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Journal Articles

Enhanced Potency of BCMA/CD19 Dual-Targeting Allogeneic CAR-T Cells for Relapsed/ Refractory Multiple Myeloma with 4-1BB/TACI Intracellular Domains

Steven Wang, Iris Pang, Claudia Chang, Michelle Burrascano, Nick DeMarco, Danny Mendoza, Sonia Reyes, Arturo Barcenas, Pastor Nieto, Jose Diaz, Garrett Arauz, Chris Lynn, Tony Nguyen, Connor Reed, Jeannette Connerney, Quy LE, Julia Coronella, Devon J Shedlock

Blood (2024) 144 (Supplement 1): 7093.

https://doi.org/10.1182/blood-2024-211463

Published: 2024

Journal Articles

Potent and Target Specific Cytotoxicity of PRAME TCR Mimic CAR T Cells in KMT2A-Rearranged AML Patient-Derived Xenograft Model

Danielle C Kirkey, Leila Robinson, Tiffany Hylkema, Anisha Loeb, Rhonda E Ries, Cyd McKay, Christina Root, Laura Pardo, Keith R. Loeb, Quy Le, David A. Scheinberg, Soheil Meshinchi

Blood (2023) 142 (Supplement 1): 4821.

https://doi.org/10.1182/blood-2023-188391

Published: 2023

Journal Articles

Integrated Transcriptomics and Proteomics Identifies Therapeutic Targets in Pediatric Acute Myeloid Leukemia

Benjamin J. Huang, Jenny L. Smith, Timothy I. Shaw, Scott N Furlan, Rhonda E. Ries, Amanda R. Leonti, Erin Lynn Crowgey, Lisa Wei, Jason E Farrar, Tim Triche, Xiaotu Ma, Quy Le, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 1296.

https://doi.org/10.1182/blood-2021-153970

Published: 2021

Journal Articles

Therapeutic Targeting of Mesothelin with Chimeric Antigen Receptor Natural Killer Cell Therapy in Acute Myeloid Leukemia

Thao T. Tang, Lindsey F Call, Sommer Castro, Cynthia Nourigat-Mckay, LaKeisha Perkins, Laura Pardo, Amanda R. Leonti, Soheil Meshinchi, Quy Le

Blood (2021) 138 (Supplement 1): 1712.

https://doi.org/10.1182/blood-2021-153156

Published: 2021

Journal Articles

Project Stella: Development and Preclinical Assessment of FOLR1-Directed Chimeric Antigen Receptor T Cells in CBF2AT3-GLIS2/RAM AML

Quy Le, Sommer Castro, Thao T. Tang, Cynthia Nourigat-Mckay, LaKeisha Perkins, Tiffany A. Hylkema, Laura Pardo, Jenny L. Smith, Amanda R. Leonti, Rhonda E. Ries, Lisa Eidenschink Brodersen, Michael R. Loken, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 2788.

https://doi.org/10.1182/blood-2021-151836

Published: 2021

Journal Articles

Immunotherapeutic Targeting of TSLPR with Chimeric Antigen Receptor T Cells in AML

Lindsey F Call, Sommer Castro, Thao T. Tang, Cynthia Nourigat-Mckay, LaKeisha Perkins, Laura Pardo, Amanda R. Leonti, Soheil Meshinchi, Quy Le

Blood (2021) 138 (Supplement 1): 2789.

https://doi.org/10.1182/blood-2021-153815

Published: 2021

Journal Articles

Therapeutic Targeting of CD74 with STRO-001 Antibody-Drug Conjugate in AML and ALL

Quy Le, Amanda R. Leonti, Thao T. Tang, Sommer Castro, Cynthia Nourigat-Mckay, LaKeisha Perkins, Rhonda E. Ries, Jenny L. Smith, Tiffany A. Hylkema, Laura Pardo, Cristina Abrahams, Kristin Bedard, Arturo Molina, Lisa Eidenschink Brodersen, Michael R. Loken, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 509.

https://doi.org/10.1182/blood-2021-151160

Published: 2021

Journal Articles

Biology and Clinical Implications of Complex Landscape of Cooperating Events in FLT3 -ITD Acute Myeloid Leukemia

Katherine Tarlock, Leila Robinson, Todd A. Alonzo, Robert B. Gerbing, Yi-Cheng Wang, Rhonda E. Ries, Amanda R. Leonti, Jenny L. Smith, Tiffany A. Hylkema, Quy Le, Xiaotu Ma, E. Anders Kolb, Richard Aplenc, Jessica A. Pollard, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 3454.

https://doi.org/10.1182/blood-2021-153703

Published: 2021

Journal Articles

Functional Consequence and Therapeutic Targeting of Cryptic ALK Fusions (ALK fus ) in Monosomy7 AML

