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Lisa Eidenschink Brodersen
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Journal Articles

Treatment Intensification Does Not Improve Outcome for Children with Myeloid Leukemia of Down Syndrome (ML-DS) Who Are MRD-Positive after Induction Therapy: A Report from the Children's Oncology Group

Johann K. Hitzler, Todd A. Alonzo, Robert Gerbing, Jim Wang, Amy Beckman, Betsy Hirsch, Susana C. Raimondi, Karen M Chisholm, Shelton A. Viola, Anupam Verma, Lisa Eidenschink Brodersen, Michael R. Loken, Jeffrey W. Taub, Alan S Gamis, E. Anders Kolb, Todd M Cooper, Jason N. Berman
Journal: Blood
Blood (2024) 144 (Supplement 1): 2949.
https://doi.org/10.1182/blood-2024-202621
Published: 2024
Journal Articles

A Phase 3 Randomized Trial for Patients with De Novo AML Comparing Standard Therapy Including Gemtuzumab Ozogamicin (GO) to CPX-351 with GO - a Report from the Children's Oncology Group

Jessica A. Pollard, Todd A. Alonzo, Robert Gerbing, Matthew A. Kutny, Betsy Hirsch, Gordana Raca, Kasey Leger, Jennifer J. Wilkes, Aman Wadhwa, Zachary Graff, Reena Pabari, Samir Kahwash, Karen M Chisholm, Joseph Chewning, John T. Horan, Richard Aplenc, Katherine Tarlock, Sarah Menig, Olga Militano, Bonnie Ky, Chad A. Hudson, Lisa Eidenschink Brodersen, Michael R. Loken, Soheil Meshinchi, Anders Kolb, Todd M Cooper
Journal: Blood
Blood (2024) 144 (Supplement 1): 967.
https://doi.org/10.1182/blood-2024-205666
Published: 2024
Journal Articles

CXCR4 (CD184) Expression in Pediatric AML Is Associated with Bone Marrow Retention, Specific Disease Characteristics, and Worse Outcomes: A Report of 1004 Patients from the Children's Oncology Group AAML1031 Protocol

Andrew J. Menssen, Chad A. Hudson, Todd A. Alonzo, Robert B. Gerbing, Laura Pardo, Fan-Chi Hsu, Loren L. Lott, Fangyan Dai, Keely Ghiradelli, Yi-Cheng Wang, E. Anders Kolb, Todd M. Cooper, Jessica A. Pollard, Michael R. Loken, Richard Aplenc, Lisa Eidenschink Brodersen, Soheil Meshinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 3452–3453.
https://doi.org/10.1182/blood-2022-163682
Published: 2022
Journal Articles

A Novel Multi-Analytic Clinical Diagnostic Assay to Detect HLA Loss of Heterozygosity in Post-Hematopoietic Cell Transplant Relapse Patients

David Dinauer, Jennifer Schiller, James Nytes, Dina Berchanskiy, Rita Glumm, Susan Gaba, Michael Janasik, Chad A. Hudson, Lisa Eidenschink Brodersen, Wayne Fritschle, Matthew W. Anderson
Journal: Blood
Blood (2022) 140 (Supplement 1): 4964–4965.
https://doi.org/10.1182/blood-2022-159509
Published: 2022
Journal Articles

Pediatric Acute Myeloid Leukemia with Co-Occurring BCR::ABL and CBFA2T3::GLIS2 Dual Fusion with Deep Response to FOLR1-Targeting Antibody Drug Conjugate Stro-002 and Tyrosine Kinase Inhibitor

Kasey Andrews, Soheil Meshinchi, Preethi Marri, Abdul H. Siddiqui, Jacek Polski, Arturo Molina, Joseph Chewning, Lisa Eidenschink Brodersen, Chad A. Hudson, Hamayun Imran
Journal: Blood
Blood (2022) 140 (Supplement 1): 11757–11758.
https://doi.org/10.1182/blood-2022-164629
Published: 2022
Journal Articles

Therapeutic Targeting of CD74 with STRO-001 Antibody-Drug Conjugate in AML and ALL

Quy Le, Amanda R. Leonti, Thao T. Tang, Sommer Castro, Cynthia Nourigat-Mckay, LaKeisha Perkins, Rhonda E. Ries, Jenny L. Smith, Tiffany A. Hylkema, Laura Pardo, Cristina Abrahams, Kristin Bedard, Arturo Molina, Lisa Eidenschink Brodersen, Michael R. Loken, Soheil Meshinchi
Journal: Blood
Blood (2021) 138 (Supplement 1): 509.
https://doi.org/10.1182/blood-2021-151160
Published: 2021
Journal Articles

