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Journal Articles

Association of combined IKZF1plus genotype and ABL1 mutations with outcomes in adult BCR::ABL1-positive acute lymphoblastic leukemia

Free
Cheng Wang, Jianfeng Li, Weiyang Liu, Yuchen Yan, Li-Jun Peng, Jiayi Ren, Yongmei Zhu, Xiangqin Weng, Jiong Hu, Yuanfang Liu, Jie Hao, Weiping Zhang, Duohui Jing, Jian-Qing Mi, JIN WANG
Journal: Blood
Blood (2025) 146 (Supplement 1): 6880.
https://doi.org/10.1182/blood-2025-6880
Published: 2025
Journal Articles

A real world study of inotuzumab ozogamicin for the treatment of B-cell acute lymphoblastic leukemia: Multi-center result from SH-ALL group

Free
Yuchen Yan, Ligen Liu, Jie Hao, Xiaofeng Han, Ping Li, Libing Wang, Li Yang, Yong Tang, Cheng Wang, Weiyang Liu, Jiayi Ren, Jiong Hu, Jianmin Yang, Qi Zhu, Aibin Liang, Jian Hou, Xianmin Song, Jianqing Mi, JIN WANG
Journal: Blood
Blood (2025) 146 (Supplement 1): 6830.
https://doi.org/10.1182/blood-2025-6830
Published: 2025
Journal Articles

Simvastatin targets the cholesterol–bile acid axis to improve ALL survival by remodeling the metabolic microenvironment

Free
Junyu Wang, Bo Jiao, Tuantuan Gui, Xuan Liu, Shan-Shan Guo, Cheng Wang, Weiyang Liu, Li-Jun Peng, Jiayi Ren, Ming Zhang, Yun Tan, Duohui Jing, Jian-Qing Mi, Tong Yin, Hai Fang, Sai-Juan Chen, JIN WANG
Journal: Blood
Blood (2025) 146 (Supplement 1): 3362.
https://doi.org/10.1182/blood-2025-3362
Published: 2025
Journal Articles

Long-term follow-up for newly diagnosed BCR::ABL1 negative B cell acute lymphoblastic leukemia from China: 10-year outcome of RJ-ALL 2014 protocol

Free
Jiayi Ren, Li-Jun Peng, Weiyang Liu, Jiong Hu, Cheng Wang, Yuchen Yan, Yuanfang LIU, Weiping Zhang, JIN WANG, Jian-Qing Mi
Journal: Blood
Blood (2025) 146 (Supplement 1): 3333.
https://doi.org/10.1182/blood-2025-3333
Published: 2025
Journal Articles

A Hiplot-Based Web Application for the Rapid Prediction of Adult BCR::ABL1 -Positive and BCR::ABL1 -like B-Cell Precursor Acute Lymphoblastic Leukemia

Free
Jianfeng Li, Yuchen Yan, Cheng Wang, Weiyang Liu, Han Yan, Lingling Zhao, Xiangqin Weng, Yongmei Zhu, Jiayi Ren, Lijun Peng, Jiaojiao Zhang, Yuanfang Liu, Weiping Zhang, Jie Xu, Duohui Jing, Jian-Qing Mi, Jin Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 5926.
https://doi.org/10.1182/blood-2024-210369
Published: 2024
Journal Articles

Flumatinib with Low-Intensity Chemotherapy in Elderly Patients with Newly Diagnosed BCR::ABL1-Positive Acute Lymphoblastic Leukemia

Free
Weiyang Liu, Yuanfang Liu, Yongmei Zhu, Xiangqin Weng, Cheng Wang, Wanyan Ouyang, Jie Xu, Weiping Zhang, Jin Wang, Jian-Qing Mi
Journal: Blood
Blood (2024) 144 (Supplement 1): 5883.
https://doi.org/10.1182/blood-2024-210222
Published: 2024
Journal Articles

Low-Risk Group Identified By a Refined Prognostic System Integrating Both IKZF1 plus genotyping and MRD Assessment in Adult BCR::ABL1 -Positive Acute Lymphoblastic Leukemia

Free
Cheng Wang, Jianfeng Li, Weiyang Liu, Han Yan, Yuchen Yan, Lingling Zhao, Jiayi Ren, Lijun Peng, Jiaojiao Zhang, Yuanfang Liu, Xiangqin Weng, Yongmei Zhu, Weiping Zhang, Jie Xu, Duohui Jing, Jian-Qing Mi, Jin Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1457.
https://doi.org/10.1182/blood-2024-209664
Published: 2024
Journal Articles

The Prognostic Significance of 1-Year Persistent MRD Negativity in Chinese ALL Patients: 5-Year Follow-up Results from RJ-ALL 2014 Trial