Makia K. Manselle, Tiffany A. Hylkema, Amanda R. Leonti, Rhonda E. Ries, Quy Le, Scott N Furlan, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 2357.

https://doi.org/10.1182/blood-2021-148179

Published: 2021

Journal Articles

Targeting PRAME with TCR-Mimic CAR T Cells in AML

Anisha M Loeb, Sommer Castro, Cynthia Nourigat-Mckay, LaKeisha Perkins, Laura Pardo, Amanda R. Leonti, Thao T. Tang, Lindsey F Call, Tiffany A. Hylkema, David A. Scheinberg, Soheil Meshinchi, Quy Le

Blood (2021) 138 (Supplement 1): 733.

https://doi.org/10.1182/blood-2021-148677

Published: 2021

Journal Articles

KMT2A Partial Tandem Duplications ( KMT2A -PTD) Is a Rare, but Recurrent Genomic Event in Childhood AML and Associated with High Rate of Co-Occurring FLT3 Mutations

Danielle C. Kirkey, Katherine Tarlock, Rhonda E. Ries, Yi-Cheng Wang, Amanda R. Leonti, Quy Le, Jenny L. Smith, Leila Robinson, Yanling Liu, Quang Tran, Richard Aplenc, Jessica A. Pollard, Anders E. Kolb, Todd A. Alonzo, Xiaotu Ma, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 609.

https://doi.org/10.1182/blood-2021-147565

Published: 2021

Journal Articles

Endothelial Cell Niche Promotes Leukemic Transformation of Human Cord Blood Stem/Progenitor Cells Expressing CBFA2T3-GLIS2 Oncogenic Fusion

Quy Le, Tiffany A. Hylkema, Sommer Castro, Jenny L. Smith, Amanda R. Leonti, Thao T. Tang, Cynthia Nourigat-Mckay, LaKeisha Perkins, Laura Pardo, Lisa Eidenschink Brodersen, Michael R. Loken, Rhonda E. Ries, Keith R. Loeb, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 360.

https://doi.org/10.1182/blood-2021-148916

Published: 2021

Journal Articles

Targeting FOLR1 in High-Risk CBF2AT3-GLIS2 AML with Stro-002 FOLR1-Directed Antibody-Drug Conjugate

Quy Le, Jenny L. Smith, Thao T. Tang, Sommer Castro, Cynthia Nourigat-Mckay, LaKeisha Perkins, Benjamin J. Huang, Rhonda E. Ries, Amanda R. Leonti, Tiffany A. Hylkema, Laura Pardo, Cristina Abrahams, Kristin Bedard, Arturo Molina, Lisa Eidenschink Brodersen, Michael R. Loken, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 209.

https://doi.org/10.1182/blood-2021-153076

Published: 2021

Journal Articles

Generation of CAR-NK Cells Using a Notch-Mediated Cell Expansion and Differentiation Platform

Devikha Chandrasekaran, M.S., Quy Le, PhD, Mary Prieve, PhD, Carrie A Stoltzman, PhD, Jody Cook, BS, Joseph M Blake, BS, Erin B Massey, MS, Soheil Meshinchi, MDPhD, Colleen Delaney, MDMSc

Blood (2020) 136 (Supplement 1): 42.

https://doi.org/10.1182/blood-2020-142813

Published: 2020

Journal Articles

Therapeutic Targeting of Mesothelin in Acute Myeloid Leukemia with Chimeric Antigen Receptor T Cell Therapy

Quy Le, PhD, Sommer Castro, BS, Thao T. Tang, Anisha Loeb, BA, Amanda R. Leonti, MS, Laura Pardo, Michael R. Loken, PhD, Colin Correnti, PhD, Soheil Meshinchi, MDPhD

Blood (2020) 136 (Supplement 1): 11.

https://doi.org/10.1182/blood-2020-143140

Published: 2020

Journal Articles

Mesothelin Expression Is Associated with Extramedullary Disease and Promotes In Vivo Leukemic Growth in Acute Myeloid Leukemia

Katherine Tarlock, MD, Todd A. Alonzo, PhD, Robert B. Gerbing, MA, Quy Le, PhD, Thao T. Tang, Darcy Hamill, DO, Anilkumar Gopalakrishnapillai, PhD, Sonali Barwe, PhD MSc, Rhonda E. Ries, MA, Richard Aplenc, MD PhD, Andrew C. Wood, MD, E. Anders Kolb, MD, Soheil Meshinchi, MDPhD

Blood (2020) 136 (Supplement 1): 38–39.

https://doi.org/10.1182/blood-2020-134821

Published: 2020

Journal Articles

Transcriptome Profiling of Glycosylation Genes Defines Correlation with E-Selectin Ligand Expression and Clinical Outcome in AML

