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Marta Serafini
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Journal Articles

The NFκB/COX2 Pathway Mediates the Inhibition of CAR-T Cell Proliferation and Function By Bone Marrow Stroma

Roberto Savoldelli, Alice Pievani, Sarah Tettamanti, Chiara Giacomini, Anna Kozlowska, Marta Serafini, Francesco Dazzi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3426.
https://doi.org/10.1182/blood-2024-209939
Published: 2024
Journal Articles

First-hit SETBP1 mutations cause a myeloproliferative disorder with bone marrow fibrosis

Ilaria Crespiatico, Mattia Zaghi, Cristina Mastini, Deborah D’Aliberti, Mario Mauri, Carl Mirko Mercado, Diletta Fontana, Silvia Spinelli, Valentina Crippa, Elena Inzoli, Beatrice Manghisi, Ivan Civettini, Daniele Ramazzotti, Valentina Sangiorgio, Michele Gengotti, Virginia Brambilla, Andrea Aroldi, Federica Banfi, Cristiana Barone, Roberto Orsenigo, Ludovica Riera, Mara Riminucci, Alessandro Corsi, Massimo Breccia, Alessandro Morotti, Daniela Cilloni, Aldo Roccaro, Antonio Sacco, Fabio Stagno, Marta Serafini, Federica Mottadelli, Giovanni Cazzaniga, Fabio Pagni, Roberto Chiarle, Emanuele Azzoni, Alessandro Sessa, Carlo Gambacorti-Passerini, Elena Maria Elli, Luca Mologni, Rocco Piazza
Journal: Blood
Blood (2024) 143 (14): 1399–1413.
https://doi.org/10.1182/blood.2023021349
Published: 2024
Includes: Supplemental data
Journal Articles

First-Hit SETBP1 Mutations Cause a Myeloproliferative Disorder with Bone Marrow Fibrosis

Ilaria Crespiatico, Mattia Zaghi, Cristina Mastini, Deborah D'Aliberti, Mario Mauri, Carl Mirko Mercado, Diletta Fontana, Silvia Spinelli, Valentina Crippa, Elena Inzoli, Beatrice Manghisi, Ivan Civettini, Daniele Ramazzotti, Valentina Fabiola Ilenia Lavoro, Michele Gengotti, Virginia Brambilla, Andrea Aroldi, Federica Banfi, Cristiana Barone, Roberto Orsenigo, Ludovica Riera, Mara Riminucci, Alessandro Corsi, Massimo Breccia, Alessandro Morotti, Daniela Cilloni, Aldo Roccaro, Antonio Sacco, Fabio Stagno, Marta Serafini, Federica Mottadelli, Giovanni Cazzaniga, Fabio Pagni, Roberto Chiarle, Emanuele Azzoni, Alessandro Sessa, Carlo Gambacorti-Passerini, Elena Maria Elli, Luca Mologni, Rocco Piazza
Journal: Blood
Blood (2023) 142 (Supplement 1): 4135.
https://doi.org/10.1182/blood-2023-189094
Published: 2023
Journal Articles

Bone Marrow Stroma Impairs CAR-T Cell Proliferation and Function: Mechanistic Insights

Francesco Dazzi, Roberto Savoldelli, Alice Pievani, Sarah Tettamanti, Chiara Giacomini, Anna Kozlowska, Marta Serafini
Journal: Blood
Blood (2023) 142 (Supplement 1): 1017.
https://doi.org/10.1182/blood-2023-178675
Published: 2023
Journal Articles

Selective homing of CAR-CIK cells to the bone marrow niche enhances control of the acute myeloid leukemia burden

Marta Biondi, Sarah Tettamanti, Stefania Galimberti, Beatrice Cerina, Chiara Tomasoni, Rocco Piazza, Samantha Donsante, Simone Bido, Vincenzo Maria Perriello, Vania Broccoli, Andrea Doni, Francesco Dazzi, Alberto Mantovani, Gianpietro Dotti, Andrea Biondi, Alice Pievani, Marta Serafini
Journal: Blood
Blood (2023) 141 (21): 2587–2598.
https://doi.org/10.1182/blood.2022018330
Published: 2023
Includes: Supplemental data
Journal Articles

CAR.CD123-NK Cells Have an Equally Effective but Safer Off-Tumor/on-Target Profile As Compared to CARCD123-T Cells for the Treatment of Acute Myeloid Leukaemia

Simona Caruso, Concetta Quintarelli, Biagio De Angelis, Francesca Del Bufalo, Roselia Ciccone, Samantha Donsante, Gabriele Volpe, Simona Manni, Marika Guercio, Michele Pezzella, Laura Iaffaldano, Domenico Alessandro Silvestris, Matilde Sinibaldi, Stefano Di Cecca, Angela Pitisci, Enrico Velardi, Pietro Merli, Mattia Algeri, Mariachiara Lodi, Valeria Paganelli, Marta Serafini, Mara Riminucci, Franco Locatelli
Journal: Blood
Blood (2022) 140 (Supplement 1): 7369–7370.
https://doi.org/10.1182/blood-2022-166107
Published: 2022
Journal Articles