Free
Jiayi Ren, Sijie Tang, Weiyang Liu, Xiangqin Weng, Cheng Wang, Lijun Peng, Wenqian Xu, Yuxuan Shang, Jie Hao, Wenyan Yu, Jiaojiao Zhang, Jie Xu, Yuanfang Liu, Weiping Zhang, Jin Wang, Jian-Qing Mi
Journal: Blood
Blood (2023) 142 (Supplement 1): 6057.
https://doi.org/10.1182/blood-2023-189710
Published: 2023
Journal Articles

Dose Escalation of Blinatumomab Is a Better Option for MRD-Positive CR Patients, Results from a Single-Center Real World Study of Blinatumomab for B-Cell Acute Lymphoblastic Leukemia in China

Free
Sijie Tang, Jiayi Ren, Weiyang Liu, Xiangqin Weng, Yongmei Zhu, Cheng Wang, Lijun Peng, Wenqian Xu, Yuxuan Shang, Wenyan Yu, Jiaojiao Zhang, Jie Xu, Yuanfang Liu, Weiping Zhang, Jian-Qing Mi, Jin Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 5885.
https://doi.org/10.1182/blood-2023-189703
Published: 2023
Journal Articles

A Phase II Study of Flumatinib with Chemotherapy for Newly Diagnosed BCR::ABL1-Positive Acute Lymphoblastic Leukemia in Adults: Updated Results from RJ-ALL2020.2A Trial

Free
Weiyang Liu, Cheng Wang, Sijie Tang, Jiayi Ren, Lijun Peng, Yongmei Zhu, Xiangqin Weng, Wanyan Ouyang, Jie Xu, Yuanfang Liu, Weiping Zhang, Jian-Qing Mi, Jin Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 5880.
https://doi.org/10.1182/blood-2023-180326
Published: 2023
Journal Articles

The Promising Third-Generation TKI Olverembatinib in Adult BCR::ABL1-Positive Acute Lymphoblastic Leukemia with T315I Mutation and Relapsed/Refractory Disease

Free
Weiyang Liu, Cheng Wang, Sijie Tang, Jiayi Ren, Lijun Peng, Yongmei Zhu, Xiangqin Weng, Wanyan Ouyang, Jie Xu, Yuanfang Liu, Weiping Zhang, Jin Wang, Jian-Qing Mi
Journal: Blood
Blood (2023) 142 (Supplement 1): 5902.
https://doi.org/10.1182/blood-2023-188733
Published: 2023
Journal Articles

A Robust Long Non-Coding RNA Expression Classifier for Risk Stratification in Pediatric AML

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Jason E Farrar, Jenny L. Smith, Megan Othus, Benjamin J. Huang, Yi-Cheng Wang, Rhonda E. Ries, Tiffany A. Hylkema, Era L Pogosova-Agadjanyan, Sneha Challa, Amanda R. Leonti, Timothy I. Shaw, Timothy Junius Triche, Jr., Alan S. Gamis, Richard Aplenc, Anders E. Kolb, Xiaotu Ma, Derek Stirewalt, Todd A. Alonzo, Soheil Meshinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 9173–9174.
https://doi.org/10.1182/blood-2022-168296
Published: 2022
Journal Articles

The First Report of Third-Generation TKI Olverembatinib in Adult Ph/BCR-ABL1-Positive Acute Lymphoblastic Leukemia with T315I Mutation and Relapsed Disease

Free
Weiyang Liu, Yuanfang Liu, Yongmei Zhu, Xiangqin Weng, Cheng Wang, Wanyan Ouyang, Jie Xu, Jin Wang, Jian-Qing Mi
Journal: Blood
Blood (2022) 140 (Supplement 1): 3266–3267.
https://doi.org/10.1182/blood-2022-166482
Published: 2022
Journal Articles

Expanding the High-Risk Definition for Children with Newly Diagnosed Acute Myeloid Leukemia

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Adam J. Lamble, Rhonda E. Ries, Todd A. Alonzo, Yi-Cheng Wang, Jason E Farrar, Benjamin J. Huang, Matthew A. Kutny, Jessica A. Pollard, Richard Aplenc, Alan S. Gamis, Edward A. Kolb, Todd M. Cooper, Soheil Meshinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 3393–3394.
https://doi.org/10.1182/blood-2022-167680
Published: 2022
Journal Articles

Transcriptome Analysis and Machine Learning Prioritize Therapeutic Strategies for High-Risk Pediatric AML Patients of the KMT2A-Fusion Subgroup

