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Danielle C. Kirkey
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Journal Articles

Dysregulation of Developmental Transcription Factors in Acute Myeloid Leukemia Predicts Poor Outcome and Impacts Adaptive Immune Pathway Genes

Logan K. Wallace, Jack H. Peplinski, Rhonda E. Ries, Danielle C. Kirkey, Xiaotu Ma, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 638.
https://doi.org/10.1182/blood-2024-194524
Published: 2024
Journal Articles

Contrasting Clinical Implications of NRAS Vs. KRAS Mutations in AML - Only KRAS Mutations Are Associated with Adverse Outcome

John N Colgan, Jack H. Peplinski, Danielle C. Kirkey, Adam Lamble, Rhonda E. Ries, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1555.
https://doi.org/10.1182/blood-2024-202833
Published: 2024
Journal Articles

Comprehensive Characterization of Rare Recurrent Mutations in Pediatric AML

Adam Lamble, Rhonda E. Ries, Jack H. Peplinski, Logan K. Wallace, Danielle C. Kirkey, Xiaotu Ma, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 849.
https://doi.org/10.1182/blood-2024-208864
Published: 2024
Journal Articles

Haplo-Insufficiency of RAS Genes Is the Determinant of Outcome in AML

Jack H. Peplinski, Logan K. Wallace, Rhonda E. Ries, Xiaotu Ma, Danielle C. Kirkey, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1562.
https://doi.org/10.1182/blood-2024-208953
Published: 2024
Journal Articles

Preclinical Efficacy of CD276 (B7-H3) CAR T in Acute Myeloid Leukemia

Isabel Lira, Danielle C. Kirkey, Marilena Nicolaidou, Henrike Muller, Marta Barisa, Melia Blankenfeld, Grace Hawkins, Cyd McKay, Christina Root, Laura Pardo, Michael R. Loken, Tiffany Hylkema, Concetta Quintarelli, Franco Locatelli, John Anderson, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 4793.
https://doi.org/10.1182/blood-2024-206227
Published: 2024
Journal Articles

Effective Dual Targeting of PRAME and WT1 with CD33-Gated ARTEMIS® Antibody-TCR Platform in Acute Myeloid Leukemia

Melia Blankenfeld, Danielle C. Kirkey, Guangyan Xiong, Hongbing Zhang, Grace Hawkins, Isabel Lira, Cyd McKay, Christina Root, Concetta Quintarelli, Franco Locatelli, Cheng Liu, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3417.
https://doi.org/10.1182/blood-2024-206204
Published: 2024
Journal Articles

The AML HOX-Ome: The Landscape of Developmental Transcription Factors across Pediatric Acute Myeloid Leukemia

Logan K. Wallace, Jack H. Peplinski, Rhonda E. Ries, Danielle C. Kirkey, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 2925.
https://doi.org/10.1182/blood-2024-211754
Published: 2024
Journal Articles

Potent Target-Specific Efficacy of CAR T Cells Directed Toward the AML and KMT2A-Rearranged Specific Antigen CLEC2A

Danielle C. Kirkey, Grace Hawkins, Melia Blankenfeld, Isabel Lira, Nika Panahi, Margaret G Hines, Seungmin Shin, Tiffany Hylkema, Cyd McKay, Christina Root, Logan K. Wallace, Jack H. Peplinski, Rhonda E. Ries, Concetta Quintarelli, Franco Locatelli, Wei Li, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 2050.
https://doi.org/10.1182/blood-2024-212075
Published: 2024
Journal Articles

Potent and Target Specific Cytotoxicity of PRAME TCR Mimic CAR T Cells in KMT2A-Rearranged AML Patient-Derived Xenograft Model

Danielle C Kirkey, Leila Robinson, Tiffany Hylkema, Anisha Loeb, Rhonda E Ries, Cyd McKay, Christina Root, Laura Pardo, Keith R. Loeb, Quy Le, David A. Scheinberg, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4821.
https://doi.org/10.1182/blood-2023-188391
Published: 2023
Journal Articles

CLEC2A Is a Novel AML-Restricted Immunotherapeutic Target Enriched in KMT2A-Rearranged Acute Myeloid Leukemia

Danielle C Kirkey, Leila Robinson, Derek Janssens, Margaret G Hines, Tiffany Hylkema, Makia K Manselle, Rhonda E Ries, Jack H Peplinski, Logan K Wallace, Dominik Otto, Katherine Tarlock, Steven Henikoff, Wei Li, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 290.
https://doi.org/10.1182/blood-2023-188439
Published: 2023
Journal Articles

LAMP5 Is an AML-Restricted Immunotherapeutic Target Enriched in High-Risk Acute Myeloid Leukemia

Nika Panahi, Tiffany Hylkema, Grace Hawkins, Makia K Manselle, Jack H Peplinski, Logan K Wallace, Rhonda E Ries, Soheil Meshinchi, Danielle C Kirkey
Journal: Blood
Blood (2023) 142 (Supplement 1): 1585.
https://doi.org/10.1182/blood-2023-188352
Published: 2023
Journal Articles

Identification of a Relapse Signature in t(8;21) Pediatric AML

Logan K Wallace, Jack H Peplinski, Rhonda E Ries, Benjamin J Huang, Xiaotu Ma, Scott N Furlan, Danielle C Kirkey, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4318.
https://doi.org/10.1182/blood-2023-189817
Published: 2023
Journal Articles

Identifying a Relapse Signature in CBFB-MYH11 Acute Myeloid Leukemia

Jack H Peplinski, Logan K Wallace, Rhonda E Ries, Benjamin J Huang, Amanda R Leonti, Danielle C Kirkey, Xiaotu Ma, Scott N Furlan, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 2955.
https://doi.org/10.1182/blood-2023-187637
Published: 2023
Journal Articles

CD276 (B7-H3) Is an Immunotherapeutic Target in Acute Myeloid Leukemia with Preclinical Efficacy of Vobramitamab Duocarmazine, an Investigational CD276 Antibody-Drug Conjugate

Danielle C Kirkey, Melia Blankenfeld, Tiffany Hylkema, Deryk Loo, Ashley Ward, Leila Robinson, Jack H Peplinski, Logan K Wallace, Laura Pardo, Andrew J. Menssen, Rhonda E Ries, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 5958.
https://doi.org/10.1182/blood-2023-187450
Published: 2023
Journal Articles

Clinical and Functional Implications of MYC Variants As a New Class of Pathogenic Variants in AML

Danielle C. Kirkey, Xiaoying Wu, Rhonda E. Ries, Tiffany A. Hylkema, Yanling Liu, Pandurang Kolekar, Quang Tran, Alan S. Gamis, Richard Aplenc, Anders E. Kolb, Todd A. Alonzo, Katherine Tarlock, Robert Eisenman, Soheil Meshinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 3395–3396.
https://doi.org/10.1182/blood-2022-168469
Published: 2022
Journal Articles

KMT2A Partial Tandem Duplications ( KMT2A -PTD) Is a Rare, but Recurrent Genomic Event in Childhood AML and Associated with High Rate of Co-Occurring FLT3 Mutations

Danielle C. Kirkey, Katherine Tarlock, Rhonda E. Ries, Yi-Cheng Wang, Amanda R. Leonti, Quy Le, Jenny L. Smith, Leila Robinson, Yanling Liu, Quang Tran, Richard Aplenc, Jessica A. Pollard, Anders E. Kolb, Todd A. Alonzo, Xiaotu Ma, Soheil Meshinchi
Journal: Blood
Blood (2021) 138 (Supplement 1): 609.
https://doi.org/10.1182/blood-2021-147565
Published: 2021