Increased Expression of CD56 on Plasmacytoid Dendritic Cells in Myeloid Leukemia Associated with Down Syndrome (ML-DS) Is Normal Regeneration and Not Measurable Residual Disease

Chad A Hudson, Laura Pardo, Loren L. Lott, Michael R. Loken, Lisa Eidenschink Brodersen
Journal: Blood
Blood (2021) 138 (Supplement 1): 3433.
https://doi.org/10.1182/blood-2021-149873
Published: 2021
Journal Articles

Multicenter Prospective Evaluation of Diagnostic Potential of Flow Cytometric Aberrancies in Myelodysplastic Syndromes

Wolfgang Kern, Theresia M. Westers, Frauke Bellos, Marie C Bene, Peter Bettelheim, Lisa Eidenschink Brodersen, Kate Burbury, Sung-Chao Chu, Matthew Cullen, Matteo Della Porta, Alan Stewart Dunlop, Ulrika Johansson, Sergio Matarraz, Uta Oelschlaegel, Kiyoyuki Ogata, Anna Porwit, Frank W. M. B. Preijers, Katherina Psarra, Leonie Saft, Dolores Subirá, Elisabeth Weiss, Arjan A. Van de Loosdrecht
Journal: Blood
Blood (2021) 138 (Supplement 1): 3995.
https://doi.org/10.1182/blood-2021-152298
Published: 2021
Journal Articles

Epigenetic Silencing of CD34 in AML and Association with Outcome in KMT2A Fusions

Rhonda E. Ries, Lisa Eidenschink Brodersen, Laura Pardo, Timothy Junius Triche, Jr., Amanda R. Leonti, Jenny L. Smith, Todd A. Alonzo, Jason E Farrar, Yi-Cheng Wang, Alice Dang, Alan S. Gamis, Richard Aplenc, E. Anders Kolb, Michael R. Loken, Soheil Meshinchi
Journal: Blood
Blood (2021) 138 (Supplement 1): 802.
https://doi.org/10.1182/blood-2021-149210
Published: 2021
Journal Articles

Endothelial Cell Niche Promotes Leukemic Transformation of Human Cord Blood Stem/Progenitor Cells Expressing CBFA2T3-GLIS2 Oncogenic Fusion

Quy Le, Tiffany A. Hylkema, Sommer Castro, Jenny L. Smith, Amanda R. Leonti, Thao T. Tang, Cynthia Nourigat-Mckay, LaKeisha Perkins, Laura Pardo, Lisa Eidenschink Brodersen, Michael R. Loken, Rhonda E. Ries, Keith R. Loeb, Soheil Meshinchi
Journal: Blood
Blood (2021) 138 (Supplement 1): 360.
https://doi.org/10.1182/blood-2021-148916
Published: 2021
Journal Articles

Project Stella: Development and Preclinical Assessment of FOLR1-Directed Chimeric Antigen Receptor T Cells in CBF2AT3-GLIS2/RAM AML

Quy Le, Sommer Castro, Thao T. Tang, Cynthia Nourigat-Mckay, LaKeisha Perkins, Tiffany A. Hylkema, Laura Pardo, Jenny L. Smith, Amanda R. Leonti, Rhonda E. Ries, Lisa Eidenschink Brodersen, Michael R. Loken, Soheil Meshinchi
Journal: Blood
Blood (2021) 138 (Supplement 1): 2788.
https://doi.org/10.1182/blood-2021-151836
Published: 2021
Journal Articles

Targeting FOLR1 in High-Risk CBF2AT3-GLIS2 AML with Stro-002 FOLR1-Directed Antibody-Drug Conjugate

Quy Le, Jenny L. Smith, Thao T. Tang, Sommer Castro, Cynthia Nourigat-Mckay, LaKeisha Perkins, Benjamin J. Huang, Rhonda E. Ries, Amanda R. Leonti, Tiffany A. Hylkema, Laura Pardo, Cristina Abrahams, Kristin Bedard, Arturo Molina, Lisa Eidenschink Brodersen, Michael R. Loken, Soheil Meshinchi
Journal: Blood
Blood (2021) 138 (Supplement 1): 209.
https://doi.org/10.1182/blood-2021-153076
Published: 2021
Journal Articles

CEBPA -bZip mutations are associated with favorable prognosis in de novo AML: a report from the Children’s Oncology Group

Clinical Trials & Observations
Katherine Tarlock, Adam J. Lamble, Yi-Cheng Wang, Robert B. Gerbing, Rhonda E. Ries, Michael R. Loken, Lisa Eidenschink Brodersen, Laura Pardo, Amanda Leonti, Jenny L. Smith, Tiffany A. Hylkema, William G. Woods, Todd M. Cooper, E. Anders Kolb, Alan S. Gamis, Richard Aplenc, Todd A. Alonzo, Soheil Meshinchi
Journal: Blood
Blood (2021) 138 (13): 1137–1147.
https://doi.org/10.1182/blood.2020009652
Published: 2021
Includes: Supplemental data
Journal Articles