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Alyssa Obermayer, Sijie Yao, Jenny L. Smith, Rhonda E. Ries, Yi-Cheng Wang, Jason E Farrar, Scott N Furlan, Tim Triche, Xiaotu Ma, Benjamin J. Huang, Xuefeng Wang, Soheil Meshinchi, Timothy I. Shaw
Journal: Blood
Blood (2022) 140 (Supplement 1): 3385–3386.
https://doi.org/10.1182/blood-2022-163616
Published: 2022
Journal Articles

Characteristics and Prognostic Effects of DNMT3A Co-Mutations

Free
Alireza Torabi, Todd A. Alonzo, Megan Othus, Robert B. Gerbing, Yi-Cheng Wang, Rhonda E. Ries, Jerald P. Radich, Frederick R. Appelbaum, Kristin O'Dwyer, Harry P. Erba, Martin S. Tallman, Mark R. Litzow, Ehab L. Atallah, Selina M. Luger, Anders E. Kolb, Omar Abdel-Wahab, Derek Stirewalt, Ross L. Levine, Elisabeth Paietta, Soheil Meshinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 745–747.
https://doi.org/10.1182/blood-2022-162526
Published: 2022
Journal Articles

EZH1-PRC2 Identifies a Potential Reservoir for Disease Relapse in Quiescent Cancer Cells Refractory to EZH2 Enzymatic Inhibition

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Evan Healy, Rachel McCole, Craig Monger, James Nolan, Eric Conway, Gerard Brien, Cheng Wang, Hannah K Neikes, Frances Potjewyd, Michiel Vermeulen, Aoibhinn Mooney, Richard Flavin, Elisabeth Vandenberghe, Lindsey I James, Adrian P Bracken
Journal: Blood
Blood (2022) 140 (Supplement 1): 3049–3050.
https://doi.org/10.1182/blood-2022-168762
Published: 2022
Journal Articles

CXCR4 (CD184) Expression in Pediatric AML Is Associated with Bone Marrow Retention, Specific Disease Characteristics, and Worse Outcomes: A Report of 1004 Patients from the Children's Oncology Group AAML1031 Protocol

Free
Andrew J. Menssen, Chad A. Hudson, Todd A. Alonzo, Robert B. Gerbing, Laura Pardo, Fan-Chi Hsu, Loren L. Lott, Fangyan Dai, Keely Ghiradelli, Yi-Cheng Wang, E. Anders Kolb, Todd M. Cooper, Jessica A. Pollard, Michael R. Loken, Richard Aplenc, Lisa Eidenschink Brodersen, Soheil Meshinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 3452–3453.
https://doi.org/10.1182/blood-2022-163682
Published: 2022
Journal Articles

A Phase II Study of Flumatinib with Chemotherapy for Newly Diagnosed Ph/BCR-ABL1-Positive Acute Lymphoblastic Leukemia in Adults：Preliminary Results from RJ-ALL2020.2A Trial

Free
Weiyang Liu, Yuanfang Liu, Yongmei Zhu, Xiangqin Weng, Cheng Wang, Wanyan Ouyang, Jie Xu, Jian-Qing Mi, Jin Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 8981–8982.
https://doi.org/10.1182/blood-2022-165259
Published: 2022
Journal Articles

Integrated Genomic Analysis Identifies UBTF Tandem Duplications As a Subtype-Defining Lesion in Pediatric Acute Myeloid Leukemia

Free
Masayuki Umeda, Jing Ma, Benjamin J. Huang, Kohei Hagiwara, Tamara Westover, Sherif Abdelhamed, Juan Martin Barajas, Melvin Edward Thomas, III, Michael P Walsh, Guangchun Song, Liqing Tian, Yanling Liu, Xiaolong Chen, Pandurang Kolekar, Quang Tran, Scott Foy, Jamie L. Maciaszek, Andrew B Kleist, Amanda R. Leonti, Bensheng Ju, John Easton, Huiyun Wu, Virginia Valentine, Marc Valentine, Yen-Chun Liu, Rhonda E. Ries, Jenny L. Smith, Evan Parganas, Ilaria Iacobucci, Ryan Hiltenbrand, Jonathan Miller, Jason Myers, Evadnie Rampersaud, Delaram Rahbarinia, Michael Rusch, Gang Wu, Hiroto Inaba, Yi-Cheng Wang, Todd A. Alonzo, James R. Downing, Charles G. Mullighan, Stanley B Pounds, M. Madan Babu, Jinghui Zhang, Jeffrey E. Rubnitz, Soheil Meshinchi, Xiaotu Ma, Jeffery M. Klco
Journal: Blood
Blood (2021) 138 (Supplement 2): LBA-4.
https://doi.org/10.1182/blood-2021-155134
Published: 2021