

Divergent Levels of CD112 and INKA1 Define a Subset of Human Hematopoietic Stem Cells That Resists Regenerative Stress to Preserve Stemness

Kerstin B Kaufmann, PhD, Andy G.X. Zeng, BSc, Etienne Coyaud, Laura Garcia Prat, PhD BSc, MSc, Efthymia Papalexi, BA, Estelle MN Laurent, Michelle Chan-Seng-Yue, Olga I. Gan, PhD, Kristele Pan, Jessica L. McLeod, Sasan Zandi, Shin-Ichiro Takayanagi, PhD, Rahul Satija, Brian Raught, Stephanie Zhi-Juan Xie, PhD, John E. Dick, PhD FRS
Journal: Blood
Blood (2020) 136 (Supplement 1): 5.
https://doi.org/10.1182/blood-2020-137725
Published: 2020
Journal Articles

A stemness screen reveals C3orf54/INKA1 as a promoter of human leukemia stem cell latency

Kerstin B. Kaufmann, Laura Garcia-Prat, Qiang Liu, Stanley W. K. Ng, Shin-Ichiro Takayanagi, Amanda Mitchell, Erno Wienholds, Peter van Galen, Christian A. Cumbaa, Mike J. Tsay, Chiara Pastrello, Elvin Wagenblast, Gabriela Krivdova, Mark D. Minden, Eric R. Lechman, Sasan Zandi, Igor Jurisica, Jean C. Y. Wang, Stephanie Z. Xie, John E. Dick
Journal: Blood
Blood (2019) 133 (20): 2198–2211.
https://doi.org/10.1182/blood-2018-10-881441
Published: 2019
Includes: Supplemental data
Journal Articles

A Stemness Screen Reveals C3ORF54/INKA1 As a Gate-Keeper of Human Stem Cell Latency

Kerstin B. Kaufmann, PhD, Laura Garcia Prat, Shin-Ichiro Takayanagi, PhD, Jessica McLeod, BSc, Olga I. Gan, Kristele Pan, Stephanie Zhi-Juan Xie, PhD, John E. Dick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 325.
https://doi.org/10.1182/blood-2018-99-115065
Published: 2018
Journal Articles

Sphingolipid Perturbation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal

Stephanie Zhi-Juan Xie, PhD, Laura Garcia Prat, Veronique Voisin, PhD, Alex Murison, Olga I. Gan, Robin Ferrari, Naoya Takayama, MD PhD, Kerstin B. Kaufmann, PhD, Ishita Patel, Esther Lee, Gareth Holmes, Tiago Medina, PhD, Aditi Vedi, Chiara Luberto, PhD, Gary D Bader, Elisa Laurenti, PhD, Mathieu Lupien, John E. Dick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 170.
https://doi.org/10.1182/blood-2018-170
Published: 2018
Journal Articles

Disturbed Endothelial Blood-Bone Marrow-Barrier In Nox4 Deficient Mice

Maren Weisser, Kerstin B. Kaufmann, Tomer Itkin, PhD, Linping Chen-Wichmann, PhD, Tsvee Lapidot, PhD, Manuel Grez, PhD
Journal: Blood
Blood (2013) 122 (21): 1169.
https://doi.org/10.1182/blood.V122.21.1169.1169
Published: 2013