Newly Diagnosed Childhood AML Patients Treated with Bortezomib Show Superior Survival If CD74 Is Expressed: A Report of 991 Patients from the Children's Oncology Group AAML1031 Protocol

Lisa Eidenschink Brodersen, PhD, Chad A. Hudson, MDPhD, Todd A. Alonzo, PhD, Robert B. Gerbing, MA, Laura Pardo, Amanda R. Leonti, MS, Timothy P. Singleton, MD, Fan-Chi Hsu, PhD, Loren L. Lott, Fangyan Dai, Keely Ghiradelli, E. Anders Kolb, MD, Todd M. Cooper, DO, Jessica A. Pollard, MD, Michael R. Loken, PhD, Richard Aplenc, MD PhD, Soheil Meshinchi, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39.
https://doi.org/10.1182/blood-2020-142659
Published: 2020
Journal Articles

Correlation of CD123 Expression Level with Disease Characteristics and Outcomes in Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group

Adam J. Lamble, MD, Lisa Eidenschink Brodersen, PhD, Todd A. Alonzo, PhD, Jim Wang, Robert B. Gerbing, Laura Pardo, Lillian Sung, MD PhD, Sarah K. Tasian, MD, Todd M Cooper, DO, E. Anders Kolb, MD, Richard Aplenc, MD PhD, Michael R. Loken, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 459.
https://doi.org/10.1182/blood-2019-124587
Published: 2019
Journal Articles

CBFA2T3-GLIS2 induces Malignant Transformation of Primitive CD34+ Cord Blood Cells and Recapitulates Infant Megakaryocytic Leukemia

Tiffany A. Hylkema, BS, Laura Pardo, Keith R. Loeb, MD, Quy Le, PhD, Suzan Imren, MD, Lisa Eidenschink Brodersen, PhD, Michael R. Loken, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1444.
https://doi.org/10.1182/blood-2019-126185
Published: 2019
Journal Articles

CD117 Expression Is Associated with Cytogenetic and Molecular Profiles and Outcome in Pediatric Acute Myeloid Leukemia

Katherine Tarlock, MD, Lisa Eidenschink Brodersen, PhD, Todd A. Alonzo, PhD, Yi-Cheng Wang, Robert B. Gerbing, Laura Pardo, Fangyan Dai, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Jessica A. Pollard, MD, Michael R. Loken, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2699.
https://doi.org/10.1182/blood-2019-127100
Published: 2019
Journal Articles

High-Dose Cytarabine Is Indispensable for the Survival of Children with Myeloid Leukemia of Down Syndrome Despite Negative Minimal Residual Disease Post-Induction

Johann K. Hitzler, MD, Jason Berman, MD, Robert B. Gerbing, Amy Beckman, Betsy A Hirsch, PhD, Susana C. Raimondi, PhD, Todd E Druley, MD PhD, Michael R. Loken, PhD, Lisa Eidenschink Brodersen, PhD, Karen Chisholm, Shelton A. Viola, MD, Jeffrey W. Taub, MD, Alan S Gamis, MD MPH, Todd A. Alonzo, PhD, E. Anders Kolb, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 118.
https://doi.org/10.1182/blood-2019-126723
Published: 2019
Journal Articles

Transcriptome Profiling of Glycosylation Genes Defines Correlation with E-Selectin Ligand Expression and Clinical Outcome in AML

Amanda R. Leonti, MS, Laura Pardo, Todd A. Alonzo, PhD, Robert B. Gerbing, Lisa Eidenschink Brodersen, PhD, Rhonda E. Ries, MA, Jenny L. Smith, MSc, MD, Quy Le, PhD, Richard Aplenc, MD PhD, E. Anders Kolb, MD, John L. Magnani, PhD, William E. Fogler, PhD, Michael R. Loken, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3772.
https://doi.org/10.1182/blood-2019-124525
Published: 2019
Journal Articles

Comprehensive Transcriptome Profiling of Cryptic CBFA2T3-GLIS2 Fusion-Positive AML Defines Novel Therapeutic Options — a COG and Target Pediatric AML Study

Jenny L. Smith, MSc, MD, Rhonda E. Ries, MA, Marianne T. Santaguida, BSc, PhD, Christos Gekas, PhD, Todd A Alonzo, PhD, Robert B Gerbing, MA, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, E. Anders Kolb, MD, Tiffany Hylkema, BS, Lisa Eidenschink Brodersen, PhD, Michael R. Loken, PhD, Hamid Bolouri, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 881.
https://doi.org/10.1182/blood-2018-99-115544
Published: 2018