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Simona Manni
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Journal Articles

CD19 antigen: From tumor target to safety switch able to improve the safety profile of CAR T cell therapy

Free
Simona Manni, Laura Iaffaldano, Maria Cecilia Quadraccia, Mariasole Aurigemma, Marika Guercio, Simona Caruso, Maria Antonietta De Ioris, Giada Del Baldo, Danielle Kirkey, Soheil Meshinchi, Pietro Merli, Marco Becilli, Francesca Del Bufalo, Biagio De Angelis, Franco Locatelli, Concetta Quintarelli
Journal: Blood
Blood (2025) 146 (Supplement 1): 2541.
https://doi.org/10.1182/blood-2025-2541
Published: 2025
Journal Articles

A novel B7-H3-specific binder enables effective CAR T-cell therapy in an Acute Myeloid Leukemia experimental model

Free
Pamela De Falco, Alessio Ottaviani, Michele Veneruso, Marilena Margiotta, Simona Manni, Marika Guercio, Francesca Del Bufalo, Roberta Castriconi, Cristina Bottino, Danielle Kirkey, Soheil Meshinchi, Pietro Merli, Marco Becilli, Biagio De Angelis, Concetta Quintarelli, Franco Locatelli
Journal: Blood
Blood (2025) 146 (Supplement 1): 6095.
https://doi.org/10.1182/blood-2025-6095
Published: 2025
Journal Articles

CLEC2A, a validated cancer-specific antigen, is an ideal candidate for immunotherapeutic targeting in KMT2A-rearranged AML

Free
Danielle Kirkey, Corinne Summers, Katherine Tarlock, Benjamin Huang, Grace Hawkins, Nika Panahi, Melia Blankenfeld, Isabel Lira, Bruce Liu, Seungmin Shin, Rhonda Ries, Jack H. Peplinski, Simona Manni, Pamela De Falco, Biagio De Angelis, Concetta Quintarelli, Franco Locatelli, Wei Li, Soheil Meshinchi
Journal: Blood
Blood (2025) 146 (Supplement 1): 4123.
https://doi.org/10.1182/blood-2025-4123
Published: 2025
Journal Articles

CAR.CD123-NK Cells Have an Equally Effective but Safer Off-Tumor/on-Target Profile As Compared to CARCD123-T Cells for the Treatment of Acute Myeloid Leukaemia

Free
Simona Caruso, Concetta Quintarelli, Biagio De Angelis, Francesca Del Bufalo, Roselia Ciccone, Samantha Donsante, Gabriele Volpe, Simona Manni, Marika Guercio, Michele Pezzella, Laura Iaffaldano, Domenico Alessandro Silvestris, Matilde Sinibaldi, Stefano Di Cecca, Angela Pitisci, Enrico Velardi, Pietro Merli, Mattia Algeri, Mariachiara Lodi, Valeria Paganelli, Marta Serafini, Mara Riminucci, Franco Locatelli
Journal: Blood
Blood (2022) 140 (Supplement 1): 7369–7370.
https://doi.org/10.1182/blood-2022-166107
Published: 2022