Tuned IL3-Zetakine Coupled to a CD33 Costimulatory Receptor As a Dual CAR for Safer and Selective Targeting of Acute Myeloid Leukemia

Vincenzo Maria Perriello, Maria Caterina Rotiroti, Ilaria Pisani, Stefania Galimberti, Gaia Alberti, Giulia Pianigiani, Valerio Ciaurro, Andrea Marra, Marcella Sabino, Valentina Tini, Federica Mezzasoma, Francesco Morena, Sabata Martino, Domenico Salerno, Julian François Ashby, Brittany Wingham, Marta Serafini, Maria Paola Martelli, Brunangelo Falini, Andrea Biondi, Sarah Tettamanti
Journal: Blood
Blood (2022) 140 (Supplement 1): 10237–10238.
https://doi.org/10.1182/blood-2022-166555
Published: 2022
Journal Articles

Overexpression of CXCR4 Enhances the Efficacy of CAR-T Therapy for Acute Myeloid Leukemia

Marta Biondi, Stefania Galimberti, Beatrice Cerina, Chiara Tomasoni, Gianpietro Dotti, Sarah Tettamanti, Andrea Biondi, Alice Pievani, Marta Serafini
Journal: Blood
Blood (2022) 140 (Supplement 1): 4500–4501.
https://doi.org/10.1182/blood-2022-163130
Published: 2022
Journal Articles

CD123 and CD33 Co-Targeting By Balanced Signaling on CAR-CIK Cells Reduces Potential Off-Target Toxicity While Preserving the Anti-Leukemic Activity of Acute Myeloid Leukemia

Vincenzo Maria Perriello, Maria Caterina Rotiroti, Ilaria Pisani, Gaia Alberti, Giulia Pianigiani, Roberta Rossi, Valerio Ciaurro, Marta Serafini, Maria Paola Martelli, Brunangelo Falini, Andrea Biondi, Sarah Tettamanti
Journal: Blood
Blood (2021) 138 (Supplement 1): 1699.
https://doi.org/10.1182/blood-2021-150487
Published: 2021
Journal Articles

Combining the Expression of CD33.CAR and CXCR4 to Increase CAR-CIK Cell Homing to Bone Marrow Niche and Leukemic Stem Cell Eradication in Acute Myeloid Leukemia

Marta Biondi, Beatrice Cerina, Chiara Tomasoni, Gianpietro Dotti, Sarah Tettamanti, Andrea Biondi, Alice Pievani, Marta Serafini
Journal: Blood
Blood (2021) 138 (Supplement 1): 2791.
https://doi.org/10.1182/blood-2021-152394
Published: 2021
Journal Articles

Preclinical Assessment of Non-Virally Engineered CD33.CAR Cytokine-Induced Killer (CIK) Cells in Chemoresistant AML Patient-Derived Xenografts

Maria Caterina Rotiroti, PhD, Chiara Buracchi, PhD, Silvia Arcangeli, PhD, Chiara F Magnani, PhD, Claudia Cappuzzello, PhD, Zsuzsanna Izsvak, PhD, Stefania Galimberti, PhD, Maria Grazia Valsecchi, PhD, Giuseppe Dastoli, MD, Marta Serafini, PhD, Ettore Biagi, MD, Andrea Biondi, MD, Sarah Tettamanti, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2665.
https://doi.org/10.1182/blood-2019-130399
Published: 2019
Journal Articles

Neonatal bone marrow transplantation prevents bone pathology in a mouse model of mucopolysaccharidosis type I

Alice Pievani, Isabella Azario, Laura Antolini, Tsutomu Shimada, Pravin Patel, Cristina Remoli, Benedetta Rambaldi, Maria Grazia Valsecchi, Mara Riminucci, Andrea Biondi, Shunji Tomatsu, Marta Serafini
Journal: Blood
Blood (2015) 125 (10): 1662–1671.
https://doi.org/10.1182/blood-2014-06-581207
Published: 2015
Includes: Supplemental data
Journal Articles

Neonatal Bone Marrow Transplantation Prevents Bone Pathology in a Mouse Model of Mucopolysaccharidosis Type I

Alice Pievani, PhD, Isabella Maria Rebecca Azario, Laura Antolini, Tsutomu Shimada, Pravin Patel, Cristina Remoli, Benedetta Rambaldi, Maria Grazia Valsecchi, Mara Riminucci, Andrea Biondi, Shunji Tomatsu, Marta Serafini
Journal: Blood
Blood (2014) 124 (21): 649.
https://doi.org/10.1182/blood.V124.21.649.649
Published: 2014