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Jack H Peplinski
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Journal Articles

Contrasting Clinical Implications of NRAS Vs. KRAS Mutations in AML - Only KRAS Mutations Are Associated with Adverse Outcome

John N Colgan, Jack H. Peplinski, Danielle C. Kirkey, Adam Lamble, Rhonda E. Ries, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1555.
https://doi.org/10.1182/blood-2024-202833
Published: 2024
Journal Articles

Comprehensive Characterization of Rare Recurrent Mutations in Pediatric AML

Adam Lamble, Rhonda E. Ries, Jack H. Peplinski, Logan K. Wallace, Danielle C. Kirkey, Xiaotu Ma, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 849.
https://doi.org/10.1182/blood-2024-208864
Published: 2024
Journal Articles

Haplo-Insufficiency of RAS Genes Is the Determinant of Outcome in AML

Jack H. Peplinski, Logan K. Wallace, Rhonda E. Ries, Xiaotu Ma, Danielle C. Kirkey, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1562.
https://doi.org/10.1182/blood-2024-208953
Published: 2024
Journal Articles

The AML HOX-Ome: The Landscape of Developmental Transcription Factors across Pediatric Acute Myeloid Leukemia

Logan K. Wallace, Jack H. Peplinski, Rhonda E. Ries, Danielle C. Kirkey, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 2925.
https://doi.org/10.1182/blood-2024-211754
Published: 2024
Journal Articles

Dysregulation of Developmental Transcription Factors in Acute Myeloid Leukemia Predicts Poor Outcome and Impacts Adaptive Immune Pathway Genes

Logan K. Wallace, Jack H. Peplinski, Rhonda E. Ries, Danielle C. Kirkey, Xiaotu Ma, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 638.
https://doi.org/10.1182/blood-2024-194524
Published: 2024
Journal Articles

Potent Target-Specific Efficacy of CAR T Cells Directed Toward the AML and KMT2A-Rearranged Specific Antigen CLEC2A

Danielle C. Kirkey, Grace Hawkins, Melia Blankenfeld, Isabel Lira, Nika Panahi, Margaret G Hines, Seungmin Shin, Tiffany Hylkema, Cyd McKay, Christina Root, Logan K. Wallace, Jack H. Peplinski, Rhonda E. Ries, Concetta Quintarelli, Franco Locatelli, Wei Li, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 2050.
https://doi.org/10.1182/blood-2024-212075
Published: 2024
Journal Articles

Discovery and Immunotherapeutic Targeting of the Tumor-Specific Target LAMP5 in Acute Myeloid Leukemia

Grace Hawkins, Danielle Kirkey, Nika Panahi, Melia Blankenfeld, Isabel Lira, Tiffany Hylkema, Cyd McKay, Christina Root, Jack H. Peplinski, Logan K. Wallace, Rhonda E. Ries, Laura Pardo, Michael R. Loken, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3413.
https://doi.org/10.1182/blood-2024-204043
Published: 2024
Journal Articles

LAMP5 Is an AML-Restricted Immunotherapeutic Target Enriched in High-Risk Acute Myeloid Leukemia

Nika Panahi, Tiffany Hylkema, Grace Hawkins, Makia K Manselle, Jack H Peplinski, Logan K Wallace, Rhonda E Ries, Soheil Meshinchi, Danielle C Kirkey
Journal: Blood
Blood (2023) 142 (Supplement 1): 1585.
https://doi.org/10.1182/blood-2023-188352
Published: 2023
Journal Articles

Identification of a Relapse Signature in t(8;21) Pediatric AML

Logan K Wallace, Jack H Peplinski, Rhonda E Ries, Benjamin J Huang, Xiaotu Ma, Scott N Furlan, Danielle C Kirkey, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4318.
https://doi.org/10.1182/blood-2023-189817
Published: 2023
Journal Articles

DNMT3A Mutants Are Enriched in NPMc+ AML and Associated with Adverse Outcome in Childhood AML

Rhonda E Ries, Xiaotu Ma, Claudia Tregnago, Todd A. Alonzo, Jim Wang, Tiffany Hylkema, Benjamin J Huang, Alireza Torabi, Jack H Peplinski, Logan K Wallace, Richard Aplenc, Alan S Gamis, Katherine Tarlock, Franco Locatelli, Martina Pigazzi, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4306.
https://doi.org/10.1182/blood-2023-181060
Published: 2023
Journal Articles

CLEC2A Is a Novel AML-Restricted Immunotherapeutic Target Enriched in KMT2A-Rearranged Acute Myeloid Leukemia

Danielle C Kirkey, Leila Robinson, Derek Janssens, Margaret G Hines, Tiffany Hylkema, Makia K Manselle, Rhonda E Ries, Jack H Peplinski, Logan K Wallace, Dominik Otto, Katherine Tarlock, Steven Henikoff, Wei Li, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 290.
https://doi.org/10.1182/blood-2023-188439
Published: 2023
Journal Articles

Disease Monitoring in Acute Myeloid Leukemia with CLEC2A qRT-PCR

Makia K Manselle, Danielle Kirkey, Rhonda E Ries, Tiffany Hylkema, Nika Panahi, Leila Robinson, Logan K Wallace, Jack H Peplinski, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 6021.
https://doi.org/10.1182/blood-2023-190133
Published: 2023
Journal Articles

Identifying a Relapse Signature in CBFB-MYH11 Acute Myeloid Leukemia

Jack H Peplinski, Logan K Wallace, Rhonda E Ries, Benjamin J Huang, Amanda R Leonti, Danielle C Kirkey, Xiaotu Ma, Scott N Furlan, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 2955.
https://doi.org/10.1182/blood-2023-187637
Published: 2023
Journal Articles

CD276 (B7-H3) Is an Immunotherapeutic Target in Acute Myeloid Leukemia with Preclinical Efficacy of Vobramitamab Duocarmazine, an Investigational CD276 Antibody-Drug Conjugate

Danielle C Kirkey, Melia Blankenfeld, Tiffany Hylkema, Deryk Loo, Ashley Ward, Leila Robinson, Jack H Peplinski, Logan K Wallace, Laura Pardo, Andrew J. Menssen, Rhonda E Ries, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 5958.
https://doi.org/10.1182/blood-2023-187450
Published: 2023