Amanda R. Leonti, MS, Laura Pardo, Todd A. Alonzo, PhD, Robert B. Gerbing, Lisa Eidenschink Brodersen, PhD, Rhonda E. Ries, MA, Jenny L. Smith, MSc, MD, Quy Le, PhD, Richard Aplenc, MD PhD, E. Anders Kolb, MD, John L. Magnani, PhD, William E. Fogler, PhD, Michael R. Loken, PhD, Soheil Meshinchi, MD PhD

Blood (2019) 134 (Supplement_1): 3772.

https://doi.org/10.1182/blood-2019-124525

Published: 2019

Journal Articles

CBFA2T3-GLIS2 induces Malignant Transformation of Primitive CD34+ Cord Blood Cells and Recapitulates Infant Megakaryocytic Leukemia

Tiffany A. Hylkema, BS, Laura Pardo, Keith R. Loeb, MD, Quy Le, PhD, Suzan Imren, MD, Lisa Eidenschink Brodersen, PhD, Michael R. Loken, PhD, Soheil Meshinchi, MD PhD

Blood (2019) 134 (Supplement_1): 1444.

https://doi.org/10.1182/blood-2019-126185

Published: 2019

Journal Articles

The Role of Notch in Endothelial Cell-Mediated Protection of AML Precursors from Targeted Therapy

Quy Le, PhD, Brandon Hadland, MD PhD, Soheil Meshinchi, MD PhD, Irwin D. Bernstein, MD

Blood (2018) 132 (Supplement 1): 3947.

https://doi.org/10.1182/blood-2018-99-119735

Published: 2018

Journal Articles

The Role of Notch in Vascular Endothelial Cell-Mediated Protection of AML Precursors from Targeted Therapy

Quy Le, PhD, Soheil Meshinchi, Brandon Kenneth Hadland, MD PhD, Roland B. Walter, MD PhD, Irwin D. Bernstein, MD

Blood (2016) 128 (22): 2750.

https://doi.org/10.1182/blood.V128.22.2750.2750

Published: 2016

NARROW

Enhanced Potency of BCMA/CD19 Dual-Targeting Allogeneic CAR-T Cells for Relapsed/ Refractory Multiple Myeloma with 4-1BB/TACI Intracellular Domains

Potent and Target Specific Cytotoxicity of PRAME TCR Mimic CAR T Cells in KMT2A-Rearranged AML Patient-Derived Xenograft Model

Integrated Transcriptomics and Proteomics Identifies Therapeutic Targets in Pediatric Acute Myeloid Leukemia

Therapeutic Targeting of Mesothelin with Chimeric Antigen Receptor Natural Killer Cell Therapy in Acute Myeloid Leukemia

Project Stella: Development and Preclinical Assessment of FOLR1-Directed Chimeric Antigen Receptor T Cells in CBF2AT3-GLIS2/RAM AML

Immunotherapeutic Targeting of TSLPR with Chimeric Antigen Receptor T Cells in AML

Therapeutic Targeting of CD74 with STRO-001 Antibody-Drug Conjugate in AML and ALL

Biology and Clinical Implications of Complex Landscape of Cooperating Events in FLT3 -ITD Acute Myeloid Leukemia

Functional Consequence and Therapeutic Targeting of Cryptic ALK Fusions (ALK fus ) in Monosomy7 AML

Targeting PRAME with TCR-Mimic CAR T Cells in AML

KMT2A Partial Tandem Duplications ( KMT2A -PTD) Is a Rare, but Recurrent Genomic Event in Childhood AML and Associated with High Rate of Co-Occurring FLT3 Mutations

Endothelial Cell Niche Promotes Leukemic Transformation of Human Cord Blood Stem/Progenitor Cells Expressing CBFA2T3-GLIS2 Oncogenic Fusion

Targeting FOLR1 in High-Risk CBF2AT3-GLIS2 AML with Stro-002 FOLR1-Directed Antibody-Drug Conjugate

Generation of CAR-NK Cells Using a Notch-Mediated Cell Expansion and Differentiation Platform

Therapeutic Targeting of Mesothelin in Acute Myeloid Leukemia with Chimeric Antigen Receptor T Cell Therapy

Mesothelin Expression Is Associated with Extramedullary Disease and Promotes In Vivo Leukemic Growth in Acute Myeloid Leukemia

Transcriptome Profiling of Glycosylation Genes Defines Correlation with E-Selectin Ligand Expression and Clinical Outcome in AML

CBFA2T3-GLIS2 induces Malignant Transformation of Primitive CD34+ Cord Blood Cells and Recapitulates Infant Megakaryocytic Leukemia

The Role of Notch in Endothelial Cell-Mediated Protection of AML Precursors from Targeted Therapy

The Role of Notch in Vascular Endothelial Cell-Mediated Protection of AML Precursors from Targeted Therapy

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American Society of Hematology

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ASH Publications

American Society of Hematology

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